FR2739028B1 - Dispositif d'encapsulation de cellules ameliore - Google Patents
Dispositif d'encapsulation de cellules amelioreInfo
- Publication number
- FR2739028B1 FR2739028B1 FR9611420A FR9611420A FR2739028B1 FR 2739028 B1 FR2739028 B1 FR 2739028B1 FR 9611420 A FR9611420 A FR 9611420A FR 9611420 A FR9611420 A FR 9611420A FR 2739028 B1 FR2739028 B1 FR 2739028B1
- Authority
- FR
- France
- Prior art keywords
- encapsulation device
- improved cell
- cell encapsulation
- improved
- encapsulation
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
- A61K9/0024—Solid, semi-solid or solidifying implants, which are implanted or injected in body tissue
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/022—Artificial gland structures using bioreactors
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12G—WINE; PREPARATION THEREOF; ALCOHOLIC BEVERAGES; PREPARATION OF ALCOHOLIC BEVERAGES NOT PROVIDED FOR IN SUBCLASSES C12C OR C12H
- C12G1/00—Preparation of wine or sparkling wine
- C12G1/06—Preparation of sparkling wine; Impregnation of wine with carbon dioxide
- C12G1/064—Preparation of sparkling wine; Impregnation of wine with carbon dioxide using enclosed yeast
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M23/00—Constructional details, e.g. recesses, hinges
- C12M23/02—Form or structure of the vessel
- C12M23/08—Flask, bottle or test tube
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M23/00—Constructional details, e.g. recesses, hinges
- C12M23/22—Transparent or translucent parts
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M23/00—Constructional details, e.g. recesses, hinges
- C12M23/34—Internal compartments or partitions
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M23/00—Constructional details, e.g. recesses, hinges
- C12M23/38—Caps; Covers; Plugs; Pouring means
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M25/00—Means for supporting, enclosing or fixing the microorganisms, e.g. immunocoatings
- C12M25/16—Particles; Beads; Granular material; Encapsulation
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M33/00—Means for introduction, transport, positioning, extraction, harvesting, peeling or sampling of biological material in or from the apparatus
- C12M33/14—Means for introduction, transport, positioning, extraction, harvesting, peeling or sampling of biological material in or from the apparatus with filters, sieves or membranes
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Zoology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Wood Science & Technology (AREA)
- General Health & Medical Sciences (AREA)
- Biomedical Technology (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- Microbiology (AREA)
- Genetics & Genomics (AREA)
- Sustainable Development (AREA)
- Biotechnology (AREA)
- Clinical Laboratory Science (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Transplantation (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Mycology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Dermatology (AREA)
- Neurosurgery (AREA)
- Molecular Biology (AREA)
- Immunology (AREA)
- Cardiology (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Heart & Thoracic Surgery (AREA)
- Vascular Medicine (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Diaphragms For Electromechanical Transducers (AREA)
