FR2417106A1 - Reactifs en particules utiles dans des determinations immunologiques - Google Patents
Reactifs en particules utiles dans des determinations immunologiquesInfo
- Publication number
- FR2417106A1 FR2417106A1 FR7903485A FR7903485A FR2417106A1 FR 2417106 A1 FR2417106 A1 FR 2417106A1 FR 7903485 A FR7903485 A FR 7903485A FR 7903485 A FR7903485 A FR 7903485A FR 2417106 A1 FR2417106 A1 FR 2417106A1
- Authority
- FR
- France
- Prior art keywords
- reagent
- monomers
- monomer
- matrix
- polymer matrix
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 239000003153 chemical reaction reagent Substances 0.000 title abstract 5
- 230000001900 immune effect Effects 0.000 title 1
- 239000000178 monomer Substances 0.000 abstract 6
- 239000011159 matrix material Substances 0.000 abstract 5
- 239000002245 particle Substances 0.000 abstract 2
- 229920000642 polymer Polymers 0.000 abstract 2
- 239000007787 solid Substances 0.000 abstract 2
- JIHQDMXYYFUGFV-UHFFFAOYSA-N 1,3,5-triazine Chemical compound C1=NC=NC=N1 JIHQDMXYYFUGFV-UHFFFAOYSA-N 0.000 abstract 1
- NLHHRLWOUZZQLW-UHFFFAOYSA-N Acrylonitrile Chemical compound C=CC#N NLHHRLWOUZZQLW-UHFFFAOYSA-N 0.000 abstract 1
- NOWKCMXCCJGMRR-UHFFFAOYSA-N Aziridine Chemical compound C1CN1 NOWKCMXCCJGMRR-UHFFFAOYSA-N 0.000 abstract 1
- GYCMBHHDWRMZGG-UHFFFAOYSA-N Methylacrylonitrile Chemical compound CC(=C)C#N GYCMBHHDWRMZGG-UHFFFAOYSA-N 0.000 abstract 1
- ZMZDMBWJUHKJPS-UHFFFAOYSA-M Thiocyanate anion Chemical compound [S-]C#N ZMZDMBWJUHKJPS-UHFFFAOYSA-M 0.000 abstract 1
- 125000004018 acid anhydride group Chemical group 0.000 abstract 1
- HFBMWMNUJJDEQZ-UHFFFAOYSA-N acryloyl chloride Chemical compound ClC(=O)C=C HFBMWMNUJJDEQZ-UHFFFAOYSA-N 0.000 abstract 1
- 150000001299 aldehydes Chemical class 0.000 abstract 1
- 125000003118 aryl group Chemical group 0.000 abstract 1
- 125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 abstract 1
- SXZHPAWDTKNSMJ-UHFFFAOYSA-N cyanato peroxycyanate Chemical compound N#COOOC#N SXZHPAWDTKNSMJ-UHFFFAOYSA-N 0.000 abstract 1
- 150000002118 epoxides Chemical class 0.000 abstract 1
- ZMZDMBWJUHKJPS-UHFFFAOYSA-N hydrogen thiocyanate Natural products SC#N ZMZDMBWJUHKJPS-UHFFFAOYSA-N 0.000 abstract 1
- 150000003949 imides Chemical class 0.000 abstract 1
- 125000001841 imino group Chemical group [H]N=* 0.000 abstract 1
- 238000003018 immunoassay Methods 0.000 abstract 1
- 239000012948 isocyanate Substances 0.000 abstract 1
- 150000002513 isocyanates Chemical class 0.000 abstract 1
- 150000002540 isothiocyanates Chemical class 0.000 abstract 1
- CTAPFRYPJLPFDF-UHFFFAOYSA-N isoxazole Chemical compound C=1C=NOC=1 CTAPFRYPJLPFDF-UHFFFAOYSA-N 0.000 abstract 1
- VHRYZQNGTZXDNX-UHFFFAOYSA-N methacryloyl chloride Chemical compound CC(=C)C(Cl)=O VHRYZQNGTZXDNX-UHFFFAOYSA-N 0.000 abstract 1
- 239000011236 particulate material Substances 0.000 abstract 1
- 238000006116 polymerization reaction Methods 0.000 abstract 1
- YBBRCQOCSYXUOC-UHFFFAOYSA-N sulfuryl dichloride Chemical compound ClS(Cl)(=O)=O YBBRCQOCSYXUOC-UHFFFAOYSA-N 0.000 abstract 1
- 229920003176 water-insoluble polymer Polymers 0.000 abstract 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
- G01N33/54313—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being characterised by its particulate form
- G01N33/54326—Magnetic particles
- G01N33/5434—Magnetic particles using magnetic particle immunoreagent carriers which constitute new materials per se
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2446/00—Magnetic particle immunoreagent carriers
- G01N2446/20—Magnetic particle immunoreagent carriers the magnetic material being present in the particle core
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2446/00—Magnetic particle immunoreagent carriers
- G01N2446/40—Magnetic particle immunoreagent carriers the magnetic material being dispersed in the monomer composition prior to polymerisation
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2446/00—Magnetic particle immunoreagent carriers
- G01N2446/80—Magnetic particle immunoreagent carriers characterised by the agent used to coat the magnetic particles, e.g. lipids
