GB1154743A - Aminoethanols - Google Patents
AminoethanolsInfo
- Publication number
- GB1154743A GB1154743A GB21778/66A GB2177866A GB1154743A GB 1154743 A GB1154743 A GB 1154743A GB 21778/66 A GB21778/66 A GB 21778/66A GB 2177866 A GB2177866 A GB 2177866A GB 1154743 A GB1154743 A GB 1154743A
- Authority
- GB
- United Kingdom
- Prior art keywords
- alkyl
- group
- hydrogen atom
- radical
- novel compounds
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- UJPKMTDFFUTLGM-UHFFFAOYSA-N 1-aminoethanol Chemical class CC(N)O UJPKMTDFFUTLGM-UHFFFAOYSA-N 0.000 title abstract 2
- 125000000217 alkyl group Chemical group 0.000 abstract 3
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 3
- 125000001797 benzyl group Chemical group [H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])* 0.000 abstract 2
- 125000002915 carbonyl group Chemical group [*:2]C([*:1])=O 0.000 abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 2
- KAESVJOAVNADME-UHFFFAOYSA-N 1H-pyrrole Natural products C=1C=CNC=1 KAESVJOAVNADME-UHFFFAOYSA-N 0.000 abstract 1
- 125000002252 acyl group Chemical group 0.000 abstract 1
- 125000003545 alkoxy group Chemical group 0.000 abstract 1
- 150000001350 alkyl halides Chemical class 0.000 abstract 1
- 125000003710 aryl alkyl group Chemical group 0.000 abstract 1
- 125000003118 aryl group Chemical group 0.000 abstract 1
- 230000002567 autonomic effect Effects 0.000 abstract 1
- 210000000748 cardiovascular system Anatomy 0.000 abstract 1
- 210000003169 central nervous system Anatomy 0.000 abstract 1
- 239000012634 fragment Substances 0.000 abstract 1
- 125000005843 halogen group Chemical group 0.000 abstract 1
- 238000005984 hydrogenation reaction Methods 0.000 abstract 1
- 125000004356 hydroxy functional group Chemical group O* 0.000 abstract 1
- 239000004615 ingredient Substances 0.000 abstract 1
- 150000007522 mineralic acids Chemical class 0.000 abstract 1
- 150000007524 organic acids Chemical class 0.000 abstract 1
- 230000002093 peripheral effect Effects 0.000 abstract 1
- 239000000825 pharmaceutical preparation Substances 0.000 abstract 1
- 125000000168 pyrrolyl group Chemical group 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/30—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
- C07D207/32—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
- C07D207/323—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms with only hydrogen atoms or radicals containing only hydrogen and carbon atoms directly attached to the ring nitrogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/30—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
- C07D207/32—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
- C07D207/33—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms with substituted hydrocarbon radicals, directly attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/30—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
- C07D207/32—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
- C07D207/33—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms with substituted hydrocarbon radicals, directly attached to ring carbon atoms
- C07D207/335—Radicals substituted by nitrogen atoms not forming part of a nitro radical
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pyrrole Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pyridine Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Hydrogenated Pyridines (AREA)
Priority Applications (41)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB53844/68A GB1154745A (en) | 1966-05-17 | 1966-05-17 | Haloketones |
| GB21777/66A GB1154742A (en) | 1966-05-17 | 1966-05-17 | Pyrrylamino Ketones |
| GB21778/66A GB1154743A (en) | 1966-05-17 | 1966-05-17 | Aminoethanols |
| GB21779/66A GB1154744A (en) | 1966-05-17 | 1966-05-17 | Disubstituted Aminoethanols |
