GB1022033A - Basic esters - Google Patents
Basic estersInfo
- Publication number
- GB1022033A GB1022033A GB32350/65A GB3235065A GB1022033A GB 1022033 A GB1022033 A GB 1022033A GB 32350/65 A GB32350/65 A GB 32350/65A GB 3235065 A GB3235065 A GB 3235065A GB 1022033 A GB1022033 A GB 1022033A
- Authority
- GB
- United Kingdom
- Prior art keywords
- groups
- basic esters
- antispasmodics
- vasodilators
- piperidino
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 150000002148 esters Chemical class 0.000 title abstract 2
- 239000002253 acid Substances 0.000 abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 2
- CPEONABTMRSIKA-UHFFFAOYSA-N 1,4$l^{2}-oxazinane Chemical compound C1COCC[N]1 CPEONABTMRSIKA-UHFFFAOYSA-N 0.000 abstract 1
- 125000000022 2-aminoethyl group Chemical group [H]C([*])([H])C([H])([H])N([H])[H] 0.000 abstract 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 230000002921 anti-spasmodic effect Effects 0.000 abstract 1
- 229940124575 antispasmodic agent Drugs 0.000 abstract 1
- 239000002775 capsule Substances 0.000 abstract 1
- 239000012458 free base Substances 0.000 abstract 1
- 229910052736 halogen Inorganic materials 0.000 abstract 1
- 125000005843 halogen group Chemical group 0.000 abstract 1
- 238000002347 injection Methods 0.000 abstract 1
- 239000007924 injection Substances 0.000 abstract 1
- 229960005015 local anesthetics Drugs 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 125000000587 piperidin-1-yl group Chemical group [H]C1([H])N(*)C([H])([H])C([H])([H])C([H])([H])C1([H])[H] 0.000 abstract 1
- 125000004368 propenyl group Chemical group C(=CC)* 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 239000000243 solution Substances 0.000 abstract 1
- 239000000829 suppository Substances 0.000 abstract 1
- 239000003826 tablet Substances 0.000 abstract 1
- -1 tetrahydrofurfuryl Chemical group 0.000 abstract 1
- 229940124549 vasodilator Drugs 0.000 abstract 1
- 239000003071 vasodilator agent Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/08—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
- C07D295/084—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
- C07D295/088—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
- C07D307/04—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
- C07D307/10—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D307/12—Radicals substituted by oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
- C07D307/04—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
- C07D307/10—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D307/16—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Hydrogenated Pyridines (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR929519A FR1363948A (fr) | 1963-03-28 | 1963-03-28 | Nouvelles bases azotées substituées par au moins un radical naphtyle ou naphtylméthyle |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1022033A true GB1022033A (en) | 1966-03-09 |
Family
ID=8800292
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB12259/64A Expired GB1022032A (en) | 1963-03-28 | 1964-03-23 | Basic ethers |
| GB32352/65A Expired GB1022034A (en) | 1963-03-28 | 1964-03-23 | New alcohols and process for producing the same |
| GB32350/65A Expired GB1022033A (en) | 1963-03-28 | 1964-03-23 | Basic esters |
Family Applications Before (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB12259/64A Expired GB1022032A (en) | 1963-03-28 | 1964-03-23 | Basic ethers |
