FR2477139A1 - Procede de preparation de tetrahydronaphtacenes, derives obtenus et intermediaires de preparation - Google Patents

Procede de preparation de tetrahydronaphtacenes, derives obtenus et intermediaires de preparation Download PDF

Info

Publication number
FR2477139A1
FR2477139A1 FR8100266A FR8100266A FR2477139A1 FR 2477139 A1 FR2477139 A1 FR 2477139A1 FR 8100266 A FR8100266 A FR 8100266A FR 8100266 A FR8100266 A FR 8100266A FR 2477139 A1 FR2477139 A1 FR 2477139A1
Authority
FR
France
Prior art keywords
formula
compound
tetrahydro
acid
methoxy
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR8100266A
Other languages
English (en)
French (fr)
Other versions
FR2477139B1 (cg-RX-API-DMAC10.html
Inventor
Michael John Broadhurst
Cedric Herbert Hassall
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
F Hoffmann La Roche AG
Original Assignee
F Hoffmann La Roche AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by F Hoffmann La Roche AG filed Critical F Hoffmann La Roche AG
Publication of FR2477139A1 publication Critical patent/FR2477139A1/fr
Application granted granted Critical
Publication of FR2477139B1 publication Critical patent/FR2477139B1/fr
Granted legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D317/00Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D317/08Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
    • C07D317/10Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings
    • C07D317/32Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/45Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by condensation
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/61Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
    • C07C45/67Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton
    • C07C45/673Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by change of size of the carbon skeleton
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C49/00Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
    • C07C49/527Unsaturated compounds containing keto groups bound to rings other than six-membered aromatic rings
    • C07C49/577Unsaturated compounds containing keto groups bound to rings other than six-membered aromatic rings containing ether groups, groups, groups, or groups
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C65/00Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C65/32Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups containing keto groups
    • C07C65/40Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups containing keto groups containing singly bound oxygen-containing groups
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D307/00Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/87Benzo [c] furans; Hydrogenated benzo [c] furans
    • C07D307/88Benzo [c] furans; Hydrogenated benzo [c] furans with one oxygen atom directly attached in position 1 or 3
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D317/00Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D317/08Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
    • C07D317/10Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings
    • C07D317/14Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D317/18Radicals substituted by singly bound oxygen or sulfur atoms
    • C07D317/22Radicals substituted by singly bound oxygen or sulfur atoms etherified
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D317/00Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D317/08Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
    • C07D317/10Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings
    • C07D317/14Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D317/26Radicals substituted by doubly bound oxygen or sulfur atoms or by two such atoms singly bound to the same carbon atom

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
FR8100266A 1980-01-22 1981-01-09 Procede de preparation de tetrahydronaphtacenes, derives obtenus et intermediaires de preparation Granted FR2477139A1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB8002008 1980-01-22
GB8037354A GB2071084B (en) 1980-01-22 1980-11-21 Polycylic compounds

Publications (2)

Publication Number Publication Date
FR2477139A1 true FR2477139A1 (fr) 1981-09-04
FR2477139B1 FR2477139B1 (cg-RX-API-DMAC10.html) 1984-05-18

Family

ID=26274226

Family Applications (1)

Application Number Title Priority Date Filing Date
FR8100266A Granted FR2477139A1 (fr) 1980-01-22 1981-01-09 Procede de preparation de tetrahydronaphtacenes, derives obtenus et intermediaires de preparation

Country Status (7)

Country Link
AT (1) AT370716B (cg-RX-API-DMAC10.html)
CH (1) CH644836A5 (cg-RX-API-DMAC10.html)
DE (1) DE3101665A1 (cg-RX-API-DMAC10.html)
FR (1) FR2477139A1 (cg-RX-API-DMAC10.html)
GB (1) GB2071084B (cg-RX-API-DMAC10.html)
IT (1) IT1135089B (cg-RX-API-DMAC10.html)
NL (1) NL8100300A (cg-RX-API-DMAC10.html)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9316931B2 (en) * 2013-03-07 2016-04-19 Canon Kabushiki Kaisha Electrophotographic photosensitive member, electrophotographic apparatus, process cartridge, and condensed polycyclic aromatic compound

