GB1288205A - - Google Patents
Info
- Publication number
- GB1288205A GB1288205A GB175570A GB175570A GB1288205A GB 1288205 A GB1288205 A GB 1288205A GB 175570 A GB175570 A GB 175570A GB 175570 A GB175570 A GB 175570A GB 1288205 A GB1288205 A GB 1288205A
- Authority
- GB
- United Kingdom
- Prior art keywords
- amines
- amine
- salts
- racemic
- isopropylidene
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 150000001412 amines Chemical class 0.000 abstract 7
- 150000003839 salts Chemical class 0.000 abstract 5
- 239000003795 chemical substances by application Substances 0.000 abstract 3
- 239000002253 acid Substances 0.000 abstract 2
- KWTSXDURSIMDCE-MRVPVSSYSA-N (R)-amphetamine Chemical compound C[C@@H](N)CC1=CC=CC=C1 KWTSXDURSIMDCE-MRVPVSSYSA-N 0.000 abstract 1
- PJXWCRXOPLGFLX-UHFFFAOYSA-N 2-(benzylamino)propan-1-ol Chemical compound OCC(C)NCC1=CC=CC=C1 PJXWCRXOPLGFLX-UHFFFAOYSA-N 0.000 abstract 1
- 101000653791 Bos taurus Protein S100-A12 Proteins 0.000 abstract 1
- VBUYCZFBVCCYFD-UHFFFAOYSA-N D-arabino-2-Hexulosonic acid Natural products OCC(O)C(O)C(O)C(=O)C(O)=O VBUYCZFBVCCYFD-UHFFFAOYSA-N 0.000 abstract 1
- 150000007513 acids Chemical class 0.000 abstract 1
- 125000002723 alicyclic group Chemical group 0.000 abstract 1
- 125000001931 aliphatic group Chemical group 0.000 abstract 1
- -1 amine salts Chemical class 0.000 abstract 1
- 125000003118 aryl group Chemical group 0.000 abstract 1
- CREXVNNSNOKDHW-UHFFFAOYSA-N azaniumylideneazanide Chemical group N[N] CREXVNNSNOKDHW-UHFFFAOYSA-N 0.000 abstract 1
- WTDRDQBEARUVNC-UHFFFAOYSA-N dopa Chemical compound OC(=O)C(N)CC1=CC=C(O)C(O)=C1 WTDRDQBEARUVNC-UHFFFAOYSA-N 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 238000001640 fractional crystallisation Methods 0.000 abstract 1
- 125000000623 heterocyclic group Chemical group 0.000 abstract 1
- 229910052500 inorganic mineral Inorganic materials 0.000 abstract 1
- 229950005223 levamfetamine Drugs 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 239000011707 mineral Substances 0.000 abstract 1
- 150000003141 primary amines Chemical class 0.000 abstract 1
- 150000003335 secondary amines Chemical class 0.000 abstract 1
- 150000003512 tertiary amines Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
- C07D217/12—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring
- C07D217/18—Aralkyl radicals
- C07D217/20—Aralkyl radicals with oxygen atoms directly attached to the aromatic ring of said aralkyl radical, e.g. papaverine
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C215/00—Compounds containing amino and hydroxy groups bound to the same carbon skeleton
- C07C215/02—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton
- C07C215/04—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being saturated
- C07C215/06—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being saturated and acyclic
- C07C215/08—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being saturated and acyclic with only one hydroxy group and one amino group bound to the carbon skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D221/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
- C07D221/02—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00 condensed with carbocyclic rings or ring systems
- C07D221/22—Bridged ring systems
- C07D221/28—Morphinans
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Other In-Based Heterocyclic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US79533369A | 1969-01-30 | 1969-01-30 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1288205A true GB1288205A (cg-RX-API-DMAC7.html) | 1972-09-06 |
Family
ID=25165275
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB175570A Expired GB1288205A (cg-RX-API-DMAC7.html) | 1969-01-30 | 1970-01-14 |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US3682925A (cg-RX-API-DMAC7.html) |
