FR2525223B1 - NOVEL DIPHOSPHONIC ACIDS, THEIR SALTS, THEIR PREPARATION PROCESS AND THEIR APPLICATION IN THERAPEUTICS - Google Patents
NOVEL DIPHOSPHONIC ACIDS, THEIR SALTS, THEIR PREPARATION PROCESS AND THEIR APPLICATION IN THERAPEUTICSInfo
- Publication number
- FR2525223B1 FR2525223B1 FR8305858A FR8305858A FR2525223B1 FR 2525223 B1 FR2525223 B1 FR 2525223B1 FR 8305858 A FR8305858 A FR 8305858A FR 8305858 A FR8305858 A FR 8305858A FR 2525223 B1 FR2525223 B1 FR 2525223B1
- Authority
- FR
- France
- Prior art keywords
- therapeutics
- salts
- application
- preparation process
- diphosphonic acids
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 239000002253 acid Substances 0.000 title 1
- 150000007513 acids Chemical class 0.000 title 1
- 239000003814 drug Substances 0.000 title 1
- 238000002360 preparation method Methods 0.000 title 1
- 150000003839 salts Chemical class 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic System
- C07F9/02—Phosphorus compounds
- C07F9/28—Phosphorus compounds with one or more P—C bonds
- C07F9/38—Phosphonic acids RP(=O)(OH)2; Thiophosphonic acids, i.e. RP(=X)(XH)2 (X = S, Se)
- C07F9/3804—Phosphonic acids RP(=O)(OH)2; Thiophosphonic acids, i.e. RP(=X)(XH)2 (X = S, Se) not used, see subgroups
- C07F9/3839—Polyphosphonic acids
- C07F9/3873—Polyphosphonic acids containing nitrogen substituent, e.g. N.....H or N-hydrocarbon group which can be substituted by halogen or nitro(so), N.....O, N.....S, N.....C(=X)- (X =O, S), N.....N, N...C(=X)...N (X =O, S)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic System
- C07F9/02—Phosphorus compounds
- C07F9/28—Phosphorus compounds with one or more P—C bonds
- C07F9/38—Phosphonic acids RP(=O)(OH)2; Thiophosphonic acids, i.e. RP(=X)(XH)2 (X = S, Se)
- C07F9/3804—Phosphonic acids RP(=O)(OH)2; Thiophosphonic acids, i.e. RP(=X)(XH)2 (X = S, Se) not used, see subgroups
- C07F9/3839—Polyphosphonic acids
- C07F9/3856—Polyphosphonic acids containing halogen or nitro(so) substituents
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IT8220781A IT1201087B (en) | 1982-04-15 | 1982-04-15 | PHARMACOLOGICALLY ACTIVE BIPPHOSPHONES, PROCEDURE FOR THEIR PREPARATION AND RELATED PHARMACEUTICAL COMPOSITIONS |
Publications (2)
Publication Number | Publication Date |
---|---|
FR2525223A1 FR2525223A1 (en) | 1983-10-21 |
FR2525223B1 true FR2525223B1 (en) | 1986-04-25 |
Family
ID=11171970
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
FR8305858A Expired FR2525223B1 (en) | 1982-04-15 | 1983-04-11 | NOVEL DIPHOSPHONIC ACIDS, THEIR SALTS, THEIR PREPARATION PROCESS AND THEIR APPLICATION IN THERAPEUTICS |
Country Status (12)
Country | Link |
---|---|
US (1) | US4621077A (en) |
JP (1) | JPS58189193A (en) |
BE (1) | BE896453A (en) |
CH (1) | CH661437A5 (en) |
FR (1) | FR2525223B1 (en) |
GB (1) | GB2118042B (en) |
HK (1) | HK79390A (en) |
IT (1) | IT1201087B (en) |
LU (2) | LU84746A1 (en) |
MX (1) | MX9203428A (en) |
NL (5) | NL192562C (en) |
SE (1) | SE463239B (en) |
Families Citing this family (111)
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DE3540150A1 (en) * | 1985-11-13 | 1987-05-14 | Boehringer Mannheim Gmbh | NEW DIPHOSPHONIC ACID DERIVATIVES, METHOD FOR THE PRODUCTION THEREOF AND MEDICINAL PRODUCTS CONTAINING THESE COMPOUNDS |
DE3623397A1 (en) * | 1986-07-11 | 1988-01-14 | Boehringer Mannheim Gmbh | NEW DIPHOSPHONIC ACID DERIVATIVES, METHOD FOR THE PRODUCTION THEREOF AND MEDICINAL PRODUCTS CONTAINING THESE COMPOUNDS |
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US4264582A (en) * | 1978-07-31 | 1981-04-28 | The Procter & Gamble Company | Isobutylphenylacetate anti-inflammatory composition |
