FR2423490A1 - Nouveaux 4-oxo-4h-pyrido(1,2-a)pyrimidine-3-n-(1h-tetrazol-5-yl) carboxamides eventuellement substitues, leur procede de production et medicament les contenant - Google Patents
Nouveaux 4-oxo-4h-pyrido(1,2-a)pyrimidine-3-n-(1h-tetrazol-5-yl) carboxamides eventuellement substitues, leur procede de production et medicament les contenantInfo
- Publication number
- FR2423490A1 FR2423490A1 FR7907971A FR7907971A FR2423490A1 FR 2423490 A1 FR2423490 A1 FR 2423490A1 FR 7907971 A FR7907971 A FR 7907971A FR 7907971 A FR7907971 A FR 7907971A FR 2423490 A1 FR2423490 A1 FR 2423490A1
- Authority
- FR
- France
- Prior art keywords
- tetrazol
- pyrido
- oxo
- new
- pyrimidine
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- -1 1H-TETRAZOL-5-YL Chemical class 0.000 title 1
- 150000003857 carboxamides Chemical class 0.000 title 1
- 238000004519 manufacturing process Methods 0.000 title 1
- 229940126601 medicinal product Drugs 0.000 title 1
- 206010020751 Hypersensitivity Diseases 0.000 abstract 1
- 230000003266 anti-allergic effect Effects 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 239000003112 inhibitor Substances 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/72—Nitrogen atoms
- C07D213/73—Unsubstituted amino or imino radicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/72—Nitrogen atoms
- C07D213/74—Amino or imino radicals substituted by hydrocarbon or substituted hydrocarbon radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/72—Nitrogen atoms
- C07D213/75—Amino or imino radicals, acylated by carboxylic or carbonic acids, or by sulfur or nitrogen analogues thereof, e.g. carbamates
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Pulmonology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Immunology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Pyridine Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US05/892,714 US4192944A (en) | 1978-04-03 | 1978-04-03 | Optionally substituted 4-oxo-4H-pyrido[1,2-a]pyrimidine-3-N-(1H-tetrazol-4-yl)carboxamides and their use as antiallergy agents |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| FR2423490A1 true FR2423490A1 (fr) | 1979-11-16 |
| FR2423490B1 FR2423490B1 (OSRAM) | 1982-03-19 |
Family
ID=25400392
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| FR7907971A Granted FR2423490A1 (fr) | 1978-04-03 | 1979-03-29 | Nouveaux 4-oxo-4h-pyrido(1,2-a)pyrimidine-3-n-(1h-tetrazol-5-yl) carboxamides eventuellement substitues, leur procede de production et medicament les contenant |
Country Status (15)
| Country | Link |
|---|---|
| US (1) | US4192944A (OSRAM) |
| JP (1) | JPS54141797A (OSRAM) |
| BE (1) | BE875246A (OSRAM) |
| CA (1) | CA1117112A (OSRAM) |
| CH (1) | CH643256A5 (OSRAM) |
| DE (1) | DE2913295A1 (OSRAM) |
| DK (1) | DK153485C (OSRAM) |
| FR (1) | FR2423490A1 (OSRAM) |
| GB (1) | GB2019836B (OSRAM) |
| IE (1) | IE48278B1 (OSRAM) |
| IT (1) | IT1116537B (OSRAM) |
| LU (1) | LU81107A1 (OSRAM) |
| NL (1) | NL7902444A (OSRAM) |
| SE (1) | SE440652B (OSRAM) |
| ZA (1) | ZA791525B (OSRAM) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4495189A (en) * | 1975-11-27 | 1985-01-22 | Chinoin Gyogyszer Es Vegyeszeti Termekek Gyara R.T. | Condensed pyrimidines |
| HU173438B (hu) * | 1975-11-27 | 1979-05-28 | Chinoin Gyogyszer Es Vegyeszet | Sposob poluchenija novykh proizvodnykh 4-okso-1,6,7,8-/tetragidro-4h-pirido/1,2/pirimidina s zaderzhivajuhhejj vozgoranie aktivnot'ju i protivosvertivajuhhem effektom |
| CA1157858A (en) | 1979-12-03 | 1983-11-29 | Ikuo Ueda | Quinazoline derivatives |
| IE51802B1 (en) * | 1979-12-03 | 1987-04-01 | Fujisawa Pharmaceutical Co | Quinazoline derivatives,processes for their preparation and pharmaceutical compositions containing them |
| JPS63183581A (ja) * | 1985-10-03 | 1988-07-28 | Tokyo Tanabe Co Ltd | ピリド〔１，２−ａ〕ピリミジン誘導体、その製造法及びそれを有効成分とするアレルギ−疾患治療薬 |
| HU201551B (en) * | 1988-02-03 | 1990-11-28 | Chinoin Gyogyszer Es Vegyeszet | Process for producing 4-oxo-4h-pyrido(1,2-a)pyrimidine-3-carboxylic acid amide derivatives and pharmaceutical compositions comprising same |
