FR2434201B1 - Procede et necessaire de determination et de dosage immunologique d'une substance par creation d'un micro-environnement concentre - Google Patents

Procede et necessaire de determination et de dosage immunologique d'une substance par creation d'un micro-environnement concentre

Info

Publication number
FR2434201B1
FR2434201B1 FR7908533A FR7908533A FR2434201B1 FR 2434201 B1 FR2434201 B1 FR 2434201B1 FR 7908533 A FR7908533 A FR 7908533A FR 7908533 A FR7908533 A FR 7908533A FR 2434201 B1 FR2434201 B1 FR 2434201B1
Authority
FR
France
Prior art keywords
assay
creating
substance
environment
necessary
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
FR7908533A
Other languages
English (en)
French (fr)
Other versions
FR2434201A1 (fr
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Syva Co
Original Assignee
Syva Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Syva Co filed Critical Syva Co
Publication of FR2434201A1 publication Critical patent/FR2434201A1/fr
Application granted granted Critical
Publication of FR2434201B1 publication Critical patent/FR2434201B1/fr
Expired legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/58—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
    • G01N33/581—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances with enzyme label (including co-enzymes, co-factors, enzyme inhibitors or substrates)
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/58—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
    • G01N33/582—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances with fluorescent label
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/968—High energy substrates, e.g. fluorescent, chemiluminescent, radioactive
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00—Chemistry: analytical and immunological testing
    • Y10S436/805—Optical property

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Hematology (AREA)
  • Immunology (AREA)
  • Urology & Nephrology (AREA)
  • Cell Biology (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
FR7908533A 1978-04-05 1979-04-04 Procede et necessaire de determination et de dosage immunologique d'une substance par creation d'un micro-environnement concentre Expired FR2434201B1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US05/893,650 US4233402A (en) 1978-04-05 1978-04-05 Reagents and method employing channeling

Publications (2)

Publication Number Publication Date
FR2434201A1 FR2434201A1 (fr) 1980-03-21
FR2434201B1 true FR2434201B1 (fr) 1985-12-20

Family

ID=25401860

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7908533A Expired FR2434201B1 (fr) 1978-04-05 1979-04-04 Procede et necessaire de determination et de dosage immunologique d'une substance par creation d'un micro-environnement concentre

Country Status (6)

Country Link
US (1) US4233402A (https=)
JP (1) JPS54136896A (https=)
CA (1) CA1110541A (https=)
DE (1) DE2913550A1 (https=)
FR (1) FR2434201B1 (https=)
GB (1) GB2018986B (https=)

Families Citing this family (290)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2747794A1 (de) * 1977-10-25 1979-05-03 Bosch Gmbh Robert Anzeigeeinheit
US4318707A (en) * 1978-11-24 1982-03-09 Syva Company Macromolecular fluorescent quencher particle in specific receptor assays
US4287300A (en) * 1979-07-26 1981-09-01 Syva Company Charge effects in enzyme immunoassays
IT1123573B (it) * 1979-09-10 1986-04-30 Anic Spa Composizione adatta al controllo di tessuti e/o liquidi biiologici e metodo impiegante la stessa
US4446231A (en) * 1979-10-03 1984-05-01 Self Colin H Immunoassay using an amplified cyclic detection system
GB2059421A (en) * 1979-10-03 1981-04-23 Self C H Assay method and reagents therefor
US4391904A (en) * 1979-12-26 1983-07-05 Syva Company Test strip kits in immunoassays and compositions therein
US4486530A (en) * 1980-08-04 1984-12-04 Hybritech Incorporated Immunometric assays using monoclonal antibodies
US4366241A (en) * 1980-08-07 1982-12-28 Syva Company Concentrating zone method in heterogeneous immunoassays
JPS5737261A (en) * 1980-08-15 1982-03-01 Otsuka Pharmaceut Co Ltd Measuring method of physiological active substance
US4404278A (en) * 1980-11-24 1983-09-13 Syva Company Methods and compositions for assaying for the production of 1,4-dihydropyridyl
US4378428A (en) * 1981-03-30 1983-03-29 Baker Instruments Corporation Method for carrying out non-isotopic immunoassays, labeled analytes and kits for use in such assays
FR2503870A1 (fr) * 1981-04-10 1982-10-15 Fella Christian Procede de detection de la presence d'antigenes pneumocoque xiv dans un prelevement de cellules humaines, et produits pour mettre en oeuvre ce procede
US4442218A (en) * 1981-05-27 1984-04-10 Corning Glass Works Method of measuring degree of partitioning
JPS585659A (ja) * 1981-06-24 1983-01-13 ハイブリテツク　インコ−ポレ−テツド 単クロ−ン性抗体を使用する免疫学的、抑制試験
CA1185177A (en) * 1981-07-17 1985-04-09 Larry E. Morrison Non-radiative energy transfer immunochemical technique
US4629690A (en) * 1981-09-18 1986-12-16 Syntex (U.S.A.) Inc. Homogeneous enzyme specific binding assay on non-porous surface
CA1209889A (en) * 1981-09-18 1986-08-19 Litai Weng Homogeneous assay on a non-porous surface
US4463090A (en) * 1981-09-30 1984-07-31 Harris Curtis C Cascade amplification enzyme immunoassay
US4562148A (en) * 1981-11-06 1985-12-31 Miles Laboratories, Inc. Analytical element and method for preventing reagent migration
US5292668A (en) * 1981-12-21 1994-03-08 Boston Biomedical Research Institute, Inc. Bispecific antibody determinants
DE3380263D1 (en) * 1982-04-14 1989-08-31 Radiometer Corporate Dev Limit Microbiological test processes and apparatus
US4663278A (en) * 1982-04-30 1987-05-05 Syva Company Agglutination dependent enzyme channeling immunoassay
US4435504A (en) * 1982-07-15 1984-03-06 Syva Company Immunochromatographic assay with support having bound "MIP" and second enzyme
US5512329A (en) * 1982-09-29 1996-04-30 Bsi Corporation Substrate surface preparation
US4614712A (en) * 1983-02-25 1986-09-30 The Upjohn Company Immunoassays with luciferase labeled ligands or receptors
US4687735A (en) * 1983-03-14 1987-08-18 Syntex (U.S.A.) Inc. Enzymatic poly-reactant channeling binding assay
US4536479A (en) * 1983-03-22 1985-08-20 E. I. Du Pont De Nemours And Company Use of anti-idiotype antibodies in immunoassays
US4550075A (en) * 1983-06-22 1985-10-29 Kallestad Laboratories, Inc. Method for ligand determination utilizing an immunoassay monitorable by biotin-containing enzymes, and compositions therefor
USRE34405E (en) * 1983-08-01 1993-10-12 Abbott Laboratories Determination of analytes in particle-containing medium
JPS6071958A (ja) * 1983-09-28 1985-04-23 Akio Tsuji 酵素免疫測定法
ZA849595B (en) * 1983-12-12 1985-07-31 Miles Lab Hybridization assay employing labeled probe and anti-hybrid
EP0152254A3 (en) * 1984-02-06 1986-08-06 E.I. Du Pont De Nemours And Company Chromogenic support immunoassay utilizing labeled complement components
US4645828A (en) 1984-03-23 1987-02-24 Oncogen Platelet related growth regulator
DE3583278D1 (de) * 1984-04-23 1991-07-25 Boston Biomed Res Inst Doppelspezifische antikoerper-determinanten.
