FR2437405A1 - Nouveaux alcoylbenzenes substitues basiques utiles comme medicaments - Google Patents

Nouveaux alcoylbenzenes substitues basiques utiles comme medicaments

Info

Publication number
FR2437405A1
FR2437405A1 FR7821101A FR7821101A FR2437405A1 FR 2437405 A1 FR2437405 A1 FR 2437405A1 FR 7821101 A FR7821101 A FR 7821101A FR 7821101 A FR7821101 A FR 7821101A FR 2437405 A1 FR2437405 A1 FR 2437405A1
Authority
FR
France
Prior art keywords
useful
alcoylbenzenes
medicaments
new basic
basic substituted
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
FR7821101A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Novartis AG
Original Assignee
Ciba Geigy AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to CH52977A priority Critical patent/CH636858A5/de
Priority to US05/867,644 priority patent/US4188396A/en
Priority to DE19782801195 priority patent/DE2801195A1/de
Priority to NL7800450A priority patent/NL7800450A/xx
Priority to GB1400/78A priority patent/GB1563590A/en
Priority to CA294,965A priority patent/CA1087190A/fr
Priority to FR7800917A priority patent/FR2377382A1/fr
Priority to ZA00780232A priority patent/ZA78232B/xx
Priority to BE184333A priority patent/BE862923A/fr
Priority to AT28378A priority patent/AT360989B/de
Priority to AU32458/78A priority patent/AU519005B2/en
Priority to SE7800480A priority patent/SE443139B/sv
Priority to DK20578A priority patent/DK20578A/da
Priority to ZA00784049A priority patent/ZA784049B/xx
Priority to JP53002867A priority patent/JPS6011901B2/ja
Priority to AU37991/78A priority patent/AU3799178A/en
Priority to NL7807554A priority patent/NL7807554A/xx
Priority to FR7821101A priority patent/FR2437405A1/fr
Application filed by Ciba Geigy AG filed Critical Ciba Geigy AG
Priority to BE189277A priority patent/BE868991R/fr
Priority to SE7807842A priority patent/SE7807842L/xx
Priority to DK783162A priority patent/DK316278A/da
Priority to AT750379A priority patent/AT360993B/de
Priority to AT750279A priority patent/AT360992B/de
Priority to AT750579A priority patent/AT360995B/de
Priority to AT750479A priority patent/AT360994B/de
Publication of FR2437405A1 publication Critical patent/FR2437405A1/fr
Priority to CH41181A priority patent/CH638783A5/de
Priority to CH41281A priority patent/CH629776A5/de
Priority to CH41081A priority patent/CH638184A5/de
Priority to CH40981A priority patent/CH637118A5/de
Priority to CH533381A priority patent/CH638784A5/de
Priority to CH452682A priority patent/CH640833A5/de
Priority to CH185983A priority patent/CH641162A5/de
Priority to HK327/83A priority patent/HK32783A/xx
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C255/00—Carboxylic acid nitriles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/26—Psychostimulants, e.g. nicotine, cocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
    • C07D211/10—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with radicals containing only carbon and hydrogen atoms attached to ring carbon atoms
    • C07D211/12—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with radicals containing only carbon and hydrogen atoms attached to ring carbon atoms with only hydrogen atoms attached to the ring nitrogen atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
    • C07D211/10—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with radicals containing only carbon and hydrogen atoms attached to ring carbon atoms
    • C07D211/14—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with radicals containing only carbon and hydrogen atoms attached to ring carbon atoms with hydrocarbon or substituted hydrocarbon radicals attached to the ring nitrogen atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
    • C07D211/10—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with radicals containing only carbon and hydrogen atoms attached to ring carbon atoms
    • C07D211/16—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with radicals containing only carbon and hydrogen atoms attached to ring carbon atoms with acylated ring nitrogen atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
    • C07D211/18—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
    • C07D211/18—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D211/20—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by singly bound oxygen or sulphur atoms
    • C07D211/22—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by singly bound oxygen or sulphur atoms by oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
    • C07D211/18—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D211/30—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by doubly bound oxygen or sulfur atoms or by two oxygen or sulfur atoms singly bound to the same carbon atom
    • C07D211/32—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by doubly bound oxygen or sulfur atoms or by two oxygen or sulfur atoms singly bound to the same carbon atom by oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D211/40—Oxygen atoms
    • C07D211/44—Oxygen atoms attached in position 4
    • C07D211/52—Oxygen atoms attached in position 4 having an aryl radical as the second substituent in position 4
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/68—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C07D211/70—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/68—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C07D211/72—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D211/74—Oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/68—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C07D211/72—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D211/78—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F3/00—Compounds containing elements of Groups 2 or 12 of the Periodic Table
    • C07F3/02—Magnesium compounds

