SU572201A3 - Способ получени метилового эфира 5-пропилтио-2-бензимидазолкарбаминовой кислоты - Google Patents

Способ получени метилового эфира 5-пропилтио-2-бензимидазолкарбаминовой кислоты

Info

Publication number
SU572201A3
SU572201A3 SU7502145903A SU2145903A SU572201A3 SU 572201 A3 SU572201 A3 SU 572201A3 SU 7502145903 A SU7502145903 A SU 7502145903A SU 2145903 A SU2145903 A SU 2145903A SU 572201 A3 SU572201 A3 SU 572201A3
Authority
SU
USSR - Soviet Union
Prior art keywords
acid
propyltio
benzimidazolcarbamic
methyl ester
preparing methyl
Prior art date
Application number
SU7502145903A
Other languages
English (en)
Inventor
Джон Гьюрик Роберт
Джон Теодорайдз Вассилиос
Original Assignee
Смитклайн Корпорейшн (Фирма)
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=23908789&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=SU572201(A3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Смитклайн Корпорейшн (Фирма) filed Critical Смитклайн Корпорейшн (Фирма)
Application granted granted Critical
Publication of SU572201A3 publication Critical patent/SU572201A3/ru

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D235/00Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
    • C07D235/02Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
    • C07D235/04Benzimidazoles; Hydrogenated benzimidazoles
    • C07D235/24Benzimidazoles; Hydrogenated benzimidazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
    • C07D235/30Nitrogen atoms not forming part of a nitro radical
    • C07D235/32Benzimidazole-2-carbamic acids, unsubstituted or substituted; Esters thereof; Thio-analogues thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00Antiparasitic agents

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Fodder In General (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Description

(54) СПОСОБ ПОЛУЧЕНИЯ МЕТИЛОВОГО ЭФИРА 5-ПРОПИЛТИО - БЕНЗИМИДАЗОЛКАРБАМИНОВОЙ КИСЛОТЫ 3 т л и ч a ю щ и и с   тем, что цианамид подаергают взаимодействию с метш1хлорформиатом, образовавшийс  карбометоксицианамид обрабатывают 4-п опилтио-о-фенилендиамином или его солью   ььдел юг целевой продакт в свободном виде. 2. Способ по и. 1, о т л и ч а ю щ и и с   тем, что 4 процесс провод т в среде смешивающегос  «с водои растворител , например в водном ацетоне, или в воде. . Источники информации, прин тые во внимание jj лри экспертизе: 1. Патент США № 3574845, кл. 424-273, 13.04.71.
SU7502145903A 1974-06-19 1975-06-18 Способ получени метилового эфира 5-пропилтио-2-бензимидазолкарбаминовой кислоты SU572201A3 (ru)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US480646A US3915986A (en) 1974-06-19 1974-06-19 Methyl 5-propylthio-2-benzimidazolecarbamate

Publications (1)

Publication Number Publication Date
SU572201A3 true SU572201A3 (ru) 1977-09-05

Family

ID=23908789

Family Applications (1)

Application Number Title Priority Date Filing Date
SU7502145903A SU572201A3 (ru) 1974-06-19 1975-06-18 Способ получени метилового эфира 5-пропилтио-2-бензимидазолкарбаминовой кислоты

Country Status (33)

Country Link
US (2) US3915986A (ru)
JP (2) JPS609488B2 (ru)
AR (1) AR207248A1 (ru)
BE (1) BE830203A (ru)
CA (1) CA1052798A (ru)
CH (1) CH616157A5 (ru)
CY (1) CY1039A (ru)
DD (1) DD118089A5 (ru)
DE (1) DE2527065C3 (ru)
DK (1) DK135716B (ru)
ES (1) ES438452A1 (ru)
FI (1) FI59247C (ru)
FR (1) FR2275203A1 (ru)
GB (1) GB1464326A (ru)
GT (1) GT198062984A (ru)
HK (1) HK6880A (ru)
HU (1) HU172538B (ru)
IE (1) IE41379B1 (ru)
IL (1) IL47465A (ru)
IT (1) IT1038925B (ru)
KE (1) KE3014A (ru)
LU (1) LU72740A1 (ru)
MX (1) MX3978E (ru)
MY (1) MY8000260A (ru)
NL (1) NL170144C (ru)
NO (1) NO142813C (ru)
OA (1) OA05107A (ru)
PH (1) PH14561A (ru)
PL (1) PL99359B1 (ru)
SE (1) SE420313B (ru)
SU (1) SU572201A3 (ru)
YU (1) YU39322B (ru)
ZA (1) ZA753236B (ru)

