DK1257275T3 - Anvendelse af en antagonist til centrale cannabiboidreceptorer til fremstilling af lægemidler, der er nyttige for at göre det lettere at ophöre med brug af tobak - Google Patents

Anvendelse af en antagonist til centrale cannabiboidreceptorer til fremstilling af lægemidler, der er nyttige for at göre det lettere at ophöre med brug af tobak

Info

Publication number
DK1257275T3
DK1257275T3 DK01907722T DK01907722T DK1257275T3 DK 1257275 T3 DK1257275 T3 DK 1257275T3 DK 01907722 T DK01907722 T DK 01907722T DK 01907722 T DK01907722 T DK 01907722T DK 1257275 T3 DK1257275 T3 DK 1257275T3
Authority
DK
Denmark
Prior art keywords
cannabiboid
cessation
antagonist
receptors
facilitate
Prior art date
Application number
DK01907722T
Other languages
Danish (da)
English (en)
Inventor
Jean Charles Blanchard
Francois Menard
Original Assignee
Sanofi Aventis
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sanofi Aventis filed Critical Sanofi Aventis
Application granted granted Critical
Publication of DK1257275T3 publication Critical patent/DK1257275T3/da

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
    • A61K31/454—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. pimozide, domperidone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
    • A61P25/34—Tobacco-abuse

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Addiction (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Psychiatry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
DK01907722T 2000-02-09 2001-02-07 Anvendelse af en antagonist til centrale cannabiboidreceptorer til fremstilling af lægemidler, der er nyttige for at göre det lettere at ophöre med brug af tobak DK1257275T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR0001682A FR2804604B1 (fr) 2000-02-09 2000-02-09 Utilisation d'un antagoniste des recepteurs aux cannabinoides centraux pour la preparation de medicaments utiles pour faciliter l'arret de la consommation de tabac
PCT/FR2001/000356 WO2001058450A2 (fr) 2000-02-09 2001-02-07 Utilisation d'un antagoniste des recepteurs aux cannabinoides centraux pour la preparation de medicaments utiles pour faciliter l'arret de la consommation de tabac

Publications (1)

Publication Number Publication Date
DK1257275T3 true DK1257275T3 (da) 2005-08-08

Family

ID=8846875

Family Applications (1)

Application Number Title Priority Date Filing Date
DK01907722T DK1257275T3 (da) 2000-02-09 2001-02-07 Anvendelse af en antagonist til centrale cannabiboidreceptorer til fremstilling af lægemidler, der er nyttige for at göre det lettere at ophöre med brug af tobak

Country Status (32)

Country Link
US (2) US6930122B2 (cg-RX-API-DMAC7.html)
EP (1) EP1257275B1 (cg-RX-API-DMAC7.html)
JP (2) JP2003522145A (cg-RX-API-DMAC7.html)
CN (1) CN1250220C (cg-RX-API-DMAC7.html)
AR (1) AR028505A1 (cg-RX-API-DMAC7.html)
AT (1) ATE292467T1 (cg-RX-API-DMAC7.html)
AU (1) AU781827B2 (cg-RX-API-DMAC7.html)
BG (2) BG110386A (cg-RX-API-DMAC7.html)
BR (1) BR0108126A (cg-RX-API-DMAC7.html)
CA (1) CA2397262C (cg-RX-API-DMAC7.html)
CZ (1) CZ296685B6 (cg-RX-API-DMAC7.html)
DE (1) DE60109903T2 (cg-RX-API-DMAC7.html)
DK (1) DK1257275T3 (cg-RX-API-DMAC7.html)
EE (1) EE04836B1 (cg-RX-API-DMAC7.html)
ES (1) ES2240416T3 (cg-RX-API-DMAC7.html)
FR (1) FR2804604B1 (cg-RX-API-DMAC7.html)
HU (1) HU225328B1 (cg-RX-API-DMAC7.html)
IL (1) IL150710A0 (cg-RX-API-DMAC7.html)
IS (1) IS6450A (cg-RX-API-DMAC7.html)
MX (1) MXPA02007766A (cg-RX-API-DMAC7.html)
NO (1) NO324521B1 (cg-RX-API-DMAC7.html)
NZ (1) NZ519924A (cg-RX-API-DMAC7.html)
PL (1) PL201685B1 (cg-RX-API-DMAC7.html)
PT (1) PT1257275E (cg-RX-API-DMAC7.html)
RS (1) RS50404B (cg-RX-API-DMAC7.html)
RU (1) RU2257207C2 (cg-RX-API-DMAC7.html)
SI (1) SI1257275T1 (cg-RX-API-DMAC7.html)
SK (1) SK284952B6 (cg-RX-API-DMAC7.html)
TW (1) TWI243677B (cg-RX-API-DMAC7.html)
UA (1) UA72783C2 (cg-RX-API-DMAC7.html)
WO (1) WO2001058450A2 (cg-RX-API-DMAC7.html)
ZA (1) ZA200205317B (cg-RX-API-DMAC7.html)

