FR2525223B1 - Nouveaux acides diphosphoniques, leurs sels, leur procede de preparation et leur application en therapeutique - Google Patents

Nouveaux acides diphosphoniques, leurs sels, leur procede de preparation et leur application en therapeutique

Info

Publication number
FR2525223B1
FR2525223B1 FR8305858A FR8305858A FR2525223B1 FR 2525223 B1 FR2525223 B1 FR 2525223B1 FR 8305858 A FR8305858 A FR 8305858A FR 8305858 A FR8305858 A FR 8305858A FR 2525223 B1 FR2525223 B1 FR 2525223B1
Authority
FR
France
Prior art keywords
therapeutics
salts
application
preparation process
diphosphonic acids
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
FR8305858A
Other languages
English (en)
Other versions
FR2525223A1 (fr
Inventor
Sergio Rosini
Giorgio Staibano
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Istituto Gentili SpA
Original Assignee
Istituto Gentili SpA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=11171970&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=FR2525223(B1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Istituto Gentili SpA filed Critical Istituto Gentili SpA
Publication of FR2525223A1 publication Critical patent/FR2525223A1/fr
Application granted granted Critical
Publication of FR2525223B1 publication Critical patent/FR2525223B1/fr
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/28—Phosphorus compounds with one or more P—C bonds
    • C07F9/38—Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)]
    • C07F9/3804—Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)] not used, see subgroups
    • C07F9/3839—Polyphosphonic acids
    • C07F9/3873—Polyphosphonic acids containing nitrogen substituent, e.g. N.....H or N-hydrocarbon group which can be substituted by halogen or nitro(so), N.....O, N.....S, N.....C(=X)- (X =O, S), N.....N, N...C(=X)...N (X =O, S)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/28—Phosphorus compounds with one or more P—C bonds
    • C07F9/38—Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)]
    • C07F9/3804—Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)] not used, see subgroups
    • C07F9/3839—Polyphosphonic acids
    • C07F9/3856—Polyphosphonic acids containing halogen or nitro(so) substituents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Diabetes (AREA)
  • Urology & Nephrology (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
FR8305858A 1982-04-15 1983-04-11 Nouveaux acides diphosphoniques, leurs sels, leur procede de preparation et leur application en therapeutique Expired FR2525223B1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT8220781A IT1201087B (it) 1982-04-15 1982-04-15 Bifosfonati farmacologicamente attivi,procedimento per la loro preparazione e relative composizioni farmaceutiche

Publications (2)

Publication Number Publication Date
FR2525223A1 FR2525223A1 (fr) 1983-10-21
FR2525223B1 true FR2525223B1 (fr) 1986-04-25

Family

ID=11171970

Family Applications (1)

Application Number Title Priority Date Filing Date
FR8305858A Expired FR2525223B1 (fr) 1982-04-15 1983-04-11 Nouveaux acides diphosphoniques, leurs sels, leur procede de preparation et leur application en therapeutique

Country Status (12)

Country Link
US (1) US4621077A (fr)
JP (1) JPS58189193A (fr)
BE (1) BE896453A (fr)
CH (1) CH661437A5 (fr)
FR (1) FR2525223B1 (fr)
GB (1) GB2118042B (fr)
HK (1) HK79390A (fr)
IT (1) IT1201087B (fr)
LU (2) LU84746A1 (fr)
MX (1) MX9203428A (fr)
NL (5) NL192562C (fr)
SE (1) SE463239B (fr)

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DE3623397A1 (de) * 1986-07-11 1988-01-14 Boehringer Mannheim Gmbh Neue diphosphonsaeurederivate, verfahren zu deren herstellung und diese verbindungen enthaltende arzneimittel
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SE8302130L (sv) 1983-10-16
NL192562C (nl) 1997-10-03
SE8302130D0 (sv) 1983-04-15
LU88714I2 (fr) 1996-08-23
NL980005I1 (nl) 1998-04-01
NL8301324A (nl) 1983-11-01
NL980004I1 (nl) 1998-04-01
GB8308791D0 (en) 1983-05-11
GB2118042B (en) 1986-01-15
JPS58189193A (ja) 1983-11-04
CH661437A5 (it) 1987-07-31
FR2525223A1 (fr) 1983-10-21
IT8220781A0 (it) 1982-04-15
US4621077A (en) 1986-11-04
MX9203428A (es) 1992-07-01
NL980010I1 (nl) 1998-05-06
NL192562B (nl) 1997-06-02
NL970038I2 (nl) 2000-11-01
LU84746A1 (fr) 1983-11-17
HK79390A (en) 1990-10-12
JPH0213645B2 (fr) 1990-04-04
NL970038I1 (nl) 1998-01-05
SE463239B (sv) 1990-10-29
BE896453A (fr) 1983-08-01
IT1201087B (it) 1989-01-27
GB2118042A (en) 1983-10-26

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