FR2901273B1 - Inhibiteurs du virus du papillome humain et les compositions pharmaceutiques les contenant - Google Patents

Inhibiteurs du virus du papillome humain et les compositions pharmaceutiques les contenant

Info

Publication number
FR2901273B1
FR2901273B1 FR0604496A FR0604496A FR2901273B1 FR 2901273 B1 FR2901273 B1 FR 2901273B1 FR 0604496 A FR0604496 A FR 0604496A FR 0604496 A FR0604496 A FR 0604496A FR 2901273 B1 FR2901273 B1 FR 2901273B1
Authority
FR
France
Prior art keywords
inhibitors
same
pharmaceutical compositions
compositions containing
papilloma virus
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
FR0604496A
Other languages
English (en)
French (fr)
Other versions
FR2901273A1 (fr
Inventor
Marta Blumenfeld
Delphine Compere
Jean Michel Gauthier
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Anaconda Pharma SAS
Original Assignee
Anaconda Pharma SAS
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to FR0604496A priority Critical patent/FR2901273B1/fr
Application filed by Anaconda Pharma SAS filed Critical Anaconda Pharma SAS
Priority to ES07729287.8T priority patent/ES2436772T3/es
Priority to DK07729287.8T priority patent/DK2024350T3/da
Priority to PT77292878T priority patent/PT2024350E/pt
Priority to EP07729287.8A priority patent/EP2024350B1/fr
Priority to CA2652469A priority patent/CA2652469C/fr
Priority to JP2009511485A priority patent/JP5399237B2/ja
Priority to PCT/EP2007/054843 priority patent/WO2007135106A1/fr
Priority to US12/300,998 priority patent/US8207373B2/en
Priority to BRPI0711208-4A priority patent/BRPI0711208A2/pt
Priority to MX2008014771A priority patent/MX2008014771A/es
Priority to ARP070102162A priority patent/AR061027A1/es
Priority to CN2007800218616A priority patent/CN101466693B/zh
Publication of FR2901273A1 publication Critical patent/FR2901273A1/fr
Application granted granted Critical
Publication of FR2901273B1 publication Critical patent/FR2901273B1/fr
Priority to US13/466,530 priority patent/US9452991B2/en
Priority to US15/276,208 priority patent/US9974779B2/en
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445Non condensed piperidines, e.g. piperocaine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/12Keratolytics, e.g. wart or anti-corn preparations
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/20Antivirals for DNA viruses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D295/00Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/12Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms
    • C07D295/135Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms with the ring nitrogen atoms and the substituent nitrogen atoms separated by carbocyclic rings or by carbon chains interrupted by carbocyclic rings

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Virology (AREA)
  • Epidemiology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Dermatology (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Pulmonology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Plural Heterocyclic Compounds (AREA)
FR0604496A 2006-05-19 2006-05-19 Inhibiteurs du virus du papillome humain et les compositions pharmaceutiques les contenant Expired - Fee Related FR2901273B1 (fr)

Priority Applications (15)

Application Number Priority Date Filing Date Title
FR0604496A FR2901273B1 (fr) 2006-05-19 2006-05-19 Inhibiteurs du virus du papillome humain et les compositions pharmaceutiques les contenant
MX2008014771A MX2008014771A (es) 2006-05-19 2007-05-18 Derivados de piperidina como inhibidores del virus del papiloma humano.
PT77292878T PT2024350E (pt) 2006-05-19 2007-05-18 Derivados de piperidina como inibidores don vírus do papiloma humano
EP07729287.8A EP2024350B1 (fr) 2006-05-19 2007-05-18 Derives de piperidine comme inhibiteurs du virus du papillome humain
CA2652469A CA2652469C (fr) 2006-05-19 2007-05-18 Derives de piperidine comme inhibiteurs du virus du papillome humain
JP2009511485A JP5399237B2 (ja) 2006-05-19 2007-05-18 ヒトパピローマウイルス阻害剤としてのピペリジン誘導体
PCT/EP2007/054843 WO2007135106A1 (fr) 2006-05-19 2007-05-18 Derives de piperidine comme inhibiteurs du virus du papillome humain
US12/300,998 US8207373B2 (en) 2006-05-19 2007-05-18 Benzoic acid derivatives as human papilloma virus inhibitors
ES07729287.8T ES2436772T3 (es) 2006-05-19 2007-05-18 Derivados de piperidina como inhibidores del virus del papiloma humano
DK07729287.8T DK2024350T3 (da) 2006-05-19 2007-05-18 Piperidinderivater som inhibitorer af human papillomavirus
ARP070102162A AR061027A1 (es) 2006-05-19 2007-05-18 Inhibidores del virus del papiloma humano y las composiciones farmaceuticas que los contienen
CN2007800218616A CN101466693B (zh) 2006-05-19 2007-05-18 用作人乳头瘤病毒抑制剂的哌啶衍生物
BRPI0711208-4A BRPI0711208A2 (pt) 2006-05-19 2007-05-18 compostos, intermediários para a sìtemse dos compostos, processo, composição farmacêutica, uso de um composto e usos
US13/466,530 US9452991B2 (en) 2006-05-19 2012-05-08 Piperidine derivatives as human papilloma virus inhibitors
US15/276,208 US9974779B2 (en) 2006-05-19 2016-09-26 Piperidine derivatives as human papilloma virus inhibitors

