FR2621915B1 - Produits chimiques intermediaires utilisables pour la preparation de certains agents anti-histaminiques h2 et leur procede de preparation - Google Patents

Produits chimiques intermediaires utilisables pour la preparation de certains agents anti-histaminiques h2 et leur procede de preparation

Info

Publication number
FR2621915B1
FR2621915B1 FR888806479A FR8806479A FR2621915B1 FR 2621915 B1 FR2621915 B1 FR 2621915B1 FR 888806479 A FR888806479 A FR 888806479A FR 8806479 A FR8806479 A FR 8806479A FR 2621915 B1 FR2621915 B1 FR 2621915B1
Authority
FR
France
Prior art keywords
preparation
certain
preparation process
intermediate chemicals
histaminic agents
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
FR888806479A
Other languages
English (en)
Other versions
FR2621915A1 (fr
Inventor
Aldo A Algieri
Robert F Farney
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bristol Myers Co
Original Assignee
Bristol Myers Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bristol Myers Co filed Critical Bristol Myers Co
Publication of FR2621915A1 publication Critical patent/FR2621915A1/fr
Application granted granted Critical
Publication of FR2621915B1 publication Critical patent/FR2621915B1/fr
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/08—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
    • C07D295/096—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms separated by carbocyclic rings or by carbon chains interrupted by carbocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C225/00—Compounds containing amino groups and doubly—bound oxygen atoms bound to the same carbon skeleton, at least one of the doubly—bound oxygen atoms not being part of a —CHO group, e.g. amino ketones
    • C07C225/20—Compounds containing amino groups and doubly—bound oxygen atoms bound to the same carbon skeleton, at least one of the doubly—bound oxygen atoms not being part of a —CHO group, e.g. amino ketones having amino groups bound to carbon atoms of rings other than six-membered aromatic rings of the carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
    • C07D317/10—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings
    • C07D317/14—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D317/18—Radicals substituted by singly bound oxygen or sulfur atoms
    • C07D317/22—Radicals substituted by singly bound oxygen or sulfur atoms etherified
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00—Systems containing only non-condensed rings
    • C07C2601/04—Systems containing only non-condensed rings with a four-membered ring

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Plural Heterocyclic Compounds (AREA)
FR888806479A 1987-05-14 1988-05-13 Produits chimiques intermediaires utilisables pour la preparation de certains agents anti-histaminiques h2 et leur procede de preparation Expired - Fee Related FR2621915B1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US5045987A 1987-05-14 1987-05-14
US07/174,444 US4927968A (en) 1987-05-14 1988-04-11 Chemical intermediates and process

Publications (2)

Publication Number Publication Date
FR2621915A1 FR2621915A1 (fr) 1989-04-21
FR2621915B1 true FR2621915B1 (fr) 1990-11-16

Family

ID=26728293

Family Applications (2)

Application Number Title Priority Date Filing Date
FR888806479A Expired - Fee Related FR2621915B1 (fr) 1987-05-14 1988-05-13 Produits chimiques intermediaires utilisables pour la preparation de certains agents anti-histaminiques h2 et leur procede de preparation
FR888813779A Expired - Fee Related FR2628738B1 (fr) 1987-05-14 1988-10-20 Produits chimiques intermediaires utilisables pour la preparation de certains agents anti-histaminiques h2

Family Applications After (1)

Application Number Title Priority Date Filing Date
FR888813779A Expired - Fee Related FR2628738B1 (fr) 1987-05-14 1988-10-20 Produits chimiques intermediaires utilisables pour la preparation de certains agents anti-histaminiques h2

Country Status (16)

Country Link
US (1) US4927968A (fr)
JP (2) JPS6419050A (fr)
AT (1) AT395973B (fr)
BE (1) BE1002037A3 (fr)
CH (1) CH674983A5 (fr)
CY (2) CY1818A (fr)
DE (1) DE3816634A1 (fr)
ES (1) ES2009275A6 (fr)
FR (2) FR2621915B1 (fr)
GB (2) GB2204584B (fr)
GR (1) GR1000504B (fr)
HK (2) HK23395A (fr)
IE (1) IE61393B1 (fr)
IT (1) IT1217599B (fr)
NL (1) NL8801240A (fr)
SE (2) SE8801798L (fr)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2241235B (en) * 1987-05-14 1992-01-29 Bristol Myers Co Cyclobutene compound
US4988828A (en) * 1987-11-27 1991-01-29 Fujirebio Kabushiki Kaisha Phenoxypropyl derivatives
JPH03206068A (ja) * 1990-01-06 1991-09-09 Ikeda Mohandou:Kk シクロブテン―１，２―ジオン誘導体
KR100200115B1 (ko) * 1994-04-25 1999-06-15 정몽규 실린더 헤드의 연소실 구조
JP2005264951A (ja) * 2005-05-09 2005-09-29 Tatsuto Noda 加速ポンプジェット