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1076022B (it) * 1977-04-20 1985-04-22 Montedison Spa Benzimidazolcarbammati antielmintici
SE443977B (sv) * 1977-05-10 1986-03-17 Chinoin Gyogyszer Es Vegyeszet Forfarande for framstellning av 5(6)-tio-bensimidazolderivat
IT1107749B (it) * 1977-10-06 1985-11-25 Montedison Spa Benzimidazolcarbammato particolarmente attivo contro i parassiti gastroenterici e polmonari
US4152522A (en) * 1978-01-03 1979-05-01 Ethyl Corporation Process for the preparation of 2-benzimidazole carbamates
US4136174A (en) * 1978-01-18 1979-01-23 E. R. Squibb & Sons, Inc. Benzimidazolecarbamates and method
US4156006A (en) * 1978-01-09 1979-05-22 E. R. Squibb & Sons, Inc. Vinyl sulfide derivatives of benzimidazoles
DE2840927A1 (de) * 1978-09-20 1980-04-10 Bayer Ag 3,4-dihydroisochinoline, verfahren zu ihrer herstellung sowie ihre verwendung als arzneimittel
SE445641B (sv) * 1978-12-06 1986-07-07 Montedison Spa Bensimidazolkarbamat och forfarande for framstellning derav
JPS5836122B2 (ja) * 1979-11-19 1983-08-06 名古屋高速道路公社 回転支保工による橋脚の張出し梁施工法
US4299837A (en) * 1979-12-05 1981-11-10 Montedison S.P.A. Anthelmintic benzimidazole-carbamates
EP0167491A3 (de) * 1984-07-06 1986-12-30 Ciba-Geigy Ag Thiobarbitursäurederivate
EP0430885A3 (en) * 1989-12-01 1991-11-06 Ciba-Geigy Ag Anthelmintical compounds
GB9106278D0 (en) * 1991-03-25 1991-05-08 Smithkline Beecham Plc Method of treatment
GB9115272D0 (en) * 1991-07-15 1991-08-28 Pfizer Ltd Benzimidazole anthelmintics
GB9124002D0 (en) * 1991-11-12 1992-01-02 Pfizer Ltd Benzimidazole anthelmintic agents
GB9205368D0 (en) * 1992-03-12 1992-04-22 Pfizer Ltd Benzimidozole anthelmintic agents
US5645819A (en) * 1995-03-13 1997-07-08 Klapow; Lawrence A. Methods of diagnosing and treating an intestinal and lung roundworm infection
US5861142A (en) * 1996-03-25 1999-01-19 Schick; Mary Pichler Method for promoting hair, nail, and skin keratinization
WO1997047610A1 (en) * 1996-06-07 1997-12-18 Novartis Ag Benzazole derivatives
US7893271B2 (en) * 2005-07-28 2011-02-22 Intervet International B.V. Benzimidazole carbamates and (thio) carbamates, and the synthesis and use thereof
EP2032046B1 (en) * 2006-06-12 2015-11-04 Smith & Nephew, Inc. Systems and devices for tibial resection
CA2660647C (en) 2006-06-14 2015-07-28 Intervet International B.V. A suspension comprising benzimidazole carbamate and a polysorbate
WO2016157064A1 (en) 2015-03-30 2016-10-06 Deva Holding Anonim Sirketi Stable ricobendazole formulations
MA41623A (fr) 2015-11-26 2018-01-09 Verano Ilac Sanayi Ve Ticaret A S Composition lyophilisée de composé de benzimidazole
WO2017097855A1 (en) 2015-12-08 2017-06-15 Verano Ilac Sanayi Ticaret Anonim Sirketi An injectable composition of ricobendazole
CN107935939A (zh) * 2017-11-09 2018-04-20 华中药业股份有限公司 一种阿苯达唑的精制方法
BR102020021181A2 (pt) 2020-10-16 2022-04-26 Ipanema Industria De Produtos Veterinarios Ltda Microssuspensão contra parasitas e método para sua obtenção

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE666795A (ru) * 1964-08-04 1966-01-13
US3847932A (en) * 1967-10-26 1974-11-12 Ciba Geigy Ag Benzimidazole compounds and pesticidal preparations containing them
US3840550A (en) * 1971-05-24 1974-10-08 Ciba Geigy Corp Certain 6-isothiocyanobenzothiazoles