- Telephone Function (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US53292595A | 1995-09-22 | 1995-09-22 |
Publications (2)
Publication Number | Publication Date |
---|---|
FR2739028A1 FR2739028A1 (fr) | 1997-03-28 |
FR2739028B1 true FR2739028B1 (fr) | 1998-06-26 |
Family
ID=24123770
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
FR9611420A Expired - Lifetime FR2739028B1 (fr) | 1995-09-22 | 1996-09-19 | Dispositif d'encapsulation de cellules ameliore |
Country Status (6)
Country | Link |
---|---|
US (1) | US5902745A (fr) |
AU (1) | AU6854696A (fr) |
FR (1) | FR2739028B1 (fr) |
IT (1) | IT1284549B1 (fr) |
NL (1) | NL1004082C2 (fr) |
WO (1) | WO1997010807A1 (fr) |
Families Citing this family (86)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5855613A (en) | 1995-10-13 | 1999-01-05 | Islet Sheet Medical, Inc. | Retrievable bioartificial implants having dimensions allowing rapid diffusion of oxygen and rapid biological response to physiological change |
DE19631320A1 (de) * | 1996-08-02 | 1998-02-05 | Bayer Ag | In Hydrogelen eingebettetes biologisches Material, ein Verfahren zu dessen Einbettung sowie dessen Verwendung als künstliches Saatgut |
US6303136B1 (en) * | 1998-04-13 | 2001-10-16 | Neurotech S.A. | Cells or tissue attached to a non-degradable filamentous matrix encapsulated by a semi-permeable membrane |
US6391149B1 (en) * | 1998-06-04 | 2002-05-21 | Advanced Cardiovascular Systems, Inc. | Method and apparatus for concentrating a solute in solution with a solvent |
US8012500B2 (en) * | 2000-01-01 | 2011-09-06 | Beta-O2 Technologies Ltd. | Implantable device |
IL134009A (en) * | 2000-01-12 | 2011-07-31 | Bo2 Technologies Ltd | Transplant device |
US6617151B1 (en) * | 2000-02-29 | 2003-09-09 | Gore Enterprise Holdings, Inc. | Method of closing a cell containment device with a wet seal |
US6810880B1 (en) | 2000-04-10 | 2004-11-02 | Gore Enterprise Holdings, Inc. | Surgical implant system |
FR2820057A1 (fr) * | 2001-01-30 | 2002-08-02 | Ct De Transfert De Technologie | Membrane pour chambre d'encapsulation de cellules produisant au moins une substance biologiquement active et organe bio-artificiel comprenant une telle membrane |
DE10134447B4 (de) * | 2001-07-16 | 2006-04-20 | Gkss-Forschungszentrum Geesthacht Gmbh | Trägermembran für Biohybridorgane, Verfahren zur Herstellung und Verwendung |
CA2474186A1 (fr) | 2002-02-08 | 2003-08-14 | Xcyte Therapies, Inc. | Compositions et procedes de restauration de reponse immune chez des patients souffrant de deficiences immunologiques |
US20030225439A1 (en) * | 2002-05-31 | 2003-12-04 | Cook Alonzo D. | Implantable product with improved aqueous interface characteristics and method for making and using same |
US20040151704A1 (en) | 2002-06-28 | 2004-08-05 | Xcyte Therapies, Inc. | Compositions and methods for restoring immune repertoire in patients with immunological defects related to autoimmunity and organ or hematopoietic stem cell transplantation |
US7025982B2 (en) * | 2002-09-19 | 2006-04-11 | Medtronic, Inc. | Medical assembly suitable for long-term implantation and method for fabricating the same |
JP2006524991A (ja) * | 2003-05-08 | 2006-11-09 | エクサイト セラピーズ インコーポレーティッド | 抗原特異的t細胞の作製および単離の方法 |
US20050015140A1 (en) * | 2003-07-14 | 2005-01-20 | Debeer Nicholas | Encapsulation device and methods of use |