Families Citing this family (42)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2804604B1 (fr) * 2000-02-09 2005-05-27 Sanofi Synthelabo Utilisation d'un antagoniste des recepteurs aux cannabinoides centraux pour la preparation de medicaments utiles pour faciliter l'arret de la consommation de tabac
US6462237B1 (en) * 2001-06-14 2002-10-08 Usv Limited Cyclodextrin stabilized pharmaceutical compositions of bupropion hydrochloride
AU2002356039A1 (en) 2001-08-13 2003-03-03 Honeywell International Inc. Methods of conducting wafer level burn-in of electronic devices
JP2005533748A (ja) 2002-03-08 2005-11-10 シグナル ファーマシューティカルズ，インコーポレイテッド 増殖性障害および癌を治療、予防、または管理するための併用療法
WO2003077847A2 (en) 2002-03-12 2003-09-25 Merck & Co., Inc. Substituted amides
JP2005528366A (ja) 2002-03-26 2005-09-22 メルク　エンド　カムパニー　インコーポレーテッド カンナビノイド受容体モジュレータとしてのスピロ環式アミド
JP2005531520A (ja) 2002-03-28 2005-10-20 メルク　エンド　カムパニー　インコーポレーテッド 置換２，３−ジフェニルピリジン類
WO2003086288A2 (en) 2002-04-12 2003-10-23 Merck & Co., Inc. Bicyclic amides
US6825209B2 (en) 2002-04-15 2004-11-30 Research Triangle Institute Compounds having unique CB1 receptor binding selectivity and methods for their production and use
ATE375349T1 (de) 2002-08-02 2007-10-15 Merck & Co Inc Substituierte furo(2,3-b)pyridin derivate
CA2499497A1 (en) 2002-09-27 2004-04-08 Merck & Co., Inc. Substituted pyrimidines
US7129239B2 (en) 2002-10-28 2006-10-31 Pfizer Inc. Purine compounds and uses thereof
US7247628B2 (en) 2002-12-12 2007-07-24 Pfizer, Inc. Cannabinoid receptor ligands and uses thereof
WO2004058145A2 (en) 2002-12-19 2004-07-15 Merck & Co., Inc. Substituted amides
US7329658B2 (en) 2003-02-06 2008-02-12 Pfizer Inc Cannabinoid receptor ligands and uses thereof
US7176210B2 (en) 2003-02-10 2007-02-13 Pfizer Inc. Cannabinoid receptor ligands and uses thereof
US7145012B2 (en) 2003-04-23 2006-12-05 Pfizer Inc. Cannabinoid receptor ligands and uses thereof
US7268133B2 (en) 2003-04-23 2007-09-11 Pfizer, Inc. Patent Department Cannabinoid receptor ligands and uses thereof
US20040224962A1 (en) * 2003-05-09 2004-11-11 Pfizer Inc Pharmaceutical composition for the treatment of obesity or to facilitate or promote weight loss
US20040224963A1 (en) * 2003-05-09 2004-11-11 Pfizer Inc Pharmaceutical composition for the prevention and treatment of nicotine addiction in a mammal
CA2526103A1 (en) * 2003-05-20 2004-12-29 Bob M. Ii Moore Cannabinoid derivatives, methods of making, and use thereof
US7232823B2 (en) 2003-06-09 2007-06-19 Pfizer, Inc. Cannabinoid receptor ligands and uses thereof
CA2543882A1 (en) * 2003-10-30 2005-05-19 Merck & Co., Inc. Aralkyl amines as cannabinoid receptor modulators
MX2007000491A (es) 2004-07-12 2007-03-28 Cadila Healthcare Ltd Nuevos compuestos heterociclicos.
US20060025448A1 (en) 2004-07-22 2006-02-02 Cadila Healthcare Limited Hair growth stimulators
ES2435790T3 (es) 2004-12-03 2013-12-23 Intervet International B.V. Piperazinas sustituidas como antagonistas de CB1
NZ569814A (en) * 2006-01-18 2011-10-28 Schering Corp Cannibinoid receptor modulators
WO2007121687A1 (en) * 2006-04-26 2007-11-01 Institute Of Pharmacology And Toxicology Academy Of Military Medical Sciences P.L.A. China 4-methyl-1h-diaryl pyrazole derivatives and their uses as medicament
CN101062919B (zh) * 2006-04-26 2012-08-15 中国人民解放军军事医学科学院毒物药物研究所 4-甲基-1h-二芳基吡唑衍生物及其作为药物的用途
US20070287734A1 (en) * 2006-06-09 2007-12-13 Auspex Pharmaceuticals, Inc. Preparation and utility of substituted pyrazole compounds with cannabinoid receptor activity
RU2477634C2 (ru) * 2006-06-16 2013-03-20 Теракос, Инк. Лечение психологических состояний с применением антагонистов m1-мускариновых рецепторов
WO2008046905A1 (en) * 2006-10-20 2008-04-24 Solvay Pharmaceuticals B.V. Micellar nanoparticles of chemical substances
WO2008130616A2 (en) * 2007-04-19 2008-10-30 Schering Corporation Diaryl morpholines as cb1 modulators
WO2009005671A2 (en) * 2007-06-28 2009-01-08 Schering Corporation Substituted piperazines as cb1 antagonists
EP2170846A2 (en) * 2007-06-28 2010-04-07 Intervet International BV Substituted piperazines as cb1 antagonists
EP2095814A1 (de) * 2008-02-26 2009-09-02 Wolfgang J. Kox Medikamentengestützter Nikotinentzug
WO2010018856A1 (ja) * 2008-08-13 2010-02-18 持田製薬株式会社 カンナビノイド受容体関連疾患の予防／改善または治療剤
RU2533224C2 (ru) * 2010-07-21 2014-11-20 Мапикс Эс.Эй.Ар.Эл. Способ лечения зависимости от психоактивных веществ, алкоголизма и табакокурения и лекарственное средство для лечения зависимости от психоактивных веществ, алкоголизма и табакокурения
WO2013068371A1 (en) 2011-11-08 2013-05-16 Intervet International B.V. Soft chewable dosage form compositions of cannabinoid receptor type 1 (cb-1) antagonists
WO2014181357A1 (en) * 2013-05-09 2014-11-13 Council Of Scientific & Industrial Research Novel pyrazole derivatives with silicon incorporation
US20200035118A1 (en) 2018-07-27 2020-01-30 Joseph Pandolfino Methods and products to facilitate smokers switching to a tobacco heating product or e-cigarettes
US10897925B2 (en) 2018-07-27 2021-01-26 Joseph Pandolfino Articles and formulations for smoking products and vaporizers