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4077988A (en) * 1975-01-22 1978-03-07 Societa' Farmaceutici Italia, S.p.A. Optically active anthracyclinones
EP0007400A1 (en) * 1978-06-01 1980-02-06 Research Corporation Anthracene derivatives useful as intermediates in the preparation of daunomycinones
EP0013577A2 (en) * 1979-01-16 1980-07-23 F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft Process for the preparation of hexahydronaphthacene derivatives

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4077988A (en) * 1975-01-22 1978-03-07 Societa' Farmaceutici Italia, S.p.A. Optically active anthracyclinones
EP0007400A1 (en) * 1978-06-01 1980-02-06 Research Corporation Anthracene derivatives useful as intermediates in the preparation of daunomycinones
EP0013577A2 (en) * 1979-01-16 1980-07-23 F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft Process for the preparation of hexahydronaphthacene derivatives

Also Published As

Publication number Publication date
FR2477139B1 (cg-RX-API-DMAC10.html) 1984-05-18
AT370716B (de) 1983-04-25
NL8100300A (nl) 1981-08-17
DE3101665A1 (de) 1982-04-08
GB2071084A (en) 1981-09-16
GB2071084B (en) 1984-02-29
IT8119214A0 (it) 1981-01-20
CH644836A5 (de) 1984-08-31
ATA23281A (de) 1982-09-15
IT1135089B (it) 1986-08-20

Similar Documents

Publication Publication Date Title
FR2487349A1 (fr) Derives de l'hydronaphtalene, leur preparation et leur utilisation en therapeutique
FR2462437A1 (fr) Nouveaux derives de la camptothecine doues d'activite antitumorale et leur procede de preparation
CA2121571C (fr) Nouveaux acides et esters phenoxy isobutyriques substitues
FR2477139A1 (fr) Procede de preparation de tetrahydronaphtacenes, derives obtenus et intermediaires de preparation
FR2582648A1 (fr) Intermediaires carbacycline optiquement actifs et procedes de leur preparation
FR2601008A1 (fr) Procede de synthese stereospecifique de derives de l'indole
FR2472572A1 (fr) Nouveaux composes polycycliques derives de l'anthracene et du naphtacene et procede pour leur preparation
FR2463763A1 (fr) Derives de naphtacene, un procede et les intermediaires pour leur preparation
BE1009080A4 (fr) Procede de preparation de l'epibatidine.
FR2495150A1 (fr) Derives de tetrahydronaphtacene
FR2467210A1 (fr) Procede de preparation de derives de l'acide 1,1-dioxopenicillanique
BE887131A (fr) Procede de preparation de tetrahydronaphtacenes, derives obtenus et intermediaires de preparation
Mead et al. Erythro selective additions of tetra-n-butylammonium enolates of 2-oxetanones to aldehydes: application to tetrahydrofuran synthesis
CH476658A (fr) Procédé pour la préparation d'une dihydroxy-dicétone
CH327513A (fr) Procédé de préparation d'un dérivé du prégnane
CA2031241A1 (fr) Intermediaires, leurs procedes de preparation et leur utilisation pour la synthese des vitamines a et e
FR2499555A1 (fr) Procede de synthese de derives du 3-ceto-cyclopentene-5-oxy
BE884145R (fr) Composes indoliques nouveaux
FR2500441A1 (fr) Nouveaux medicaments derives de la 3-hydroxy dodecahydro benz (e) inden-7-one, produits derives de la 3-hydroxy dodecahydro benz (e) inden-7-one et leur procede de preparation
FR2549470A1 (fr) Procede de preparation d'esters d'alcoyle de l'acide cis-chrysanthemique et nouveaux intermediaires obtenus
FR2588869A1 (fr) Procede pour la fabrication d'acides alkanoiques
BE885657A (fr) Procede de preparation de derives de l'acide 1,1-dioxopenicillanique et produits ainsi obtenus
BE482075A (cg-RX-API-DMAC10.html)
CH284721A (fr) Procédé de préparation d'un acylamidodiol aromatique, nitré dans le noyau.
BE857099A (fr) Procede pour la preparation de phytol

Legal Events

Date Code Title Description
ER Errata listed in the french official journal (bopi)
ST Notification of lapse