FR2804604B1 - Utilisation d'un antagoniste des recepteurs aux cannabinoides centraux pour la preparation de medicaments utiles pour faciliter l'arret de la consommation de tabac - Google Patents

Utilisation d'un antagoniste des recepteurs aux cannabinoides centraux pour la preparation de medicaments utiles pour faciliter l'arret de la consommation de tabac

Info

Publication number
FR2804604B1
FR2804604B1 FR0001682A FR0001682A FR2804604B1 FR 2804604 B1 FR2804604 B1 FR 2804604B1 FR 0001682 A FR0001682 A FR 0001682A FR 0001682 A FR0001682 A FR 0001682A FR 2804604 B1 FR2804604 B1 FR 2804604B1
Authority
FR
France
Prior art keywords
stoppage
facilitate
preparation
receptor antagonist
cannabinoid receptor
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
FR0001682A
Other languages
English (en)
French (fr)
Other versions
FR2804604A1 (fr
Inventor
Jean Charles Blanchard
Francois Menard
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sanofi Aventis France
Original Assignee
Sanofi Synthelabo SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to FR0001682A priority Critical patent/FR2804604B1/fr
Application filed by Sanofi Synthelabo SA filed Critical Sanofi Synthelabo SA
Priority to PL358221A priority patent/PL201685B1/pl
Priority to AT01907722T priority patent/ATE292467T1/de
Priority to EP01907722A priority patent/EP1257275B1/fr
Priority to ES01907722T priority patent/ES2240416T3/es
Priority to EEP200200439A priority patent/EE04836B1/xx
Priority to US10/203,077 priority patent/US6930122B2/en
Priority to BR0108126-8A priority patent/BR0108126A/pt
Priority to YUP-590/02A priority patent/RS50404B/sr
Priority to HU0300237A priority patent/HU225328B1/hu
Priority to PT01907722T priority patent/PT1257275E/pt
Priority to BG110386A priority patent/BG110386A/en
Priority to CA002397262A priority patent/CA2397262C/en
Priority to IL15071001A priority patent/IL150710A0/xx
Priority to AU35620/01A priority patent/AU781827B2/en
Priority to DK01907722T priority patent/DK1257275T3/da
Priority to SK1129-2002A priority patent/SK284952B6/sk
Priority to CZ20022698A priority patent/CZ296685B6/cs
Priority to MXPA02007766A priority patent/MXPA02007766A/es
Priority to RU2002118309/15A priority patent/RU2257207C2/ru
Priority to DE60109903T priority patent/DE60109903T2/de
Priority to HK03103301.5A priority patent/HK1051140B/xx
Priority to SI200130365T priority patent/SI1257275T1/xx
Priority to PCT/FR2001/000356 priority patent/WO2001058450A2/fr
Priority to NZ519924A priority patent/NZ519924A/en
Priority to JP2001557560A priority patent/JP2003522145A/ja
Priority to CNB018047130A priority patent/CN1250220C/zh
Priority to ARP010100587A priority patent/AR028505A1/es
Priority to TW090102783A priority patent/TWI243677B/zh
Priority to UA2002075476A priority patent/UA72783C2/uk
Publication of FR2804604A1 publication Critical patent/FR2804604A1/fr
Priority to IS6450A priority patent/IS6450A/is
Priority to ZA200205317A priority patent/ZA200205317B/en
Priority to BG106946A priority patent/BG65856B1/bg
Priority to NO20023765A priority patent/NO324521B1/no
Priority to US11/113,864 priority patent/US20050187253A1/en
Application granted granted Critical
Publication of FR2804604B1 publication Critical patent/FR2804604B1/fr
Priority to JP2009217269A priority patent/JP2010018622A/ja
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
    • A61K31/454—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. pimozide, domperidone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
    • A61P25/34—Tobacco-abuse

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Addiction (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Psychiatry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
FR0001682A 2000-02-09 2000-02-09 Utilisation d'un antagoniste des recepteurs aux cannabinoides centraux pour la preparation de medicaments utiles pour faciliter l'arret de la consommation de tabac Expired - Fee Related FR2804604B1 (fr)

Priority Applications (36)