| IL27934A IL27934A (en) | 1966-05-17 | 1967-05-08 | 1-pyrryl-2-aminoethanols,their preparation and pharmaceutical compositions containing them |
| US636649A US3539589A (en) | 1966-05-17 | 1967-05-08 | 1-(alpha-pyrryl)-2-amino ethanols |
| LU53619D LU53619A1 (en, 2012) | 1966-05-17 | 1967-05-08 | |
| US636625A US3558652A (en) | 1966-05-17 | 1967-05-08 | N-monosubstituted pyrrylaminoethanols |
| IL27933A IL27933A (en) | 1966-05-17 | 1967-05-08 | Pyrillary aminoalkyl ketones, their preparation and pharmaceutical preparations containing them |
| DE19671720018 DE1720018B2 (de) | 1966-05-17 | 1967-05-11 | N-monosubstituierte pyrrylaminoaethanole |
| DE1795841A DE1795841C3 (de) | 1966-05-17 | 1967-05-12 | H2'-Chlor)-benzyl-2-di-sec.-butylamino-acetyl-pyrrol, seine Salze und Verfahren zu deren Herstellung |
| DE1720019A DE1720019C3 (de) | 1966-05-17 | 1967-05-12 | 1 -Benzyl-2-aminoacetyl-pyrrol-Derivate, deren Salze und Verfahren zu ihrer Herstellung |
| DE1720020A DE1720020B2 (de) | 1966-05-17 | 1967-05-12 | 1- eckige Klammer auf alpha-(N-o-Chlorbenzyl)-pyrryl eckige Klammer zu -2-di-sec-burylamino-äthanol, dessen Säureadditionssalze und Verfahren zu seiner Herstellung |
| AT448267A AT278770B (de) | 1966-05-17 | 1967-05-12 | Verfahren zur Herstellung von neuen N-substituierten Pyrrylaminoäthanolen und ihren Salzen |
| NO168124A NO123034B (en, 2012) | 1966-05-17 | 1967-05-12 | |
| NO168123A NO121950B (en, 2012) | 1966-05-17 | 1967-05-12 | |
| YU0973/67A YU32531B (en) | 1966-05-17 | 1967-05-16 | Postupak za dobijanje ketoi hidroksi-amino-pirol derivata |
| DK254767AA DK133943B (da) | 1966-05-17 | 1967-05-16 | Analogifremgangsmåde til fremstilling af N-substituerede pyrrylaminoethanoler eller salte deraf. |
| DK254867A DK132411C (da) | 1966-05-17 | 1967-05-16 | Analogifremgangsmade til fremstilling af pyrrylaminoketonderivater eller syreadditionssalte deraf |
| ES340591A ES340591A1 (es) | 1966-05-17 | 1967-05-16 | Procedimiento para preparar derivados de pirrol. |
| GR670136604A GR36604B (el) | 1966-05-17 | 1967-05-16 | Μεθοδος δια την παρασκευην πυρρυλ - αμινοαιθανολων. |
| FR106670A FR6770M (en, 2012) | 1966-05-17 | 1967-05-17 | |
| SE6867/67A SE313565B (en, 2012) | 1966-05-17 | 1967-05-17 | |
| NL6706840.A NL156394B (nl) | 1966-05-17 | 1967-05-17 | Werkwijze voor het bereiden van 1-(2-pyrryl)-2-aminoethanolen, alsmede van een farmaceutisch preparaat met werking op het cardiovasculaire systeem, dat zulk een verbinding bevat. |
| NL676706839A NL141087B (nl) | 1966-05-17 | 1967-05-17 | Werkwijze ter bereiding van pyrrolylaminoketonderivaten bevattende geneesmiddelen met een werking op het centrale zenuwstelsel, de aldus verkregen gevormde geneesmiddelen, alsmede werkwijze voor het bereiden van de pyrrolylaminoketonderivaten. |
| BR189534/67A BR6789534D0 (pt) | 1966-05-17 | 1967-05-17 | Compostos pirrolicos e processo de preparacao dos mesmos |
| SE6866/67A SE313564B (en, 2012) | 1966-05-17 | 1967-05-17 | |
| FI671407A FI48348C (fi) | 1966-05-17 | 1967-05-17 | Terapeuttisesti käytettäviä pyrryyliaminoketonijohdannaisia. |
| FR106668A FR6663M (en, 2012) | 1966-05-17 | 1967-05-17 | |
| FR106669A FR6769M (en, 2012) | 1966-05-17 | 1967-05-17 | |
| BE698567D BE698567A (en, 2012) | 1966-05-17 | 1967-05-17 | |
| BE698568D BE698568A (en, 2012) | 1966-05-17 | 1967-05-17 | |
| CH694267A CH484108A (de) | 1966-05-17 | 1967-05-17 | Verfahren zur Herstellung von Pyrrylaminoäthanolen |
| CH694067A CH484107A (de) | 1966-05-17 | 1967-05-17 | Verfahren zur Herstellung von Pyrrolaminoketonen |
| FI671408A FI48349C (fi) | 1966-05-17 | 1967-05-17 | Terapeuttisesti käytettäviä substituoituja pyrryyliaminoetanoleja. |
