FR2455573A1 - Procede de chloruration du groupe carboxyle d'a-aminoacides et les chlorhydrates obtenus - Google Patents

Procede de chloruration du groupe carboxyle d'a-aminoacides et les chlorhydrates obtenus

Info

Publication number
FR2455573A1
FR2455573A1 FR8003374A FR8003374A FR2455573A1 FR 2455573 A1 FR2455573 A1 FR 2455573A1 FR 8003374 A FR8003374 A FR 8003374A FR 8003374 A FR8003374 A FR 8003374A FR 2455573 A1 FR2455573 A1 FR 2455573A1
Authority
FR
France
Prior art keywords
chlorination
carboxyl group
hydrochloride
chlorhydrates
amino acids
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR8003374A
Other languages
English (en)
Other versions
FR2455573B1 (fr
Inventor
Rodolfo Maggi
Gian Piero Maggi
Giuliano Marcon
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Chimica Bulciago Srl
Original Assignee
Chimica Bulciago Srl
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chimica Bulciago Srl filed Critical Chimica Bulciago Srl
Publication of FR2455573A1 publication Critical patent/FR2455573A1/fr
Application granted granted Critical
Publication of FR2455573B1 publication Critical patent/FR2455573B1/fr
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C227/00—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C227/14—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton from compounds containing already amino and carboxyl groups or derivatives thereof
    • C07C227/18—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton from compounds containing already amino and carboxyl groups or derivatives thereof by reactions involving amino or carboxyl groups, e.g. hydrolysis of esters or amides, by formation of halides, salts or esters
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C229/02—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton
    • C07C229/34—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton containing six-membered aromatic rings
    • C07C229/36—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton containing six-membered aromatic rings with at least one amino group and one carboxyl group bound to the same carbon atom of the carbon skeleton

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

L'INVENTION SE RAPPORTE A UN PROCEDE AMELIORE POUR LA CHLORURATION DU GROUPE CARBOXYLE D'A-AMINOACIDES, EN PARTICULIER DU P-HYDROXYPHENYLGLYCINE ET DU 2-PHENYLGLYCINE. LE PROCEDE COMPREND ESSENTIELLEMENT LES ETAPES DE MISE EN SUSPENSION DE L'AMINOACIDE DANS AU MOINS UN SOLVANT ORGANIQUE ET TRAITEMENT DE LA SUSPENSION OBTENUE PAR DE L'HCL GAZEUX A TEMPERATURE AMBIANTE POUR OBTENIR LE CHLORHYDRATE DE L'AMINOACIDE ET DE CHLORURATION ENTRE 10 ET 30C DU CHLORHYDRATE AVEC UN REACTIF REPONDANT A LA FORMULE GENERALE (XCL.RRNCHO) DANS LEQUEL X EST SO OU SO ET R ET R SONT DES RADICAUX ALKYLE INFERIEURS OU ARYL. APPLICATION A LA PRODUCTION DE PENICILLINES.
FR8003374A 1979-05-03 1980-02-15 Procede de chloruration du groupe carboxyle d'a-aminoacides et les chlorhydrates obtenus Expired FR2455573B1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT22323/79A IT1113934B (it) 1979-05-03 1979-05-03 Procedimento perfezionato di clorurazione del gruppo carbossilico di alfa-amminoacidi

Publications (2)

Publication Number Publication Date
FR2455573A1 true FR2455573A1 (fr) 1980-11-28
FR2455573B1 FR2455573B1 (fr) 1985-09-06

Family

ID=11194666

Family Applications (1)

Application Number Title Priority Date Filing Date
FR8003374A Expired FR2455573B1 (fr) 1979-05-03 1980-02-15 Procede de chloruration du groupe carboxyle d'a-aminoacides et les chlorhydrates obtenus

Country Status (21)

Country Link
US (2) US4369146A (fr)
JP (1) JPS55145645A (fr)
AR (1) AR224259A1 (fr)
AT (1) AT370084B (fr)
BE (1) BE881984A (fr)
CA (1) CA1133011A (fr)
CH (1) CH647498A5 (fr)
DE (1) DE3015513A1 (fr)
DK (1) DK58280A (fr)
ES (1) ES8103022A1 (fr)
FI (1) FI800692A (fr)
FR (1) FR2455573B1 (fr)
GB (1) GB2048244B (fr)
HU (1) HU182078B (fr)
IE (1) IE49641B1 (fr)
IL (1) IL59365A (fr)
IT (1) IT1113934B (fr)
NL (1) NL8000933A (fr)
PT (1) PT70895A (fr)
SE (1) SE8001037L (fr)
YU (1) YU43880A (fr)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL9300422A (nl) * 1993-03-09 1994-10-03 Westspur Investment Ltd Werkwijze voor de bereiding van D-(-)-fenylglycinechloridehydrochloride.

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2275445A1 (fr) * 1974-06-19 1976-01-16 Bristol Myers Co Procede de preparation du chlorhydrate de chlorure de d-(-)-(p-hydroxyphenyl)-2-glycyle
FR2426041A1 (fr) * 1978-05-16 1979-12-14 Chimica Bulciago Srl Procede de chloration d'a-aminoacides

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2275445A1 (fr) * 1974-06-19 1976-01-16 Bristol Myers Co Procede de preparation du chlorhydrate de chlorure de d-(-)-(p-hydroxyphenyl)-2-glycyle
FR2426041A1 (fr) * 1978-05-16 1979-12-14 Chimica Bulciago Srl Procede de chloration d'a-aminoacides

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
EXBK/59 *
EXBK/60 *
EXBK/78 *

Also Published As

Publication number Publication date
ATA87580A (de) 1982-07-15
PT70895A (en) 1980-04-01
DK58280A (da) 1980-11-04
GB2048244B (en) 1983-11-23
CH647498A5 (it) 1985-01-31
IT7922323A0 (it) 1979-05-03
IL59365A0 (en) 1980-05-30
DE3015513A1 (de) 1980-11-06
HU182078B (en) 1983-12-28
CA1133011A (fr) 1982-10-05
US4435333A (en) 1984-03-06
BE881984A (fr) 1980-06-16
GB2048244A (en) 1980-12-10
ES488797A0 (es) 1981-02-16
NL8000933A (nl) 1980-11-05
US4369146A (en) 1983-01-18
YU43880A (en) 1983-02-28
AR224259A1 (es) 1981-11-13
AT370084B (de) 1983-02-25
IE800268L (en) 1980-11-03
JPS55145645A (en) 1980-11-13
SE8001037L (sv) 1980-11-04
IT1113934B (it) 1986-01-27
FR2455573B1 (fr) 1985-09-06
ES8103022A1 (es) 1981-02-16
IE49641B1 (en) 1985-11-13
FI800692A (fi) 1980-11-04
IL59365A (en) 1984-01-31

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