Application Number Priority Date Filing Date Title
FR0001682A FR2804604B1 (fr) 2000-02-09 2000-02-09 Utilisation d'un antagoniste des recepteurs aux cannabinoides centraux pour la preparation de medicaments utiles pour faciliter l'arret de la consommation de tabac
RU2002118309/15A RU2257207C2 (ru) 2000-02-09 2001-02-07 Применение антагониста центральных каннабиноидных рецепторов для приготовления лекарств, предназначенных для облегчения прекращения курения
EP01907722A EP1257275B1 (fr) 2000-02-09 2001-02-07 Utilisation d'un antagoniste des recepteurs aux cannabinoides centraux pour la preparation de medicaments utiles pour faciliter l'arret de la consommation de tabac
ES01907722T ES2240416T3 (es) 2000-02-09 2001-02-07 Utilizacion de un antagonista de los receptores de los canabinoides centrales para la preparacion de medicamentos utiles para facilitar la interrupcion del consumo de tabaco.
EEP200200439A EE04836B1 (et) 2000-02-09 2001-02-07 N-piperidino-5-(4-klorofenüül)-1-(2,4-diklorofenüül)-4-metüülpürasool-3-karboksamii di kasutamine ravimtoodete valmistamiseks, aitamaks loobuda tubakatarbimisest
US10/203,077 US6930122B2 (en) 2000-02-09 2001-02-07 Use of central cannabinoid receptor antagonist for preparing medicines designed to facilitate smoking cessation
BR0108126-8A BR0108126A (pt) 2000-02-09 2001-02-07 Utilização de um antagonista dos receptores aos canabinóides centrais para o preparo de medicamentos úteis para facilitar a parada do consumo de tabaco
YUP-590/02A RS50404B (sr) 2000-02-09 2001-02-07 Upotreba antagonista centralnog kanabinoid receptora za dobijanje medicinskih proizvoda koji pomažu u odvikavanju od pušenja
HU0300237A HU225328B1 (en) 2000-02-09 2001-02-07 Use of n-piperidino-5-(chlorophenyl)-1-(2,4-dichlorophenyl)-4-methyl-pyrazole-3-carboxamide for preparing pharmaceutical compositions designed to facilitate smoking cessation
PT01907722T PT1257275E (pt) 2000-02-09 2001-02-07 Utilizacao de um antagonista dos receptores de canabinoides centrais para a preparacao de medicamentos uteis para facilitar a paragem do consumo de tabaco
BG110386A BG110386A (en) 2000-02-09 2001-02-07 USE OF ANTAGONISTS OF CENTRAL RECEPTORS OF CANNABINOIDS FOR THE RECEIPT OF MEDICINAL PRODUCTS TO FACILITATE THE STOPPING OF TOBACCO CONSUMPTION
CA002397262A CA2397262C (en) 2000-02-09 2001-02-07 Use of central cannabinoid receptor antagonist for preparing medicines designed to facilitate smoking cessation
IL15071001A IL150710A0 (en) 2000-02-09 2001-02-07 Use of a central cannabinoid receptor antagonist for preparing medicines designed to facilitate smoking cessation
AU35620/01A AU781827B2 (en) 2000-02-09 2001-02-07 Use of central cannabinoid receptor antagonist for preparing medicines designed to facilitate smoking cessation
AT01907722T ATE292467T1 (de) 2000-02-09 2001-02-07 Verwendung eines zentralen cannabinoid-rezeptor- antagonisten für die herstelling von arzneimitteln zur erleichterung der aufgabe des tabakverbrauchs
SK1129-2002A SK284952B6 (sk) 2000-02-09 2001-02-07 Použitie N-piperidino-5-(4-chlórfenyl)-1-(2,4-dichlórfenyl)-4- metylpyrazol-3-karboxamidu na prípravu liečebných prostriedkov, farmaceutická kompozícia a súprava s jeho obsahom
CZ20022698A CZ296685B6 (cs) 2000-02-09 2001-02-07 Farmaceutické prostredky s obsahem antagonisty centrálního kanabinoidního receptoru pro napomáhání odvykání konzumaci tabáku
