GB0416699D0 - Prion protein ligands and methods of use - Google Patents

Prion protein ligands and methods of use

Info

Publication number
GB0416699D0
GB0416699D0 GBGB0416699.7A GB0416699A GB0416699D0 GB 0416699 D0 GB0416699 D0 GB 0416699D0 GB 0416699 A GB0416699 A GB 0416699A GB 0416699 D0 GB0416699 D0 GB 0416699D0
Authority
GB
United Kingdom
Prior art keywords
methods
prion protein
protein ligands
ligands
prion
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
GBGB0416699.7A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Prometic Bioseparations Ltd
Original Assignee
Prometic Biosciences Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Prometic Biosciences Ltd filed Critical Prometic Biosciences Ltd
Priority to GBGB0416699.7A priority Critical patent/GB0416699D0/en
Publication of GB0416699D0 publication Critical patent/GB0416699D0/en
Priority to US11/572,787 priority patent/US8030484B2/en
Priority to CN200580031622XA priority patent/CN101023066B/zh
Priority to PT05762896T priority patent/PT1786788E/pt
Priority to ES05762896T priority patent/ES2384573T3/es
Priority to JP2007523149A priority patent/JP5201988B2/ja
Priority to BRPI0513823-0A priority patent/BRPI0513823A/pt
Priority to CA2575214A priority patent/CA2575214C/en
Priority to AP2007003897A priority patent/AP2007003897A0/xx
Priority to EA200700161A priority patent/EA014365B1/ru
Priority to EP05762896A priority patent/EP1786788B1/en
Priority to DK05762896.8T priority patent/DK1786788T3/da
Priority to AU2005266208A priority patent/AU2005266208B2/en
Priority to PCT/GB2005/002910 priority patent/WO2006010915A1/en
Priority to NZ552755A priority patent/NZ552755A/en
Priority to MX2007001103A priority patent/MX2007001103A/es
Priority to KR1020077004366A priority patent/KR20070051285A/ko
Priority to AT05762896T priority patent/ATE557011T1/de
Priority to ZA200700526A priority patent/ZA200700526B/xx
Priority to IL180787A priority patent/IL180787A/en
Priority to TNP2007000019A priority patent/TNSN07019A1/en
Priority to MA29707A priority patent/MA28820B1/fr
Priority to NO20071087A priority patent/NO338345B1/no
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D251/00—Heterocyclic compounds containing 1,3,5-triazine rings
    • C07D251/02—Heterocyclic compounds containing 1,3,5-triazine rings not condensed with other rings
    • C07D251/12—Heterocyclic compounds containing 1,3,5-triazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
    • C07D251/26—Heterocyclic compounds containing 1,3,5-triazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with only hetero atoms directly attached to ring carbon atoms
    • C07D251/40—Nitrogen atoms
    • C07D251/54—Three nitrogen atoms
    • C07D251/70—Other substituted melamines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/53—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with three nitrogens as the only ring hetero atoms, e.g. chlorazanil, melamine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/22—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof comprising organic material
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/281—Sorbents specially adapted for preparative, analytical or investigative chromatography
    • B01J20/286—Phases chemically bonded to a substrate, e.g. to silica or to polymers
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/30—Processes for preparing, regenerating, or reactivating
    • B01J20/32—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating
    • B01J20/3202—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating characterised by the carrier, support or substrate used for impregnation or coating
    • B01J20/3204—Inorganic carriers, supports or substrates
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/30—Processes for preparing, regenerating, or reactivating
    • B01J20/32—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating
    • B01J20/3202—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating characterised by the carrier, support or substrate used for impregnation or coating
    • B01J20/3206—Organic carriers, supports or substrates
    • B01J20/3208—Polymeric carriers, supports or substrates
    • B01J20/321—Polymeric carriers, supports or substrates consisting of a polymer obtained by reactions involving only carbon to carbon unsaturated bonds
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/30—Processes for preparing, regenerating, or reactivating
    • B01J20/32—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating
    • B01J20/3202—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating characterised by the carrier, support or substrate used for impregnation or coating
    • B01J20/3206—Organic carriers, supports or substrates
    • B01J20/3208—Polymeric carriers, supports or substrates
    • B01J20/3212—Polymeric carriers, supports or substrates consisting of a polymer obtained by reactions otherwise than involving only carbon to carbon unsaturated bonds
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/30—Processes for preparing, regenerating, or reactivating
    • B01J20/32—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating
    • B01J20/3214—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating characterised by the method for obtaining this coating or impregnating
    • B01J20/3217—Resulting in a chemical bond between the coating or impregnating layer and the carrier, support or substrate, e.g. a covalent bond
    • B01J20/3219—Resulting in a chemical bond between the coating or impregnating layer and the carrier, support or substrate, e.g. a covalent bond involving a particular spacer or linking group, e.g. for attaching an active group
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/30—Processes for preparing, regenerating, or reactivating
    • B01J20/32—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating
    • B01J20/3231—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating characterised by the coating or impregnating layer
    • B01J20/3242—Layers with a functional group, e.g. an affinity material, a ligand, a reactant or a complexing group
    • B01J20/3244—Non-macromolecular compounds
    • B01J20/3246—Non-macromolecular compounds having a well defined chemical structure
    • B01J20/3248—Non-macromolecular compounds having a well defined chemical structure the functional group or the linking, spacer or anchoring group as a whole comprising at least one type of heteroatom selected from a nitrogen, oxygen or sulfur, these atoms not being part of the carrier as such
    • B01J20/3251—Non-macromolecular compounds having a well defined chemical structure the functional group or the linking, spacer or anchoring group as a whole comprising at least one type of heteroatom selected from a nitrogen, oxygen or sulfur, these atoms not being part of the carrier as such comprising at least two different types of heteroatoms selected from nitrogen, oxygen or sulphur
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/30—Processes for preparing, regenerating, or reactivating
    • B01J20/32—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating
    • B01J20/3231—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating characterised by the coating or impregnating layer
    • B01J20/3242—Layers with a functional group, e.g. an affinity material, a ligand, a reactant or a complexing group
    • B01J20/3244—Non-macromolecular compounds
    • B01J20/3246—Non-macromolecular compounds having a well defined chemical structure
    • B01J20/3248—Non-macromolecular compounds having a well defined chemical structure the functional group or the linking, spacer or anchoring group as a whole comprising at least one type of heteroatom selected from a nitrogen, oxygen or sulfur, these atoms not being part of the carrier as such
    • B01J20/3255—Non-macromolecular compounds having a well defined chemical structure the functional group or the linking, spacer or anchoring group as a whole comprising at least one type of heteroatom selected from a nitrogen, oxygen or sulfur, these atoms not being part of the carrier as such comprising a cyclic structure containing at least one of the heteroatoms nitrogen, oxygen or sulfur, e.g. heterocyclic or heteroaromatic structures
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2220/00—Aspects relating to sorbent materials
    • B01J2220/50—Aspects relating to the use of sorbent or filter aid materials
    • B01J2220/54—Sorbents specially adapted for analytical or investigative chromatography
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00—Indexing scheme relating to specific properties of organic compounds
    • C07B2200/11—Compounds covalently bound to a solid support
    • C—CHEMISTRY; METALLURGY
    • C40—COMBINATORIAL TECHNOLOGY
    • C40B—COMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
    • C40B40/00—Libraries per se, e.g. arrays, mixtures
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/28—Neurological disorders
    • G01N2800/2814—Dementia; Cognitive disorders
    • G01N2800/2828—Prion diseases