US9861346B2 (en) | 2003-07-14 | 2018-01-09 | W. L. Gore & Associates, Inc. | Patent foramen ovale (PFO) closure device with linearly elongating petals |
US8257963B2 (en) * | 2007-06-01 | 2012-09-04 | Depuy Mitek, Inc. | Chondrocyte container and method of use |
US7897384B2 (en) * | 2003-09-08 | 2011-03-01 | Ethicon, Inc. | Chondrocyte therapeutic delivery system |
US7927599B2 (en) * | 2003-09-08 | 2011-04-19 | Ethicon, Inc. | Chondrocyte therapeutic delivery system |
EP1682438B1 (fr) * | 2003-10-30 | 2013-05-08 | Cytonome/ST, LLC | Structure de flux de gaine hydrodynamique multicouche |
SG137871A1 (en) | 2004-06-01 | 2007-12-28 | In Motion Investment Ltd | In vitro techniques for use with stem cells |
EP2532356A1 (fr) | 2004-07-14 | 2012-12-12 | Glusense Ltd. | Sources d'alimentation implantables et capteurs |
ME01142B (me) * | 2005-01-07 | 2013-03-20 | Pfizer Prod Inc | Heteroaromatična jedinjenja hinolina i njihova upotreba kao pde10 inhibitora |
US7381331B2 (en) * | 2005-09-30 | 2008-06-03 | General Electric Company | Hydrophilic membrane and associated method |
US7631768B2 (en) * | 2005-11-04 | 2009-12-15 | General Electric Company | Membrane and associated method |
US7291696B2 (en) * | 2005-11-04 | 2007-11-06 | General Electric Company | Composition and associated method |
TW200734462A (en) | 2006-03-08 | 2007-09-16 | In Motion Invest Ltd | Regulating stem cells |
US7923054B2 (en) * | 2006-04-19 | 2011-04-12 | Gore Enterprise Holdings, Inc. | Functional porous substrates for attaching biomolecules |
US20100047311A1 (en) * | 2006-11-22 | 2010-02-25 | Beta O2 Technologies Ltd. | Protecting algae from body fluids |
ES2659988T3 (es) * | 2006-11-28 | 2018-03-20 | Beta O2 Technologies Ltd. | Suministro de oxígeno para el transplante celular y la vascularización |
EP1927652A1 (fr) * | 2006-11-29 | 2008-06-04 | Koninklijke Philips Electronics N.V. | Reseau de cellules ou matrice cellulaire et electroporation |
WO2008100559A2 (fr) * | 2007-02-14 | 2008-08-21 | Bioengine, Inc. | Dispositifs médicaux comprenant une vascularisation de canaux microfluidiques |
WO2008124603A1 (fr) | 2007-04-05 | 2008-10-16 | Nmt Medical, Inc. | Dispositif de fermeture septale à mécanisme de centrage |
EP2185730A4 (fr) | 2007-08-23 | 2010-10-27 | Intrexon Corp | Procédés et compositions de diagnostic d'une maladie |
WO2009031154A2 (fr) * | 2007-09-07 | 2009-03-12 | Beta O2 Technologies Ltd. | Couche d'air pour soutenir des cellules |
RU2499599C2 (ru) | 2007-09-28 | 2013-11-27 | Интрексон Корпорейшн | Конструкции терапевтического переключения генов и биореакторы для экспрессии биотерапевтических молекул и их применение |
US20130165967A1 (en) | 2008-03-07 | 2013-06-27 | W.L. Gore & Associates, Inc. | Heart occlusion devices |
US20100080784A1 (en) * | 2008-09-12 | 2010-04-01 | Torrey Pines Institute For Molecular Studies | Methods for treating cachexia and lymphopenia |
US9540630B2 (en) * | 2008-09-17 | 2017-01-10 | Beta O2 Technologies Ltd. | Optimization of alginate encapsulation of islets for transplantation |
EP4176888A1 (fr) * | 2008-11-14 | 2023-05-10 | ViaCyte, Inc. | Encapsulation de cellules pancréatiques dérivées de cellules souches pluripotentes humaines |
US8043271B2 (en) * | 2008-11-26 | 2011-10-25 | Beta 02 Technologies Ltd. | Apparatus for transportation of oxygen to implanted cells |