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Hydrogenated Pyridines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

LA PRESENTE INVENTION CONCERNE DES COMPOSES CHIMIQUES NOUVEAUX. IL S'AGIT DE NOUVEAUX ALCOYL-INFERIEUR-BENZENES SUBSTITUES BASIQUES DE FORMULE GENERALE I: (CF DESSIN DANS BOPI) OU R REPRESENTE UN RADICAL DE FORMULE: (CF DESSIN DANS BOPI) OU R REPRESENTE UN BENZYLE NON SUBSTITUE, PH REPRESENTE UN RADICAL P-PHENYL EVENTUELLEMENT SUBSTITUE PAR UN ALCOYLE INFERIEUR, UN ALCOXY INFERIEUR, UN NITRO ETOU UN HALOGENE ET R REPRESENTE UN ALCOYLE INFERIEUR, SOUS FORME LIBRE OU SOUS FORME DE SEL. CES COMPOSES SONT UTILES COMME MEDICAMENTS.
FR7821101A 1977-01-17 1978-07-13 Nouveaux alcoylbenzenes substitues basiques utiles comme medicaments Withdrawn FR2437405A1 (fr)

Priority Applications (33)

Application Number Priority Date Filing Date Title
CH52977A CH636858A5 (de) 1977-01-17 1977-01-17 Verfahren zur herstellung neuer phenylazacycloalkane.
US05/867,644 US4188396A (en) 1977-01-17 1978-01-06 New phenylazacycloalkanes
DE19782801195 DE2801195A1 (de) 1977-01-17 1978-01-12 Neue phenylazacycloalkane
GB1400/78A GB1563590A (en) 1977-01-17 1978-01-13 Phenylazacycloalkanes
CA294,965A CA1087190A (fr) 1977-01-17 1978-01-13 4-phenylpiperidines substituees
FR7800917A FR2377382A1 (fr) 1977-01-17 1978-01-13 Nouveaux phenylazacycloalcanes utiles comme medicaments
ZA00780232A ZA78232B (en) 1977-01-17 1978-01-13 New phenylazacycloalkanes
NL7800450A NL7800450A (nl) 1977-01-17 1978-01-13 Nieuwe fenylazacycloalkanen.
BE184333A BE862923A (fr) 1977-01-17 1978-01-16 Nouveaux phenylazacycloalcanes utiles comme medicamments
AT28378A AT360989B (de) 1977-01-17 1978-01-16 Verfahren zur herstellung neuer phenylazacyclo- alkane und von deren salzen und optisch aktiven verbindungen
AU32458/78A AU519005B2 (en) 1977-01-17 1978-01-16 Phenylacycloakane derivatives
SE7800480A SE443139B (sv) 1977-01-17 1978-01-16 Forfarande for framstellning av nya 4-(fenyl)-piperidinforeningar
DK20578A DK20578A (da) 1977-01-17 1978-01-16 Fremgangsmaade til femstilling af aliphatisk substituerede 4-(phenyl)-1-aza-cyloalkaner samt anvendelse deraf
ZA00784049A ZA784049B (en) 1977-01-17 1978-01-17 New basically substituted alkylbenzenes
JP53002867A JPS6011901B2 (ja) 1977-01-17 1978-01-17 新規の脂肪族置換された４−フエニル−ピペリジン
AU37991/78A AU3799178A (en) 1977-01-17 1978-07-12 Basically substituted alkylbenzenes
FR7821101A FR2437405A1 (fr) 1977-01-17 1978-07-13 Nouveaux alcoylbenzenes substitues basiques utiles comme medicaments
NL7807554A NL7807554A (en) 1977-01-17 1978-07-13 Antidepressant 4-alkylphenyl-piperidine cpds. - prepd. by catalytic hydrogenation of corresp. alcohol
