GB1308264A - 1-n-benzyl-beta-methoxy-3-trifluoromethylphenethylamine - Google Patents
1-n-benzyl-beta-methoxy-3-trifluoromethylphenethylamineInfo
- Publication number
- GB1308264A GB1308264A GB3515671A GB3515671A GB1308264A GB 1308264 A GB1308264 A GB 1308264A GB 3515671 A GB3515671 A GB 3515671A GB 3515671 A GB3515671 A GB 3515671A GB 1308264 A GB1308264 A GB 1308264A
- Authority
- GB
- United Kingdom
- Prior art keywords
- optically active
- isomer
- treated
- organic acid
- methoxy
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Landscapes
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
1308264 I-N-Benzyl-#-methoxy-3-trifluoromethyl-phenylethylamine SMITH KLINE & FRENCH LABORATORIES 27 July 1971 [28 July 1970] 35156/71 Heading C2C [Also in Division A5] The title compound is prepared by treating the dl form in a lower alkanol with an optically active levorotatory organic acid to form the corresponding optically active salt which is then treated with a base to liberate the l-isomer. Alternatively an aqueous lower alkanol solution of the racemic mixture is treated with an optically active organic acid, (e.g. D-tartaric acid) to remove the d-isomer of the amine then the mother liquor is made basic and subsequently treated with the corresponding enantiomer of the optically active organic acid (e.g. L-tartaric acid) to form a salt from which the l-isomer of the amine is subsequently liberated. The title compound may be. converted into pharmaceutically acceptable acid addition salts such as the hydrochloride.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US5904170A | 1970-07-28 | 1970-07-28 |
Publications (1)
Publication Number | Publication Date |
---|---|
GB1308264A true GB1308264A (en) | 1973-02-21 |
Family
ID=22020434
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
GB3515671A Expired GB1308264A (en) | 1970-07-28 | 1971-07-27 | 1-n-benzyl-beta-methoxy-3-trifluoromethylphenethylamine |
Country Status (7)
Country | Link |
---|---|
AU (1) | AU449620B2 (en) |
BE (1) | BE769983A (en) |
CA (1) | CA993454A (en) |
DE (1) | DE2137807A1 (en) |
FR (1) | FR2100957B1 (en) |
GB (1) | GB1308264A (en) |
ZA (1) | ZA714501B (en) |
Family Cites Families (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
NL143905B (en) * | 1965-06-28 | 1974-11-15 | Melville Sahyun Handelende Ond | PROCESS FOR PREPARING ALKOXYTRIFLUORMETHYLPHENYL ALKYLAMINS AND MEDICINAL PRODUCTS CONTAINING THESE COMPOUNDS AND THE MEDICINAL PRODUCTS THEREFORE OBTAINED. |
-
1971
- 1971-07-06 CA CA117,482A patent/CA993454A/en not_active Expired
- 1971-07-07 ZA ZA714501A patent/ZA714501B/en unknown
- 1971-07-12 AU AU31125/71A patent/AU449620B2/en not_active Expired
- 1971-07-14 BE BE769983A patent/BE769983A/en unknown
- 1971-07-19 FR FR7126369A patent/FR2100957B1/fr not_active Expired
- 1971-07-27 GB GB3515671A patent/GB1308264A/en not_active Expired
- 1971-07-28 DE DE19712137807 patent/DE2137807A1/en active Pending
Also Published As
Publication number | Publication date |
---|---|
DE2137807A1 (en) | 1972-02-10 |
AU449620B2 (en) | 1974-06-20 |
BE769983A (en) | 1972-01-14 |
FR2100957B1 (en) | 1974-11-15 |
AU3112571A (en) | 1973-01-18 |
FR2100957A1 (en) | 1972-03-24 |
ZA714501B (en) | 1972-03-29 |
CA993454A (en) | 1976-07-20 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
PS | Patent sealed | ||
PLNP | Patent lapsed through nonpayment of renewal fees |