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Analytical Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Inorganic Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Neurology (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Virology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Peptides Or Proteins (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • General Preparation And Processing Of Foods (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
GBGB0416699.7A 2004-07-27 2004-07-27 Prion protein ligands and methods of use Ceased GB0416699D0 (en)

Priority Applications (23)

Application Number Priority Date Filing Date Title
GBGB0416699.7A GB0416699D0 (en) 2004-07-27 2004-07-27 Prion protein ligands and methods of use
AT05762896T ATE557011T1 (de) 2004-07-27 2005-07-25 Substituierte triazine als prionproteinliganden und deren verwendung zum nachweis oder zum entfernen von prionen
EP05762896A EP1786788B1 (en) 2004-07-27 2005-07-25 Substituted triazines as prion protein ligands and their use to detect or remove prions
AU2005266208A AU2005266208B2 (en) 2004-07-27 2005-07-25 Substituted triazines as prion protein ligands and their use to detect or remove prions
PT05762896T PT1786788E (pt) 2004-07-27 2005-07-25 Triazinas substituídas como ligandos de proteína priónica e o seu uso para detetar ou remover priões
ES05762896T ES2384573T3 (es) 2004-07-27 2005-07-25 Triazinas sustituidas como ligandos de proteínas priónicas y su uso para detectar o eliminar priones
JP2007523149A JP5201988B2 (ja) 2004-07-27 2005-07-25 プリオン蛋白質リガンドとしての置換トリアジン、及び、プリオンを検出又は除去するための該置換トリアジンの使用
BRPI0513823-0A BRPI0513823A (pt) 2004-07-27 2005-07-25 triazinas substituìdas como ligantes de proteìna prion e seus usos para detectar ou remover prions
CA2575214A CA2575214C (en) 2004-07-27 2005-07-25 Substituted triazines as prion protein ligands and their use to detect or remove prions
AP2007003897A AP2007003897A0 (en) 2004-07-27 2005-07-25 Substituted triazines as prion protein ligands andtheir use to detect or remove prions
EA200700161A EA014365B1 (ru) 2004-07-27 2005-07-25 Замещённые триазины в качестве лигандов белка приона и их применение для обнаружения или удаления прионов
US11/572,787 US8030484B2 (en) 2004-07-27 2005-07-25 Substituted triazines as prion protein ligands and their use to detect or remove prions
DK05762896.8T DK1786788T3 (da) 2004-07-27 2005-07-25 Substituerede triaziner som prionproteinligander og deres anvendelse til påvisning eller fjernelse af prioner
CN200580031622XA CN101023066B (zh) 2004-07-27 2005-07-25 作为朊病毒蛋白配体的被取代的三嗪及其检测和去除朊病毒的应用
PCT/GB2005/002910 WO2006010915A1 (en) 2004-07-27 2005-07-25 Substituted triazines as prion protein ligands and their use to detect or remove prions
NZ552755A NZ552755A (en) 2004-07-27 2005-07-25 Substituted triazines as prion protein ligands and their use to detect or remove prions
MX2007001103A MX2007001103A (es) 2004-07-27 2005-07-25 Triazinas sustituidas como ligandos de proteinas prion y su uso para detectar o retirar priones.
KR1020077004366A KR20070051285A (ko) 2004-07-27 2005-07-25 프리온 단백질 리간드로써 치환된 트리아진 및 프리온을탐지 또는 제거하는 그의 용도
IL180787A IL180787A (en) 2004-07-27 2007-01-18 Triazanes are conserved as fertility protein ligands and used to identify or remove prions
ZA200700526A ZA200700526B (en) 2004-07-27 2007-01-18 Substituted triazines as prion protein ligands and their use to detect or remove prions
TNP2007000019A TNSN07019A1 (en) 2004-07-27 2007-01-19 Substituted triazines as prion protein ligands and their use to detect or remove prions
MA29707A MA28820B1 (fr) 2004-07-27 2007-02-22 Triazines substitues utilises comme ligands des proteines prions, et leur utilisation pour la detection ou l'extraction des prions
NO20071087A NO338345B1 (no) 2004-07-27 2007-02-26 Substituerte triaziner som prion protein ligander og deres anvendelse for å detektere eller fjerne prioner.

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GBGB0416699.7A GB0416699D0 (en) 2004-07-27 2004-07-27 Prion protein ligands and methods of use

Publications (1)

Publication Number Publication Date
GB0416699D0 true GB0416699D0 (en) 2004-09-01

Family

ID=32947488

Family Applications (1)

Application Number Title Priority Date Filing Date
GBGB0416699.7A Ceased GB0416699D0 (en) 2004-07-27 2004-07-27 Prion protein ligands and methods of use

Country Status (23)

Country Link
US (1) US8030484B2 (US08030484-20111004-C00003.png)
EP (1) EP1786788B1 (US08030484-20111004-C00003.png)
JP (1) JP5201988B2 (US08030484-20111004-C00003.png)
KR (1) KR20070051285A (US08030484-20111004-C00003.png)
CN (1) CN101023066B (US08030484-20111004-C00003.png)
AP (1) AP2007003897A0 (US08030484-20111004-C00003.png)
AT (1) ATE557011T1 (US08030484-20111004-C00003.png)
AU (1) AU2005266208B2 (US08030484-20111004-C00003.png)
BR (1) BRPI0513823A (US08030484-20111004-C00003.png)
CA (1) CA2575214C (US08030484-20111004-C00003.png)
DK (1) DK1786788T3 (US08030484-20111004-C00003.png)
EA (1) EA014365B1 (US08030484-20111004-C00003.png)
ES (1) ES2384573T3 (US08030484-20111004-C00003.png)
GB (1) GB0416699D0 (US08030484-20111004-C00003.png)
IL (1) IL180787A (US08030484-20111004-C00003.png)
MA (1) MA28820B1 (US08030484-20111004-C00003.png)
MX (1) MX2007001103A (US08030484-20111004-C00003.png)
NO (1) NO338345B1 (US08030484-20111004-C00003.png)
NZ (1) NZ552755A (US08030484-20111004-C00003.png)
PT (1) PT1786788E (US08030484-20111004-C00003.png)
TN (1) TNSN07019A1 (US08030484-20111004-C00003.png)
WO (1) WO2006010915A1 (US08030484-20111004-C00003.png)
ZA (1) ZA200700526B (US08030484-20111004-C00003.png)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MY175260A (en) * 2009-04-15 2020-06-17 Abraxis Bioscience Llc Prion free nanoparticle compositions and methods of making thereof
WO2012059932A1 (en) 2010-11-01 2012-05-10 Aurigene Discovery Technologies Limited 2, 4 -diaminopyrimidine derivatives as protein kinase inhibitors
KR101395814B1 (ko) * 2012-12-11 2014-05-16 한국화학연구원 플루오르알콕시기를 함유하는 트리아진계 반응성 자외선 안정제 및 그의 제조방법
WO2015112121A1 (en) * 2014-01-21 2015-07-30 The Board Of Trustees Of The University Of Arkansas Heparin affinity tag for use in protein purification

