FR2471982A1 - 5-amino- (3,4'-bipyridine)-6 (1h)-one-1'-oxyde, sa preparation et son utilisation comme agent cardiotonique - Google Patents

5-amino- (3,4'-bipyridine)-6 (1h)-one-1'-oxyde, sa preparation et son utilisation comme agent cardiotonique Download PDF

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Publication number
FR2471982A1
FR2471982A1 FR8025582A FR8025582A FR2471982A1 FR 2471982 A1 FR2471982 A1 FR 2471982A1 FR 8025582 A FR8025582 A FR 8025582A FR 8025582 A FR8025582 A FR 8025582A FR 2471982 A1 FR2471982 A1 FR 2471982A1
Authority
FR
France
Prior art keywords
oxide
bipyridine
acid
amino
preparation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
FR8025582A
Other languages
English (en)
French (fr)
Inventor
George Yohe Lesher
Chester Joseph Opalka Jr
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
STWB Inc
Original Assignee
Sterling Drug Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sterling Drug Inc filed Critical Sterling Drug Inc
Publication of FR2471982A1 publication Critical patent/FR2471982A1/fr
Withdrawn legal-status Critical Current

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/06Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom containing only hydrogen and carbon atoms in addition to the ring nitrogen atom
    • C07D213/22Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom containing only hydrogen and carbon atoms in addition to the ring nitrogen atom containing two or more pyridine rings directly linked together, e.g. bipyridyl
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/89Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members with hetero atoms directly attached to the ring nitrogen atom
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/04Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Cardiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hospice & Palliative Care (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyridine Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
FR8025582A 1979-12-03 1980-12-02 5-amino- (3,4'-bipyridine)-6 (1h)-one-1'-oxyde, sa preparation et son utilisation comme agent cardiotonique Withdrawn FR2471982A1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US9950379A 1979-12-03 1979-12-03

Publications (1)

Publication Number Publication Date
FR2471982A1 true FR2471982A1 (fr) 1981-06-26

Family

ID=22275318

Family Applications (1)

Application Number Title Priority Date Filing Date
FR8025582A Withdrawn FR2471982A1 (fr) 1979-12-03 1980-12-02 5-amino- (3,4'-bipyridine)-6 (1h)-one-1'-oxyde, sa preparation et son utilisation comme agent cardiotonique

Country Status (18)

Country Link
JP (1) JPS56103165A (xx)
KR (1) KR830004247A (xx)
AU (1) AU6472280A (xx)
BE (1) BE886437A (xx)
DE (1) DE3045637A1 (xx)
DK (1) DK513180A (xx)
ES (1) ES8200346A1 (xx)
FI (1) FI803738L (xx)
FR (1) FR2471982A1 (xx)
GB (1) GB2064533A (xx)
IL (1) IL61537A0 (xx)
IT (1) IT8026375A0 (xx)
LU (1) LU82975A1 (xx)
NL (1) NL8006511A (xx)
NO (1) NO803595L (xx)
PT (1) PT72122B (xx)
SE (1) SE8008456L (xx)
ZA (1) ZA807431B (xx)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DD298781A5 (de) * 1990-03-09 1992-03-12 Inst Wirkstofforschung Verfahren zur herstellung von 5,4'-bipyridin-1'-oxiden
EP1831168B1 (en) 2004-12-16 2014-07-02 Vertex Pharmaceuticals Inc. Pyrid-2-ones useful as inhibitors of tec family protein kinases for the treatment of inflammatory, proliferative and immunologically-mediated diseases.

Also Published As

Publication number Publication date
PT72122B (en) 1981-09-29
DE3045637A1 (de) 1981-08-27
AU6472280A (en) 1981-06-11
DK513180A (da) 1981-06-04
GB2064533A (en) 1981-06-17
NL8006511A (nl) 1981-07-01
IT8026375A0 (it) 1980-12-02
ES497345A0 (es) 1981-10-16
SE8008456L (sv) 1981-06-04
ES8200346A1 (es) 1981-10-16
NO803595L (no) 1981-06-04
KR830004247A (ko) 1983-07-09
BE886437A (fr) 1981-06-02
JPS56103165A (en) 1981-08-18
ZA807431B (en) 1981-11-25
LU82975A1 (fr) 1981-07-23
PT72122A (en) 1980-12-01
IL61537A0 (en) 1980-12-31
FI803738L (fi) 1981-06-04

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