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5780051A (en) * 1992-04-02 1998-07-14 Dynagen, Inc. Methods and articles of manufacture for nicotine cessation and monitoring nicotine use
FR2713225B1 (fr) * 1993-12-02 1996-03-01 Sanofi Sa N-pipéridino-3-pyrazolecarboxamide substitué.
FR2692575B1 (fr) * 1992-06-23 1995-06-30 Sanofi Elf Nouveaux derives du pyrazole, procede pour leur preparation et compositions pharmaceutiques les contenant.
US5596106A (en) * 1994-07-15 1997-01-21 Eli Lilly And Company Cannabinoid receptor antagonists
FR2758723B1 (fr) * 1997-01-28 1999-04-23 Sanofi Sa Utilisation des antagonistes des recepteurs aux cannabinoides centraux pour la preparation de medicaments
FR2765107B1 (fr) * 1997-06-26 2000-03-24 Sanofi Sa Utilisation d'un antagoniste specifique des recepteurs 5ht2 pour la preparation de medicaments utiles dans le traitement du syndrome d'apnee du sommeil
FR2789079B3 (fr) 1999-02-01 2001-03-02 Sanofi Synthelabo Derive d'acide pyrazolecarboxylique, sa preparation, les compositions pharmaceutiques en contenant
FR2804604B1 (fr) * 2000-02-09 2005-05-27 Sanofi Synthelabo Utilisation d'un antagoniste des recepteurs aux cannabinoides centraux pour la preparation de medicaments utiles pour faciliter l'arret de la consommation de tabac