AU560779B2 (en) * 1985-01-24 1987-04-16 Quidel Assay for drugs of abuse
IE64785B1 (en) 1985-04-08 1995-09-06 Genetic Systems Corp Expression of immunologically reactive viral proteins
EP0245477A4 (en) * 1985-11-19 1989-08-09 Univ Johns Hopkins Capacitive sensor for chemical analysis and measurement.
JPH0799369B2 (ja) * 1985-11-25 1995-10-25 日本ケミカルリサーチ株式会社 上皮細胞増殖因子の酵素免疫測定法
US5190864A (en) * 1986-04-15 1993-03-02 Northeastern University Enzyme amplification by using free enzyme to release enzyme from an immobilized enzyme material
US4937188A (en) * 1986-04-15 1990-06-26 Northeastern University Enzyme activity amplification method for increasing assay sensitivity
US4777128A (en) * 1986-05-27 1988-10-11 Ethigen Corporation Fluorescence immunoassay involving energy transfer between two fluorophores
US4888276A (en) * 1986-06-26 1989-12-19 Minnesota Mining And Manufacturing Company Method and composition for the diagnosis of Lyme disease
US4835099A (en) * 1986-11-20 1989-05-30 Becton, Dickinson And Company Signal enhancement in immunoassay by modulation of enzymatic catalysis
US5494793A (en) * 1986-12-15 1996-02-27 British Technology Group Usa Inc. Monomeric phthalocyanine reagents
US5346670A (en) * 1986-12-24 1994-09-13 British Technology Group U.S.A. Inc. Phthalocyanine and tetrabenztriazaporphyrin reagents
US5082627A (en) * 1987-05-01 1992-01-21 Biotronic Systems Corporation Three dimensional binding site array for interfering with an electrical field
EP0310361A3 (en) * 1987-09-30 1989-05-24 Beckman Instruments, Inc. Tridentate conjugate and method of use thereof
US4859612A (en) * 1987-10-07 1989-08-22 Hygeia Sciences, Inc. Metal sol capture immunoassay procedure, kit for use therewith and captured metal containing composite
US5256372A (en) * 1987-11-06 1993-10-26 Idexx Corporation Dipstick test device including a removable filter assembly
US5202267A (en) * 1988-04-04 1993-04-13 Hygeia Sciences, Inc. Sol capture immunoassay kit and procedure
US5374524A (en) * 1988-05-10 1994-12-20 E. I. Du Pont De Nemours And Company Solution sandwich hybridization, capture and detection of amplified nucleic acids
US5137804A (en) * 1988-05-10 1992-08-11 E. I. Du Pont De Nemours And Company Assay device and immunoassay
US5039607A (en) * 1988-05-17 1991-08-13 Syntex (U.S.A.) Inc. Method for immunochromatographic analysis
US5334513A (en) * 1988-05-17 1994-08-02 Syntex (U.S.A.) Inc. Method for immunochromatographic analysis
US5028535A (en) * 1989-01-10 1991-07-02 Biosite Diagnostics, Inc. Threshold ligand-receptor assay
US5939272A (en) * 1989-01-10 1999-08-17 Biosite Diagnostics Incorporated Non-competitive threshold ligand-receptor assays
US5196306A (en) * 1989-03-29 1993-03-23 E. I. Du Pont De Nemours And Company Method for the detection or quantitation of an analyte using an analyte dependent enzyme activation system
US5532138A (en) * 1990-04-26 1996-07-02 Behringwerke Ag Method and kits for determining peroxidatively active catalysts
US5143852A (en) * 1990-09-14 1992-09-01 Biosite Diagnostics, Inc. Antibodies to ligand analogues and their utility in ligand-receptor assays
CA2072758A1 (en) * 1990-09-14 1992-03-15 Kenneth Francis Buechler Antibodies to complexes of ligand receptors and ligands and their utility in ligand-receptor assays
DE4103167A1 (de) * 1991-02-02 1992-08-06 Boehringer Mannheim Gmbh Diphenylmethanderivate, verfahren zu deren herstellung und ihre verwendung zur verdraengung von jodthyroninen von diesen bindenden proteinen
US6251581B1 (en) * 1991-05-22 2001-06-26 Dade Behring Marburg Gmbh Assay method utilizing induced luminescence
US5340716A (en) * 1991-06-20 1994-08-23 Snytex (U.S.A.) Inc. Assay method utilizing photoactivated chemiluminescent label
US5578498A (en) 1991-05-22 1996-11-26 Behringwerke Ag Metal chelate containing compositions for use in chemiluminescent assays
US5998220A (en) * 1991-05-29 1999-12-07 Beckman Coulter, Inc. Opposable-element assay devices, kits, and methods employing them
US6168956B1 (en) 1991-05-29 2001-01-02 Beckman Coulter, Inc. Multiple component chromatographic assay device
US5877028A (en) * 1991-05-29 1999-03-02 Smithkline Diagnostics, Inc. Immunochromatographic assay device
EP0525723B1 (en) 1991-07-29 1997-05-14 Mochida Pharmaceutical Co., Ltd. Process and device for specific binding assay
EP0561626B1 (en) * 1992-03-17 1998-08-12 Unitika Ltd. A method for enzymatic analysis and reagent therefor
US5332662A (en) * 1992-07-31 1994-07-26 Syntex (U.S.A.) Inc. Methods for determining peroxidatively active substances
CA2141451C (en) * 1992-07-31 2003-10-07 John S. Pease Photoactivatable chemiluminescent matrices
US5354692A (en) * 1992-09-08 1994-10-11 Pacific Biotech, Inc. Analyte detection device including a hydrophobic barrier for improved fluid flow
US5869445A (en) * 1993-03-17 1999-02-09 University Of Washington Methods for eliciting or enhancing reactivity to HER-2/neu protein