US20100160749A1 (en) * | 2008-12-24 | 2010-06-24 | Glusense Ltd. | Implantable optical glucose sensing |
US20120029556A1 (en) | 2009-06-22 | 2012-02-02 | Masters Steven J | Sealing device and delivery system |
US8956389B2 (en) | 2009-06-22 | 2015-02-17 | W. L. Gore & Associates, Inc. | Sealing device and delivery system |
WO2011154941A2 (fr) | 2010-06-07 | 2011-12-15 | Beta-O2 Technologies Ltd. | Barrière immunitaire multicouche pour cellules donneuses |
US20120208255A1 (en) * | 2011-02-14 | 2012-08-16 | Geosynfuels, Llc | Apparatus and process for production of an encapsulated cell product |
US9415193B2 (en) | 2011-03-04 | 2016-08-16 | W. L. Gore & Associates, Inc. | Eluting medical devices |
US9037205B2 (en) | 2011-06-30 | 2015-05-19 | Glusense, Ltd | Implantable optical glucose sensing |
US9770232B2 (en) | 2011-08-12 | 2017-09-26 | W. L. Gore & Associates, Inc. | Heart occlusion devices |
US9644179B2 (en) | 2011-11-23 | 2017-05-09 | The Trustees Of The University Of Pennsylvania | Use of PDL1 expressing cells to convert T cells into regulatory T cells |
USD726306S1 (en) | 2011-12-12 | 2015-04-07 | Viacyte, Inc. | Cell encapsulation device |
USD726307S1 (en) | 2011-12-12 | 2015-04-07 | Viacyte Inc. | Cell encapsulation device |
USD728095S1 (en) | 2011-12-12 | 2015-04-28 | Viacyte, Inc. | Cell encapsulation device |
USD734847S1 (en) | 2012-05-31 | 2015-07-21 | Viacyte, Inc. | Cell encapsulation device |
US10173038B2 (en) | 2012-09-05 | 2019-01-08 | W. L. Gore & Associates, Inc. | Retractable sheath devices, systems, and methods |
US10828019B2 (en) | 2013-01-18 | 2020-11-10 | W.L. Gore & Associates, Inc. | Sealing device and delivery system |
CN105163688B (zh) | 2013-03-07 | 2018-11-20 | 韦尔赛特公司 | 三维大容量细胞包封装置组件 |
US10240125B2 (en) | 2013-03-14 | 2019-03-26 | Immusoft Corporation | Methods for in vitro memory B cell differentiation and transduction with VSV-G pseudotyped viral vectors |
NZ711384A (en) | 2013-03-14 | 2018-06-29 | Cytonome St Llc | Hydrodynamic focusing apparatus and methods |
CA3059017C (fr) | 2013-09-24 | 2021-05-25 | Giner Life Sciences, Inc. | Systeme pour le traitement gazeux d'un implant cellulaire |
US9808230B2 (en) | 2014-06-06 | 2017-11-07 | W. L. Gore & Associates, Inc. | Sealing device and delivery system |
CN106999118B (zh) | 2014-10-13 | 2020-07-17 | 葡萄糖传感器公司 | 分析物感测装置 |
CA2964953A1 (fr) | 2014-10-31 | 2016-05-06 | The Trustees Of The University Of Pennsylvania | Modification de l'expression genetique dans les cellules cart et utilisations associees |
ES2910227T3 (es) | 2014-10-31 | 2022-05-12 | Univ Pennsylvania | Composición y métodos para la estimulación y expansión de células T |
DK3234107T3 (da) | 2014-12-19 | 2022-10-17 | Immusoft Corp | B-celler til in vivo-levering af terapeutiske midler |
EP4223873A3 (fr) | 2015-01-31 | 2023-09-06 | The Trustees of the University of Pennsylvania | Compositions et procédés d'administration de molécules thérapeutiques par des lymphocytes t |
EP3259284B1 (fr) | 2015-02-16 | 2020-04-01 | The Trustees of the University of Pennsylvania | Récepteur des cellules t entièrement humain spécifique de l'épitope 369-377 dérivé de la protéine réceptrice her2/neu (erbb2) |
TW201642820A (zh) * | 2015-02-19 | 2016-12-16 | 健生生物科技公司 | 細胞封裝加載裝置 |
