GB1317125A - Piperazine compositions and method of treatment - Google Patents

Piperazine compositions and method of treatment

Info

Publication number
GB1317125A
GB1317125A GB1798771A GB1798771A GB1317125A GB 1317125 A GB1317125 A GB 1317125A GB 1798771 A GB1798771 A GB 1798771A GB 1798771 A GB1798771 A GB 1798771A GB 1317125 A GB1317125 A GB 1317125A
Authority
GB
United Kingdom
Prior art keywords
alkyl
hydrogen
piperazine
treatment
compositions
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB1798771A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Gruppo Lepetit SpA
Original Assignee
Gruppo Lepetit SpA
Lepetit SpA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from IT25380/70A external-priority patent/IT1037016B/en
Priority claimed from IT2015171A external-priority patent/IT1044924B/en
Application filed by Gruppo Lepetit SpA, Lepetit SpA filed Critical Gruppo Lepetit SpA
Publication of GB1317125A publication Critical patent/GB1317125A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/22—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with hetero atoms directly attached to ring nitrogen atoms
    • C07D295/28—Nitrogen atoms
    • C07D295/30—Nitrogen atoms non-acylated
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/08—Bridged systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)

Abstract

1317125 Therapeutic piperazine compositions GROPPO LEPETIT SpA 28 May 1971 [1 June 1970 3 Feb 1971] 17987/71 Heading A5B [Also in Division C2] Pharmaceutical compositions of a piperazine compound of the formula I wherein X is H 2 , benzylidene or a group (H, acyl) where acyl is a C 2-6 aliphatic carbonyl group; R is C 2-6 alkyl, phenyl-C 1-6 -alkyl or C 2-6 aliphatic carbonyl or when X is other than H 2 , also hydrogen or methyl; R<SP>1</SP>, R<SP>2</SP>, R<SP>3</SP> and R<SP>4</SP> each are hydrogen or C 1-6 alkyl, with the proviso that when R is benzyl at least one of the radicals R<SP>1</SP>, R<SP>2</SP>, R<SP>3</SP> and R<SP>4</SP> is not hydrogen, or each of the pairs R<SP>1</SP> and R<SP>2</SP> or R<SP>3</SP> and R<SP>4</SP> are a C 2-6 alkylidene radical bridging the piperazine ring or a pharmaceutically acceptable acid addition salt thereof with the usual excipients are useful for the treatment of virus diseases.
GB1798771A 1970-06-01 1971-05-28 Piperazine compositions and method of treatment Expired GB1317125A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IT25380/70A IT1037016B (en) 1970-06-01 1970-06-01 ANTIVIRAL COMPOSITIONS CONTAINING DERIVATIVES OF PIPERAZIN
IT2015171A IT1044924B (en) 1971-02-03 1971-02-03 Antiviral piperazine deriv compns contg 1 amino (or acylamino - or benzylideneamino) piperazine derivs

Publications (1)

Publication Number Publication Date
GB1317125A true GB1317125A (en) 1973-05-16

Family

ID=26327416

Family Applications (1)

Application Number Title Priority Date Filing Date
GB1798771A Expired GB1317125A (en) 1970-06-01 1971-05-28 Piperazine compositions and method of treatment

Country Status (7)

Country Link
JP (2) JPS4924212B1 (en)
BE (1) BE767846A (en)
DE (1) DE2127171A1 (en)
FR (1) FR2100709B1 (en)
GB (1) GB1317125A (en)
IL (1) IL36616A (en)
NL (1) NL7105342A (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1146790A4 (en) * 1999-01-25 2004-03-17 Smithkline Beecham Corp Compounds and methods

Also Published As

Publication number Publication date
BE767846A (en) 1971-10-18
FR2100709B1 (en) 1975-10-10
FR2100709A1 (en) 1972-03-24
IL36616A (en) 1975-02-10
IL36616A0 (en) 1971-06-23
DE2127171A1 (en) 1971-12-09
JPS5025577A (en) 1975-03-18
JPS4924212B1 (en) 1974-06-21
NL7105342A (en) 1971-12-03

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Legal Events

Date Code Title Description
PS Patent sealed [section 19, patents act 1949]
PLNP Patent lapsed through nonpayment of renewal fees