FR2625503A1 - Derives de dioxazocine, leur procede de preparation et compositions pharmaceutiques les contenant - Google Patents

Derives de dioxazocine, leur procede de preparation et compositions pharmaceutiques les contenant Download PDF

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Publication number
FR2625503A1
FR2625503A1 FR8817385A FR8817385A FR2625503A1 FR 2625503 A1 FR2625503 A1 FR 2625503A1 FR 8817385 A FR8817385 A FR 8817385A FR 8817385 A FR8817385 A FR 8817385A FR 2625503 A1 FR2625503 A1 FR 2625503A1
Authority
FR
France
Prior art keywords
formula
carbon atoms
alkyl group
compound
acid addition
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
FR8817385A
Other languages
English (en)
French (fr)
Inventor
A Eszlo
A E Ro
A Ezsa
Lujza Peto
A Cz
Eniko
A Sziri Ma
A Erton Fekete Ma
A Eria Szecsey Ga
A Ebor Gigler
Istva
A En Gacsa
A Elyi
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Egyt Gyogyszervegyeszeti Gyar
Egis Gyógyszergyár Zrt
Original Assignee
Egyt Gyogyszervegyeszeti Gyar
Egis Gyógyszergyár Zrt
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Egyt Gyogyszervegyeszeti Gyar, Egis Gyógyszergyár Zrt filed Critical Egyt Gyogyszervegyeszeti Gyar
Publication of FR2625503A1 publication Critical patent/FR2625503A1/fr
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D273/00—Heterocyclic compounds containing rings having nitrogen and oxygen atoms as the only ring hetero atoms, not provided for by groups C07D261/00 - C07D271/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D273/00—Heterocyclic compounds containing rings having nitrogen and oxygen atoms as the only ring hetero atoms, not provided for by groups C07D261/00 - C07D271/00
    • C07D273/01—Heterocyclic compounds containing rings having nitrogen and oxygen atoms as the only ring hetero atoms, not provided for by groups C07D261/00 - C07D271/00 having one nitrogen atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A61P21/02—Muscle relaxants, e.g. for tetanus or cramps
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P23/00—Anaesthetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P23/00—Anaesthetics
    • A61P23/02—Local anaesthetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/22—Anxiolytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/26—Psychostimulants, e.g. nicotine, cocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/06—Antiarrhythmics

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Anesthesiology (AREA)
  • Pain & Pain Management (AREA)
  • Psychiatry (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Plural Heterocyclic Compounds (AREA)
FR8817385A 1987-12-31 1988-12-29 Derives de dioxazocine, leur procede de preparation et compositions pharmaceutiques les contenant Withdrawn FR2625503A1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
HU876170A HU201318B (en) 1987-12-31 1987-12-31 Process for producing dioxazoline derivatives and pharmaceutical compositions comprising same

Publications (1)

Publication Number Publication Date
FR2625503A1 true FR2625503A1 (fr) 1989-07-07

Family

ID=10971300

Family Applications (1)

Application Number Title Priority Date Filing Date
FR8817385A Withdrawn FR2625503A1 (fr) 1987-12-31 1988-12-29 Derives de dioxazocine, leur procede de preparation et compositions pharmaceutiques les contenant

Country Status (22)

Country Link
US (1) US4965259A (enExample)
JP (1) JPH01213273A (enExample)
KR (1) KR890009896A (enExample)
CN (1) CN1034926A (enExample)
AU (1) AU610678B2 (enExample)
BE (1) BE1002696A3 (enExample)
CH (1) CH677669A5 (enExample)
CS (1) CS272247B2 (enExample)
DE (1) DE3844394A1 (enExample)
DK (1) DK733688A (enExample)
ES (1) ES2010855A6 (enExample)
FI (1) FI886065A7 (enExample)
FR (1) FR2625503A1 (enExample)
GB (1) GB2213480B (enExample)
GR (1) GR1000098B (enExample)
HU (1) HU201318B (enExample)
IT (1) IT1227920B (enExample)
NL (1) NL8803218A (enExample)
PL (1) PL154357B1 (enExample)
SE (1) SE8804696L (enExample)
SU (1) SU1641190A3 (enExample)
YU (1) YU240088A (enExample)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0423870A1 (en) * 1989-10-20 1991-04-24 Akzo Nobel N.V. Dibenzodioxazecine and dibenzodioxaazacycloundecine derivatives