BE189277A BE868991R (fr) 1977-01-17 1978-07-14 Nouveaux phenylazacycloalcanes utiles comme medicaments
SE7807842A SE7807842L (sv) 1977-01-17 1978-07-14 Basiskt substituerade alkylbensener
DK783162A DK316278A (da) 1977-01-17 1978-07-14 Fremgangsmaade til fremstilling af aliphatisk substituerede 4-(phenyl)upiperdidinforbindelser
AT750479A AT360994B (de) 1977-01-17 1979-11-27 Verfahren zur herstellung neuer phenylazacyclo- alkane und von deren salzen und optisch aktiven verbindungen
AT750279A AT360992B (de) 1977-01-17 1979-11-27 Verfahren zur herstellung neuer phenylazacyclo- alkane und von deren salzen und optisch aktiven verbindungen
AT750579A AT360995B (de) 1977-01-17 1979-11-27 Verfahren zur herstellung neuer phenylazacyclo- alkane und von deren salzen und optisch aktiven verbindungen
AT750379A AT360993B (de) 1977-01-17 1979-11-27 Verfahren zur herstellung neuer phenylazacyclo- alkane und von deren salzen und optisch aktiven verbindungen
CH40981A CH637118A5 (de) 1977-01-17 1981-01-22 Verfahren zur herstellung neuer phenylazacycloalkane.
CH41081A CH638184A5 (de) 1977-01-17 1981-01-22 Verfahren zur herstellung neuer phenylazacycloalkane.
CH41281A CH629776A5 (de) 1977-01-17 1981-01-22 Verfahren zur herstellung neuer phenylazacycloalkane.
CH41181A CH638783A5 (de) 1977-01-17 1981-01-22 Verfahren zur herstellung neuer phenylazacycloalkane.
CH533381A CH638784A5 (de) 1977-01-17 1981-08-18 Verfahren zur herstellung neuer phenylazacycloalkane.
CH452682A CH640833A5 (de) 1977-01-17 1982-07-23 Phenylazacycloalkane.
CH185983A CH641162A5 (de) 1977-01-17 1983-04-06 Verfahren zur herstellung neuer phenylazacycloalkane.
HK327/83A HK32783A (en) 1977-01-17 1983-08-25 New phenylazacycloalkanes

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CH52977A CH636858A5 (de) 1977-01-17 1977-01-17 Verfahren zur herstellung neuer phenylazacycloalkane.
FR7821101A FR2437405A1 (fr) 1977-01-17 1978-07-13 Nouveaux alcoylbenzenes substitues basiques utiles comme medicaments

Publications (1)

Publication Number Publication Date
FR2437405A1 true FR2437405A1 (fr) 1980-04-25

Family

ID=25684858

Family Applications (2)

Application Number Title Priority Date Filing Date
FR7800917A Granted FR2377382A1 (fr) 1977-01-17 1978-01-13 Nouveaux phenylazacycloalcanes utiles comme medicaments
FR7821101A Withdrawn FR2437405A1 (fr) 1977-01-17 1978-07-13 Nouveaux alcoylbenzenes substitues basiques utiles comme medicaments

Family Applications Before (1)

Application Number Title Priority Date Filing Date
FR7800917A Granted FR2377382A1 (fr) 1977-01-17 1978-01-13 Nouveaux phenylazacycloalcanes utiles comme medicaments

Country Status (15)