US6953573B1 (en) 1993-03-17 2005-10-11 University Of Washington Compounds for eliciting or enhancing immune reactivity to HER-2/neu protein for prevention or treatment of malignancies in which the HER-2/neu oncogene is associated
US5801005A (en) * 1993-03-17 1998-09-01 University Of Washington Immune reactivity to HER-2/neu protein for diagnosis of malignancies in which the HER-2/neu oncogene is associated
AU679008B2 (en) * 1993-05-06 1997-06-19 Chiron Diagnostics Corporation Mixed luminescent conjugate test assays
WO1995006877A1 (en) * 1993-09-03 1995-03-09 Behringwerke Ag Fluorescent oxygen channeling immunoassays
US7635597B2 (en) 1995-08-09 2009-12-22 Bayer Healthcare Llc Dry reagent particle assay and device having multiple test zones and method therefor
US6942862B2 (en) * 1996-04-01 2005-09-13 University Of Washington Methods and compositions to generate immunity in humans against self tumor antigens by immunization with homologous foreign proteins
DE69736382T2 (de) * 1996-05-01 2007-08-09 Dade Behring Marburg Gmbh Chemilumineszente zusammensetungen und ihre verwendung zum nachweis von wasserstoffperoxid
US5968839A (en) * 1996-05-13 1999-10-19 Metrika, Inc. Method and device producing a predetermined distribution of detectable change in assays
US6342349B1 (en) 1996-07-08 2002-01-29 Burstein Technologies, Inc. Optical disk-based assay devices and methods
US6331275B1 (en) 1996-07-08 2001-12-18 Burstein Technologies, Inc. Spatially addressable, cleavable reflective signal elements, assay device and method
WO1998001533A1 (en) 1996-07-08 1998-01-15 Burstein Laboratories, Inc. Cleavable signal element device and method
US6171801B1 (en) 1996-07-18 2001-01-09 Dade Behring Marburg Gmbh Methods for releasing a ligand from a complex
CA2231569A1 (en) * 1996-07-18 1998-01-29 Behringwerke Aktiengesellschaft Reagents for assays for mycophenolic acid
US5945345A (en) * 1996-08-27 1999-08-31 Metrika, Inc. Device for preventing assay interference using silver or lead to remove the interferant
GB9622524D0 (en) * 1996-10-29 1997-01-08 London Biotechnology Ltd Enzyme labels for assays
US5929049A (en) * 1997-08-08 1999-07-27 Dade Behring Marburg Gmbh Polysaccharide conjugates of biomolecules
US6007992A (en) * 1997-11-10 1999-12-28 Gilead Sciences, Inc. Pyrimidine derivatives for labeled binding partners
US6028183A (en) * 1997-11-07 2000-02-22 Gilead Sciences, Inc. Pyrimidine derivatives and oligonucleotides containing same
US6153442A (en) * 1998-05-20 2000-11-28 Dade Behring Inc. Reagents and methods for specific binding assays
US7347972B1 (en) 1998-07-22 2008-03-25 Jin Po Lee Multiple analyte assay device
EP1097378A2 (en) * 1998-07-21 2001-05-09 Burstein Laboratories Inc. Optical disc-based assay devices and methods
US6403807B1 (en) 1999-07-06 2002-06-11 Surromed, Inc. Bridged fluorescent dyes, their preparation and their use in assays
DK1234031T3 (en) 1999-11-30 2017-07-03 Mayo Foundation B7-H1, AN UNKNOWN IMMUNE REGULATORY MOLECULE
US6891030B2 (en) 2000-07-27 2005-05-10 Mayo Foundation For Medical Education And Research T-cell immunoregulatory molecule
WO2002043866A2 (en) * 2000-12-01 2002-06-06 Burstein Technologies, Inc. Apparatus and methods for separating components of particulate suspension
EP1493014A2 (en) 2001-04-11 2005-01-05 Burstein Technologies, Inc. Multi-parameter assays including analysis discs and methods relating thereto
WO2003027723A2 (en) * 2001-07-24 2003-04-03 Burstein Technologies, Inc. Method and apparatus for bonded fluidic circuit for optical bio-disc
US20030129665A1 (en) * 2001-08-30 2003-07-10 Selvan Gowri Pyapali Methods for qualitative and quantitative analysis of cells and related optical bio-disc systems
US20030143637A1 (en) * 2001-08-31 2003-07-31 Selvan Gowri Pyapali Capture layer assemblies for cellular assays including related optical analysis discs and methods
AU2002335715A1 (en) * 2001-09-07 2003-03-24 Burstein Technologies, Inc. Optical bio-disc systems for nuclear morphology based identification
AU2002352735A1 (en) * 2001-11-20 2003-06-10 Burstein Technologies, Inc. Optical bio-discs and microfluidic devices for analysis of cells
US6696254B2 (en) 2001-11-21 2004-02-24 Kimberly-Clark Worldwide, Inc. Detection and identification of enteric bacteria
DE60219207T2 (de) * 2001-12-12 2008-01-24 Proteome Systems Intellectual Property Pty. Ltd., North Ryde Diagnostisches testverfahren
WO2003057904A1 (en) * 2001-12-28 2003-07-17 Arkray, Inc. Method of colorimetry and reagent for use therein
WO2003057905A1 (en) * 2001-12-28 2003-07-17 Arkray, Inc. Method of colorimetry and reagent for use therein
US20040241381A1 (en) * 2002-01-31 2004-12-02 Chen Yihfar Microfluidic structures with circumferential grooves for bonding adhesives and related optical analysis discs