Also Published As

Publication number Publication date
IT1038925B (it) 1979-11-30
FI751804A (ru) 1975-12-20
AR207248A1 (es) 1976-09-22
FI59247B (fi) 1981-03-31
CH616157A5 (ru) 1980-03-14
FR2275203B1 (ru) 1980-03-07
US3956499A (en) 1976-05-11
IE41379B1 (en) 1979-12-19
DK266175A (ru) 1975-12-20
YU39322B (en) 1984-10-31
DK135716B (da) 1977-06-13
ZA753236B (en) 1976-04-28
MY8000260A (en) 1980-12-31
DE2527065A1 (de) 1976-01-08
JPS60120871A (ja) 1985-06-28
CY1039A (en) 1980-08-01
DE2527065C3 (de) 1981-08-20
DK135716C (ru) 1977-11-14
BE830203A (fr) 1975-12-15
NO142813C (no) 1980-10-22
IL47465A0 (en) 1975-08-31
DD118089A5 (ru) 1976-02-12
NO142813B (no) 1980-07-14
IE41379L (en) 1975-12-19
HU172538B (hu) 1978-09-28
CA1052798A (en) 1979-04-17
NL170144C (nl) 1982-10-01
DE2527065B2 (de) 1980-10-09
NL7507190A (nl) 1975-12-23
MX3978E (es) 1981-10-20
GT198062984A (es) 1981-10-10
JPS609488B2 (ja) 1985-03-11
FI59247C (fi) 1981-07-10
NO752152L (ru) 1975-12-22
SE7506996L (sv) 1975-12-22
JPS5112936A (ru) 1976-01-31
PL99359B1 (pl) 1978-07-31
IL47465A (en) 1978-07-31
NL170144B (nl) 1982-05-03
KE3014A (en) 1980-02-15
LU72740A1 (ru) 1975-10-08
PH14561A (en) 1981-09-24
GB1464326A (en) 1977-02-09
JPS6210990B2 (ru) 1987-03-10
HK6880A (en) 1980-03-07
YU155975A (en) 1982-08-31
ES438452A1 (es) 1977-02-01
SE420313B (sv) 1981-09-28
AU8199575A (en) 1976-12-16
FR2275203A1 (fr) 1976-01-16
OA05107A (fr) 1981-01-31
US3915986A (en) 1975-10-28

Similar Documents

Publication Publication Date Title
SU572201A3 (ru) Способ получени метилового эфира 5-пропилтио-2-бензимидазолкарбаминовой кислоты
FR2324735A1 (fr) Procede de preparation de peaux depilees pretes a tanner a partir de cuirs et peaux d'animaux
BE781567A (fr) Procede de preparation en continu d'acide terephtalique de haute puret
ATE3879T1 (de) Herstellung von fructose und nuetzliche nebenprodukte.
FR2292040A1 (fr) Procede de production d'acide l-aspartique par fermentation d'hydrocarbure
BE834221A (fr) Procede de preparation d'esters d'acides n-triorganosilyl-carbamiques
JPS5218886A (en) Production of amino acids by fermentation process
BE827987A (fr) Procede catalytique continu de production de l'acide acetique
FR2292041A1 (fr) Procede pour la production d'acide l-aspartique par fermentation
BE821676A (fr) Procede de preparation d'esters tetra-alcoxyalkyliques d'acide ortho-silicique
OA04219A (fr) Nouveau procédé de préparation de l'acide (benzol-3-phényl)-2 propionique et analogues.
HU172246B (hu) Sposob poluchenija solejj khlorouksusnojj kisloty
JPS5239642A (en) A process for preparing protocatechualdehyde
SU487890A1 (ru) Способ выделени аминазина
SU497283A1 (ru) Способ получени -оксиэтиловых эфиров бензойной или оксибензойных кислот
BE828683A (fr) Procede de preparation de 0,0-diesters d'acide dithiophosphorique
SU382633A1 (ru) СПОСОБ ПОЛУЧЕНИЯ ЭФИРОВ Ы-СУЛЬФОЛАНИЛАЛ\ИНО-уксусной кислоты
SU461925A1 (ru) Способ получени 3,3,8,8-тетраметил2,7-диоксаспиро (4,4) нонан-1,6диона
BE779516A (fr) Procede de preparation d'esters d'acides alkyl-sulfoniques de composes 1,3,2-oxazaphospha-cycliques
BE814616A (fr) Procede de preparation de l'acide itaconique et de ses derives
ES432845A1 (es) Procedimiento para la purificacion de calcitoninas.
IL47437A (en) Process for the preparation of 15-hydroxy-15-alkenyl-9/oxo-prosta-(5z-13e)dienoic acid derivatives and certain products obtained by said process
BE827264A (fr) Procede de preparation d'hydroxyalcoylamides d'acides alcane-sulfoniques
GB1347539A (en) Method for the production of alicyclic ketenes and products obtained thereby
BE833709R (fr) Procede de preparation des esters de chloralkyle de l'acide chlorocarbonique