Country Link
US (1) US4188396A (fr)
JP (1) JPS6011901B2 (fr)
AT (1) AT360989B (fr)
AU (1) AU519005B2 (fr)
BE (2) BE862923A (fr)
CA (1) CA1087190A (fr)
CH (8) CH636858A5 (fr)
DE (1) DE2801195A1 (fr)
DK (1) DK20578A (fr)
FR (2) FR2377382A1 (fr)
GB (1) GB1563590A (fr)
HK (1) HK32783A (fr)
NL (1) NL7800450A (fr)
SE (2) SE443139B (fr)
ZA (2) ZA78232B (fr)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FI792076A (fi) * 1978-07-05 1980-01-06 Ciba Geigy Ag Foerfarande foer framstaellning av nya fenylpiperidinderivat
US5212183A (en) * 1981-11-14 1993-05-18 Basf Aktiengesellschaft 4-(p-tert.-butylphenyl)-3-methylpiperidines substituted at the nitrogen, their quaternary salts and their use as fungicides
DE3614907A1 (de) * 1986-05-02 1987-11-05 Basf Ag N-substituierte pyrrolidon- und piperidinderivate und deren salze
DK0641320T3 (da) * 1991-04-17 2001-08-20 Upjohn Co Substituerede (S)-3-phenylpiperidinderivater, deres fremstilling og deres anvendelse som dopaminautoreceptorantagonister
JP3446468B2 (ja) * 1996-04-15 2003-09-16 旭硝子株式会社 ピペリジンカルビノール類の製造方法
ES2149687B1 (es) * 1998-04-08 2001-05-16 Medichem Sa Procedimiento de obtencion de (+-)-trans-4-(4-fluorofenil)-3-hidroximetilpiperidinas e intermedios de sintesis para las mismas.
WO2000037443A1 (fr) * 1998-12-22 2000-06-29 Pentech Pharmaceuticals, Inc. Procede de preparation d'intermediaires et de derives de arylpiperidine carbinol
US20010053862A1 (en) * 1998-12-22 2001-12-20 Bruce Ronsen Process for preparing arylpiperidine carbinol intermediates and derivatives

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR1459013A (fr) * 1964-08-05 1966-04-29 Allen & Hanburys Ltd Procédé de préparation de dérivés de la 4-phényl-pipéridine
US3284457A (en) * 1964-01-17 1966-11-08 Degussa 1-lower alkyl-4-substituted phenyl-1, 2, 3, 6-tetrahydropyridines and acid addition salts
DE2101997A1 (en) * 1971-01-16 1972-08-03 Farbenfabriken Bayer AG, 509öfLeverkusen 1-benzyl-4-subst-tetrahydropyridines - useful as intermediates for pharmaceuticals

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1060160A (en) * 1964-08-05 1967-03-01 Allen & Hanburys Ltd 4-phenylpiperidine derivatives
US3334104A (en) * 1964-12-18 1967-08-01 Sandoz Ag Certain substituted piperidyl sulfamides
DE2025518A1 (fr) * 1969-06-05 1970-12-10
CH554336A (de) 1972-08-31 1974-09-30 Ciba Geigy Ag Verfahren zur herstellung eines neuen alkohols.
US4024151A (en) * 1975-09-29 1977-05-17 E. R. Squibb & Sons, Inc. 4-Phenylpiperidinyl (and 4-phenyl-tetrahydropyridinyl) alkylamino-oxoalkanoic acids

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3284457A (en) * 1964-01-17 1966-11-08 Degussa 1-lower alkyl-4-substituted phenyl-1, 2, 3, 6-tetrahydropyridines and acid addition salts
FR1459013A (fr) * 1964-08-05 1966-04-29 Allen & Hanburys Ltd Procédé de préparation de dérivés de la 4-phényl-pipéridine
DE2101997A1 (en) * 1971-01-16 1972-08-03 Farbenfabriken Bayer AG, 509öfLeverkusen 1-benzyl-4-subst-tetrahydropyridines - useful as intermediates for pharmaceuticals