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HU198194B (en) * 1986-12-30 1989-08-28 Egyt Gyogyszervegyeszeti Gyar Process for production of new derivatives of dioxazocin and medical compositions containing them
RU2178790C2 (ru) * 1995-09-19 2002-01-27 Ново Нордиск А/С Производные дибензо[d, g][1,3]диоксоцина и дибензо-[d,g][1,3,6]диоксазоцина, способ их получения, фармацевтическая композиция на их основе и способ лечения нейрогенного воспаления, нейропатии и ревматоидного артрита

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2001980A (en) * 1977-08-02 1979-02-14 Egyt Gyogyszervegyeszeti Gyar Dioxazocine derivatives their preparation and compositions containing them

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL108827C (enExample) * 1956-04-09
US3258459A (en) * 1962-08-30 1966-06-28 Squibb & Sons Inc Method for the preparation of n-monosubstituted-secondary aminoalkyl derivatives of polycyclic compounds
US3803143A (en) * 1969-09-08 1974-04-09 Eisai Co Ltd 6-amino alkylene 6,7-dihydro-5h-dibenzo (b,g),(1,5)thiazocines
GB1464431A (en) * 1974-03-25 1977-02-16 Roche Products Ltd Indolobenzazepine derivatives and a process for the manufacture thereof
HU195491B (en) * 1985-12-20 1988-05-30 Egyt Gyogyszervegyeszeti Gyar Process for production of optically active 2-chlor-12-/3-/dimethil-amin/-2-methil-prophil/-12h-dibenzol /d,g/ /1,3,6/-diaxazocine and medical compositions containing such compounds
HU198194B (en) * 1986-12-30 1989-08-28 Egyt Gyogyszervegyeszeti Gyar Process for production of new derivatives of dioxazocin and medical compositions containing them

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2001980A (en) * 1977-08-02 1979-02-14 Egyt Gyogyszervegyeszeti Gyar Dioxazocine derivatives their preparation and compositions containing them

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
ARZNEIMITTEL-FORSCHUNG, vol. 26, no. 6, juin 1976, pages 1036-1039, Aulendorf, DE; W. HAEFELY et al.: "Interaction of psychotropic agents with central neurotransmitters as revealed by their effects on PGO waves in the cat" *

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0423870A1 (en) * 1989-10-20 1991-04-24 Akzo Nobel N.V. Dibenzodioxazecine and dibenzodioxaazacycloundecine derivatives
US5106839A (en) * 1989-10-20 1992-04-21 Akzo N.V. Dibenzodioxazecine and dibenzodioxaazacycloundecine derivatives

Also Published As

Publication number Publication date
PL276891A1 (en) 1989-12-27
HUT50144A (en) 1989-12-28
NL8803218A (nl) 1989-07-17
IT8823183A0 (it) 1988-12-30
PL154357B1 (en) 1991-08-30
SE8804696D0 (sv) 1988-12-29
CS272247B2 (en) 1991-01-15
AU610678B2 (en) 1991-05-23
DE3844394A1 (de) 1989-07-13
SE8804696L (sv) 1989-07-01
CN1034926A (zh) 1989-08-23
KR890009896A (ko) 1989-08-04
DK733688A (da) 1989-07-01
YU240088A (en) 1990-02-28
FI886065A7 (fi) 1989-07-01
IT1227920B (it) 1991-05-14
GR1000098B (el) 1991-03-15
US4965259A (en) 1990-10-23
JPH01213273A (ja) 1989-08-28
HU201318B (en) 1990-10-28
AU2763788A (en) 1989-07-06
CS910288A2 (en) 1990-03-14
CH677669A5 (enExample) 1991-06-14
ES2010855A6 (es) 1989-12-01
GB2213480B (en) 1991-06-26
GB2213480A (en) 1989-08-16
SU1641190A3 (ru) 1991-04-07
BE1002696A3 (fr) 1991-05-07
GB8830416D0 (en) 1989-03-01
DK733688D0 (da) 1988-12-30

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