US20050023765A1 (en) * 2002-01-31 2005-02-03 Coombs James Howard Bio-safety features for optical analysis disc and disc system including same
WO2003064996A2 (en) * 2002-01-31 2003-08-07 Burstein Technologies, Inc. Bio-safe dispenser and optical analysis disc assembly
US20050221048A1 (en) * 2002-01-31 2005-10-06 James Rodney Norton Manufacturing processes for making optical analysis discs including successive patterning operations and optical discs thereby manufactured
SI2508596T1 (sl) 2002-02-21 2016-01-29 Institute Of Virology Slovak Academy Of Sciences Monoklonska protitelesa, specifična za MN/CA IX, proizvedena iz MN/CA IX deficientnih miši, in postopki uporabe
DE60328477D1 (de) * 2002-04-16 2009-09-03 Univ California Verfahren zur prognose von nierenzellkarzinom und behandlungsauswahl mit carboanhydrase ix
WO2004045364A2 (en) * 2002-05-15 2004-06-03 Mayo Foundation For Medical Education And Research Methods of detecting ovarian neoplasia
AU2003253606A1 (en) * 2002-05-20 2003-12-12 Regents Of The University Of California Methods and compositions for regulation and manipulation of steroidogenesis
AU2003239558A1 (en) * 2002-05-21 2003-12-12 Florida State University Methods and materials for treating inflammatory conditions
US20050221349A1 (en) * 2002-05-30 2005-10-06 Stuart Wilson Methods of detecting target molecules and molecular interactions
CA2518677A1 (en) * 2003-03-03 2004-12-09 Nagaoka & Co., Ltd. Methods and apparatus for use in detection and quantitation of various cell types and use of optical bio-disc for performing same
US20050037484A1 (en) * 2003-04-23 2005-02-17 Norbert Staimer Optical bio-discs including spiral fluidic circuits for performing assays
WO2004113871A2 (en) * 2003-06-19 2004-12-29 Nagaoka & Co., Ltd. Fluidic circuits for sample preparation including bio-discs and methods relating thereto
US7390464B2 (en) * 2003-06-19 2008-06-24 Burstein Technologies, Inc. Fluidic circuits for sample preparation including bio-discs and methods relating thereto
WO2005000095A2 (en) 2003-06-20 2005-01-06 Mayo Foundation For Medical Education And Research Isoforms of brain natriuretic peptide
EP1644184A2 (en) * 2003-06-27 2006-04-12 Nagaoka & Co., Ltd. Fluidic circuits, methods and apparatus for use of whole blood samples in colorimetric assays
WO2005006949A2 (en) * 2003-07-07 2005-01-27 Wagner David H Methods for predicting development of auto-immune diseases and treatment of same
JP2007500351A (ja) * 2003-07-25 2007-01-11 長岡実業株式会社 バイオディスクを有するサンプル調製用流体回路及びそれに関連した方法
ATE447412T1 (de) 2003-11-04 2009-11-15 Novartis Vaccines & Diagnostic Antagonist-anti-cd40-monoklonale antikörper und anwendungsverfahren
SI1682177T1 (sl) 2003-11-04 2010-12-31 Novartis Vaccines & Diagnostic Uporaba antagonističnih anti-CD40 protiteles za zdravljenje kronične limfocitne levkemije
KR101128777B1 (ko) 2003-11-04 2012-04-13 조마 테크놀로지 리미티드 다발성 골수종을 치료하기 위한 길항제 항-ｃｄ４０단클론성 항체의 용도
PL1680141T3 (pl) 2003-11-04 2011-04-29 Novartis Vaccines & Diagnostics Inc Sposoby leczenia guzów litych wykazujących ekspresję antygenu powierzchniowego CD40
JP3615752B1 (ja) 2003-11-18 2005-02-02 淳 高橋 細径樹脂捩じりブラシ
US6991911B2 (en) 2003-12-15 2006-01-31 Dade Behring Inc. Assay for entactogens
US7022492B2 (en) 2003-12-15 2006-04-04 Dade Behring Inc. Ecstasy haptens and immunogens
US7150995B2 (en) 2004-01-16 2006-12-19 Metrika, Inc. Methods and systems for point of care bodily fluid analysis
DK1810026T3 (en) 2004-10-06 2018-07-16 Mayo Found Medical Education & Res B7-H1 AND PD-1 FOR TREATMENT OF RENAL CELL CARCINOM
WO2006048262A2 (en) * 2004-11-04 2006-05-11 Roche Diagnostics Gmbh Classification of acute myeloid leukemia
US7842794B2 (en) 2004-12-17 2010-11-30 Roche Molecular Systems, Inc. Reagents and methods for detecting Neisseria gonorrhoeae
US8323977B2 (en) 2005-01-28 2012-12-04 State Of Oregon Acting By And Through The State Board Of Higher Education On Behalf Of Portland State University Method for determining redox activity and screening compounds based on redox activity
US20060188997A1 (en) * 2005-01-28 2006-08-24 Portland State University Detection of superoxide ions
US8017401B2 (en) * 2005-01-28 2011-09-13 State Of Oregon Acting By And Through The State Board Of Higher Education On Behalf Of Portland State University Method for determining redox activity and screening compounds based on redox activity
EP1848981A4 (en) * 2005-02-09 2012-01-18 Oregon State METHOD FOR DETERMINING REDOX ACTIVITY AND SCREENING COMPOUNDS BASED ON REDOX ACTIVITY
US20060182722A1 (en) * 2005-02-11 2006-08-17 Hering Bernhard J Methods and materials for isolating isogenic islet cells
WO2006089125A2 (en) * 2005-02-16 2006-08-24 Dana-Farber Cancer Institute Methods of detecting ovarian cancer
US7189582B2 (en) 2005-04-27 2007-03-13 Dade Behring Inc. Compositions and methods for detection of sirolimus