Also Published As

Publication number Publication date
CH640833A5 (de) 1984-01-31
BE862923A (fr) 1978-07-17
US4188396A (en) 1980-02-12
ZA784049B (en) 1979-07-25
FR2377382B1 (fr) 1981-11-27
CH638184A5 (de) 1983-09-15
SE443139B (sv) 1986-02-17
JPS5390268A (en) 1978-08-08
CH636858A5 (de) 1983-06-30
CH629776A5 (de) 1982-05-14
DE2801195A1 (de) 1978-07-20
SE7800480L (sv) 1978-07-18
JPS6011901B2 (ja) 1985-03-28
GB1563590A (en) 1980-03-26
BE868991R (fr) 1979-01-15
CH638783A5 (de) 1983-10-14
NL7800450A (nl) 1978-07-19
AT360989B (de) 1981-02-10
CH641162A5 (de) 1984-02-15
AU3245878A (en) 1979-07-26
CH637118A5 (de) 1983-07-15
FR2377382A1 (fr) 1978-08-11
ATA28378A (de) 1980-07-15
SE7807842L (sv) 1979-07-17
DK20578A (da) 1978-07-18
CA1087190A (fr) 1980-10-07
ZA78232B (en) 1978-12-27
AU519005B2 (en) 1981-11-05
HK32783A (en) 1983-09-02
CH638784A5 (de) 1983-10-14

Similar Documents

Publication Publication Date Title
FR2382441A1 (fr) Nouveaux n-(aminoalkyl substitue)-2-oxo-1-pyrrolidine-acetamides utiles en tant que medicaments et procedes pour leur preparation
FR2416888A1 (fr) Nouveaux derives de phenyl-piperazine utiles comme medicaments
DE2963097D1 (en) Process for the preparation of beta-lactam derivatives, the novel derivatives so obtainable and pharmaceutical compositions containing them
FR2361901A1 (fr) Derives de substitution de nucleotides et medicament contenant ces substances
FR2359144A1 (fr) Sels de l'acide clavulanique utilisable comme medicaments
FR2394546A1 (fr) Nouveaux derives de 1,2,3,4,6,7-hexahydro-11bah-benzo(a)-quinolizine, leur preparation et leur application en tant que medicaments
FR2370028A1 (fr) Hydroxylamines alkylees, leur procede de preparation et leur emploi comme medicaments
FR2437405A1 (fr) Nouveaux alcoylbenzenes substitues basiques utiles comme medicaments
FR2363608A1 (fr) Procede de preparation de colorants " bisazoiques "
FR2392999A1 (fr) Nouveaux derives de l'acide 6-((aminosulfonyl)-phenyl)-1,2-dihydro-2-oxonicotinique utile comme medicament
FR2355797A1 (fr) Procede de preparation de vinylcyclopropanes substitues utilisables dans la preparation d'insecticides
ES8104264A1 (es) Procedimiento para la preparacion de n- (trimetoxibencil)- n'-fenilpiperazinas
FR2392958A1 (fr) Nouveaux amino-acides fluores utiles comme medicament
FR2400008A1 (fr) Agents anti-hypertensifs
KR840006206A (ko) 이소퀴놀린 유도체의 제조방법
ES477785A1 (es) Procedimiento para la preparacion de nuevas 2-fenilimino- imidazolidinas sustituidas.
FR2457867A1 (fr) Nouveaux derives d'hydroxyamino-eburnane : leur procede de preparation, intermediaires utilises et utilisation comme medicament et comme intermediaire
ES8307249A1 (es) Procedimiento de preparacion de nuevos derivados del adamantano.
FR2361341A1 (fr) Procede de preparation d'esters de l'acide anthranilique
ES474367A1 (es) Procedimiento de preparacion de nuevos derivados del benzo- (d)tiazol.
FR2384771A1 (fr) Derives de quinazoline utiles comme medicament
FR2383152A1 (fr) Procede de preparation du 2-methyl-3-prenyl-4,5,6-trimethoxyphenol
FR2378518A1 (fr) Nouveaux medicaments a base de derives de tetrahydrodibenzopyranne
FR2431497A1 (fr) Nouveaux derives de l'acide clavulanique, utilisables comme medicament
FR2398736A1 (fr) Derives a-halogenomethyles d'aminoacides, leur procede de preparation et leur utilisation comme antiallergiques

Legal Events

Date Code Title Description
ST Notification of lapse