US4282214A (en) * | 1978-07-31 | 1981-08-04 | The Procter & Gamble Company | Phenylacetate anti-inflammatory composition |
US4254114A (en) * | 1979-01-02 | 1981-03-03 | The Proctor & Gamble Company | Control of pyrophosphate microorganisms with organophosphonates |
GB2043072B (en) * | 1979-02-13 | 1983-11-23 | Symphar Sa | Diphosphonate compounds |
GB2076889B (en) * | 1980-03-12 | 1983-10-26 | Cadbury Schweppes Transport | Feeding fuel and water emulsion i c engines |
DE3016289A1 (en) * | 1980-04-28 | 1981-10-29 | Henkel KGaA, 4000 Düsseldorf | METHOD FOR PRODUCING OMEGA-AMINO-1-HYDROXYALKYLIDEN-1,1-BIS-PHOSPHONIC ACIDS |
GB2079285B (en) * | 1980-07-09 | 1984-05-23 | Symphar Sa | Dipthosphonate derivatives and pahrmaceutical compositions containing them |
GB2082585A (en) * | 1980-08-27 | 1982-03-10 | Vysoka Skola Chem Tech | 6-amino-1-hydroxyhexylidene diphosphonic acid, salts thereof and a method of producing the acid and salts. |
JPS5759900A (en) * | 1980-09-29 | 1982-04-10 | Vysoka Skola Chem Tech | 6-amino-1-hydroxyhexylidene diphosphonic acid |
BE890453A (en) * | 1980-10-07 | 1982-03-22 | Procter & Gamble | PROCESS FOR INHIBITING TUMOR CELL METASTASES |
US4330530A (en) * | 1980-12-22 | 1982-05-18 | The Procter & Gamble Company | Anti-arthritic compositions and method using gold salts and organophosphonates |
IT1194748B (en) * | 1981-02-12 | 1988-09-28 | Gentili Ist Spa | PHARMACEUTICAL COMPOSITIONS FOR THE TREATMENT OF OSTEOPATHIES |
-
1982
- 1982-04-15 IT IT8220781A patent/IT1201087B/en active Protection Beyond IP Right Term
-
1983
- 1983-03-25 CH CH1654/83A patent/CH661437A5/en not_active IP Right Cessation
- 1983-03-30 GB GB08308791A patent/GB2118042B/en not_active Expired
- 1983-04-11 FR FR8305858A patent/FR2525223B1/en not_active Expired
- 1983-04-13 JP JP58065160A patent/JPS58189193A/en active Granted
- 1983-04-13 LU LU84746A patent/LU84746A1/en active Protection Beyond IP Right Term
- 1983-04-13 LU LU88714C patent/LU88714I2/en unknown
- 1983-04-14 BE BE2/60071A patent/BE896453A/en not_active IP Right Cessation
- 1983-04-15 NL NL8301324A patent/NL192562C/en active Protection Beyond IP Right Term
- 1983-04-15 SE SE8302130A patent/SE463239B/en not_active IP Right Cessation
-
1984
- 1984-06-08 US US06/618,578 patent/US4621077A/en not_active Expired - Lifetime
-
1990
- 1990-10-03 HK HK793/90A patent/HK79390A/en not_active IP Right Cessation
-
1992
- 1992-06-25 MX MX9203428A patent/MX9203428A/en unknown
-
1997
- 1997-11-07 NL NL970038C patent/NL970038I2/en unknown
-
1998
- 1998-01-09 NL NL980004C patent/NL980004I1/en unknown
- 1998-01-26 NL NL980005C patent/NL980005I1/en unknown
- 1998-03-03 NL NL980010C patent/NL980010I1/en unknown
Also Published As
Publication number | Publication date |
---|---|
LU84746A1 (en) | 1983-11-17 |
IT1201087B (en) | 1989-01-27 |
SE463239B (en) | 1990-10-29 |
MX9203428A (en) | 1992-07-01 |
GB8308791D0 (en) | 1983-05-11 |
BE896453A (en) | 1983-08-01 |
FR2525223A1 (en) | 1983-10-21 |
US4621077A (en) | 1986-11-04 |
GB2118042B (en) | 1986-01-15 |
NL980005I1 (en) | 1998-04-01 |
NL980004I1 (en) | 1998-04-01 |
IT8220781A0 (en) | 1982-04-15 |
NL970038I1 (en) | 1998-01-05 |
NL8301324A (en) | 1983-11-01 |
JPS58189193A (en) | 1983-11-04 |
LU88714I2 (en) | 1996-08-23 |
SE8302130L (en) | 1983-10-16 |
NL980010I1 (en) | 1998-05-06 |
CH661437A5 (en) | 1987-07-31 |
NL192562C (en) | 1997-10-03 |
NL192562B (en) | 1997-06-02 |
SE8302130D0 (en) | 1983-04-15 |
HK79390A (en) | 1990-10-12 |
NL970038I2 (en) | 2000-11-01 |
GB2118042A (en) | 1983-10-26 |
JPH0213645B2 (en) | 1990-04-04 |
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