WO2006125021A2 (en) * 2005-05-16 2006-11-23 Dana Farber Cancer Institute, Inc. Fibrinogen alpha and hemoglobin polypeptides as cancer markers
JP5421590B2 (ja) 2005-05-18 2014-02-19 ノバルティス アーゲー 自己免疫および／または炎症性成分を有する疾患の診断および治療のための方法
CA2611861C (en) 2005-06-08 2017-11-28 The Brigham And Women's Hospital, Inc. Methods and compositions for the treatment of persistent infections
US7695975B2 (en) 2005-06-23 2010-04-13 Siemens Healthcare Diagnostics Inc. Detection of adulterated samples
US20070037174A1 (en) * 2005-08-12 2007-02-15 Rampal Jang B Chemiluminescent generated fluorescent labeling
US8119358B2 (en) 2005-10-11 2012-02-21 Tethys Bioscience, Inc. Diabetes-related biomarkers and methods of use thereof
CA2625744A1 (en) 2005-10-11 2007-04-19 Tethys Bioscience, Inc. Diabetes-associated markers and methods of use thereof
EP2674757A3 (en) * 2005-11-12 2014-03-05 Platform Diagnostics Limited Agglutination assay
US9121853B2 (en) * 2006-03-20 2015-09-01 Mayo Foundation For Medical Education And Research B7-H4 expression on tumor vasculature
AR060487A1 (es) 2006-04-21 2008-06-18 Xoma Technology Ltd Composiciones farmaceuticas de antagonistas del anticuerpo anti- cd40
US7799534B2 (en) 2006-05-09 2010-09-21 Beckman Coulter, Inc. Nonseparation assay methods
US7732153B2 (en) 2006-05-09 2010-06-08 Beckman Coulter, Inc. Nonseparation assay methods
US20080057590A1 (en) 2006-06-07 2008-03-06 Mickey Urdea Markers associated with arteriovascular events and methods of use thereof
CN101501067B (zh) * 2006-08-08 2013-01-16 梅约医学教育与研究基金会 利尿和利尿钠的多肽
US20100267052A1 (en) * 2006-09-01 2010-10-21 American Type Culture Collection Compositions and methods for diagnosis and treatment of type 2 diabetes
US7951776B2 (en) * 2006-09-01 2011-05-31 American Type Culture Collection Methods for treatment of type 1 diabetes
US20090203602A1 (en) * 2006-09-01 2009-08-13 Cohava Gelber Compositions and methods for diagnosis and treatment of type 2 diabetes
US20080300170A1 (en) * 2006-09-01 2008-12-04 Cohava Gelber Compositions and methods for diagnosis and treatment for type 2 diabetes
US8283318B2 (en) 2006-09-08 2012-10-09 Mayo Foundation For Medical Education And Research Aquaretic and natriuretic polypeptides lacking vasodilatory activity
BRPI0717416A2 (pt) 2006-09-21 2013-11-12 Prometheus Lab Inc Método para realizar um imunoensaio complexo de alta produtividade, e, arranjo
US7989173B2 (en) 2006-12-27 2011-08-02 The Johns Hopkins University Detection and diagnosis of inflammatory disorders
GB0700133D0 (en) 2007-01-04 2007-02-14 Humabs Llc Human cytomegalovirus neutralising antibodies and use thereof
EP2121750A2 (en) * 2007-01-16 2009-11-25 Wyeth Inflammation treatment, detection and monitoring via trem-1
CA2684308A1 (en) 2007-04-18 2008-10-30 Tethys Bioscience, Inc. Diabetes-related biomarkers and methods of use thereof
CN101971033A (zh) 2007-06-04 2011-02-09 戴诺普雷克斯公司 用于结直肠癌的生物标志物组合
EP2179291B1 (en) * 2007-07-13 2014-10-22 Nestec S.A. Drug selection for lung cancer therapy using antibody-based arrays
CN101541957B (zh) 2007-07-20 2013-08-14 梅约医学教育与研究基金会 利尿钠多肽
US7790401B2 (en) 2007-08-06 2010-09-07 Siemens Healthcare Diagnostics Methods for detection of immunosuppressant drugs
WO2009036448A2 (en) * 2007-09-15 2009-03-19 Mayo Foundation For Medical Education And Research Natriuretic peptide receptor-c agonists
US20100240070A1 (en) * 2007-11-07 2010-09-23 Beckman Coulter, Inc. Nonseparation Assay Methods Using Peroxide Generating Enzymes
US7910378B2 (en) 2007-12-14 2011-03-22 Siemens Healthcare Diagnostics Inc. Methods for detection of hydrophobic drugs
AU2009219437B2 (en) * 2008-02-25 2014-10-16 Nestec S.A. Drug selection for breast cancer therapy using antibody-based arrays
AU2009262022A1 (en) * 2008-06-26 2009-12-30 Dana-Farber Cancer Institute, Inc. Signatures and determinants associated with metastasis and methods of use thereof
US8741842B2 (en) * 2008-07-02 2014-06-03 Mayo Foundation For Medical Education And Research Chimeric natriuretic polypeptides with unique pharmacologic profiles
EP2315858A2 (en) 2008-07-08 2011-05-04 Source Precision Medicine, Inc. Gene expression profiling for predicting the survivability of prostate cancer subjects
AU2008359583B2 (en) 2008-07-16 2012-04-05 Institute For Research In Biomedicine Human cytomegalovirus neutralising antibodies and use thereof
DK2352759T3 (en) 2008-07-16 2017-12-18 Inst Res Biomedicine ANTIBODIES THAT NEUTRALIZE HUMAN CYTOMEGALOVIRUS AND USE THEREOF
EP2321647B1 (en) 2008-07-17 2013-09-04 IKFE Institut für klinische Forschung und Entwicklung GmbH Biomarkers for insulin resistance and beta-cell dysfunction
ES2437610T3 (es) 2008-07-17 2014-01-13 Ikfe Institut Für Klinische Forschung Und Entwicklung Gmbh Biomarcadores para cardiodiabetes
CA2731686C (en) * 2008-07-25 2020-04-07 Institute For Research In Biomedicine Neutralizing anti-influenza a virus antibodies and uses thereof
