JPS55397A - 33aminoo22*55fluoroo and 55methoxyy1hh indolee33yl*propane acid derivatives*their manufacture and use - Google Patents

33aminoo22*55fluoroo and 55methoxyy1hh indolee33yl*propane acid derivatives*their manufacture and use

Info

Publication number
JPS55397A
JPS55397A JP7408279A JP7408279A JPS55397A JP S55397 A JPS55397 A JP S55397A JP 7408279 A JP7408279 A JP 7408279A JP 7408279 A JP7408279 A JP 7408279A JP S55397 A JPS55397 A JP S55397A
Authority
JP
Japan
Prior art keywords
55fluoroo
33aminoo22
manufacture
acid derivatives
propane acid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP7408279A
Other languages
Japanese (ja)
Other versions
JPS6040420B2 (en
Inventor
Nooman Shiyutsuto Robaato
Erooru Safudeii Matsukusu
Hongu Enrike
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bayer Corp
Original Assignee
Miles Laboratories Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Miles Laboratories Inc filed Critical Miles Laboratories Inc
Publication of JPS55397A publication Critical patent/JPS55397A/en
Publication of JPS6040420B2 publication Critical patent/JPS6040420B2/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/18—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D209/26—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with an acyl radical attached to the ring nitrogen atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/18—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/18—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D209/20—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals substituted additionally by nitrogen atoms, e.g. tryptophane

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Indole Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
JP54074082A 1978-06-15 1979-06-14 3-Amino-2-(5-fluoro- and 5-methoxy-1H-indol-3-yl)propanoic acid derivatives, their preparation and use Expired JPS6040420B2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US91573578A 1978-06-15 1978-06-15
US915735 2001-07-26

Publications (2)

Publication Number Publication Date
JPS55397A true JPS55397A (en) 1980-01-05
JPS6040420B2 JPS6040420B2 (en) 1985-09-11

Family

ID=25436194

Family Applications (1)

Application Number Title Priority Date Filing Date
JP54074082A Expired JPS6040420B2 (en) 1978-06-15 1979-06-14 3-Amino-2-(5-fluoro- and 5-methoxy-1H-indol-3-yl)propanoic acid derivatives, their preparation and use

Country Status (6)

Country Link
JP (1) JPS6040420B2 (en)
CA (1) CA1098910A (en)
DE (1) DE2921978A1 (en)
FR (1) FR2428630A1 (en)
GB (1) GB2023590B (en)
IL (1) IL57367A0 (en)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0514111U (en) * 1991-08-12 1993-02-23 エステー化学株式会社 Work arm cover
JPH0519308U (en) * 1991-08-23 1993-03-09 由美子 松本 Sun protection blouse
US9663529B2 (en) 2013-07-02 2017-05-30 Bristol-Myers Squibb Company Tricyclic pyrido-carboxamide derivatives as rock inhibitors
ES2633987T3 (en) 2013-07-02 2017-09-26 Bristol-Myers Squibb Company Tricyclic pyrido-carboxamide derivatives as ROCK inhibitors

Also Published As

Publication number Publication date
DE2921978C2 (en) 1988-09-01
FR2428630B1 (en) 1983-04-15
IL57367A0 (en) 1979-09-30
JPS6040420B2 (en) 1985-09-11
GB2023590B (en) 1982-11-17
DE2921978A1 (en) 1979-12-20
FR2428630A1 (en) 1980-01-11
CA1098910A (en) 1981-04-07
GB2023590A (en) 1980-01-03

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