| NL676706841A NL149375B (nl) | 1966-05-17 | 1967-05-17 | Werkwijze voor het bereiden van een geneesmiddel met een werking op het centrale of perifere zenuwstelsel dat als actief bestanddeel een 2-aminoethanolderivaat bevat. |
| FR117532A FR1544722A (fr) | 1966-05-17 | 1967-08-10 | Dérivés du pyrrole et leur procédé de fabrication |
| US78262A US3706750A (en) | 1966-05-17 | 1970-10-05 | Pyrrylaminoketone derivatives |
| CY63472A CY634A (en) | 1966-05-17 | 1972-02-23 | Disubstituted aminoethanols |
| YU2345/73A YU36700B (en) | 1966-05-17 | 1973-09-04 | Process for obtaining new keto-and hydroxyamino-pyrrol derivatives |
| DK303275A DK133944B (da) | 1966-05-17 | 1975-07-04 | 1-Benzyl-2-aminoacetylpyrrolforbindelser til anvendelse ved fremstillingen af pyrrylaminoethanolforbindelser. |
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB21777/66A GB1154742A (en) | 1966-05-17 | 1966-05-17 | Pyrrylamino Ketones |
| GB53844/68A GB1154745A (en) | 1966-05-17 | 1966-05-17 | Haloketones |
| GB21779/66A GB1154744A (en) | 1966-05-17 | 1966-05-17 | Disubstituted Aminoethanols |
| GB21778/66A GB1154743A (en) | 1966-05-17 | 1966-05-17 | Aminoethanols |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1154743A true GB1154743A (en) | 1969-06-11 |
Family
ID=27448540
Family Applications (4)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB21777/66A Expired GB1154742A (en) | 1966-05-17 | 1966-05-17 | Pyrrylamino Ketones |
| GB21779/66A Expired GB1154744A (en) | 1966-05-17 | 1966-05-17 | Disubstituted Aminoethanols |
| GB21778/66A Expired GB1154743A (en) | 1966-05-17 | 1966-05-17 | Aminoethanols |
| GB53844/68A Expired GB1154745A (en) | 1966-05-17 | 1966-05-17 | Haloketones |
Family Applications Before (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB21777/66A Expired GB1154742A (en) | 1966-05-17 | 1966-05-17 | Pyrrylamino Ketones |
| GB21779/66A Expired GB1154744A (en) | 1966-05-17 | 1966-05-17 | Disubstituted Aminoethanols |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB53844/68A Expired GB1154745A (en) | 1966-05-17 | 1966-05-17 | Haloketones |
Country Status (18)
| Country | Link |
|---|---|
| US (3) | US3558652A (en, 2012) |
| AT (1) | AT278770B (en, 2012) |
| BE (2) | BE698567A (en, 2012) |
| BR (1) | BR6789534D0 (en, 2012) |
| CH (2) | CH484108A (en, 2012) |
| CY (1) | CY634A (en, 2012) |
| DE (4) | DE1720018B2 (en, 2012) |
| DK (2) | DK132411C (en, 2012) |
| ES (1) | ES340591A1 (en, 2012) |
| FI (2) | FI48348C (en, 2012) |
| FR (3) | FR6770M (en, 2012) |
| GB (4) | GB1154742A (en, 2012) |
| IL (2) | IL27934A (en, 2012) |
| LU (1) | LU53619A1 (en, 2012) |
| NL (3) | NL141087B (en, 2012) |
| NO (2) | NO121950B (en, 2012) |
| SE (2) | SE313564B (en, 2012) |
| YU (2) | YU32531B (en, 2012) |
Families Citing this family (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1345872A (en) * | 1970-09-03 | 1974-02-06 | Wyeth John & Brother Ltd | Amino-and acylamino-pyridine and hydropyridine derivatives |
| BE790747A (fr) * | 1971-10-30 | 1973-02-15 | Whitefin Holding Sa | Stereo-isomeres du 1-(1'-(0-chloro-benzyl)-pyrrol-2'-yl) -2-dibutyl sec.-amino-ethanol et procede pour leur preparation |
| JPS5549575B2 (en, 2012) * | 1971-10-30 | 1980-12-12 | ||
| US3972925A (en) * | 1974-10-29 | 1976-08-03 | Eli Lilly And Company | N-perfluoroacyl-amino acids and derivatives thereof |
| US4029672A (en) * | 1976-02-26 | 1977-06-14 | American Hoechst Corporation | Aminoalkylpyrrolobenzoxazalkanes |
| DE2615117B2 (de) * | 1976-04-07 | 1978-07-20 | Siemens Ag, 1000 Berlin Und 8000 Muenchen | Mit einer Überspannungsschutzanordnung versehener konstantspannungsgeregelter bürstenloser Synchrongenerator |
| BE848465A (fr) | 1976-11-18 | 1977-03-16 | Stereo-isomeres de 1-(1'-benzyl-2' pyrryl)-2-disec.butylaminoethanols a activite analgesique et preparations pharmaceutiques qui les contiennent | |