US8871207B2 (en) 2008-07-25 2014-10-28 Humabs, LLC Neutralizing anti-influenza A virus antibodies and uses thereof
US8642550B2 (en) 2008-10-24 2014-02-04 Mayo Foundation For Medical Education And Research Chimeric natriuretic peptides without hypotensive inducing capability
US20100183633A1 (en) * 2008-12-04 2010-07-22 University Of Massachusetts Interleukin 6 and tumor necrosis factor alpha as biomarkers of jnk inhibition
CA2782776A1 (en) 2008-12-04 2010-06-10 Ikfe Gmbh Biomarkers for atherosclerosis
AU2009325962A1 (en) 2008-12-11 2011-07-28 Ikfe Institut Fur Klinische Forschung Und Entwicklung Gmbh Biomarkers for insulin sensitizer drug response
US8455438B2 (en) 2008-12-29 2013-06-04 Mayo Foundation For Medical Education And Research Natriuretic polypeptides for reducing or preventing restenosis
US8455263B2 (en) 2008-12-30 2013-06-04 Jin Po Lee Quantitative analyte assay device and method
EP2382467A1 (en) 2008-12-30 2011-11-02 IKFE GmbH Biomarkers for adipose tissue activity
US20100210541A1 (en) 2009-01-07 2010-08-19 Andreas Pfuetzner Biomarkers for Appetite Regulation
WO2010091206A1 (en) 2009-02-04 2010-08-12 Massachusetts Institute Of Technology Compositions and uses to govern cancer cell growth
US20120108514A1 (en) 2009-07-09 2012-05-03 University Of Iowa Research Foundation Long acting atrial natriuretic peptide (la-anp) and methods for use thereof
JP5795311B2 (ja) 2009-07-15 2015-10-14 ネステク ソシエテ アノニム 抗体ベースのアレイを使用する胃癌療法のための薬物選択
CA2772204A1 (en) 2009-08-31 2011-03-03 Amplimmune, Inc. Methods and compositions for the inhibition of transplant rejection
WO2011047358A1 (en) 2009-10-15 2011-04-21 Crescendo Bioscience Biomarkers and methods for measuring and monitoring inflammatory disease activity
EP2494364A1 (en) 2009-10-29 2012-09-05 Tethys Bioscience, Inc. Protein and lipid biomarkers providing consistent improvement to the prediction of type 2 diabetes
JP2013509587A (ja) 2009-10-29 2013-03-14 テシス バイオサイエンス， インコーポレイテッド 糖尿病のリスクを決定する方法
WO2011058367A2 (en) 2009-11-13 2011-05-19 Astrazeneca Ab Diagnostic test for predicting responsiveness to treatment with poly(adp-ribose) polymerase (parp) inhibitor
US20130183326A9 (en) 2009-11-20 2013-07-18 St. Jude Children's Research Hospital Methods and compositions for modulating the activity of the interleukin-35 receptor complex
US9709565B2 (en) 2010-04-21 2017-07-18 Memed Diagnostics Ltd. Signatures and determinants for distinguishing between a bacterial and viral infection and methods of use thereof
US8329424B2 (en) 2010-06-25 2012-12-11 Siemens Healthcare Diagnostics Reduction in false results in assay measurements
US8956859B1 (en) 2010-08-13 2015-02-17 Aviex Technologies Llc Compositions and methods for determining successful immunization by one or more vaccines
US10088490B2 (en) 2010-08-20 2018-10-02 Siemens Healthcare Diagnostics Inc. Assay for analytes using multiple receptors
CA2815416A1 (en) 2010-10-21 2012-04-26 Vertex Pharmaceuticals Incorporated Biomarkers for hcv infected patients
WO2012075111A1 (en) 2010-11-30 2012-06-07 Novartis Ag Uses of anti-cd40 antibodies in combination therapy for b cell-related cancers
US9719995B2 (en) 2011-02-03 2017-08-01 Pierian Holdings, Inc. Drug selection for colorectal cancer therapy using receptor tyrosine kinase profiling
AU2011373387B2 (en) 2011-07-18 2017-06-29 Institute For Research In Biomedicine Neutralizing anti-influenza A virus antibodies and uses thereof
EP2742352B1 (en) 2011-08-12 2018-02-28 Siemens Healthcare Diagnostics Inc. Detection of sex steroids
CN103906761B (zh) 2011-08-30 2016-12-21 梅约医学教育与研究基金会 利钠多肽
EP2751562B1 (en) 2011-09-02 2015-09-16 Nestec S.A. Profiling of signal pathway proteins to determine therapeutic efficacy
WO2013071066A1 (en) 2011-11-11 2013-05-16 The Broad Institute, Inc. Signatures associated with the response to cancer therapy
WO2013103896A1 (en) 2012-01-06 2013-07-11 Mayo Foundation For Medical Education And Research Treating cardiovascular or renal diseases
US8771964B2 (en) 2012-02-02 2014-07-08 Siemens Healthcare Diagnostics Inc. Compositions and methods for detection of methadone metabolite
CN108802385B (zh) 2012-02-09 2022-02-08 米密德诊断学有限公司 用于诊断感染的标记和决定因素和其使用方法
CN104350069B (zh) 2012-03-20 2017-12-01 胡默波斯生物医学公司 中和rsv、mpv和pvm的抗体和其应用
US20140186859A1 (en) 2012-05-09 2014-07-03 Advanced Animal Diagnostic, Inc. Autofocus method for imaging a biological sample and cartridge for use therein
CN107674071B (zh) 2012-05-11 2021-12-31 同步制药公司 作为隐花色素调节剂的含有咔唑的磺酰胺类
ES2704857T3 (es) 2012-06-27 2019-03-20 Siemens Healthcare Diagnostics Inc Composiciones y métodos para la evaluación de la mezcla de líquidos
WO2014015217A1 (en) 2012-07-19 2014-01-23 Vertex Pharmaceuticals Incorporated Biomarkers for hcv infected patients
WO2014028569A1 (en) 2012-08-15 2014-02-20 The Procter & Gamble Company Systems, models and methods for identifying and evaluating skin-active agents effective for treating an array of skin disorders
