FR2520379B1 - Procede de preparation d'un disaccharide-tripeptide et d'un disaccharide-tetrapeptide possedant des proprietes immunostimulantes - Google Patents

Procede de preparation d'un disaccharide-tripeptide et d'un disaccharide-tetrapeptide possedant des proprietes immunostimulantes

Info

Publication number
FR2520379B1
FR2520379B1 FR8300952A FR8300952A FR2520379B1 FR 2520379 B1 FR2520379 B1 FR 2520379B1 FR 8300952 A FR8300952 A FR 8300952A FR 8300952 A FR8300952 A FR 8300952A FR 2520379 B1 FR2520379 B1 FR 2520379B1
Authority
FR
France
Prior art keywords
disaccharide
tetrapeptide
tripeptide
preparation
immunostimulant properties
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
FR8300952A
Other languages
English (en)
Other versions
FR2520379A1 (fr
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Dainippon Pharmaceutical Co Ltd
Original Assignee
Dainippon Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dainippon Pharmaceutical Co Ltd filed Critical Dainippon Pharmaceutical Co Ltd
Publication of FR2520379A1 publication Critical patent/FR2520379A1/fr
Application granted granted Critical
Publication of FR2520379B1 publication Critical patent/FR2520379B1/fr
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20—Bacteria; Culture media therefor
    • C12N1/205—Bacterial isolates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K9/00—Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof
    • C07K9/001—Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof the peptide sequence having less than 12 amino acids and not being part of a ring structure
    • C07K9/005—Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof the peptide sequence having less than 12 amino acids and not being part of a ring structure containing within the molecule the substructure with m, n > 0 and m+n > 0, A, B, D, E being heteroatoms; X being a bond or a chain, e.g. muramylpeptides
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00—Preparation of peptides or proteins
    • C12P21/06—Preparation of peptides or proteins produced by the hydrolysis of a peptide bond, e.g. hydrolysate products
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00—Microorganisms ; Processes using microorganisms
    • C12R2001/01—Bacteria or Actinomycetales ; using bacteria or Actinomycetales
    • C12R2001/465—Streptomyces
FR8300952A 1982-01-22 1983-01-21 Procede de preparation d'un disaccharide-tripeptide et d'un disaccharide-tetrapeptide possedant des proprietes immunostimulantes Expired FR2520379B1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP57009237A JPS58126797A (ja) 1982-01-22 1982-01-22 ジサツカライドトリペプチド及びジサツカライドテトラペプチドの製法

Publications (2)

Publication Number Publication Date
FR2520379A1 FR2520379A1 (fr) 1983-07-29
FR2520379B1 true FR2520379B1 (fr) 1985-11-22

Family

ID=11714787

Family Applications (1)

Application Number Title Priority Date Filing Date
FR8300952A Expired FR2520379B1 (fr) 1982-01-22 1983-01-21 Procede de preparation d'un disaccharide-tripeptide et d'un disaccharide-tetrapeptide possedant des proprietes immunostimulantes

Country Status (4)

Country Link
US (1) US4515891A (fr)
JP (1) JPS58126797A (fr)
DE (1) DE3301997A1 (fr)
FR (1) FR2520379B1 (fr)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4950645A (en) * 1988-07-08 1990-08-21 Immunotherapeutics, Inc. Composition for macrophage activation
US5416070A (en) * 1988-07-08 1995-05-16 Immunotherapeutics, Inc. Composition for macrophage activation
JP2928335B2 (ja) * 1989-06-26 1999-08-03 株式会社ヤクルト本社 抗高血圧剤および飲食品
JPH04502260A (ja) * 1989-10-16 1992-04-23 アムジエン・インコーポレーテツド Ｎ―アセチルムラミダーゼ　ｍ１
CH680192A5 (fr) * 1989-12-13 1992-07-15 Nestle Sa
JP3516318B2 (ja) 1995-03-07 2004-04-05 雪印乳業株式会社 新規エンドペプチダーゼ
JP2000210050A (ja) * 1998-11-20 2000-08-02 Asama Kasei Kk 免疫調節活性分解物およびその製造方法並びにそれを用いた食品
US6827940B1 (en) 2000-05-25 2004-12-07 Aidan Products, Llc Immune-stimulating bacterial cell wall extracts
JP4300289B2 (ja) * 2002-08-27 2009-07-22 国立大学法人 岡山大学 加水分解又は脱水縮合酵素、及び当該酵素の生産方法、並びに当該酵素を用いたアミドの合成方法
US7112564B2 (en) * 2003-04-09 2006-09-26 Zylacta Corporation Biodegradable glucosaminemuramyl peptides for apoptosis modulation
EP2540818A1 (fr) * 2008-09-04 2013-01-02 OM Pharma Extraits immunomodulateurs de bactéries lactobacillus et leurs procédés de fabrication et d'utilisation
US20100055082A1 (en) * 2008-09-04 2010-03-04 Jacques Alain Bauer Immunomodulatory extracts from lactobacillus bacteria and methods of manufacturing and use thereof
CN117535211B (zh) * 2024-01-09 2024-04-16 中国医学科学院医学生物学研究所 一种白喉杆菌的培养基组合及白喉类毒素的制备方法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3929579A (en) * 1969-06-07 1975-12-30 Dainippon Pharmaceutical Co Dental caries-inducing microorganism cells lytic enzyme
US4186194A (en) * 1973-10-23 1980-01-29 Agence Nationale De Valorisation De La Recherche (Anvar) Water soluble agents effective as immunological adjuvants for stimulating, in the host the immune response to various antigens and compositions, notably vaccines containing said water soluble agents
JPS58198496A (ja) * 1982-05-14 1983-11-18 Dainippon Pharmaceut Co Ltd グルコサミニルムラミルペプチド誘導体

Also Published As

Publication number Publication date
US4515891A (en) 1985-05-07
DE3301997A1 (de) 1983-08-04
JPS58126797A (ja) 1983-07-28
FR2520379A1 (fr) 1983-07-29
JPH0147153B2 (fr) 1989-10-12

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Legal Events

Date Code Title Description
ST Notification of lapse