FR2514782A1 - Procede de preparation d'une solution aqueuse, pratiquement depourvue de cellules, d'aspartase et son application a la fabrication de l'acide aspartique - Google Patents

Procede de preparation d'une solution aqueuse, pratiquement depourvue de cellules, d'aspartase et son application a la fabrication de l'acide aspartique Download PDF

Info

Publication number
FR2514782A1
FR2514782A1 FR8212369A FR8212369A FR2514782A1 FR 2514782 A1 FR2514782 A1 FR 2514782A1 FR 8212369 A FR8212369 A FR 8212369A FR 8212369 A FR8212369 A FR 8212369A FR 2514782 A1 FR2514782 A1 FR 2514782A1
Authority
FR
France
Prior art keywords
aspartase
cells
solution
process according
aspartic acid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
FR8212369A
Other languages
English (en)
French (fr)
Inventor
David Charles Sternberg
Lois Jean Moser
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Genex Corp
Original Assignee
Genex Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Genex Corp filed Critical Genex Corp
Publication of FR2514782A1 publication Critical patent/FR2514782A1/fr
Pending legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M47/00—Means for after-treatment of the produced biomass or of the fermentation or metabolic products, e.g. storage of biomass
    • C12M47/12—Purification
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M21/00—Bioreactors or fermenters specially adapted for specific uses
    • C12M21/14—Bioreactors or fermenters specially adapted for specific uses for producing enzymes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M23/00—Constructional details, e.g. recesses, hinges
    • C12M23/34—Internal compartments or partitions
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M29/00—Means for introduction, extraction or recirculation of materials, e.g. pumps
    • C12M29/16—Hollow fibers
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/88—Lyases (4.)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/96—Stabilising an enzyme by forming an adduct or a composition; Forming enzyme conjugates
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00—Preparation of nitrogen-containing organic compounds
    • C12P13/04—Alpha- or beta- amino acids
    • C12P13/20—Aspartic acid; Asparagine

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Sustainable Development (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Clinical Laboratory Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
  • Enzymes And Modification Thereof (AREA)
FR8212369A 1981-10-15 1982-07-15 Procede de preparation d'une solution aqueuse, pratiquement depourvue de cellules, d'aspartase et son application a la fabrication de l'acide aspartique Pending FR2514782A1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US31161881A 1981-10-15 1981-10-15

Publications (1)

Publication Number Publication Date
FR2514782A1 true FR2514782A1 (fr) 1983-04-22

Family

ID=23207701

Family Applications (1)

Application Number Title Priority Date Filing Date
FR8212369A Pending FR2514782A1 (fr) 1981-10-15 1982-07-15 Procede de preparation d'une solution aqueuse, pratiquement depourvue de cellules, d'aspartase et son application a la fabrication de l'acide aspartique

Country Status (19)

Country Link
JP (1) JPS5867184A (de)
AU (1) AU8592482A (de)
BE (1) BE893838A (de)
BR (1) BR8204099A (de)
DD (1) DD207219A5 (de)
DE (1) DE3226532A1 (de)
DK (1) DK307582A (de)
ES (1) ES514018A0 (de)
FI (1) FI823502L (de)
FR (1) FR2514782A1 (de)
GB (1) GB2108128A (de)
GR (1) GR78398B (de)
IL (1) IL66262A0 (de)
IT (1) IT8267896A0 (de)
LU (1) LU84273A1 (de)
NL (1) NL8202854A (de)
PL (1) PL238624A1 (de)
SE (1) SE8204306L (de)
ZA (1) ZA824805B (de)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0102207A3 (de) * 1982-08-13 1986-03-26 The Board Of Trustees Of The Leland Stanford Junior University Verfahren zur Enzymimmobilisierung
JPS59113895A (ja) * 1982-12-03 1984-06-30 Tanabe Seiyaku Co Ltd Ｌ−アスパラギン酸の製法
FR2695638B1 (fr) * 1992-09-15 1995-04-07 Rhone Poulenc Chimie Procédé de préparation de l'acide L-aspartique via l'aspartate d'ammonium.
EP0798377B1 (de) * 1996-03-29 2001-05-23 Kyowa Hakko Kogyo Co., Ltd. Verfahren zur Herstellung von Aspartase und L-Asparginsäure

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2158330A1 (de) * 1971-10-28 1973-06-15 Tanabe Seiyaku Co
FR2197979A1 (en) * 1972-09-07 1974-03-29 Orsan Amino-transferase producing strain pseudomonas PO 7111 - for prodn of aspartic acid from fumaric acid
FR2292040A1 (fr) * 1974-11-21 1976-06-18 Liquichimica Spa Procede de production d'acide l-aspartique par fermentation d'hydrocarbure
EP0032987A1 (de) * 1979-11-27 1981-08-05 Kyowa Hakko Kogyo Co., Ltd Thermophilische Aspartase, Verfahren zur Herstellung, verwendete Kultur und sie verwendendes Verfahren zur Herstellung von L-Asparaginsäure