| US6295995B1 (en) * | 2000-04-07 | 2001-10-02 | Irene D. Ewaka | Permanently covered rigid or semi-rigid mounting piece for an article of fashion |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2319363A1 (fr) * | 1975-08-01 | 1977-02-25 | Pfizer | N-(5-tetrazolyl)-1-oxo-1h-6-alcoxypyrimido (1,2-a) quinoleine-2-carboxamides anti-allergiques et intermediaires appropries |
| FR2401159A1 (fr) * | 1977-05-25 | 1979-03-23 | Bristol Myers Co | Derives de 3-(1h-tetrazol-5-yl)-4h-pyrido(1,2-a)pyrimidine-4-one, leur procede de preparation et leur activite therapeutique |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3072485A (en) * | 1960-08-24 | 1963-01-08 | Eastman Kodak Co | Optically sensitized azido polymers for photomechanical resist compositions |
| AT302311B (de) * | 1966-11-02 | 1972-09-15 | Chinoin Gyogyszer Es Vegyeszet | Verfahren zur herstellung von homopyrimidazol-derivaten und deren saeureadditionssalzen und quaternaeren ammoniumsalzen |
| US3960847A (en) * | 1972-04-17 | 1976-06-01 | E. R. Squibb & Sons, Inc. | 9-Substituted-4-oxopyrido(1,2-α)pyrimidine-3-carboxylic acids and derivatives thereof |
| US3929787A (en) * | 1974-04-22 | 1975-12-30 | Squibb & Sons Inc | 6,7,8,9-Tetrahydro-pyrido(1,2-a)pyrimidin-4-ones |
| US4017625A (en) * | 1975-08-01 | 1977-04-12 | Pfizer Inc. | Anti-allergic N-(5-tetrazolyl)-1-oxo-1H-6-alkoxypyrimido-[1,2-a]quinoline-2-carboxamides and intermediates therefor |
| HU173438B (hu) * | 1975-11-27 | 1979-05-28 | Chinoin Gyogyszer Es Vegyeszet | Sposob poluchenija novykh proizvodnykh 4-okso-1,6,7,8-/tetragidro-4h-pirido/1,2/pirimidina s zaderzhivajuhhejj vozgoranie aktivnot'ju i protivosvertivajuhhem effektom |
-
1978
- 1978-04-03 US US05/892,714 patent/US4192944A/en not_active Expired - Lifetime
-
1979
- 1979-03-15 GB GB7909146A patent/GB2019836B/en not_active Expired
- 1979-03-29 NL NL7902444A patent/NL7902444A/xx not_active Application Discontinuation
- 1979-03-29 FR FR7907971A patent/FR2423490A1/fr active Granted
- 1979-03-29 DK DK130079A patent/DK153485C/da active
- 1979-03-30 ZA ZA791525A patent/ZA791525B/xx unknown
- 1979-03-30 BE BE0/194348A patent/BE875246A/xx not_active IP Right Cessation
- 1979-03-30 CA CA000324712A patent/CA1117112A/en not_active Expired
- 1979-04-02 SE SE7902915A patent/SE440652B/sv not_active IP Right Cessation
- 1979-04-02 LU LU81107A patent/LU81107A1/xx unknown
- 1979-04-02 IT IT48569/79A patent/IT1116537B/it active
- 1979-04-03 DE DE19792913295 patent/DE2913295A1/de active Granted
- 1979-04-03 JP JP3942779A patent/JPS54141797A/ja active Granted
- 1979-04-03 CH CH310379A patent/CH643256A5/de not_active IP Right Cessation
- 1979-08-08 IE IE950/79A patent/IE48278B1/en not_active IP Right Cessation
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2319363A1 (fr) * | 1975-08-01 | 1977-02-25 | Pfizer | N-(5-tetrazolyl)-1-oxo-1h-6-alcoxypyrimido (1,2-a) quinoleine-2-carboxamides anti-allergiques et intermediaires appropries |
| FR2401159A1 (fr) * | 1977-05-25 | 1979-03-23 | Bristol Myers Co | Derives de 3-(1h-tetrazol-5-yl)-4h-pyrido(1,2-a)pyrimidine-4-one, leur procede de preparation et leur activite therapeutique |
Also Published As
| Publication number | Publication date |
|---|---|
| IE48278B1 (en) | 1984-11-28 |
| DE2913295C2 (OSRAM) | 1988-09-22 |
| GB2019836A (en) | 1979-11-07 |
| BE875246A (fr) | 1979-10-01 |
| FR2423490B1 (OSRAM) | 1982-03-19 |
| CA1117112A (en) | 1982-01-26 |
| US4192944A (en) | 1980-03-11 |
| NL7902444A (nl) | 1979-10-05 |
| IE790950L (en) | 1979-10-03 |
| JPS6256874B2 (OSRAM) | 1987-11-27 |
| SE440652B (sv) | 1985-08-12 |
| IT1116537B (it) | 1986-02-10 |
| ZA791525B (en) | 1980-11-26 |
| DE2913295A1 (de) | 1979-10-18 |
| SE7902915L (sv) | 1979-10-04 |
| CH643256A5 (de) | 1984-05-30 |
| JPS54141797A (en) | 1979-11-05 |
| DK153485B (da) | 1988-07-18 |
| DK130079A (da) | 1979-10-04 |
| IT7948569A0 (it) | 1979-04-02 |
| LU81107A1 (fr) | 1979-11-07 |
| DK153485C (da) | 1988-11-21 |
| GB2019836B (en) | 1982-06-03 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| ST | Notification of lapse |