| GB32352/65A Expired GB1022034A (en) | 1963-03-28 | 1964-03-23 | New alcohols and process for producing the same |
Country Status (13)
| Country | Link |
|---|---|
| US (1) | US3334096A (enExample) |
| AT (2) | AT247309B (enExample) |
| BE (1) | BE645366A (enExample) |
| BR (1) | BR6457920D0 (enExample) |
| CH (1) | CH483395A (enExample) |
| DE (2) | DE1543741C3 (enExample) |
| DK (2) | DK125702B (enExample) |
| ES (1) | ES298057A1 (enExample) |
| FR (1) | FR1363948A (enExample) |
| GB (3) | GB1022032A (enExample) |
| NL (5) | NL142872B (enExample) |
| NO (1) | NO117982B (enExample) |
| SE (2) | SE306747B (enExample) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4983756A (en) * | 1988-02-24 | 1991-01-08 | Nitto Boseki Co., Ltd. | Novel choline derivative and method for detemining serum cholinesterase activity using the same |
Families Citing this family (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3458529A (en) * | 1964-06-10 | 1969-07-29 | Lipha | Nitrogenous bases substituted by at least one naphthyl or naphthylmethyl radical |
| FR5671M (enExample) * | 1965-04-23 | 1968-01-02 | ||
| US4048330A (en) * | 1967-01-13 | 1977-09-13 | Syntex Corporation | Compositions containing 2-(6'-substituted-2'-naphthyl)acetic acid esters used for treating inflammation, pain or pyrexia |
| US3896157A (en) * | 1967-01-13 | 1975-07-22 | Syntex Corp | Dihydo 2-naphthylacetic acid derivatives |
| FR2146981B1 (enExample) * | 1971-07-29 | 1974-09-06 | Lipha | |
| US3973033A (en) * | 1971-07-29 | 1976-08-03 | Lipha, Lyonnaise Industrielle Pharmaceutique | Compositions and methods for producing a vasodilatory effect with a naphthyl tetrahydrofurfuryl amino-ester |
| US3975390A (en) * | 1973-07-26 | 1976-08-17 | Richter Gedeon Vegyeszeti Gyar Rt. | N-methyl substituted piperazino nitrobenzophenones and a process for the preparation thereof |
| FR2371197A1 (fr) * | 1976-11-18 | 1978-06-16 | Bottu | Nouveaux derives de l'acide isobutyrique disubstitue ainsi que leur application comme medicaments |
| FR2377196A1 (fr) * | 1977-01-13 | 1978-08-11 | Lipha | Composition medicamenteuse a usage oral |
| HU177876B (en) * | 1979-04-24 | 1982-01-28 | Nitrokemia Ipartelepek | Process for preparing 2,6-dialkyl-n-/alkoxy-methyl/-chloro-acetanilide derivatives |
| FR2505836A1 (fr) * | 1981-05-14 | 1982-11-19 | Sanofi Sa | Citrate de naftidrofuryl et son application therapeutique |
| FR2580502B1 (fr) * | 1985-04-23 | 1988-07-08 | Lipha | Emploi du " naftidrofuryl " dans la preparation d'un medicament |
| RS20050106A (sr) | 2002-08-19 | 2007-11-15 | Pfizer Products Inc., | Kombinovana terapija hiperproliferativnih bolesti |
| US20050037063A1 (en) * | 2003-07-21 | 2005-02-17 | Bolton Anthony E. | Combined therapies |
| US20060063803A1 (en) * | 2004-09-23 | 2006-03-23 | Pfizer Inc | 4-Amino substituted-2-substituted-1,2,3,4-tetrahydroquinoline compounds |
| US7741317B2 (en) | 2005-10-21 | 2010-06-22 | Bristol-Myers Squibb Company | LXR modulators |
| US7888376B2 (en) | 2005-11-23 | 2011-02-15 | Bristol-Myers Squibb Company | Heterocyclic CETP inhibitors |
| ATE547394T1 (de) | 2006-12-01 | 2012-03-15 | Bristol Myers Squibb Co | N-((3-benzyl)-2,2-(bis-phenyl)-propan-1- aminderivate als cetp-hemmer für die behandlung von atherosklerose und herz-kreislauf- erkrankungen |
| MX2015014666A (es) | 2013-04-17 | 2016-03-01 | Pfizer | Derivados de n-piperidin-3-ilbenzamida para tratar enfermedades cardiovasculares. |
