FR2550788B1 - Nouveau procede de preparation d'a-6-desoxytetracyclines - Google Patents

Nouveau procede de preparation d'a-6-desoxytetracyclines

Info

Publication number
FR2550788B1
FR2550788B1 FR8412815A FR8412815A FR2550788B1 FR 2550788 B1 FR2550788 B1 FR 2550788B1 FR 8412815 A FR8412815 A FR 8412815A FR 8412815 A FR8412815 A FR 8412815A FR 2550788 B1 FR2550788 B1 FR 2550788B1
Authority
FR
France
Prior art keywords
desoxytetracyclines
preparation
new process
new
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
FR8412815A
Other languages
English (en)
Other versions
FR2550788A1 (fr
Inventor
Philip Ronald Page
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Hovione Inter AG
Original Assignee
Hovione Inter AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from PT77210A external-priority patent/PT77210A/fr
Priority claimed from PT7833484A external-priority patent/PT78334A/pt
Application filed by Hovione Inter AG filed Critical Hovione Inter AG
Publication of FR2550788A1 publication Critical patent/FR2550788A1/fr
Application granted granted Critical
Publication of FR2550788B1 publication Critical patent/FR2550788B1/fr
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C231/00—Preparation of carboxylic acid amides
    • C07C231/12—Preparation of carboxylic acid amides by reactions not involving the formation of carboxamide groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C233/00—Carboxylic acid amides
FR8412815A 1983-08-17 1984-08-14 Nouveau procede de preparation d'a-6-desoxytetracyclines Expired FR2550788B1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
PT77210A PT77210A (fr) 1983-08-17 1983-08-17 Nouveau procede pour preparation de alpha-6-deoxy-tetracyclines
PT7833484A PT78334A (en) 1984-03-29 1984-03-29 Preparation of the alpha-6-deoxy-tetracyclines new process

Publications (2)

Publication Number Publication Date
FR2550788A1 FR2550788A1 (fr) 1985-02-22
FR2550788B1 true FR2550788B1 (fr) 1989-11-17

Family

ID=26653438

Family Applications (1)

Application Number Title Priority Date Filing Date
FR8412815A Expired FR2550788B1 (fr) 1983-08-17 1984-08-14 Nouveau procede de preparation d'a-6-desoxytetracyclines

Country Status (11)

Country Link
US (1) US4597904A (fr)
EP (1) EP0137661B1 (fr)
KR (1) KR870001142B1 (fr)
AU (1) AU548771B2 (fr)
CA (1) CA1242704A (fr)
DE (1) DE3480339D1 (fr)
DK (1) DK386784A (fr)
ES (1) ES8600734A1 (fr)
FR (1) FR2550788B1 (fr)
HK (1) HK70090A (fr)
NZ (1) NZ209262A (fr)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4743699A (en) * 1982-01-19 1988-05-10 Plurichemie Anstalt Homogeneous catalytic system and a process for the preparation of same
HU198173B (en) * 1987-09-18 1989-08-28 Chinoin Gyogyszer Es Vegyeszet Process for producing doxycycline
US4902447A (en) * 1988-10-28 1990-02-20 Ranbaxy Laboratories Limited Process for the production of alpha-6-deoxytetracyclines and hydrogenation catalyst useful therein
US4987242A (en) * 1988-10-28 1991-01-22 Jagmohan Khanna Hydrogenation catalyst useful in the production of alpha-6-deoxytetracyclines
US5049683A (en) * 1989-01-04 1991-09-17 Houba, Inc. Process for the production of alpha-6-deoxytetracyclines
WO1990007492A1 (fr) * 1989-01-04 1990-07-12 Houba, Inc. Procede de production d'alpha-6-desoxytetracyclines
DE68900339D1 (de) * 1989-04-03 1991-11-21 Ranbaxy Lab Ltd Verfahren zur herstellung von alpha-6-deoxytetracyclinen.
WO2005011707A1 (fr) * 2003-07-25 2005-02-10 Warner Chilcott Company, Inc. Complexe metallique de doxycycline en forme posologique solide
CN103214409B (zh) 2004-05-21 2015-10-21 哈佛大学校长及研究员协会 四环素及其类似物的合成
CN101128206A (zh) * 2005-01-21 2008-02-20 沃纳奇尔科特公司 固体剂型形式的四环素类金属络合物
WO2007117639A2 (fr) * 2006-04-07 2007-10-18 The President And Fellows Of Harvard College Synthèse de tétracyclines et d'analogues de celles-ci
US7763735B2 (en) * 2006-10-11 2010-07-27 President And Fellows Of Harvard College Synthesis of enone intermediate
US9073829B2 (en) 2009-04-30 2015-07-07 President And Fellows Of Harvard College Synthesis of tetracyclines and intermediates thereto
KR102376437B1 (ko) * 2016-10-27 2022-03-17 바나디스 다이아그노스틱스 회전환 증폭 생성물을 처리하는 방법
CN107098825B (zh) * 2017-04-10 2019-05-31 广东中农联生物制药有限公司 一种强力霉素的高效制备方法
CN107056641B (zh) * 2017-04-10 2019-05-17 河南师范大学 一种强力霉素的制备方法
CN113248397B (zh) * 2021-07-01 2021-11-05 山东国邦药业有限公司 一种盐酸多西环素的制备方法

