FR2517680B1 - Derives n-(vinblastinoyl-23) d'acides amines, leur preparation et leur application therapeutique - Google Patents

Derives n-(vinblastinoyl-23) d'acides amines, leur preparation et leur application therapeutique

Info

Publication number
FR2517680B1
FR2517680B1 FR828220476A FR8220476A FR2517680B1 FR 2517680 B1 FR2517680 B1 FR 2517680B1 FR 828220476 A FR828220476 A FR 828220476A FR 8220476 A FR8220476 A FR 8220476A FR 2517680 B1 FR2517680 B1 FR 2517680B1
Authority
FR
France
Prior art keywords
vinblastinoyl
derivatives
preparation
amino acids
therapeutic application
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
FR828220476A
Other languages
English (en)
French (fr)
Other versions
FR2517680A1 (fr
Inventor
Andre Benoit Leon Trouet
Jean
Alfred A J Hannart
Kandukuri Sivaprasada Bhus Rao
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Ajinomoto Omnichem NV SA
Original Assignee
Omnichem SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Omnichem SA filed Critical Omnichem SA
Publication of FR2517680A1 publication Critical patent/FR2517680A1/fr
Application granted granted Critical
Publication of FR2517680B1 publication Critical patent/FR2517680B1/fr
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D519/00—Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00
    • C07D519/04—Dimeric indole alkaloids, e.g. vincaleucoblastine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
FR828220476A 1981-12-08 1982-12-07 Derives n-(vinblastinoyl-23) d'acides amines, leur preparation et leur application therapeutique Expired - Lifetime FR2517680B1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
LU83822A LU83822A1 (fr) 1981-12-08 1981-12-08 Derives n-(vinblastinoyl-23)d'acides amines,leur preparation et leur application therapeutique

Publications (2)

Publication Number Publication Date
FR2517680A1 FR2517680A1 (fr) 1983-06-10
FR2517680B1 true FR2517680B1 (fr) 1990-05-25

Family

ID=19729780

Family Applications (1)

Application Number Title Priority Date Filing Date
FR828220476A Expired - Lifetime FR2517680B1 (fr) 1981-12-08 1982-12-07 Derives n-(vinblastinoyl-23) d'acides amines, leur preparation et leur application therapeutique

Country Status (24)

Country Link
JP (1) JPS58116491A (pt)
AT (1) AT390958B (pt)
AU (1) AU564951B2 (pt)
BE (1) BE895262A (pt)
CA (1) CA1198422A (pt)
CH (1) CH655727A5 (pt)
DD (1) DD205906A5 (pt)
DE (1) DE3245269A1 (pt)
DK (1) DK161833C (pt)
ES (1) ES8401768A1 (pt)
FR (1) FR2517680B1 (pt)
GB (1) GB2111055B (pt)
GR (1) GR77280B (pt)
HU (1) HU187803B (pt)
IE (1) IE55283B1 (pt)
IL (1) IL67366A (pt)
IT (1) IT1157126B (pt)
LU (1) LU83822A1 (pt)
NL (1) NL8204711A (pt)
NZ (1) NZ202708A (pt)
OA (1) OA07270A (pt)
PT (1) PT75949B (pt)
SE (1) SE452622B (pt)
ZA (1) ZA828823B (pt)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3484691D1 (de) * 1983-04-29 1991-07-18 Omnichem Sa Konjugierte vinblastin-verbindungen und ihre derivate, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische zusammensetzungen.
US4667030A (en) * 1985-06-17 1987-05-19 Eli Lilly And Company Hydrazide succinimide derivatives of antineoplastic indole-dihydroindole alkaloids
US4675400A (en) * 1985-06-17 1987-06-23 Eli Lilly And Company Bifunctional derivatives of 4-desacetyl indole-dihydroindole alkaloids
CA1335686C (fr) * 1986-01-13 1995-05-23 Rao K. S. P. Bhushana Vinblastine et composition pharmaceutique les contenant
US4906086A (en) * 1987-06-19 1990-03-06 Honda Giken Kogyo Kabushiki Kaisha Rearview mirror device for motorcycles
FR2626882B1 (fr) * 1988-02-08 1991-11-08 Ire Celltarg Sa Conjugues de derives de vinca comportant une chaine detergente en position c-3
WO2014169697A1 (zh) * 2013-04-19 2014-10-23 暨南大学 长春碱类衍生物及其制备方法和应用

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AR204004A1 (es) 1973-04-02 1975-11-12 Lilly Co Eli Procedimientos para preparar derivados de vinblastina leurosidina y leurocristina
US3848234A (en) * 1973-04-04 1974-11-12 Sperry Rand Corp Multi-processor system with multiple cache memories
IL48685A (en) * 1975-01-09 1980-03-31 Lilly Co Eli Amides of vincadioline and vinblastine
OA06421A (fr) * 1980-06-10 1981-09-30 Omnium Chimique Sa Procédé de préparation de dérivés N-(vinblastinoyl-23) d'acides aminés et de peptides.

Also Published As

Publication number Publication date
IE55283B1 (en) 1990-08-01
IL67366A0 (en) 1983-03-31
DK161833C (da) 1992-01-20
ES517942A0 (es) 1984-01-01
ZA828823B (en) 1983-09-28
ES8401768A1 (es) 1984-01-01
AU564951B2 (en) 1987-09-03
DK161833B (da) 1991-08-19
NL8204711A (nl) 1983-07-01
JPS58116491A (ja) 1983-07-11
PT75949B (fr) 1985-10-04
GR77280B (pt) 1984-09-11
BE895262A (fr) 1983-06-07
GB2111055A (en) 1983-06-29
GB2111055B (en) 1985-07-10
FR2517680A1 (fr) 1983-06-10
NZ202708A (en) 1986-01-24
LU83822A1 (fr) 1983-09-01
AU9084782A (en) 1983-06-16
DE3245269A1 (de) 1983-07-21
CA1198422A (en) 1985-12-24
DK541882A (da) 1983-06-09
JPH0449557B2 (pt) 1992-08-11
IL67366A (en) 1987-01-30
PT75949A (fr) 1983-01-01
OA07270A (fr) 1984-04-30
IT1157126B (it) 1987-02-11
HU187803B (en) 1986-02-28
DD205906A5 (de) 1984-01-11
SE8206981D0 (sv) 1982-12-07
IE822906L (en) 1983-06-08
CH655727A5 (fr) 1986-05-15
AT390958B (de) 1990-07-25
ATA444982A (de) 1990-01-15
SE8206981L (sv) 1983-06-09
SE452622B (sv) 1987-12-07
IT8268431A0 (it) 1982-12-07

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