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1518660A1 (de) * 1965-07-09 1969-08-14 Huels Chemische Werke Ag Verfahren zur Herstellung aminosubstituierter Dioxocyclobutene
GB1563090A (en) * 1975-07-31 1980-03-19 Smith Kline French Lab Cyclobutene-diones
GB2023133B (en) * 1978-04-26 1982-09-08 Glaxo Group Ltd Heterocyclic derivatives
US4390701A (en) * 1981-05-18 1983-06-28 Bristol-Myers Company 1-Amino-2-[3-(3-piperidinomethylphenoxy)propylamino]cyclobutene-3,4-dione
US4395553A (en) * 1981-05-18 1983-07-26 Bristol-Myers Company Chemical compounds
US4522943A (en) * 1981-05-18 1985-06-11 Bristol-Myers Company Chemical compounds
US4526973A (en) * 1981-05-18 1985-07-02 Bristol-Myers Company Chemical compounds
US4466970A (en) * 1982-10-02 1984-08-21 Smith Kline & French Laboratories Limited Dioxocyclobutene compounds

Also Published As

Publication number Publication date
CY1818A (en) 1995-10-20
NL8801240A (nl) 1988-12-01
SE9300455A0 (sv) 1993-02-11
JPH0512337B2 (fr) 1993-02-17
GR1000504B (el) 1992-07-30
ATA125688A (de) 1992-09-15
BE1002037A3 (fr) 1990-05-29
JPH0660135B2 (ja) 1994-08-10
HK23395A (en) 1995-03-03
AT395973B (de) 1993-04-26
SE9300455D0 (sv) 1993-02-11
FR2621915A1 (fr) 1989-04-21
GB2204584B (en) 1992-01-29
FR2628738B1 (fr) 1991-11-29
GR880100311A (en) 1989-02-23
CY1819A (en) 1995-10-20
SE8801798D0 (sv) 1988-05-11
IT8820584A0 (it) 1988-05-13
CH674983A5 (fr) 1990-08-15
GB8811456D0 (en) 1988-06-15
HK23495A (en) 1995-03-03
JPH05238998A (ja) 1993-09-17
SE8801798L (sv) 1988-11-15
JPS6419050A (en) 1989-01-23
GB2204584A (en) 1988-11-16
IT1217599B (it) 1990-03-30
US4927968A (en) 1990-05-22
IE61393B1 (en) 1994-11-02
GB9025856D0 (en) 1991-01-09
FR2628738A1 (fr) 1989-09-22
DE3816634A1 (de) 1988-11-24
ES2009275A6 (es) 1989-09-16
IE881459L (en) 1988-11-14

Similar Documents

Publication Publication Date Title
PT87492A (pt) Process for the preparation of benzo ]b" pyrrans and pyranopyridines and pharmaceutical compositions containing them
SK944886A3 (en) Melting and refining method of material used in the glass production and davice for carrying out this method
HUT68635A (en) Tissue moisturizing composition and process for production of this
PL275089A1 (en) Method of obtaining novel pharmaceutical compositions
IL82231A0 (en) 1-hydroxy-2-pyridones,process for their preparation,and pharmaceutical compositions which contain them and intermediates formed in the preparation of the 1-hydroxy-2-pyridones
FR2624852B1 (fr) Procede de preparation d'une surface d'une structure refractaire et composition de particules destinee a ce procede
BE885249A (fr) Monture pour pierres precieuses et procede d'emploi de celli-ci
FR2611208B1 (fr) Procede pour la preparation de polyorganosilazanes et de materiaux ceramiques en derivant
IT8149520A0 (it) Procedimento per la preparazione di sospensioni stabili e non gelificabili in particolare per la produzione di detersivi in granuli
PT87470A (pt) Process for the preparation of novel substituted benzamides and of pharmaceutical compositions containing the same
IT1224581B (it) Procedimento ed apparecchio per la fabbricazione di fogli di cartone di fibra
MA21413A1 (fr) Nouveau procede de preparation d'alcoxy-guanine
HUT62193A (en) Process for producing pharmaceutical composition improving the effect of photoageing
FR2621915B1 (fr) Produits chimiques intermediaires utilisables pour la preparation de certains agents anti-histaminiques h2 et leur procede de preparation
FR2612775B1 (fr) Compositions pour la prevention et le traitement de la degenerescence cutanee
IT8947842A0 (it) Procedimento per la produzione di r(+) amminocarnitina e s(-) amminocarnitina
FR2612373B1 (fr) Compositions dietetiques et procede pour leur preparation
PT84933B (fr) Procede de preparation de cyclodepsipeptides et compositions pharmaceutiques qui les contiennent
EP0284200A3 (en) Method for treatment of fibrous materials
PT84184A (pt) Process for the preparation of 8 alpha-acylaminoergolines and of pharmaceutical compositions containing them
HUT46689A (en) Process for producing benzimidazole derovatives and pharmaceutical compositions containing them
FR2605498B1 (fr) Procede et dispositif pour la fabrication de gnocchis et produits similaires
FR2640140B1 (fr) Compositions pour le traitement de phlebectasies et leur procede de preparation
FR2549726B1 (fr) Facteurs augmentant la formation d'anticorps humains et procede pour leur preparation
HU908403D0 (en) Process for the production of amino-pyridinyl-methanol- and amino-methyl-pyridine-amin derivatives and medical compositions containing them as active agents

Legal Events

Date Code Title Description
CD Change of name or company name
ST Notification of lapse
ST Notification of lapse