MXPA02007766A MXPA02007766A (es) 2000-02-09 2001-02-07 Utilizacion de un antagonista de los receptores a los canabinoides centrales para la preparacion de medicamentos utiles para facilitar la interrupcion del consumo de tabaco.
PL358221A PL201685B1 (pl) 2000-02-09 2001-02-07 Zastosowanie N-piperydyno-5-(4-chlorofenylo)-1-(2,4-dichlorofenylo)-4-metylopirazolo-3-karboksyamidu do wytwarzania leków
DK01907722T DK1257275T3 (da) 2000-02-09 2001-02-07 Anvendelse af en antagonist til centrale cannabiboidreceptorer til fremstilling af lægemidler, der er nyttige for at göre det lettere at ophöre med brug af tobak
CNB018047130A CN1250220C (zh) 2000-02-09 2001-02-07 类大麻碱中心受体拮抗剂在制造用于使停止烟草消费容易化的药物中的应用
SI200130365T SI1257275T1 (en) 2000-02-09 2001-02-07 Use of central cannabinoid receptor antagonist for preparing medicines designed to facilitate smoking cessation
PCT/FR2001/000356 WO2001058450A2 (fr) 2000-02-09 2001-02-07 Utilisation d'un antagoniste des recepteurs aux cannabinoides centraux pour la preparation de medicaments utiles pour faciliter l'arret de la consommation de tabac
NZ519924A NZ519924A (en) 2000-02-09 2001-02-07 Use of central cannabinoid receptor antagonist for preparing medicines designed to facilitate smoking cessation
JP2001557560A JP2003522145A (ja) 2000-02-09 2001-02-07 セントラルカンナビノイドレセプター拮抗剤のタバコ消費を止める助けに有用である医薬品への使用
HK03103301.5A HK1051140B (en) 2000-02-09 2001-02-07 Use of central cannabinoid receptor antagonist for preparing medicines designed to facilitate smoking cessation
DE60109903T DE60109903T2 (de) 2000-02-09 2001-02-07 Verwendung eines zentralen cannabinoid-rezeptor-antagonisten für die herstelling von arzneimitteln zur erleichterung der aufgabe des tabakverbrauchs
ARP010100587A AR028505A1 (es) 2000-02-09 2001-02-09 Utilizacion de un antagonista de los receptores de cannabinoides centrales para la preparacion de medicamentos utiles para que sea mas frcil detener el consumo de tabaco
TW090102783A TWI243677B (en) 2000-02-09 2001-02-19 Use of a central cannabinoid receptor antagonist for the preparation of medicinal products that are useful for helping to quit tobacco consumption
UA2002075476A UA72783C2 (en) 2000-02-09 2001-07-02 Agonist of central canabinoid receptors for preparation of drug disaccustoming smoking, combined pharmaceutical composition and kit
IS6450A IS6450A (is) 2000-02-09 2002-06-28 Notkun á miðju-kannabinóið-viðtaka mótlyfi til aðframleiða lyf sem eru hönnuð til að auðvelda að hætta að reykja
ZA200205317A ZA200205317B (en) 2000-02-09 2002-07-03 Use of central cannabinoid receptor antagonist for preparing medicines designed to facilitate smoking cessation.
BG106946A BG65856B1 (bg) 2000-02-09 2002-07-23 Използване на антагонисти на централни канабиноидни рецептори за получаване на лекарствени средства за улесняване спирането на консумацията на тютюн
NO20023765A NO324521B1 (no) 2000-02-09 2002-08-08 Anvendelse av sentrale cannabinoidreseptor-antagonister for fremstilling av legemidler som er anvendbare for a fremme stans av tobakksforbruk, farmasoytisk preparat, og sett.
US11/113,864 US20050187253A1 (en) 2000-02-09 2005-04-25 Medicinal kit to quit tobacco consumption comprising central cannabinoid receptor antagonist
JP2009217269A JP2010018622A (ja) 2000-02-09 2009-09-18 セントラルカンナビノイドレセプター拮抗剤のタバコ消費を止める助けに有用である医薬品への使用

