FR2906533B1 - Procede de generation d'anticorps actifs contre un antigene de resistance,anticorps obtenus par ledit procede et leurs utilisations - Google Patents

Procede de generation d'anticorps actifs contre un antigene de resistance,anticorps obtenus par ledit procede et leurs utilisations

Info

Publication number
FR2906533B1
FR2906533B1 FR0608514A FR0608514A FR2906533B1 FR 2906533 B1 FR2906533 B1 FR 2906533B1 FR 0608514 A FR0608514 A FR 0608514A FR 0608514 A FR0608514 A FR 0608514A FR 2906533 B1 FR2906533 B1 FR 2906533B1
Authority
FR
France
Prior art keywords
generating active
antibodies
antibodies against
antigen
resistance
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
FR0608514A
Other languages
English (en)
French (fr)
Other versions
FR2906533A1 (fr
Inventor
Liliane Goetsch
Alexandra Jouhanneaud
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pierre Fabre Medicament SA
Original Assignee
Pierre Fabre Medicament SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to FR0608514A priority Critical patent/FR2906533B1/fr
Application filed by Pierre Fabre Medicament SA filed Critical Pierre Fabre Medicament SA
Priority to JP2009529701A priority patent/JP5774276B2/ja
Priority to EP12159086.3A priority patent/EP2497491B1/en
Priority to MX2009003245A priority patent/MX2009003245A/es
Priority to HK09110874.1A priority patent/HK1131063B/xx
Priority to RU2009114682/10A priority patent/RU2515904C2/ru
Priority to BRPI0717246-0A2A priority patent/BRPI0717246A2/pt
Priority to KR1020097008469A priority patent/KR101504770B1/ko
Priority to US12/442,918 priority patent/US8241646B2/en
Priority to PCT/EP2007/060243 priority patent/WO2008046724A1/en
Priority to CA002663561A priority patent/CA2663561A1/en
Priority to EP07820636.4A priority patent/EP2081592B1/en
Priority to EP12159077.2A priority patent/EP2494984B1/en
Priority to NZ576420A priority patent/NZ576420A/en
Priority to CN200780035523.8A priority patent/CN101516394B/zh
Priority to EP12159083.0A priority patent/EP2491945B9/en
Priority to AU2007312437A priority patent/AU2007312437C1/en
Priority to UAA200904020A priority patent/UA102812C2/ru
Priority to TW096136193A priority patent/TWI516276B/zh
Priority to ARP070104320A priority patent/AR063061A1/es
Publication of FR2906533A1 publication Critical patent/FR2906533A1/fr
Priority to IL197790A priority patent/IL197790A/en
Priority to TN2009000102A priority patent/TN2009000102A1/fr
Priority to MA31800A priority patent/MA30954B1/fr
Priority to ZA200902697A priority patent/ZA200902697B/xx
Priority to NO20091613A priority patent/NO20091613L/no
Priority to US13/544,672 priority patent/US8808667B2/en
Application granted granted Critical
Publication of FR2906533B1 publication Critical patent/FR2906533B1/fr
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/30—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/515—Animal cells
    • A61K2039/5152—Tumor cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/545—Medicinal preparations containing antigens or antibodies characterised by the dose, timing or administration schedule
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/73—Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Cell Biology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biochemistry (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Mycology (AREA)
  • Virology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Developmental Biology & Embryology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Zoology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
FR0608514A 2006-09-28 2006-09-28 Procede de generation d'anticorps actifs contre un antigene de resistance,anticorps obtenus par ledit procede et leurs utilisations Expired - Fee Related FR2906533B1 (fr)

Priority Applications (26)