Also Published As

Publication number Publication date
CA2397262A1 (en) 2001-08-16
CA2397262C (en) 2007-09-11
US20030087933A1 (en) 2003-05-08
YU59002A (sh) 2005-07-19
US20050187253A1 (en) 2005-08-25
PL358221A1 (en) 2004-08-09
IS6450A (is) 2002-06-28
BG106946A (bg) 2003-05-30
PT1257275E (pt) 2005-07-29
EP1257275B1 (fr) 2005-04-06
HUP0300237A2 (hu) 2003-07-28
NZ519924A (en) 2005-01-28
HK1051140A1 (en) 2003-07-25
AU3562001A (en) 2001-08-20
RU2002118309A (ru) 2004-02-20
CN1250220C (zh) 2006-04-12
AU781827B2 (en) 2005-06-16
NO20023765D0 (no) 2002-08-08
MXPA02007766A (es) 2002-10-11
EE04836B1 (et) 2007-06-15
BR0108126A (pt) 2003-01-28
ATE292467T1 (de) 2005-04-15
DE60109903D1 (de) 2005-05-12
JP2010018622A (ja) 2010-01-28
FR2804604B1 (fr) 2005-05-27
IL150710A0 (en) 2003-02-12
WO2001058450A3 (fr) 2002-04-25
SK284952B6 (sk) 2006-03-02
US6930122B2 (en) 2005-08-16
CZ296685B6 (cs) 2006-05-17
NO20023765L (no) 2002-10-09
DE60109903T2 (de) 2006-02-09
TWI243677B (en) 2005-11-21
JP2003522145A (ja) 2003-07-22
BG110386A (en) 2009-09-30
SI1257275T1 (en) 2005-10-31
NO324521B1 (no) 2007-11-12
ZA200205317B (en) 2003-09-04
EE200200439A (et) 2003-12-15
RS50404B (sr) 2009-12-31
HUP0300237A3 (en) 2003-09-29
AR028505A1 (es) 2003-05-14
FR2804604A1 (fr) 2001-08-10
PL201685B1 (pl) 2009-04-30
HU225328B1 (en) 2006-09-28
SK11292002A3 (sk) 2003-02-04
WO2001058450A2 (fr) 2001-08-16
RU2257207C2 (ru) 2005-07-27
BG65856B1 (bg) 2010-03-31
UA72783C2 (en) 2005-04-15
CN1406128A (zh) 2003-03-26
EP1257275A2 (fr) 2002-11-20
ES2240416T3 (es) 2005-10-16
CZ20022698A3 (cs) 2002-11-13

Similar Documents

Publication Publication Date Title
DK1257275T3 (da) Anvendelse af en antagonist til centrale cannabiboidreceptorer til fremstilling af lægemidler, der er nyttige for at göre det lettere at ophöre med brug af tobak
DK1221952T3 (da) Anvendelse af en antagonist til centrale cannaboidreceptorer med henblik på fremstilling af lægemidler
DK1309559T3 (da) 4-phenyl-pyridinderivater som neurokinin-1-receptorantagonister
NO20031474L (no) Metabotropiske glutamatreseptorantagonister
NO20013572L (no) Fremgangsmåte for utförelse av borehullsundersökelser, med bruk av kontinuerlige målinger
ATE368659T1 (de) Thrombinrezeptorantagonisten
DK1571145T3 (da) Substitueret piperidinforbindelser til anvendelse som H3 histaminreceptor-antagonister
NO20032503L (no) Fenyletenyl- eller fenyletynylderivater som glutamatreseptorantagonister
PL365377A1 (en) Amide derivatives as nmda receptor antagonists
SMAP200600024A (it) 2,6-Biseteroaril-4-amminopirimidine come antagonisti del recettore dell'adenosia
DK1305319T3 (da) 4-phenyl-pyridinderivater som neurokinin-1-receptorantagonister
IS6569A (is) Sýklóhexýlamín afleiða sem valvís NMDA viðtakamótlyf af undirgerð
NO20032142D0 (no) Substituerte 2-fenylaminoimidazolin-fenylketon-derivater som IP-antagonister
ATE432282T1 (de) 2-alkinyl- und 2-alkenyl-pyrazolo-ä4,3-eü -1,2,4- triazolo-ä1,5-cü -pyrimidinadenosin a2a rezeptorantagonisten
IS6821A (is) Samrunnar afleiður púríns sem mótlyf A1-adenósínviðtakans
ATE492535T1 (de) 4-piperidinylalkylamin-derivate, antagonisten von muscarinrezeptoren
DE60130000D1 (de) Zwitterionische tachykinin-rezeptor-antagonisten
DK1176144T3 (da) Nye N-triazolylmethyl-piperazinderivater som neurokininreceptor-antagonister
DK1960387T3 (da) Isoquinolin- og benzo[h]isoquinolinderivater, fremstilling deraf og terapeutisk anvendelse deraf som antagonister af histamin H3-receptoren
DE60209885D1 (de) Crf receptor antagonisten
DK1347760T3 (da) Farmaceutiske kompositioner med NMDA receptor agonister
DK1600446T3 (da) Ny 3,3-dimethyl-5-cyano-benzoxepin-derivater anvendelige til fremstillingen af 5-formyl-benzoxepin- derivater
DK1171419T3 (da) Biphenylderivater som antagonister til Neurokinin-1-receptoren