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR0001682A FR2804604B1 (fr) 2000-02-09 2000-02-09 Utilisation d'un antagoniste des recepteurs aux cannabinoides centraux pour la preparation de medicaments utiles pour faciliter l'arret de la consommation de tabac

Publications (2)

Publication Number Publication Date
FR2804604A1 FR2804604A1 (fr) 2001-08-10
FR2804604B1 true FR2804604B1 (fr) 2005-05-27

Family

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Family Applications (1)

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FR0001682A Expired - Fee Related FR2804604B1 (fr) 2000-02-09 2000-02-09 Utilisation d'un antagoniste des recepteurs aux cannabinoides centraux pour la preparation de medicaments utiles pour faciliter l'arret de la consommation de tabac

Country Status (32)

Country Link
US (2) US6930122B2 (cg-RX-API-DMAC7.html)
EP (1) EP1257275B1 (cg-RX-API-DMAC7.html)
JP (2) JP2003522145A (cg-RX-API-DMAC7.html)
CN (1) CN1250220C (cg-RX-API-DMAC7.html)
AR (1) AR028505A1 (cg-RX-API-DMAC7.html)
AT (1) ATE292467T1 (cg-RX-API-DMAC7.html)
AU (1) AU781827B2 (cg-RX-API-DMAC7.html)
BG (2) BG110386A (cg-RX-API-DMAC7.html)
BR (1) BR0108126A (cg-RX-API-DMAC7.html)
CA (1) CA2397262C (cg-RX-API-DMAC7.html)
CZ (1) CZ296685B6 (cg-RX-API-DMAC7.html)
DE (1) DE60109903T2 (cg-RX-API-DMAC7.html)
DK (1) DK1257275T3 (cg-RX-API-DMAC7.html)
EE (1) EE04836B1 (cg-RX-API-DMAC7.html)
ES (1) ES2240416T3 (cg-RX-API-DMAC7.html)
FR (1) FR2804604B1 (cg-RX-API-DMAC7.html)
HU (1) HU225328B1 (cg-RX-API-DMAC7.html)
IL (1) IL150710A0 (cg-RX-API-DMAC7.html)
IS (1) IS6450A (cg-RX-API-DMAC7.html)
MX (1) MXPA02007766A (cg-RX-API-DMAC7.html)
NO (1) NO324521B1 (cg-RX-API-DMAC7.html)
NZ (1) NZ519924A (cg-RX-API-DMAC7.html)
PL (1) PL201685B1 (cg-RX-API-DMAC7.html)
PT (1) PT1257275E (cg-RX-API-DMAC7.html)
RS (1) RS50404B (cg-RX-API-DMAC7.html)
RU (1) RU2257207C2 (cg-RX-API-DMAC7.html)
SI (1) SI1257275T1 (cg-RX-API-DMAC7.html)
SK (1) SK284952B6 (cg-RX-API-DMAC7.html)
TW (1) TWI243677B (cg-RX-API-DMAC7.html)
UA (1) UA72783C2 (cg-RX-API-DMAC7.html)
WO (1) WO2001058450A2 (cg-RX-API-DMAC7.html)
ZA (1) ZA200205317B (cg-RX-API-DMAC7.html)

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FR2758723B1 (fr) * 1997-01-28 1999-04-23 Sanofi Sa Utilisation des antagonistes des recepteurs aux cannabinoides centraux pour la preparation de medicaments
FR2765107B1 (fr) * 1997-06-26 2000-03-24 Sanofi Sa Utilisation d'un antagoniste specifique des recepteurs 5ht2 pour la preparation de medicaments utiles dans le traitement du syndrome d'apnee du sommeil
FR2789079B3 (fr) 1999-02-01 2001-03-02 Sanofi Synthelabo Derive d'acide pyrazolecarboxylique, sa preparation, les compositions pharmaceutiques en contenant
FR2804604B1 (fr) * 2000-02-09 2005-05-27 Sanofi Synthelabo Utilisation d'un antagoniste des recepteurs aux cannabinoides centraux pour la preparation de medicaments utiles pour faciliter l'arret de la consommation de tabac

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YU59002A (sh) 2005-07-19
US20050187253A1 (en) 2005-08-25
PL358221A1 (en) 2004-08-09
IS6450A (is) 2002-06-28
BG106946A (bg) 2003-05-30
PT1257275E (pt) 2005-07-29
EP1257275B1 (fr) 2005-04-06
HUP0300237A2 (hu) 2003-07-28
NZ519924A (en) 2005-01-28
HK1051140A1 (en) 2003-07-25
AU3562001A (en) 2001-08-20
RU2002118309A (ru) 2004-02-20
CN1250220C (zh) 2006-04-12
AU781827B2 (en) 2005-06-16
NO20023765D0 (no) 2002-08-08
MXPA02007766A (es) 2002-10-11
EE04836B1 (et) 2007-06-15
BR0108126A (pt) 2003-01-28
ATE292467T1 (de) 2005-04-15
DE60109903D1 (de) 2005-05-12
JP2010018622A (ja) 2010-01-28
IL150710A0 (en) 2003-02-12
WO2001058450A3 (fr) 2002-04-25
SK284952B6 (sk) 2006-03-02
US6930122B2 (en) 2005-08-16
CZ296685B6 (cs) 2006-05-17
NO20023765L (no) 2002-10-09
DE60109903T2 (de) 2006-02-09
TWI243677B (en) 2005-11-21
JP2003522145A (ja) 2003-07-22
BG110386A (en) 2009-09-30
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HUP0300237A3 (en) 2003-09-29
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FR2804604A1 (fr) 2001-08-10
PL201685B1 (pl) 2009-04-30
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WO2001058450A2 (fr) 2001-08-16
RU2257207C2 (ru) 2005-07-27
BG65856B1 (bg) 2010-03-31
UA72783C2 (en) 2005-04-15
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