Application Number Priority Date Filing Date Title
FR0608514A FR2906533B1 (fr) 2006-09-28 2006-09-28 Procede de generation d'anticorps actifs contre un antigene de resistance,anticorps obtenus par ledit procede et leurs utilisations
EP12159083.0A EP2491945B9 (en) 2006-09-28 2007-09-27 Method for generating active antibodies against a resistance antigen, antibodies obtained by said method and their uses
MX2009003245A MX2009003245A (es) 2006-09-28 2007-09-27 Metodo para generar anticuerpos contra un antigeno resistente, anticuerpos obtenidos por el metodo y sus usos.
HK09110874.1A HK1131063B (en) 2006-09-28 2007-09-27 Method for generating active antibodies against a resistance antigen, antibodies obtained by said method and their uses
RU2009114682/10A RU2515904C2 (ru) 2006-09-28 2007-09-27 Способ генерирования активных антител к антигену устойчивости, антитела, полученные этим способом, и их применения
BRPI0717246-0A2A BRPI0717246A2 (pt) 2006-09-28 2007-09-27 Método para gerar anticorpos ativos contra um antígeno de resistência, anticorpos obtidos pelo dito método e seus usos
KR1020097008469A KR101504770B1 (ko) 2006-09-28 2007-09-27 내성 항원에 대항하는 활성 항체의 생산 방법, 상기 방법에 의해 생산된 항체 및 이의 용도
US12/442,918 US8241646B2 (en) 2006-09-28 2007-09-27 Method for generating active antibodies against a resistance antigen, antibodies obtained by said method and their uses
PCT/EP2007/060243 WO2008046724A1 (en) 2006-09-28 2007-09-27 Method for generating active antibodies against a resistance antigen, antibodies obtained by said method and their uses
CA002663561A CA2663561A1 (en) 2006-09-28 2007-09-27 Method for generating active antibodies against a resistance antigen, antibodies obtained by said method and their uses
EP07820636.4A EP2081592B1 (en) 2006-09-28 2007-09-27 Method for generating active antibodies against a resistance antigen, antibodies obtained by said method and their uses
EP12159077.2A EP2494984B1 (en) 2006-09-28 2007-09-27 Method for generating active antibodies against a resistance antigen, antibodies obtained by said method and their uses
NZ576420A NZ576420A (en) 2006-09-28 2007-09-27 Method for generating active antibodies against a resistance antigen, antibodies obtained by said method and their uses
CN200780035523.8A CN101516394B (zh) 2006-09-28 2007-09-27 制备抗耐药性抗原的活性抗体的方法、所述方法获得的抗体及其用途
JP2009529701A JP5774276B2 (ja) 2006-09-28 2007-09-27 耐性抗原に対する活性抗体を作製する方法、その方法により得られる抗体およびそれらの使用
AU2007312437A AU2007312437C1 (en) 2006-09-28 2007-09-27 Method for generating active antibodies against a resistance antigen, antibodies obtained by said method and their uses
EP12159086.3A EP2497491B1 (en) 2006-09-28 2007-09-27 Method for generating active antibodies against a resistance antigen, antibodies obtained by said method and their uses
UAA200904020A UA102812C2 (ru) 2006-09-28 2007-09-27 Способ генерирования активных антител к антигену устойчивости, антитела, полученные этим способом, и их применение
TW096136193A TWI516276B (zh) 2006-09-28 2007-09-28 產生對抗一抗性抗原之活性抗體的方法、由該方法所獲得之抗體及其用途
ARP070104320A AR063061A1 (es) 2006-09-28 2007-09-28 Metodo de generacion de anticuerpos activos contra un antigeno de resistencia, anticuerpos obtenidos por dicho metodo y sus utilizaciones
IL197790A IL197790A (en) 2006-09-28 2009-03-24 METHOD FOR PRODUCING ANTI-RESISTANT ANTI-RESISTANT ANTIBODY, ANTIBODY PRODUCED AND USED ANTIBODIES
TN2009000102A TN2009000102A1 (en) 2006-09-28 2009-03-26 Method for generating active antibodies against a resistance antigen, antibodies obtained by said method and their uses
MA31800A MA30954B1 (fr) 2006-09-28 2009-04-17 Procede de generation d'anticorps actifs contre un antigene de resistance, anticorps obtenus par ce procede et utilisations de ces anticorps
ZA200902697A ZA200902697B (en) 2006-09-28 2009-04-20 Method for generating active antibodies against a resistance antigen, antibodies obtained by said method and their uses
NO20091613A NO20091613L (no) 2006-09-28 2009-04-22 Fremgangsmate for generering av aktive antistoffer mot et resistansantigen, antistoffer fremskaffet ved nevnte fremgangsmate og deres anvendelser
US13/544,672 US8808667B2 (en) 2006-09-28 2012-07-09 Method for generating active antibodies against a resistance antigen, antibodies obtained by said method and their uses

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR0608514A FR2906533B1 (fr) 2006-09-28 2006-09-28 Procede de generation d'anticorps actifs contre un antigene de resistance,anticorps obtenus par ledit procede et leurs utilisations

Publications (2)

Publication Number Publication Date
FR2906533A1 FR2906533A1 (fr) 2008-04-04
FR2906533B1 true FR2906533B1 (fr) 2013-02-22

Family

ID=38164542

Family Applications (1)

Application Number Title Priority Date Filing Date
FR0608514A Expired - Fee Related FR2906533B1 (fr) 2006-09-28 2006-09-28 Procede de generation d'anticorps actifs contre un antigene de resistance,anticorps obtenus par ledit procede et leurs utilisations

Country Status (21)

Country Link
US (2) US8241646B2 (enExample)
EP (4) EP2491945B9 (enExample)
JP (1) JP5774276B2 (enExample)
KR (1) KR101504770B1 (enExample)
CN (1) CN101516394B (enExample)
AR (1) AR063061A1 (enExample)
AU (1) AU2007312437C1 (enExample)
BR (1) BRPI0717246A2 (enExample)
CA (1) CA2663561A1 (enExample)
FR (1) FR2906533B1 (enExample)
IL (1) IL197790A (enExample)
MA (1) MA30954B1 (enExample)
MX (1) MX2009003245A (enExample)
NO (1) NO20091613L (enExample)
NZ (1) NZ576420A (enExample)
RU (1) RU2515904C2 (enExample)
TN (1) TN2009000102A1 (enExample)
TW (1) TWI516276B (enExample)
UA (1) UA102812C2 (enExample)
WO (1) WO2008046724A1 (enExample)
ZA (1) ZA200902697B (enExample)