US10288626B2 (en) 2012-09-14 2019-05-14 University Of Kentucky Research Foundation Secreted tumor-associated cytochrome as a blood-based biomarker for cancer
US9244083B2 (en) 2012-11-30 2016-01-26 Siemens Healthcare Diagnostics Inc. Compositions and methods for detecting vitamin D
US9121859B2 (en) 2012-12-04 2015-09-01 Siemens Healthcare Diagnostics Inc. Compounds and methods for determination of FKBP-binding immunosuppressant drugs
EP2948471A4 (en) 2013-01-24 2016-08-10 Mayo Foundation METHOD AND MATERIALS FOR DETECTING POSITIVE FRONTOTEMPORAL PAPER DEGENERATION BY C9ORF72 HEXANUCLEOTIDE REPEAT EXPANSION OR AMYOTROPHATE LATERAL SCLEROSIS BY C9ORF72 HEXANUCLEOTIDE REPEAT EXPANSION
US9302005B2 (en) 2013-03-14 2016-04-05 Mayo Foundation For Medical Education And Research Methods and materials for treating cancer
US20140308751A1 (en) 2013-04-12 2014-10-16 Siemens Healthcare Diagnostics Inc. Assays for Analyte Homologs
HK1213296A1 (zh) * 2013-06-04 2016-06-30 豪夫迈‧罗氏有限公司 用於fret的新化合物及与其相关的方法
ES2714708T3 (es) 2013-10-01 2019-05-29 Mayo Found Medical Education & Res Procedimientos para el tratamiento de cáncer en pacientes con niveles elevados de Bim
SI3052192T1 (sl) 2013-10-02 2020-11-30 Medimmune, Llc Nevtralizarijoča protitelesa proti-influenci A in njihove uporabe
WO2015051304A1 (en) 2013-10-04 2015-04-09 Aptose Biosciences Inc. Compositions, biomarkers and their use in treatment of cancer
US20160252507A1 (en) 2013-10-24 2016-09-01 Siemens Healthcare Diagnostics Inc. Assays for macromolecular analytes
ES2740851T3 (es) 2013-12-13 2020-02-06 Siemens Healthcare Diagnostics Inc Agente de tratamiento previo en ensayos sin aglutinación
EP3084437B1 (en) 2013-12-18 2018-02-28 Siemens Healthcare Diagnostics Inc. Detection of endothelial disease
CN106459993A (zh) 2014-03-31 2017-02-22 德彪药业国际股份公司 Fgfr融合体
WO2015153437A1 (en) 2014-04-02 2015-10-08 Crescendo Bioscience Biomarkers and methods for measuring and monitoring juvenile idiopathic arthritis activity
TWI690521B (zh) 2014-04-07 2020-04-11 美商同步製藥公司 作為隱花色素調節劑之含有咔唑之醯胺類、胺基甲酸酯類及脲類
US9176113B1 (en) 2014-04-11 2015-11-03 Synapdx Corporation Methods and systems for determining autism spectrum disorder risk
US10302653B2 (en) 2014-05-22 2019-05-28 Mayo Foundation For Medical Education And Research Distinguishing antagonistic and agonistic anti B7-H1 antibodies
CA2950771A1 (en) 2014-06-10 2015-12-17 Crescendo Bioscience Biomarkers and methods for measuring and monitoring axial spondyloarthritis disease activity
WO2015200182A1 (en) 2014-06-27 2015-12-30 Siemens Healthcare Diagnostics Inc. Binding partners specific for vitamin d epimers
CN106661114B (zh) 2014-06-27 2019-01-29 西门子医疗保健诊断公司 维生素d测定法中对维生素d差向异构体特异性的结合配偶体
MX392761B (es) 2014-07-15 2025-03-21 Medimmune Llc Anticuerpos anti-influenza b neutralizantes y usos de los mismos.
WO2016014148A1 (en) 2014-07-23 2016-01-28 Mayo Foundation For Medical Education And Research Targeting dna-pkcs and b7-h1 to treat cancer
BR112017002884A2 (pt) 2014-08-14 2018-01-30 Memed Diagnostics Ltd ?análise computacional de dados biológicos por meio do uso de variedade e hiperplano?
US20170296650A1 (en) 2014-10-08 2017-10-19 Novartis Ag Combination of human cytomegalovirus neutralizing antibodies
WO2016075546A2 (en) 2014-11-14 2016-05-19 Antonio Lanzavecchia Antibodies that neutralize ebola virus and uses thereof
SI3220947T1 (sl) 2014-11-18 2021-02-26 Humabs Biomed S.A. Protitelesa, ki močno nevtralizirajo virus stekline in druge lisaviruse in njihove uporabe
CN107209184B (zh) 2014-12-11 2020-04-24 米密德诊断学有限公司 用于诊断多种感染的标记组合及其使用方法
HUE056407T2 (hu) 2015-06-01 2022-02-28 Medimmune Llc Neutralizáló influenzaellenes kötõmolekulák és alkalmazásaik
WO2016207402A1 (en) 2015-06-26 2016-12-29 Institute For Research In Biomedicine Proteins comprising a mutated lair-1 fragment and uses thereof
WO2017059003A1 (en) 2015-09-29 2017-04-06 Crescendo Bioscience Biomarkers and methods for assessing psoriatic arthritis disease activity
WO2017058999A2 (en) 2015-09-29 2017-04-06 Crescendo Bioscience Biomarkers and methods for assessing response to inflammatory disease therapy withdrawal
WO2017059878A1 (en) 2015-10-07 2017-04-13 Humabs Biomed Sa Antibodies that potently neutralize hepatitis b virus and uses thereof
WO2017075045A2 (en) 2015-10-30 2017-05-04 Mayo Foundation For Medical Education And Research Antibodies to b7-h1
SG11201805001UA (en) 2016-01-13 2018-07-30 Medimmune Llc Method of treating influenza a
CA3021343C (en) 2016-04-20 2024-05-28 Crescendo Bioscience Biomarkers and methods for assessing response to inflammatory disease therapy
CA3027341A1 (en) 2016-07-10 2018-01-18 Memed Diagnostics Ltd. Protein signatures for distinguishing between bacterial and viral infections
WO2018011796A1 (en) 2016-07-10 2018-01-18 Memed Diagnostics Ltd. Early diagnosis of infections