EP3445872A1 (fr) | 2016-04-20 | 2019-02-27 | Glusense Ltd. | Molécules de détection de glucose par fret |
US10039882B2 (en) * | 2016-09-01 | 2018-08-07 | Arthrex, Inc. | Binding syringe |
US11338068B2 (en) * | 2016-11-08 | 2022-05-24 | W. L. Gore & Associates, Inc. | Two-part implantable therapy delivery device |
USD824042S1 (en) * | 2016-11-10 | 2018-07-24 | Viacyte, Inc. | Perforated cell encapsulation device |
CN110167455B (zh) | 2016-11-10 | 2022-10-11 | 韦尔赛特公司 | 含有pdx1胰腺内胚层细胞的细胞递送装置及其方法 |
AU2017361260B2 (en) | 2016-11-15 | 2023-06-08 | Giner, Inc. | Percutaneous gas diffusion device suitable for use with a subcutaneous implant |
US10863737B2 (en) | 2017-05-22 | 2020-12-15 | Drobot Biotechnology Limited Company | Culture container, and system and method of transferring a cultured organism between culture containers |
RU2020133851A (ru) | 2018-03-16 | 2022-04-19 | Иммьюсофт Корпорейшн | B-клетки, генетически модифицированные для секреции фоллистатина, и способы их применения для лечения связанных с фоллистатином заболеваний, состояний, нарушений и для увеличения роста и силы мышц |
CN108379663B (zh) * | 2018-04-24 | 2023-05-26 | 中国人民解放军第四军医大学 | 一种多孔规则体支架材料中截留及富集细胞的装置和方法 |
AU2019287735A1 (en) | 2018-06-14 | 2021-01-28 | W. L. Gore & Associates, Inc. | Epitheliazing microporous biomaterial for use in avascular environments and in corneal implants |
CN112955465A (zh) | 2018-07-03 | 2021-06-11 | 马伦戈治疗公司 | 抗tcr抗体分子及其用途 |
CN112770697B (zh) * | 2018-09-26 | 2024-05-14 | W.L.戈尔及同仁股份有限公司 | 具有可控细胞床厚度的细胞封装设备 |
EP3911377A1 (fr) * | 2019-01-16 | 2021-11-24 | Boston Scientific Scimed Inc. | Dispositif d'administration cryothérapeutique |
WO2020243665A1 (fr) | 2019-05-31 | 2020-12-03 | W. L. Gore & Associates, Inc. | Composite à membrane biocompatible |
WO2020243663A1 (fr) | 2019-05-31 | 2020-12-03 | W. L. Gore & Associates, Inc. | Composite à membrane biocompatible |
CN114401752B (zh) | 2019-05-31 | 2023-04-04 | W.L.戈尔及同仁股份有限公司 | 具有受控氧扩散距离的细胞封装装置 |
WO2024073711A1 (fr) | 2022-09-30 | 2024-04-04 | W.L. Gore & Associates, Inc. | Construction de membrane implantable et dispositifs d'encapsulation l'incorporant |
Family Cites Families (77)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3993072A (en) * | 1974-08-28 | 1976-11-23 | Alza Corporation | Microporous drug delivery device |
GB1538810A (en) * | 1976-08-10 | 1979-01-24 | Sumitomo Electric Industries | Hydrophilic porous fluorocarbon structures and process for their production |
US4193138A (en) * | 1976-08-20 | 1980-03-18 | Sumitomo Electric Industries, Ltd. | Composite structure vascular prostheses |
US4743545A (en) * | 1984-08-09 | 1988-05-10 | Torobin Leonard B | Hollow porous microspheres containing biocatalyst |
US4409331A (en) * | 1979-03-28 | 1983-10-11 | Damon Corporation | Preparation of substances with encapsulated cells |
US4391909A (en) * | 1979-03-28 | 1983-07-05 | Damon Corporation | Microcapsules containing viable tissue cells |
US4353457A (en) * | 1979-04-24 | 1982-10-12 | Lerco Corporation | Airlift |
US4298002A (en) * | 1979-09-10 | 1981-11-03 | National Patent Development Corporation | Porous hydrophilic materials, chambers therefrom, and devices comprising such chambers and biologically active tissue and methods of preparation |
