FR2443457B1 - - Google Patents

Info

Publication number
FR2443457B1
FR2443457B1 FR8003187A FR8003187A FR2443457B1 FR 2443457 B1 FR2443457 B1 FR 2443457B1 FR 8003187 A FR8003187 A FR 8003187A FR 8003187 A FR8003187 A FR 8003187A FR 2443457 B1 FR2443457 B1 FR 2443457B1
Authority
FR
France
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
FR8003187A
Other versions
FR2443457A1 (fr
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Continental Pharma Inc
Original Assignee
Continental Pharma Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Continental Pharma Inc filed Critical Continental Pharma Inc
Publication of FR2443457A1 publication Critical patent/FR2443457A1/fr
Application granted granted Critical
Publication of FR2443457B1 publication Critical patent/FR2443457B1/fr
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/18—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C07D207/22—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/24—Oxygen or sulfur atoms
    • C07D207/26—2-Pyrrolidones
    • C07D207/263—2-Pyrrolidones with only hydrogen atoms or radicals containing only hydrogen and carbon atoms directly attached to other ring carbon atoms
    • C07D207/27—2-Pyrrolidones with only hydrogen atoms or radicals containing only hydrogen and carbon atoms directly attached to other ring carbon atoms with substituted hydrocarbon radicals directly attached to the ring nitrogen atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C317/00—Sulfones; Sulfoxides
    • C07C317/26—Sulfones; Sulfoxides having sulfone or sulfoxide groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton
    • C07C317/32—Sulfones; Sulfoxides having sulfone or sulfoxide groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton with sulfone or sulfoxide groups bound to carbon atoms of six-membered aromatic rings of the carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
    • C07C323/10—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and singly-bound oxygen atoms bound to the same carbon skeleton
    • C07C323/18—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and singly-bound oxygen atoms bound to the same carbon skeleton having the sulfur atom of at least one of the thio groups bound to a carbon atom of a six-membered aromatic ring of the carbon skeleton
    • C07C323/19—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and singly-bound oxygen atoms bound to the same carbon skeleton having the sulfur atom of at least one of the thio groups bound to a carbon atom of a six-membered aromatic ring of the carbon skeleton with singly-bound oxygen atoms bound to acyclic carbon atoms of the carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
    • C07C323/23—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton
    • C07C323/31—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton having the sulfur atom of at least one of the thio groups bound to a carbon atom of a six-membered aromatic ring of the carbon skeleton
    • C07C323/32—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton having the sulfur atom of at least one of the thio groups bound to a carbon atom of a six-membered aromatic ring of the carbon skeleton having at least one of the nitrogen atoms bound to an acyclic carbon atom of the carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D303/00—Compounds containing three-membered rings having one oxygen atom as the only ring hetero atom
    • C07D303/02—Compounds containing oxirane rings
    • C07D303/34—Compounds containing oxirane rings with hydrocarbon radicals, substituted by sulphur, selenium or tellurium atoms

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pyrrole Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
FR8003187A 1978-07-13 1980-02-13 Derives de 1-phenyl-2-amino-1-propanol, leur procede de preparation et leur utilisation comme medicaments Granted FR2443457A1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
LU79970A LU79970A1 (fr) 1978-07-13 1978-07-13 Procede de preparation de derives de 1-phenyl-1-propanol

Publications (2)

Publication Number Publication Date
FR2443457A1 FR2443457A1 (fr) 1980-07-04
FR2443457B1 true FR2443457B1 (fr) 1983-09-23

Family

ID=19728955

Family Applications (2)

Application Number Title Priority Date Filing Date
FR7918156A Granted FR2438649A1 (fr) 1978-07-13 1979-07-12 Derives de 1-phenyl-1-propanol, leur preparation et leurs utilisations therapeutiques notamment comme antihypertenseurs, vasodilatateurs peripheriques et antithrombiques
FR8003187A Granted FR2443457A1 (fr) 1978-07-13 1980-02-13 Derives de 1-phenyl-2-amino-1-propanol, leur procede de preparation et leur utilisation comme medicaments

Family Applications Before (1)

Application Number Title Priority Date Filing Date
FR7918156A Granted FR2438649A1 (fr) 1978-07-13 1979-07-12 Derives de 1-phenyl-1-propanol, leur preparation et leurs utilisations therapeutiques notamment comme antihypertenseurs, vasodilatateurs peripheriques et antithrombiques