| US4560770A (en) * | 1983-02-09 | 1985-12-24 | Ciba-Geigy Corporation | Pesticidal compositions based on N-pyrrolylphenyl-N'-benzoylurea compounds |
| US4667039A (en) * | 1983-11-07 | 1987-05-19 | Hoechst-Roussel Pharmaceuticals Inc. | 11-substituted 5H,11H-pyrrolo(2,1-C) (1,4)benzoxazepines as antipsychotic and analgesic agents |
| US5360811A (en) * | 1990-03-13 | 1994-11-01 | Hoechst-Roussel Pharmaceuticals Incorporated | 1-alkyl-, 1-alkenyl-, and 1-alkynylaryl-2-amino-1,3-propanediols and related compounds as anti-inflammatory agents |
| DE4020851A1 (de) * | 1990-06-29 | 1992-01-02 | Cassella Ag | 2-(aminoalkyl)-pyrrolaldehyde, verfahren zu ihrer herstellung und ihre verwendung |
| EP1488418A1 (de) * | 2002-03-19 | 2004-12-22 | Bayer Chemicals AG | Squaryliumfarbstoffe als lichtabsorbierende verbindung in der informationschicht von optischen datenträgern |
| GB0711776D0 (en) * | 2007-06-18 | 2007-07-25 | Syngenta Participations Ag | Substituted aromatic heterocyclic compounds as fungicides |
| WO2020006269A1 (en) * | 2018-06-27 | 2020-01-02 | Proteostasis Therapeutics, Inc. | Proteasome activity enhancing compounds |
| SG11202013026WA (en) | 2018-06-27 | 2021-01-28 | Proteostasis Therapeutics Inc | Proteasome activity enhancing compounds |
-
1966
- 1966-05-17 GB GB21777/66A patent/GB1154742A/en not_active Expired
- 1966-05-17 GB GB21779/66A patent/GB1154744A/en not_active Expired
- 1966-05-17 GB GB21778/66A patent/GB1154743A/en not_active Expired
- 1966-05-17 GB GB53844/68A patent/GB1154745A/en not_active Expired
-
1967
- 1967-05-08 IL IL27934A patent/IL27934A/xx unknown
- 1967-05-08 IL IL27933A patent/IL27933A/en unknown
- 1967-05-08 LU LU53619D patent/LU53619A1/xx unknown
- 1967-05-08 US US636625A patent/US3558652A/en not_active Expired - Lifetime
- 1967-05-08 US US636649A patent/US3539589A/en not_active Expired - Lifetime
- 1967-05-11 DE DE19671720018 patent/DE1720018B2/de active Granted
- 1967-05-12 NO NO168123A patent/NO121950B/no unknown
- 1967-05-12 DE DE1795841A patent/DE1795841C3/de not_active Expired
- 1967-05-12 AT AT448267A patent/AT278770B/de not_active IP Right Cessation
- 1967-05-12 DE DE1720020A patent/DE1720020B2/de active Granted
- 1967-05-12 DE DE1720019A patent/DE1720019C3/de not_active Expired
- 1967-05-12 NO NO168124A patent/NO123034B/no unknown
- 1967-05-16 DK DK254867A patent/DK132411C/da active
- 1967-05-16 YU YU0973/67A patent/YU32531B/xx unknown
- 1967-05-16 DK DK254767AA patent/DK133943B/da unknown
- 1967-05-16 ES ES340591A patent/ES340591A1/es not_active Expired
- 1967-05-17 CH CH694267A patent/CH484108A/de not_active IP Right Cessation
- 1967-05-17 FI FI671407A patent/FI48348C/fi active
- 1967-05-17 FR FR106670A patent/FR6770M/fr not_active Expired
- 1967-05-17 FR FR106668A patent/FR6663M/fr not_active Expired
- 1967-05-17 BE BE698567D patent/BE698567A/xx unknown
- 1967-05-17 NL NL676706839A patent/NL141087B/xx not_active IP Right Cessation
- 1967-05-17 FR FR106669A patent/FR6769M/fr not_active Expired
- 1967-05-17 SE SE6866/67A patent/SE313564B/xx unknown
- 1967-05-17 SE SE6867/67A patent/SE313565B/xx unknown
- 1967-05-17 BE BE698568D patent/BE698568A/xx unknown
- 1967-05-17 NL NL676706841A patent/NL149375B/xx not_active IP Right Cessation
- 1967-05-17 NL NL6706840.A patent/NL156394B/xx not_active IP Right Cessation
- 1967-05-17 FI FI671408A patent/FI48349C/fi active
- 1967-05-17 BR BR189534/67A patent/BR6789534D0/pt unknown
- 1967-05-17 CH CH694067A patent/CH484107A/de not_active IP Right Cessation
-
1970
- 1970-10-05 US US78262A patent/US3706750A/en not_active Expired - Lifetime
-
1972
- 1972-02-23 CY CY63472A patent/CY634A/xx unknown
-
1973
- 1973-09-04 YU YU2345/73A patent/YU36700B/xx unknown
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