FR2457292A1 - Purification de riboflavine - Google Patents

Purification de riboflavine

Info

Publication number
FR2457292A1
FR2457292A1 FR7912997A FR7912997A FR2457292A1 FR 2457292 A1 FR2457292 A1 FR 2457292A1 FR 7912997 A FR7912997 A FR 7912997A FR 7912997 A FR7912997 A FR 7912997A FR 2457292 A1 FR2457292 A1 FR 2457292A1
Authority
FR
France
Prior art keywords
riboflavin
sludge
broth
centrifuging
resuspended
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7912997A
Other languages
English (en)
Other versions
FR2457292B1 (fr
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merck and Co Inc
Original Assignee
Merck and Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck and Co Inc filed Critical Merck and Co Inc
Publication of FR2457292A1 publication Critical patent/FR2457292A1/fr
Application granted granted Critical
Publication of FR2457292B1 publication Critical patent/FR2457292B1/fr
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D475/00—Heterocyclic compounds containing pteridine ring systems
    • C07D475/12—Heterocyclic compounds containing pteridine ring systems containing pteridine ring systems condensed with carbocyclic rings or ring systems
    • C07D475/14—Benz [g] pteridines, e.g. riboflavin
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23K—FODDER
    • A23K20/00—Accessory food factors for animal feeding-stuffs
    • A23K20/10—Organic substances
    • A23K20/174—Vitamins
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P25/00—Preparation of compounds containing alloxazine or isoalloxazine nucleus, e.g. riboflavin

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Polymers & Plastics (AREA)
  • Wood Science & Technology (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Genetics & Genomics (AREA)
  • Animal Husbandry (AREA)
  • Biotechnology (AREA)
  • Food Science & Technology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

L'INVENTION CONCERNE LA PREPARATION DE LA RIBOFLAVINE. ON RECUEILLE LA RIBOFLAVINE A PARTIR D'UN BOUILLON DE FERMENTATION EN DILUANT LE BOUILLON AVEC UNE QUANTITE PREDETERMINEE D'EAU, EN CENTRIFUGEANT LE BOUILLON DILUE DE MANIERE A FORMER UNE BOUE, EN REMETTANT LA BOUE EN SUSPENSION AVEC UNE QUANTITE PREDETERMINEE D'EAU ET EN CENTRIFUGEANT LA BOUE REMISE EN SUSPENSION POUR OBTENIR UN PRODUIT UTILISABLE DIRECTEMENT COMME SUPPLEMENT POUR LA NOURRITURE D'ANIMAUX OU SUSCEPTIBLE DE PURIFICATION SUPPLEMENTAIRE POUR UTILISATION PHARMACEUTIQUE. EVENTUELLEMENT, ON TRAITE LE BOUILLON OU LA BOUE REMISE EN SUSPENSION AVEC UNE ENZYME AVANT LA CENTRIFUGATION. CE PROCEDE PERMET D'OBTENIR UNE RIBOFLAVINE PLUS PURE.
FR7912997A 1975-08-29 1979-05-22 Purification de riboflavine Granted FR2457292A1 (fr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US60913275A 1975-08-29 1975-08-29
US66913976A 1976-03-22 1976-03-22
US05/850,991 US4165250A (en) 1975-08-29 1977-11-14 Riboflavin purification

Publications (2)

Publication Number Publication Date
FR2457292A1 true FR2457292A1 (fr) 1980-12-19
FR2457292B1 FR2457292B1 (fr) 1984-12-07

Family

ID=27417012

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7912997A Granted FR2457292A1 (fr) 1975-08-29 1979-05-22 Purification de riboflavine

Country Status (8)

Country Link
US (1) US4165250A (fr)
BE (1) BE876426A (fr)
CH (1) CH643261A5 (fr)
DE (1) DE2920592A1 (fr)
FR (1) FR2457292A1 (fr)
GB (1) GB2048889B (fr)
NL (1) NL7904180A (fr)
SE (1) SE432444B (fr)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0137226B1 (fr) * 1983-09-09 1990-11-14 Daicel Chemical Industries, Ltd. Procédé de préparation de riboflavine
DE3819745A1 (de) * 1988-06-10 1989-12-14 Basf Ag Verfahren zur herstellung von auf mikrobiellem wege hergestelltem riboflavin in form von sprueh- oder mikrogranulaten
DE4002066A1 (de) * 1990-01-25 1991-08-01 Basf Ag Verfahren zur abtrennung von riboflavin aus fermentationssuspensionen
DE4021274A1 (de) * 1990-07-04 1992-01-09 Basf Ag Verfahren zur reinigung von fermentativ hergestelltem riboflavin
DE4037441A1 (de) * 1990-11-24 1992-05-27 Basf Ag Verfahren zur erhoehung des riboflavin-gahaltes in spruehgetrockneten fermenteraustraegen bei riboflavin-fermentationen
JP2979767B2 (ja) * 1991-09-09 1999-11-15 味の素株式会社 発酵法によるリボフラビンの製造法
KR20060063908A (ko) * 2003-07-22 2006-06-12 디에스엠 아이피 어셋츠 비.브이. 리보플라빈의 정제방법
EP1731617A1 (fr) * 2005-06-06 2006-12-13 DSM IP Assets B.V. Recyclage d'une biomasse lysée comme milieu nutritif dans la préparation fermentative de la riboflavine.
US10301588B2 (en) 2014-12-10 2019-05-28 Basf Se Method of removing DNA from biotechnological products
CN106957129B (zh) * 2017-03-30 2020-01-03 湖北广济药业股份有限公司 一种核黄素发酵液的处理方法
CN108308431B (zh) * 2018-05-08 2022-11-04 焦作市佰役安生物工程有限公司 一种含有核黄素发酵废液的猪用饲料添加剂及其制备方法

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2822361A (en) * 1954-06-22 1958-02-04 Grain Processing Corp Riboflavin recovery

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2483855A (en) * 1942-03-16 1949-10-04 Commercial Solvents Corp Biochemical process for the production of riboflavin
US2387023A (en) * 1944-06-10 1945-10-16 Commercial Solvents Corp Process for the recovery of riboflavin
GB621469A (en) * 1944-12-19 1949-04-11 Commercial Solvents Corp Improvements in or relating to process for recovering riboflavin
US2571896A (en) * 1945-10-31 1951-10-16 Merck & Co Inc Recovery of riboflavin
NL68936C (fr) * 1946-01-11
US2797215A (en) * 1955-04-28 1957-06-25 Commercial Solvents Corp Production of type a riboflavin crystals
US2807611A (en) * 1955-10-13 1957-09-24 Merck & Co Inc Process for producing riboflavin
US3576719A (en) * 1968-04-23 1971-04-27 Squibb & Sons Inc Alkaline proteinase

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2822361A (en) * 1954-06-22 1958-02-04 Grain Processing Corp Riboflavin recovery

Also Published As

Publication number Publication date
FR2457292B1 (fr) 1984-12-07
US4165250A (en) 1979-08-21
NL7904180A (nl) 1980-12-02
SE7904349L (sv) 1980-11-18
CH643261A5 (de) 1984-05-30
GB2048889A (en) 1980-12-17
DE2920592C2 (fr) 1987-10-22
BE876426A (fr) 1979-11-21
DE2920592A1 (de) 1980-12-04
SE432444B (sv) 1984-04-02
GB2048889B (en) 1983-05-18

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