Country Status (18)

Country Link
JP (1) JPS5943943B2 (fr)
AT (1) AT368491B (fr)
BE (1) BE877694A (fr)
CA (1) CA1127164A (fr)
CH (1) CH644355A5 (fr)
DE (1) DE2927789A1 (fr)
DK (1) DK293779A (fr)
ES (1) ES482432A1 (fr)
FI (1) FI792123A (fr)
FR (2) FR2438649A1 (fr)
GB (1) GB2025417B (fr)
IT (1) IT1122180B (fr)
LU (1) LU79970A1 (fr)
NL (1) NL7905507A (fr)
NO (1) NO148452C (fr)
PT (1) PT69909A (fr)
SE (1) SE446631B (fr)
ZA (1) ZA793554B (fr)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AT380872B (de) * 1980-12-24 1986-07-25 Continental Pharma Verfahren zur herstellung von 1-(4-isopropylthiophenyl)-2-n.octyl-amino-propa ol

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3128117A1 (de) * 1980-07-29 1982-03-11 Yamanouchi Pharmaceutical Co., Ltd., Tokyo Neue phenyl-aethylaminderivate, verfahren zu ihrer herstellung
EP0066919B1 (fr) * 1981-05-27 1985-03-20 MAGGIONI FARMACEUTICI S.p.A. Alcoyl-thio-4-phényl-éthanolamines, ayant une activité sur la circulation cérébrale, sur l'agrégation des plaquettes sanguines et sur la lipémie
FR2537132B1 (fr) * 1982-12-06 1987-01-09 Lafon Labor Nouveaux derives soufres de 2-amino-1-phenyl-1-ethanol, utilisation en therapeutique et procede de preparation
US4582918A (en) * 1984-09-19 1986-04-15 Schering Corporation Preparation of intermediates for (threo)-1-aryl-2-acylamido-3-fluoro-1-propanols
BE1014245A4 (fr) * 2001-04-03 2003-07-01 Malak Jean Composes chimiques derives de l'octopamine et leurs utilisations en tant qu'agonistes beta 3-adrenergiques.
WO2006043710A1 (fr) * 2004-10-19 2006-04-27 Reverse Proteomics Research Institute Co., Ltd. Protéine cible et gène cible pour le développement de médicaments et procédé de recherche par criblage
IL187245A0 (en) * 2007-11-08 2008-12-29 Hadasit Med Res Service Synthetic sphingolipid analogs

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR1366096A (fr) * 1962-05-28 1964-07-10 Castrol Ltd Copolymères pour utilisation dans les compositions d'huiles lubrifiantes et leurs produits intermédiaires
FR1480780A (fr) * 1965-05-24 1967-05-12 Shell Int Research Production de pyrrolidone

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AT380872B (de) * 1980-12-24 1986-07-25 Continental Pharma Verfahren zur herstellung von 1-(4-isopropylthiophenyl)-2-n.octyl-amino-propa ol

Also Published As

Publication number Publication date
CH644355A5 (fr) 1984-07-31
NO148452B (no) 1983-07-04
PT69909A (fr) 1979-08-01
IT1122180B (it) 1986-04-23
BE877694A (fr) 1979-11-05
JPS5533467A (en) 1980-03-08
CA1127164A (fr) 1982-07-06
IT7924357A0 (it) 1979-07-13
NL7905507A (nl) 1980-01-15
FR2438649B1 (fr) 1983-03-25
FR2438649A1 (fr) 1980-05-09
SE446631B (sv) 1986-09-29
LU79970A1 (fr) 1980-02-14
NO148452C (no) 1983-10-12
AT368491B (de) 1982-10-11
DE2927789A1 (de) 1980-01-24
ES482432A1 (es) 1980-04-01
NO792329L (no) 1980-01-15
DK293779A (da) 1980-01-14
FI792123A (fi) 1980-01-14
ATA483579A (de) 1982-02-15
ZA793554B (en) 1980-06-25
FR2443457A1 (fr) 1980-07-04
GB2025417A (en) 1980-01-23
GB2025417B (en) 1983-03-02
SE7905992L (sv) 1980-01-14
JPS5943943B2 (ja) 1984-10-25

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Legal Events

Date Code Title Description
TP Transmission of property
ST Notification of lapse