Family Cites Families (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB814947A (en) 1954-08-16 1959-06-17 Geigy Ag J R Improvements in and relating to plant growth influencing compositions
US3850918A (en) 1970-06-17 1974-11-26 Ciba Geigy Corp 2-amino-4,6-disalicyloyl-hydrazino-s-triazines
US4204060A (en) 1974-10-04 1980-05-20 Akzona Incorporated Novel monochloro-s-triazine derivatives
US4229537A (en) 1978-02-09 1980-10-21 New York University Preparation of trichloro-s-triazine activated supports for coupling ligands
US4261892A (en) 1978-04-12 1981-04-14 American Cyanamid Company 2,4,6-Tris-(substituted-amino)-s-triazines
GB8911287D0 (en) 1989-05-17 1989-07-05 Ciba Geigy Ag Lubricant compositions
NZ246059A (en) 1991-12-03 1995-08-28 Proteus Molecular Design Synthetic polypeptides with at least one antigenic site of a prion protein, methods of their use and manufacture, antibodies thereto, compositions and kits
AU4376093A (en) 1992-05-15 1993-12-13 Instituto Nazionale Neurologico C. Besta Soluble prion polypeptides, and methods for detecting and purifying thereof
US5283274A (en) 1992-06-19 1994-02-01 Uniroyal Chemical Company, Inc. Substituted pyrimidines and substituted triazines as rubber-to-metal adhesion promoters
US5441563A (en) * 1993-07-06 1995-08-15 Armstrong World Industries, Inc. Highly insoluble azole embossing inhibitor and the use thereof
US5834318A (en) 1995-05-10 1998-11-10 Bayer Corporation Screening of combinatorial peptide libraries for selection of peptide ligand useful in affinity purification of target proteins
GB9519197D0 (en) * 1995-09-20 1995-11-22 Affinity Chromatography Ltd Novel affinity ligands and their use
US5750361A (en) 1995-11-02 1998-05-12 The Regents Of The University Of California Formation and use of prion protein (PRP) complexes
US5874576A (en) 1995-12-19 1999-02-23 Givaudan-Roure (International) Sa Light screening agents
US5808011A (en) 1996-07-01 1998-09-15 Biopure Corporation Method for chromatographic removal of prions
ES2209108T3 (es) 1997-02-06 2004-06-16 Enfer Technology Limited Ensayo inmunologico para encefalopatias espongiformes.
DE19741607A1 (de) 1997-09-20 1999-03-25 Prionics Ag Synthetische Polypeptide zur Diagnose und Therapie von Prionerkrankungen
US6750025B1 (en) 1998-07-09 2004-06-15 V.I. Technologies, Inc. Method of detecting and isolating prion protein and variants thereof
JP4754693B2 (ja) 1999-01-22 2011-08-24 エラン ファーマシューティカルズ，インコーポレイテッド Ｖｌａ−４関連障害を処置するアシル誘導体
GB9910807D0 (en) 1999-05-10 1999-07-07 Prometic Biosciences Limited Novel detoxification agents and their use
IL152116A0 (en) 2000-04-05 2003-05-29 Vi Technologies Inc Prion-binding ligands and methods of using same
WO2002098878A1 (en) * 2001-02-08 2002-12-12 Memory Pharmaceuticals Corporation Trifluoromethylpurines as phosphodiesterase 4 inhibitors
CA2463822A1 (en) 2001-11-01 2003-05-08 Janssen Pharmaceutica N.V. Heteroaryl amines as glycogen synthase kinase 3beta inhibitors (gsk3 inhibitors)
AU2002340125A1 (en) * 2001-12-12 2003-06-23 New York University Triazine library with linkers
GB0224446D0 (en) * 2002-10-21 2002-11-27 Univ Cambridge Tech Affinity adsorbents for immunoglobulins
GB0228724D0 (en) * 2002-12-09 2003-01-15 Prometic Biosciences Ltd Multidimensinal libraries
SI1891088T1 (sl) 2005-06-10 2012-02-29 Ares Trading Sa Postopek za äśiĺ äśenje il-18 vezavnega proteina