US4420589A (en) * | 1980-07-07 | 1983-12-13 | Stoy Vladimir A | Polymer composition including polyacrylonitrile polymers and process for preparing same |
US4353888A (en) * | 1980-12-23 | 1982-10-12 | Sefton Michael V | Encapsulation of live animal cells |
US4495288A (en) * | 1981-03-13 | 1985-01-22 | Damon Biotech, Inc. | Method of culturing anchorage dependent cells |
US4378016A (en) * | 1981-07-15 | 1983-03-29 | Biotek, Inc. | Artificial endocrine gland containing hormone-producing cells |
US4505266A (en) * | 1981-10-26 | 1985-03-19 | Massachusetts Institute Of Technology | Method of using a fibrous lattice |
EP0120061A4 (fr) * | 1982-09-29 | 1986-08-21 | Theodore E Spielberg | Organismes vivants encapsules programmes genetiquement produisant des substances therapeutiques. |
CA1196862A (fr) * | 1983-06-01 | 1985-11-19 | Anthony M.F. Sun | Microencapsulement de cellules et de tissus vivants |
US4806355A (en) * | 1983-06-06 | 1989-02-21 | Connaught Laboratories Limited | Microencapsulation of living tissue and cells |
US4631188A (en) * | 1983-08-31 | 1986-12-23 | S.K.Y. Polymers, Ltd. (Kingston Technologies) | Injectable physiologically-acceptable polymeric composition |
US4803168A (en) * | 1983-09-01 | 1989-02-07 | Damon Biotech, Inc. | Microencapsulation with polymers |
AU3542684A (en) * | 1983-11-15 | 1985-05-23 | Johnson & Johnson Corporation | Glycemia regulating implant |
US4663286A (en) * | 1984-02-13 | 1987-05-05 | Damon Biotech, Inc. | Encapsulation of materials |
US4686098A (en) * | 1984-05-14 | 1987-08-11 | Merck & Co., Inc. | Encapsulated mouse cells transformed with avian retrovirus-bovine growth hormone DNA, and a method of administering BGH in vivo |
CA1215922A (fr) * | 1984-05-25 | 1986-12-30 | Connaught Laboratories Limited | Microencapsulation de cellules et de tissus vivants |
US4722898A (en) * | 1985-04-29 | 1988-02-02 | Minnesota Mining And Manufacturing Company | Immobilization of biological cells in polytetrafluoroethylene matrix |
US4997443A (en) * | 1985-08-26 | 1991-03-05 | Hana Biologics, Inc. | Transplantable artificial tissue and process |
US4902295A (en) * | 1985-08-26 | 1990-02-20 | Hana Biologics, Inc. | Transplantable artificial tissue |
EP0213908A3 (fr) * | 1985-08-26 | 1989-03-22 | Hana Biologics, Inc. | Tissu artificiel transplantable et procédé |
US5218039A (en) * | 1987-04-28 | 1993-06-08 | Kingston Technologies, Inc. | Pan emulsion |
US4911717A (en) * | 1987-06-18 | 1990-03-27 | Gaskill Iii Harold V | Intravasular artificial organ |
US4942129A (en) * | 1987-07-28 | 1990-07-17 | Queen's University At Kingston | Multiple membrane microencapsulation |
US5786216A (en) * | 1987-11-17 | 1998-07-28 | Cytotherapeutics, Inc. | Inner-supported, biocompatible cell capsules |
US5418154A (en) * | 1987-11-17 | 1995-05-23 | Brown University Research Foundation | Method of preparing elongated seamless capsules containing biological material |
US5283187A (en) * | 1987-11-17 | 1994-02-01 | Brown University Research Foundation | Cell culture-containing tubular capsule produced by co-extrusion |
US5106627A (en) * | 1987-11-17 | 1992-04-21 | Brown University Research Foundation | Neurological therapy devices |
US5773286A (en) * | 1987-11-17 | 1998-06-30 | Cytotherapeutics, Inc. | Inner supported biocompatible cell capsules |