Family Cites Families (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA668581A (en) * 1963-08-13 R. D. Mccormick Jerry Process for the catalytic reduction of 6-hydroxy hydronaphthacenes
FR1430859A (fr) * 1960-05-23 1966-05-25
US3484483A (en) * 1966-10-31 1969-12-16 Pfizer & Co C Process for producing alpha-6-deoxytetracyclines
US3444198A (en) * 1967-02-13 1969-05-13 Pfizer & Co C Process for producing alpha-6-deoxytetracyclines
US3397231A (en) * 1967-04-12 1968-08-13 Pfizer & Co C Refining of alpha-6-deoxy-5-oxytetracycline
US3442943A (en) * 1967-08-16 1969-05-06 American Cyanamid Co Process for preparing 6-deoxytetracyclines
AU2940371A (en) * 1970-06-12 1972-11-30 Societa Farmaceutici Italia 6-deoxy-5-oxytetracycline-5-esters
CA942743A (en) * 1970-07-03 1974-02-26 Ivan Villax Process for producing 6-methylenetetracyclines and 6-deoxytetracyclines
US4061676A (en) * 1970-07-03 1977-12-06 Ivan Villax Recovery of doxycycline and products thereof
US3795707A (en) * 1970-12-28 1974-03-05 Rachelle Labor Italia Spa Manufacture of alpha-6-deoxytetracyclines
US4207258A (en) * 1972-02-24 1980-06-10 Ankerfarm S.P.A. Process for the preparatin of α-6-deoxytetracyclines
SE435619C (sv) * 1973-02-01 1985-10-31 Pfizer Forfarande for framstellning av en 6alfa-deoxitetracyklin
US3954862A (en) * 1973-04-20 1976-05-04 Pfizer Inc. Process for producing α-6-deoxytetracyclines
HU167250B (fr) * 1973-06-08 1975-09-27
GB1459861A (en) * 1973-06-21 1976-12-31 Pfizer Process for 11a-dehalogenation of 11a-halotetracyclines
DK501574A (fr) * 1973-09-28 1975-05-26 Ankerfarm Spa
US3907890A (en) * 1974-05-28 1975-09-23 Pfizer Preparation of alpha-6-deoxy-5-hydroxytetracycline
US4001321A (en) * 1975-06-26 1977-01-04 Pfizer Inc. Preparation of α-6-deoxytetracyclines
AR208347A1 (es) * 1974-12-19 1976-12-20 Pfizer Mejora en la produccion de alfa-6-deoxitetraciclinas
US3962131A (en) * 1975-01-28 1976-06-08 Pfizer Inc. Rhodium containing catalyst and use thereof in preparation of 6-deoxy-5-oxytetracycline
GB1593927A (en) * 1978-05-15 1981-07-22 Pliva Pharm & Chem Works T-butyl derivatives of 5-hydroxy-tetracycline and a process for preparing the same
IT1198342B (it) * 1980-07-10 1988-12-21 Carbo Biochimica Srl Processo per la produzione di alfa-6-desossi-tetracicline
DE3131954C2 (de) * 1981-08-13 1984-10-31 Degussa Ag, 6000 Frankfurt Metallkomplexe von polymeren, gegebenenfalls vernetzten Organosiloxanaminen, Verfahren zu ihrer Herstellung und Verwendung
US4550096A (en) * 1982-01-19 1985-10-29 Plurichemie Anstalt Homogeneous catalytic system comprising rhodium, hydrazine and phosphine and a process for the preparation of same

Also Published As

Publication number Publication date
US4597904A (en) 1986-07-01
ES535223A0 (es) 1985-11-01
EP0137661A3 (en) 1987-08-19
DK386784D0 (da) 1984-08-10
NZ209262A (en) 1987-07-31
EP0137661A2 (fr) 1985-04-17
CA1242704A (fr) 1988-10-04
KR870001142B1 (ko) 1987-06-11
DK386784A (da) 1985-02-18
DE3480339D1 (en) 1989-12-07
AU3197984A (en) 1985-02-21
HK70090A (en) 1990-09-14
ES8600734A1 (es) 1985-11-01
KR850001897A (ko) 1985-04-10
FR2550788A1 (fr) 1985-02-22
AU548771B2 (en) 1986-01-02
EP0137661B1 (fr) 1989-11-02

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Legal Events

Date Code Title Description
ST Notification of lapse