Also Published As

Publication number Publication date
KR20070051285A (ko) 2007-05-17
NO338345B1 (no) 2016-08-08
EA014365B1 (ru) 2010-10-29
AU2005266208B2 (en) 2011-09-15
EP1786788B1 (en) 2012-05-09
JP2008508245A (ja) 2008-03-21
CA2575214C (en) 2014-05-27
IL180787A0 (en) 2007-06-03
MX2007001103A (es) 2007-08-14
US20080269224A1 (en) 2008-10-30
NZ552755A (en) 2010-09-30
ATE557011T1 (de) 2012-05-15
JP5201988B2 (ja) 2013-06-05
DK1786788T3 (da) 2012-06-18
PT1786788E (pt) 2012-05-24
MA28820B1 (fr) 2007-08-01
US8030484B2 (en) 2011-10-04
NO20071087L (no) 2007-04-23
BRPI0513823A (pt) 2008-05-20
ZA200700526B (en) 2008-09-25
ES2384573T3 (es) 2012-07-09
EA200700161A1 (ru) 2007-10-26
CN101023066B (zh) 2013-10-30
IL180787A (en) 2013-07-31
WO2006010915A1 (en) 2006-02-02
CA2575214A1 (en) 2006-02-02
AU2005266208A1 (en) 2006-02-02
CN101023066A (zh) 2007-08-22
EP1786788A1 (en) 2007-05-23
TNSN07019A1 (en) 2008-06-02
AP2007003897A0 (en) 2007-02-28

Similar Documents

Publication Publication Date Title
IL182422A0 (en) Prion protein binding materials and methods of use
HK1091894A1 (en) Prion protein binding materials and methods of use
ME02245B (me) Anti-cd38 humana antitjela i njihove upotrebe
EP1838331A4 (en) ANTIMICROBIAL PEPTIDES AND METHODS OF USE THEREOF
IL178593A (en) Specific antibodies of fcγriib and methods for their use
IL213843A0 (en) 4-aminotetracyclines and methods of use thereof
IL183458A0 (en) Anti-il-1r1 single domain antibodies and therapeutic uses
PL1877090T3 (pl) Trimeryczne białko fuzyjne OX-40-immunoglobulina i sposoby zastosowania
IL180554A0 (en) Rage fusion proteins and methods of use
AP2007003893A0 (en) Rage fusion proteins and methods of use
EP1812030A4 (en) ANTI-ANGIOGENIC PEPTIDES AND METHODS OF USE THEREOF
EP1786451A4 (en) ANTIANGIOGENIC PEPTIDES AND METHOD FOR THEIR USE
EP1877079A4 (en) ELASTIN BINDING PROTEIN LIGANDS DERIVED FROM PLANTS AND METHODS OF USE
SI2511297T1 (sl) Proti -CD38 humana protitelesa in njihova uporaba
ZA200607582B (en) Anti-parasitic compounds and methods of their use
EP1794589A4 (en) PROTEIN ARRAYS AND METHOD OF USE THEREOF
EP1942947A4 (en) FIBRONECTIN POLYPEPTIDES AND METHOD OF USE
EP1773880A4 (en) ENV POLYPEPTIDE COMPLEXES AND METHOD FOR THEIR USE
EP1960523A4 (en) MODIFIED POREN FORMING PROTEIN TOXINS AND USE THEREOF
ZA200606319B (en) Anti-CD38 human antibodies and uses therefor
EP1734983A4 (en) MODIFIED ANNEXINE PROTEINS AND METHODS FOR PREVENTING THROMBOSIS
GB0426161D0 (en) Protein isolation and purification
EP1813671A4 (en) SOLUBLE PROTEIN AND USE THEREOF
GB0416699D0 (en) Prion protein ligands and methods of use
EP1736775A4 (en) NEW LIGAND OF G PROTEIN-COUPLED RECEPTOR PROTEIN AND USE THEREOF

Legal Events

Date Code Title Description
AT Applications terminated before publication under section 16(1)