FR2428630A1 - Derives d'acide 3-amino-2-(5-fluoro- ou 5-methoxy-1h-indol-3-yl)-propanoique, leur procede de production et medicament les contenant - Google Patents

Derives d'acide 3-amino-2-(5-fluoro- ou 5-methoxy-1h-indol-3-yl)-propanoique, leur procede de production et medicament les contenant

Info

Publication number
FR2428630A1
FR2428630A1 FR7915278A FR7915278A FR2428630A1 FR 2428630 A1 FR2428630 A1 FR 2428630A1 FR 7915278 A FR7915278 A FR 7915278A FR 7915278 A FR7915278 A FR 7915278A FR 2428630 A1 FR2428630 A1 FR 2428630A1
Authority
FR
France
Prior art keywords
indol
fluoro
methoxy
amino
production process
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7915278A
Other languages
English (en)
Other versions
FR2428630B1 (fr
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bayer Corp
Original Assignee
Miles Laboratories Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Miles Laboratories Inc filed Critical Miles Laboratories Inc
Publication of FR2428630A1 publication Critical patent/FR2428630A1/fr
Application granted granted Critical
Publication of FR2428630B1 publication Critical patent/FR2428630B1/fr
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/18—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D209/26—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with an acyl radical attached to the ring nitrogen atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/18—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/18—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D209/20—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals substituted additionally by nitrogen atoms, e.g. tryptophane

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Cardiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Indole Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

L'invention a trait au domaine de la chimie pharmaceutique. Elle concerne des composés nouveaux de formule I :
FR7915278A 1978-06-15 1979-06-14 Derives d'acide 3-amino-2-(5-fluoro- ou 5-methoxy-1h-indol-3-yl)-propanoique, leur procede de production et medicament les contenant Granted FR2428630A1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US91573578A 1978-06-15 1978-06-15

Publications (2)

Publication Number Publication Date
FR2428630A1 true FR2428630A1 (fr) 1980-01-11
FR2428630B1 FR2428630B1 (fr) 1983-04-15

Family

ID=25436194

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7915278A Granted FR2428630A1 (fr) 1978-06-15 1979-06-14 Derives d'acide 3-amino-2-(5-fluoro- ou 5-methoxy-1h-indol-3-yl)-propanoique, leur procede de production et medicament les contenant

Country Status (6)

Country Link
JP (1) JPS6040420B2 (fr)
CA (1) CA1098910A (fr)
DE (1) DE2921978A1 (fr)
FR (1) FR2428630A1 (fr)
GB (1) GB2023590B (fr)
IL (1) IL57367A0 (fr)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0514111U (ja) * 1991-08-12 1993-02-23 エステー化学株式会社 作業用腕カバー
JPH0519308U (ja) * 1991-08-23 1993-03-09 由美子 松本 日焼防止ブラウス
WO2015002915A1 (fr) 2013-07-02 2015-01-08 Bristol-Myers Squibb Company Dérivés pyridocarboxamide tricycliques comme inhibiteurs de la voie rock
WO2015002926A1 (fr) 2013-07-02 2015-01-08 Bristol-Myers Squibb Company Dérivés pyrido-carboxamides tricycliques servant d'inhibiteurs de rock

Also Published As

Publication number Publication date
GB2023590A (en) 1980-01-03
DE2921978A1 (de) 1979-12-20
FR2428630B1 (fr) 1983-04-15
CA1098910A (fr) 1981-04-07
JPS6040420B2 (ja) 1985-09-11
IL57367A0 (en) 1979-09-30
DE2921978C2 (fr) 1988-09-01
GB2023590B (en) 1982-11-17
JPS55397A (en) 1980-01-05

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Legal Events

Date Code Title Description
ST Notification of lapse