WO2018010789A1 (en) 2016-07-13 2018-01-18 Humabs Biomed Sa Novel antibodies specifically binding to zika virus epitopes and uses thereof
EP3504553B1 (en) 2016-08-10 2022-04-20 Memed Diagnostics Ltd. System and method for analysis of biological data
WO2018193063A2 (en) 2017-04-19 2018-10-25 Institute For Research In Biomedicine Novel malaria vaccines and antibodies binding to plasmodium sporozoites
US10696899B2 (en) 2017-05-09 2020-06-30 International Business Machines Corporation Light emitting shell in multi-compartment microcapsules
US10900908B2 (en) * 2017-05-24 2021-01-26 International Business Machines Corporation Chemiluminescence for tamper event detection
US10357921B2 (en) 2017-05-24 2019-07-23 International Business Machines Corporation Light generating microcapsules for photo-curing
US10392452B2 (en) 2017-06-23 2019-08-27 International Business Machines Corporation Light generating microcapsules for self-healing polymer applications
WO2019042555A1 (en) 2017-08-31 2019-03-07 Humabs Biomed Sa MULTISPECIFIC ANTIBODIES SPECIFICALLY BINDING TO ZIKA VIRUS EPITOPES AND USES THEREOF
WO2019055609A1 (en) 2017-09-14 2019-03-21 University Of Alabama At Birmingham BIOMARKERS AND METHODS OF RISK ASSESSMENT OF MYOCARDIAL INFARCTION AND SEVERE INFECTION IN PATIENTS WITH RHEUMATOID ARTHRITIS
WO2019161129A1 (en) 2018-02-14 2019-08-22 Mayo Foundation For Medical Education And Research Rescuing cancer patients from resistance to treatment with inhibitors of pd-1/pd-l1 interactions
WO2020092839A1 (en) 2018-10-31 2020-05-07 Mayo Foundation For Medical Education And Research Methods and materials for treating cancer
EP3873540A4 (en) 2018-10-31 2022-07-27 Mayo Foundation for Medical Education and Research METHODS AND MATERIALS FOR THE TREATMENT OF CANCER
JP2022506683A (ja) 2018-11-04 2022-01-17 フィジーン、エルエルシー 膵臓移植のファシリテーターとして繊維芽細胞を用いる１型糖尿病の治療方法および組成物
FI3898668T3 (fi) 2018-12-19 2023-11-28 Humabs Biomed Sa B-hepatiittivirusta neutraloivia vasta-aineita ja niiden käyttöjä
CA3152511A1 (en) 2019-08-29 2021-03-04 Vir Biotechnology, Inc. Antibody compositions and methods for treating hepatitis b virus infection
CN118465272B (zh) 2019-12-04 2025-08-19 珠海泰诺麦博制药股份有限公司 抗人巨细胞病毒抗体及其用途
IL295179A (en) 2020-01-29 2022-09-01 Memed Diagnostics Ltd Methods for diagnosis and classification of viral infections
PH12022553569A1 (en) 2020-06-24 2023-04-12 Humabs Biomed Sa Engineered hepatitis b virus neutralizing antibodies and uses thereof
AU2021389671A1 (en) 2020-11-24 2023-06-22 Monash University Induced stem cells
JP2024504167A (ja) 2021-01-26 2024-01-30 ヴィア・バイオテクノロジー・インコーポレイテッド Ｂ型肝炎ウイルス感染を処置するための抗体組成物および方法
JP2024509973A (ja) 2021-03-10 2024-03-05 マビュロン アーゲー Ｔｄｐ－４３に対する抗体およびその使用方法
GB2613386A (en) 2021-12-02 2023-06-07 Apis Assay Tech Limited Diagnostic test
GB202203588D0 (en) 2022-03-15 2022-04-27 Argonaut Therapeutics Ltd Cancer diagnostic
WO2024261762A2 (en) 2023-06-21 2024-12-26 Metasight Diagnostics Ltd Liver fibrosis, nash and "at-risk" nash biomarkers and methods
US12427185B2 (en) 2023-09-05 2025-09-30 E-Star Biotech, LLC Formulations of MANP and uses thereof
GB202316762D0 (en) 2023-11-01 2023-12-13 Rna Guardian Ltd Determination of cancer status
WO2026009223A1 (en) 2024-07-02 2026-01-08 Yeda Research And Development Co. Ltd. Computational methods for mapping peptides using metagenomic data
WO2026083423A1 (en) 2024-10-20 2026-04-23 Metasight Diagnostics Ltd Biomarker for diagnosing and monitoring liver fibrosis and nash

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL154599B (nl) * 1970-12-28 1977-09-15 Organon Nv Werkwijze voor het aantonen en bepalen van specifiek bindende eiwitten en hun corresponderende bindbare stoffen, alsmede testverpakking.
US3690834A (en) * 1971-01-11 1972-09-12 Syva Co Ligand determination with spin labeled compounds by receptor displacement
US3817837A (en) * 1971-05-14 1974-06-18 Syva Corp Enzyme amplification assay
US3852157A (en) * 1971-05-14 1974-12-03 Syva Corp Compounds for enzyme amplification assay
DE2440367C2 (de) * 1973-08-30 1984-03-15 General Electric Co., Schenectady, N.Y. Verfahren zum Herstellen multimolekularer Schichten aus immunologisch komplexierten Proteinen auf einem Substrat
SE388694B (sv) * 1975-01-27 1976-10-11 Kabi Ab Sett att pavisa ett antigen exv i prov av kroppvetskor, med utnyttjande av till porost berarmaterial bundna eller adsorberande antikroppar
IN142734B (https=) * 1975-04-28 1977-08-20 Miles Lab
US4181650A (en) * 1975-08-25 1980-01-01 Maier Charles L Jr Procedure for the assay of pharmacologically immunologically and biochemically active compounds in biological fluids
US4080264A (en) * 1976-03-01 1978-03-21 Massachusetts Institute Of Technology Immunoassay by light scattering spectroscopy

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US4233402A (en) 1980-11-11
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