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US7241444B2 (en) * 2002-01-18 2007-07-10 Pierre Fabre Medicament Anti-IGF-IR antibodies and uses thereof
CU23736A1 (es) * 2009-05-04 2011-11-15 Centro Inmunologia Molecular Anticuerpos que reconocen sulfatidos y proteoglicanos sulfatados y su uso
WO2011004899A1 (en) * 2009-07-06 2011-01-13 Takeda Pharmaceutical Company Limited Cancerous disease modifying antibodies
US20120282211A1 (en) * 2009-11-24 2012-11-08 Carnegie Mellon University Antibodies and conjugates for modulators of angiogenesis
EP3165538A1 (en) 2010-11-03 2017-05-10 Argen-X Nv Anti c-met antibodies
US9255595B2 (en) * 2011-04-29 2016-02-09 Bae Systems Information And Electronic Systems Integration Inc. Optical dome bezel
EP2773660A2 (en) 2011-11-03 2014-09-10 Argen-X B.V. Chimeric human-camel antigens and their use
BR112015022123B1 (pt) * 2013-03-15 2022-08-09 Intrinsic Lifesciences, Llc Anticorpos, fragmentos de ligação ao antígeno dos mesmos que se ligam especificamente à hepcidina ou um peptídeo de hepcidina, uso, meio contentor e kit
CN106794194A (zh) * 2014-06-30 2017-05-31 中央研究院 用于癌症治疗的介白素‑17受体b（il‑17rb）及其配体il‑17b之拮抗剂
AU2015321462B2 (en) 2014-09-22 2020-04-30 Intrinsic Lifesciences Llc Humanized anti-hepcidin antibodies and uses thereof
TWI716400B (zh) * 2015-04-27 2021-01-21 法商皮爾法伯製藥公司 新穎的igf-1r抗體及其用於癌症診斷之用途（二）
AR104413A1 (es) * 2015-04-27 2017-07-19 Pf Medicament Anticuerpo de igf-1r y su utilización para diagnosticar cáncer
JP6976241B2 (ja) * 2015-08-14 2021-12-08 メルク・シャープ・アンド・ドーム・コーポレーションMerck Sharp & Dohme Corp. 抗ｔｉｇｉｔ抗体
JP6952028B2 (ja) * 2015-09-29 2021-10-20 シャンハイ チャンジアン バイオテクノロジー カンパニー リミテッド Ｐｄ−１抗体およびその使用
GB2547179A (en) * 2015-10-26 2017-08-16 Quethera Ltd Genetic construct
WO2025111382A2 (en) * 2023-11-21 2025-05-30 Board Of Regents, The University Of Texas System Anti-lamp5 antibodies, engineered immune cells expressing anti-lamp5 antibodies, and uses thereof

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Also Published As

Publication number Publication date
TW200822934A (en) 2008-06-01
EP2497491B1 (en) 2017-03-01
BRPI0717246A2 (pt) 2013-10-08
KR20090057469A (ko) 2009-06-05
AR063061A1 (es) 2008-12-23
CN101516394B (zh) 2014-07-30
KR101504770B1 (ko) 2015-03-20
IL197790A (en) 2016-10-31
JP2010504743A (ja) 2010-02-18
IL197790A0 (en) 2011-08-01
EP2491945B9 (en) 2017-03-08
US8241646B2 (en) 2012-08-14
EP2494984B1 (en) 2017-01-04
EP2491945B1 (en) 2016-12-07
FR2906533A1 (fr) 2008-04-04
AU2007312437C1 (en) 2014-04-10
US20130028835A1 (en) 2013-01-31
EP2497491A1 (en) 2012-09-12
UA102812C2 (ru) 2013-08-27
WO2008046724A1 (en) 2008-04-24
CA2663561A1 (en) 2008-04-24
EP2494984A1 (en) 2012-09-05
CN101516394A (zh) 2009-08-26
AU2007312437B2 (en) 2014-01-23
US20100146650A1 (en) 2010-06-10
NO20091613L (no) 2009-06-26
EP2081592A1 (en) 2009-07-29
US8808667B2 (en) 2014-08-19
ZA200902697B (en) 2010-04-28
MA30954B1 (fr) 2009-12-01
MX2009003245A (es) 2009-07-07
TN2009000102A1 (en) 2010-08-19
HK1131063A1 (en) 2010-01-15
RU2009114682A (ru) 2010-11-20
NZ576420A (en) 2012-05-25
JP5774276B2 (ja) 2015-09-09
AU2007312437A1 (en) 2008-04-24
EP2081592B1 (en) 2016-01-13
RU2515904C2 (ru) 2014-05-20
TWI516276B (zh) 2016-01-11
EP2491945A1 (en) 2012-08-29

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