US4892538A (en) * | 1987-11-17 | 1990-01-09 | Brown University Research Foundation | In vivo delivery of neurotransmitters by implanted, encapsulated cells |
US5182111A (en) * | 1987-11-17 | 1993-01-26 | Boston University Research Foundation | In vivo delivery of active factors by co-cultured cell implants |
US5158881A (en) * | 1987-11-17 | 1992-10-27 | Brown University Research Foundation | Method and system for encapsulating cells in a tubular extrudate in separate cell compartments |
JPH037751A (ja) * | 1988-03-04 | 1991-01-14 | Kingston Technol Ltd Partnership | 新規ポリアクリロニトリル組成物およびその製造方法 |
US5081035A (en) * | 1988-04-18 | 1992-01-14 | The University Of Michigan | Bioreactor system |
US4941812A (en) * | 1988-05-10 | 1990-07-17 | E. I. Du Pont De Nemours And Company | Spinneret for production of a hollow filament within a hollow filament composite fiber having spacing means |
FR2634382B1 (fr) * | 1988-07-21 | 1990-10-26 | Applic Techn Photoniques | Pancreas artificiel |
WO1990001498A1 (fr) * | 1988-08-12 | 1990-02-22 | Cell Biotech, Inc. | Procede de purification des cellules des ilots; anticorps monoclonaux des cellules des ilots et des acini; leur procede de production et d'utilisation |
GB8820493D0 (en) * | 1988-08-30 | 1988-09-28 | Secretary Trade Ind Brit | Membrane bioreactor |
US5345587A (en) * | 1988-09-14 | 1994-09-06 | Digital Equipment Corporation | Extensible entity management system including a dispatching kernel and modules which independently interpret and execute commands |
CA1323959C (fr) * | 1988-09-16 | 1993-11-09 | Andreas F. Von Recum | Implant de tissu mou a texture superficielle de l'ordre du micrometre pour optimiser l'ancrage |
US5068195A (en) * | 1988-11-02 | 1991-11-26 | Du Pont Merck Pharmaceutical Company | Dot matrix membrane cell expansion and maintenance vessel |
US5011486A (en) * | 1988-11-18 | 1991-04-30 | Brown University Research Foundation | Composite nerve guidance channels |
US5017490A (en) * | 1989-03-10 | 1991-05-21 | Baxter International Inc. | Method for in vitro reproduction and growth of cells in culture medium |
AU636346B2 (en) * | 1989-04-25 | 1993-04-29 | Children's Hospital | Method for implanting large volumes of cells on polymeric matrices |
DK0478671T3 (da) * | 1989-06-21 | 1993-10-18 | Univ Brown Res Found | Neurologisk terapeutisk anordning |
US5030255A (en) * | 1989-06-29 | 1991-07-09 | Texaco Inc. | Fluid separator |
WO1991000119A1 (fr) * | 1989-06-30 | 1991-01-10 | Baxter International Inc. | Dispositif implantable |
US5116494A (en) * | 1989-08-25 | 1992-05-26 | W. R. Grace & Co.-Conn. | Artificial pancreatic perfusion device with temperature sensitive matrix |
US5002661A (en) * | 1989-08-25 | 1991-03-26 | W. R. Grace & Co.-Conn. | Artificial pancreatic perfusion device |
US5116493A (en) * | 1989-08-25 | 1992-05-26 | W. R. Grace & Co.-Conn. | Artificial pancreatic perfusion device with reseedable matrix |
US5100392A (en) * | 1989-12-08 | 1992-03-31 | Biosynthesis, Inc. | Implantable device for administration of drugs or other liquid solutions |
WO1991010470A1 (fr) * | 1990-01-08 | 1991-07-25 | Brown University Research Foundation | Dispositifs et procedes d'apport ameliore de facteurs actifs |
US4969705A (en) * | 1990-01-19 | 1990-11-13 | Kingston Technologies, L.P. | Memory polymer multiple cavity fiber splicer |