| WO2016055901A1 (en) | 2014-10-08 | 2016-04-14 | Pfizer Inc. | Substituted amide compounds |
| DK3911648T3 (da) | 2019-01-18 | 2025-01-13 | Astrazeneca Ab | 6'-[[(1s,3s)-3-[[5-(difluormethoxy)-2-pyrimidinyl]amino]cyclopentyl]amino][1(2h),3'-bipyridin]-2-on som pcsk9-hæmmer og fremgangsmåder til anvendelse deraf |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2417208A (en) * | 1943-08-04 | 1947-03-11 | Geigy Ag J R | Basic esters of monoalkyl isobutyl acetic acids |
| CH396872A (de) * | 1959-08-13 | 1965-08-15 | Ciba Geigy | Verfahren zur Herstellung neuer Harnstoffe |
| US3242174A (en) * | 1962-02-06 | 1966-03-22 | Pfizer & Co C | 1-(tertiary aminosulfonyl)-3-(hydrocarbon) ureas |
-
0
- NL NL142872D patent/NL142872C/xx active
-
1963
- 1963-03-28 FR FR929519A patent/FR1363948A/fr not_active Expired
-
1964
- 1964-03-16 SE SE3234/64A patent/SE306747B/xx unknown
- 1964-03-16 SE SE11642/66A patent/SE335351B/xx unknown
- 1964-03-18 US US352963A patent/US3334096A/en not_active Expired - Lifetime
- 1964-03-18 BE BE645366D patent/BE645366A/xx unknown
- 1964-03-23 GB GB12259/64A patent/GB1022032A/en not_active Expired
- 1964-03-23 GB GB32352/65A patent/GB1022034A/en not_active Expired
- 1964-03-23 GB GB32350/65A patent/GB1022033A/en not_active Expired
- 1964-03-24 DE DE1543741A patent/DE1543741C3/de not_active Expired
- 1964-03-24 DE DE1493920A patent/DE1493920C3/de not_active Expired
- 1964-03-25 BR BR157920/64A patent/BR6457920D0/pt unknown
- 1964-03-25 AT AT778864A patent/AT247309B/de active
- 1964-03-25 AT AT260964A patent/AT250339B/de active
- 1964-03-25 DK DK152064AA patent/DK125702B/da unknown
- 1964-03-25 CH CH394364A patent/CH483395A/fr not_active IP Right Cessation
- 1964-03-26 ES ES298057A patent/ES298057A1/es not_active Expired
- 1964-03-26 NL NL646403315A patent/NL142872B/xx not_active IP Right Cessation
-
1965
- 1965-07-20 NO NO65159024A patent/NO117982B/no unknown
-
1966
- 1966-06-24 DK DK325466AA patent/DK118773B/da unknown
-
1974
- 1974-01-22 NL NL7400838A patent/NL7400838A/xx unknown
- 1974-01-22 NL NL7400837A patent/NL7400837A/xx unknown
- 1974-01-22 NL NL7400839A patent/NL7400839A/xx unknown
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4983756A (en) * | 1988-02-24 | 1991-01-08 | Nitto Boseki Co., Ltd. | Novel choline derivative and method for detemining serum cholinesterase activity using the same |
Also Published As
| Publication number | Publication date |
|---|---|
| NO117982B (enExample) | 1969-10-20 |
| DE1543741A1 (de) | 1969-12-11 |
| DK118773B (da) | 1970-10-05 |
| BR6457920D0 (pt) | 1973-02-22 |
| NL6403315A (enExample) | 1964-09-29 |
| CH483395A (fr) | 1969-12-31 |
| GB1022034A (en) | 1966-03-09 |
| GB1022032A (en) | 1966-03-09 |
| NL7400839A (enExample) | 1974-04-25 |
| DE1543741B2 (de) | 1973-07-05 |
| SE306747B (enExample) | 1968-12-09 |
| NL142872B (nl) | 1974-08-15 |
| DE1493920C3 (de) | 1974-01-17 |
| NL7400838A (enExample) | 1974-04-25 |
| DK125702B (da) | 1973-03-26 |
| BE645366A (enExample) | 1964-09-18 |
| US3334096A (en) | 1967-08-01 |
| SE335351B (enExample) | 1971-05-24 |
| ES298057A1 (es) | 1964-06-01 |
| NL7400837A (enExample) | 1974-04-25 |
| DE1493920B2 (de) | 1973-06-20 |
| NL142872C (enExample) | |
| AT250339B (de) | 1966-11-10 |
| DE1493920A1 (de) | 1969-07-10 |
| DE1543741C3 (de) | 1974-02-07 |
| AT247309B (de) | 1966-06-10 |
| FR1363948A (fr) | 1964-06-19 |
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