| JP (1) | JPS5039652B1 (cg-RX-API-DMAC7.html) |
| BE (1) | BE745032A (cg-RX-API-DMAC7.html) |
| CH (1) | CH526486A (cg-RX-API-DMAC7.html) |
| DE (1) | DE2003486C3 (cg-RX-API-DMAC7.html) |
| DK (1) | DK126422B (cg-RX-API-DMAC7.html) |
| FR (1) | FR2029706A1 (cg-RX-API-DMAC7.html) |
| GB (1) | GB1288205A (cg-RX-API-DMAC7.html) |
| NL (1) | NL152233B (cg-RX-API-DMAC7.html) |
| SE (1) | SE361168B (cg-RX-API-DMAC7.html) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4283340A (en) * | 1977-06-13 | 1981-08-11 | Pfizer Inc. | Ascorbic acid intermediates |
| DE3436179A1 (de) * | 1984-10-03 | 1986-04-10 | Merck Patent Gmbh, 6100 Darmstadt | Verfahren zur herstellung optisch aktiver amine |
| US5039801A (en) * | 1985-12-20 | 1991-08-13 | The United States Of America As Represented By The Department Of Health & Human Services | Thermal fragmentation of methylbenzylurea disastereomers or secondary amines and preparation of optically active secondary amines |
| DE19927412A1 (de) | 1999-06-16 | 2000-12-21 | Bayer Ag | Verfahren zur Enantiomerenanreicherung von cis-8-Benzyl-7,9-dioxo-2,8-diazabicyclo [4.3.0]nonan |
| AU2003253036A1 (en) * | 2002-07-09 | 2004-01-23 | Lonza Ag | Process for the preparation of optically active 3-n-methylamino-1-(2-thienyl)-1-propanol |
| WO2004031168A2 (en) * | 2002-10-07 | 2004-04-15 | Lonza Ag | Processes and intermediates for the preparation of optically active 3-amino-1-(2-thienyl)-1-propanol derivatives |
| US8148527B1 (en) | 2011-01-18 | 2012-04-03 | Divi's Laboratories, Ltd. | Resolution of 1-(4-methoxybenzyl)-octahydro-isoquinoline |
| CN103319406A (zh) * | 2012-03-20 | 2013-09-25 | 迪维斯实验室有限公司 | 1-(4-甲氧苄基)-八氢-异喹啉的拆分 |
| AR110150A1 (es) | 2016-11-09 | 2019-02-27 | Roivant Sciences Gmbh | Procesos para la preparación de inhibidores de tph1 |
| CN112707901B (zh) * | 2020-12-07 | 2022-03-22 | 泰安汉威集团有限公司 | 一种化合物a的制备方法 |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB707903A (en) * | 1951-05-10 | 1954-04-28 | British Drug Houses Ltd | Improvements in or relating to the resolution of isomeric mixtures of 1-p-nitrophenyl-2-aminopropane-1,3-diol |
| GB738064A (en) * | 1953-07-15 | 1955-10-05 | Lepetit Spa | Process for the resolution of racemic threo-1-phenyl-2-amino-1,3-propanediol |
| US2957886A (en) * | 1956-10-19 | 1960-10-25 | Monsanto Chemicals | Resolution procedures and apparatus therefor |
-
1969
- 1969-01-30 US US795333*A patent/US3682925A/en not_active Expired - Lifetime
-
1970
- 1970-01-13 CH CH39470A patent/CH526486A/de not_active IP Right Cessation
- 1970-01-14 GB GB175570A patent/GB1288205A/en not_active Expired
- 1970-01-27 DE DE2003486A patent/DE2003486C3/de not_active Expired
- 1970-01-28 BE BE745032D patent/BE745032A/xx unknown
- 1970-01-29 FR FR7003161A patent/FR2029706A1/fr not_active Withdrawn
- 1970-01-29 DK DK42670AA patent/DK126422B/da unknown
- 1970-01-30 NL NL707001366A patent/NL152233B/xx unknown
- 1970-01-30 JP JP45008354A patent/JPS5039652B1/ja active Pending
- 1970-01-30 SE SE01253/70A patent/SE361168B/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| NL7001366A (cg-RX-API-DMAC7.html) | 1970-08-03 |
| SE361168B (cg-RX-API-DMAC7.html) | 1973-10-22 |
| CH526486A (de) | 1972-08-15 |
| DE2003486A1 (de) | 1970-08-13 |
| DE2003486B2 (de) | 1978-08-24 |
| JPS5039652B1 (cg-RX-API-DMAC7.html) | 1975-12-18 |
| DK126422B (da) | 1973-07-16 |
| NL152233B (nl) | 1977-02-15 |
| DE2003486C3 (de) | 1979-04-26 |
| BE745032A (fr) | 1970-07-28 |
| FR2029706A1 (cg-RX-API-DMAC7.html) | 1970-10-23 |
| US3682925A (en) | 1972-08-08 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PS | Patent sealed [section 19, patents act 1949] | ||
| PCNP | Patent ceased through non-payment of renewal fee |