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2158330A1 (de) * 1971-10-28 1973-06-15 Tanabe Seiyaku Co
FR2197979A1 (en) * 1972-09-07 1974-03-29 Orsan Amino-transferase producing strain pseudomonas PO 7111 - for prodn of aspartic acid from fumaric acid
FR2292040A1 (fr) * 1974-11-21 1976-06-18 Liquichimica Spa Procede de production d'acide l-aspartique par fermentation d'hydrocarbure
EP0032987A1 (de) * 1979-11-27 1981-08-05 Kyowa Hakko Kogyo Co., Ltd Thermophilische Aspartase, Verfahren zur Herstellung, verwendete Kultur und sie verwendendes Verfahren zur Herstellung von L-Asparaginsäure

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
CHEMICAL ABSTRACTS, vol. 69, no. 7, 1968, page 2420, réf. no. 26069d, Columbus, Ohio, US; & JP - A - 68 08 713 (TANABE SEIYAKU CO., LTD.) 04.04.1968 *

Also Published As

Publication number Publication date
SE8204306L (sv) 1983-04-16
IL66262A0 (en) 1982-11-30
AU8592482A (en) 1983-04-21
SE8204306D0 (sv) 1982-07-13
ES8400142A1 (es) 1983-10-16
GB2108128A (en) 1983-05-11
FI823502L (fi) 1983-04-16
ZA824805B (en) 1983-04-27
DK307582A (da) 1983-04-16
NL8202854A (nl) 1983-05-02
DD207219A5 (de) 1984-02-22
BR8204099A (pt) 1983-07-05
GR78398B (de) 1984-09-27
JPS5867184A (ja) 1983-04-21
PL238624A1 (en) 1983-05-09
BE893838A (fr) 1982-11-03
DE3226532A1 (de) 1983-09-01
LU84273A1 (fr) 1983-02-07
ES514018A0 (es) 1983-10-16
FI823502A0 (fi) 1982-10-14
IT8267896A0 (it) 1982-07-14

Similar Documents

Publication Publication Date Title
JP5455244B2 (ja) 遊離細胞によるガラクトオリゴ糖の製造方法
IE58779B1 (en) Process for the microbiological production of l-carnitine
DK148750B (da) Fremgangsmaade til kontinuerlig fremstilling af isomaltulose
EP0206904B1 (de) Verfahren zur enzymatischen Herstellung von L-alpha-Aminosäuren aus alpha-Ketosäuren
FR2514782A1 (fr) Procede de preparation d'une solution aqueuse, pratiquement depourvue de cellules, d'aspartase et son application a la fabrication de l'acide aspartique
US6001255A (en) Process for the production of water-soluble salts of carboxylic and amino acids
FR2602519A1 (fr) Procede et installation de production en continu de fructose-1,6-diphosphate au moyen de levure immobilisee
CA2246538C (en) Crystalline protease and method for producing same
US20030073203A1 (en) Method for producing l-carnitine from crotonobetaine
CH666049A5 (fr) Enzyme bacteriolytique et son procede de preparation.
DK144277B (da) Femgangsmaade til fremstilling af 6-aminopenicillansyre
FR2481713A1 (de)
FI70592C (fi) Foerfarande foer framstaellning av uricase
JPS62111693A (ja) α−ケトカルボン酸からＬ−アミノ酸を発酵により製造する方法
Takagi et al. Production of S-(+)-ibuprofen from a nitrile compound by enzymatic reaction combined with ultrafiltration
EP0725847B1 (de) Verfahren zur herstellung von wasserlöslichen salzen von carbonsäuren und aminosäuren
EP0452240A1 (de) Verfahren und Anlage zur halbkontinuierlichen Vergärung, insbesondere zur Industrieherstellung einer biologischen Mischung auf Propionsäurebasis
CA1150654A (en) Process for the production of citric acid
FR2547593A1 (fr) Procede d'obtention de saccharose phosphorylase, saccharose phosphorylase obtenue par le procede et application a la synthese de l'acide glucose-1-phosphorique et de ses sels
FR2472608A1 (fr) Nouvelle glucose-6-phosphate-deshydrogenase, son procede de preparation et compositions coenzymatiques la contenant
JPS5982097A (ja) 固定化酵素法による６−アミノペニシラン酸の改良製造法
SU299542A1 (ru) Библиотека |
JPH047677B2 (de)
JPH04252189A (ja) ベンゼンジカルボン酸モノエステルまたはその誘導体の製造方法
FR2628751A1 (fr) Procede de production continue de l-(alpha)-amino acides a partir d'(alpha)-cetoacides a l'aide de cellules de bacillus