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR0604496A FR2901273B1 (fr) 2006-05-19 2006-05-19 Inhibiteurs du virus du papillome humain et les compositions pharmaceutiques les contenant

Publications (2)

Publication Number Publication Date
FR2901273A1 FR2901273A1 (fr) 2007-11-23
FR2901273B1 true FR2901273B1 (fr) 2010-12-24

Family

ID=37575135

Family Applications (1)

Application Number Title Priority Date Filing Date
FR0604496A Expired - Fee Related FR2901273B1 (fr) 2006-05-19 2006-05-19 Inhibiteurs du virus du papillome humain et les compositions pharmaceutiques les contenant

Country Status (13)

Country Link
US (3) US8207373B2 (enExample)
EP (1) EP2024350B1 (enExample)
JP (1) JP5399237B2 (enExample)
CN (1) CN101466693B (enExample)
AR (1) AR061027A1 (enExample)
BR (1) BRPI0711208A2 (enExample)
CA (1) CA2652469C (enExample)
DK (1) DK2024350T3 (enExample)
ES (1) ES2436772T3 (enExample)
FR (1) FR2901273B1 (enExample)
MX (1) MX2008014771A (enExample)
PT (1) PT2024350E (enExample)
WO (1) WO2007135106A1 (enExample)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2923825B1 (fr) * 2007-11-20 2013-05-03 Anaconda Pharma Nouveaux inhibiteurs du virus du papillome humain et les compositions pharmaceutiques les contenant.
FR2990134B1 (fr) * 2012-05-07 2014-11-21 Anaconda Pharma Composition pharmaceutique d'un inhibiteur du virus du papillome
FR3000490B1 (fr) * 2012-12-27 2015-03-13 Anaconda Pharma Procede de synthese d'une hydrazine utile dans le traitement du virus du papillome
ES2796276T3 (es) * 2015-02-05 2020-11-26 Ab Science Compuestos con actividad antitumoral
WO2017009751A1 (en) 2015-07-15 2017-01-19 Pfizer Inc. Pyrimidine derivatives
CN105582083A (zh) * 2015-09-08 2016-05-18 石友爱 一种治疗鲍温样丘疹病的中药
WO2018157843A1 (zh) * 2017-03-02 2018-09-07 中国科学院上海药物研究所 2-(取代苯杂基)芳香甲酸类fto抑制剂,其制备方法及其应用
CN109748903B (zh) * 2017-11-01 2021-08-10 北京协和制药二厂 吡法齐明的制备方法
EP3594206A1 (en) 2018-07-09 2020-01-15 Abivax Phenyl-n-quinoline derivatives for treating a rna virus infection
EP3594205A1 (en) * 2018-07-09 2020-01-15 Abivax Phenyl-n-aryl derivatives for treating a rna virus infection
JP2020127293A (ja) * 2019-02-05 2020-08-20 ファナック株式会社 ロータコアの製造装置及びロータコアの製造方法、並びにロータ構造
CN110041223B (zh) * 2019-06-03 2021-10-22 西北师范大学 以肼类化合物为原料氧化合成偶氮类化合物的方法
CN114276273B (zh) * 2021-12-29 2024-06-21 维思普新材料(苏州)有限公司 一种基于四苯基肼类衍生物的有机电致发光材料及其电子器件

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4292429A (en) * 1978-03-08 1981-09-29 Ciba-Geigy Corporation Imidazole urea and amido compounds
EE200100492A (et) * 1999-03-19 2002-12-16 Vertex Pharmaceuticals Incorporated Ensüümi IMPDH inhibiitorid
JP4550811B2 (ja) * 2003-06-09 2010-09-22 ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング パピローマウイルスのインヒビター

Also Published As

Publication number Publication date
US20170079968A1 (en) 2017-03-23
US9452991B2 (en) 2016-09-27
EP2024350B1 (fr) 2013-09-18
MX2008014771A (es) 2008-11-28
AR061027A1 (es) 2008-07-30
WO2007135106A1 (fr) 2007-11-29
CA2652469A1 (fr) 2007-11-29
CA2652469C (fr) 2016-05-03
US20090209586A1 (en) 2009-08-20
US8207373B2 (en) 2012-06-26
JP2009537595A (ja) 2009-10-29
US20120220633A1 (en) 2012-08-30
FR2901273A1 (fr) 2007-11-23
EP2024350A1 (fr) 2009-02-18
US20180021318A9 (en) 2018-01-25
US9974779B2 (en) 2018-05-22
CN101466693A (zh) 2009-06-24
CN101466693B (zh) 2012-12-12
DK2024350T3 (da) 2013-12-09
BRPI0711208A2 (pt) 2011-03-22
ES2436772T3 (es) 2014-01-07
JP5399237B2 (ja) 2014-01-29
PT2024350E (pt) 2013-12-11

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