US5084350A (en) * | 1990-02-16 | 1992-01-28 | The Royal Institution For The Advance Of Learning (Mcgill University) | Method for encapsulating biologically active material including cells |
US5256418A (en) * | 1990-04-06 | 1993-10-26 | Organogenesis, Inc. | Collagen constructs |
US5344454A (en) * | 1991-07-24 | 1994-09-06 | Baxter International Inc. | Closed porous chambers for implanting tissue in a host |
CA2070816A1 (fr) * | 1990-10-31 | 1992-05-01 | James H. Brauker | Implant favorisant la vascularisation |
US5314471A (en) * | 1991-07-24 | 1994-05-24 | Baxter International Inc. | Tissue inplant systems and methods for sustaining viable high cell densities within a host |
DE4108772A1 (de) * | 1991-03-18 | 1992-09-24 | Inst Textil & Faserforschung | Implantierbares biohybrides organ |
DE69221484T2 (de) * | 1991-04-25 | 1998-02-19 | Univ Brown Res Found | Implantierbare, biokompatible immunisolator-trägersubstanz zum abgeben ausgesuchter, therapeutischer produkte |
US5453278A (en) * | 1991-07-24 | 1995-09-26 | Baxter International Inc. | Laminated barriers for tissue implants |
US5116753A (en) * | 1991-07-30 | 1992-05-26 | The Salk Institute For Biological Studies | Maintenance of pancreatic islets |
DE69219613T2 (de) * | 1991-10-30 | 1997-11-27 | Childrens Medical Center | Vorvaskularisierte polymerimplantate für organtransplantation |
EP0676935B1 (fr) * | 1992-04-01 | 2001-11-07 | BAXTER INTERNATIONAL INC. (a Delaware corporation) | Systemes d'implantation de tissus angiogeniques |
WO1993022427A1 (fr) * | 1992-04-24 | 1993-11-11 | Somatix Therapy Corporation | Procede de culture de cellules viables et procede de regulation du niveau d'un compose dans un fluide corporel |
WO1993021902A1 (fr) * | 1992-04-24 | 1993-11-11 | Somatix Therapy Corporation | Dispositif implantable therapeutique et biocompatible |
US5209850A (en) * | 1992-06-19 | 1993-05-11 | W. L. Gore & Associates, Inc. | Hydrophilic membranes |
JPH08502166A (ja) * | 1992-09-28 | 1996-03-12 | ブラウン ユニヴァーシティ リサーチ ファンデーション | カプセル化細胞用キトサンマトリックス |
AU688776B2 (en) * | 1993-06-23 | 1998-03-19 | Brown University Research Foundation | Method and apparatus for sealing implantable, membrane encapsulation devices |
ATE183078T1 (de) * | 1993-08-10 | 1999-08-15 | Gore & Ass | Zelleinkapselungsvorrichtung |
US5352511A (en) * | 1993-11-15 | 1994-10-04 | W. L. Gore & Associates, Onc. | Hydrophilic compositions with increased thermal resistance |
JPH08507949A (ja) * | 1994-01-11 | 1996-08-27 | バクスター、インターナショナル、インコーポレイテッド | ポート付きの組織埋め込みシステム及びその使用方法 |
-
1996
- 1996-08-23 WO PCT/US1996/013547 patent/WO1997010807A1/fr active Application Filing
- 1996-08-23 AU AU68546/96A patent/AU6854696A/en not_active Abandoned
- 1996-09-18 IT IT96MI001913A patent/IT1284549B1/it active IP Right Grant
- 1996-09-19 FR FR9611420A patent/FR2739028B1/fr not_active Expired - Lifetime
- 1996-09-20 NL NL1004082A patent/NL1004082C2/nl not_active IP Right Cessation
-
1997
- 1997-05-21 US US08/859,946 patent/US5902745A/en not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
NL1004082A1 (nl) | 1997-03-25 |
IT1284549B1 (it) | 1998-05-21 |
FR2739028A1 (fr) | 1997-03-28 |
ITMI961913A1 (it) | 1998-03-18 |
WO1997010807A1 (fr) | 1997-03-27 |
US5902745A (en) | 1999-05-11 |
NL1004082C2 (nl) | 1998-04-10 |
AU6854696A (en) | 1997-04-09 |
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