- G01N2446/86—Magnetic particle immunoreagent carriers characterised by the agent used to coat the magnetic particles, e.g. lipids the coating being pre-functionalised for attaching immunoreagents, e.g. aminodextran
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2446/00—Magnetic particle immunoreagent carriers
- G01N2446/80—Magnetic particle immunoreagent carriers characterised by the agent used to coat the magnetic particles, e.g. lipids
- G01N2446/90—Magnetic particle immunoreagent carriers characterised by the agent used to coat the magnetic particles, e.g. lipids characterised by small molecule linker used to couple immunoreagents to magnetic particles
Landscapes
- Health & Medical Sciences (AREA)
- Immunology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Biomedical Technology (AREA)
- Chemical & Material Sciences (AREA)
- Hematology (AREA)
- Urology & Nephrology (AREA)
- Food Science & Technology (AREA)
- General Physics & Mathematics (AREA)
- Cell Biology (AREA)
- Biotechnology (AREA)
- Medicinal Chemistry (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Microbiology (AREA)
- Pathology (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
- Peptides Or Proteins (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Graft Or Block Polymers (AREA)
- Compositions Of Macromolecular Compounds (AREA)
- Polymerisation Methods In General (AREA)
Abstract
Réactifs en particules pour les déterminations immunologiques. Pour former une matière attirable par l'aimant, on polymérise un monomère en présence de solides attirables par l'aimant de sorte que la matière formée contienne des groupes réactifs libres capables de se coupler directement avec une substance réactive telle qu'une protéine afin de fixer cette substance à la matière; en particulier cette matière sert à préparer des réactifs en particules attirables par l'aimant pour déterminations immunologiques. Applications : détermination d'antigènes, d'anticorps et de médicaments dans les liquides d'origine biologique etc.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB567178 | 1978-02-13 |
Publications (2)
Publication Number | Publication Date |
---|---|
FR2417106A1 true FR2417106A1 (fr) | 1979-09-07 |
FR2417106B1 FR2417106B1 (fr) | 1984-08-10 |
Family
ID=9800467
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
FR7903485A Granted FR2417106A1 (fr) | 1978-02-13 | 1979-02-12 | Reactifs en particules utiles dans des determinations immunologiques |
Country Status (10)
Country | Link |
---|---|
JP (2) | JPS54145211A (fr) |
AU (1) | AU527144B2 (fr) |
BE (1) | BE874091A (fr) |
CA (1) | CA1136400A (fr) |
CH (1) | CH658728A5 (fr) |
DE (1) | DE2905154A1 (fr) |
FR (1) | FR2417106A1 (fr) |
IT (1) | IT1119273B (fr) |
NL (1) | NL7901025A (fr) |
SE (1) | SE7901166L (fr) |
Families Citing this family (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0180384B1 (fr) * | 1984-11-01 | 1991-04-24 | TECHNICON INSTRUMENTS CORPORATION(a Delaware corporation) | Porteur-réactif sensible au magnétisme et procédé de préparation |
JPH073425B2 (ja) * | 1985-01-19 | 1995-01-18 | 東ソー株式会社 | 免疫反応用担体の製造方法 |
JPH07113640B2 (ja) * | 1986-07-07 | 1995-12-06 | 東ソー株式会社 | 蛋白質固定化用担体およびその製法 |
JP2672151B2 (ja) * | 1989-07-14 | 1997-11-05 | 三井東圧化学株式会社 | 磁性体を利用した酵素免疫測定法 |
JPH03109648U (fr) * | 1990-02-27 | 1991-11-11 | ||
DE10235302A1 (de) * | 2002-08-01 | 2004-02-12 | Henkel Kgaa | Verfahren zur Herstellung perl- bzw. kugelförmiger magnetischer Partikel auf Acrylsäuresbasis zur Aufreinigung biologischer Substanzen |
JP4812105B2 (ja) * | 2006-11-10 | 2011-11-09 | ピジョン株式会社 | 食事用エプロン |
EP2173165A4 (fr) * | 2007-07-19 | 2013-03-27 | Chemeq Ltd | Composition de poly-acroléine biocide |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3296234A (en) * | 1964-06-23 | 1967-01-03 | Grace W R & Co | Aqueous process for polymerizing acrylonitrile in the presence of silver nitrate and a hydrocarbon liquid |
JPS5146552B2 (fr) * | 1972-12-04 | 1976-12-09 | ||
FR2313394A1 (fr) * | 1975-06-06 | 1976-12-31 | Nestle Sa | Procede de preparation d'un produit doue d'activite enzymatique |
FR2334106A1 (fr) * | 1975-12-02 | 1977-07-01 | Pasteur Institut | Gel magnetique convenant pour dosages immunoenzymatiques |
GB1575805A (en) * | 1976-03-12 | 1980-10-01 | Technicon Instr | Automatic diagnostic apparatus |
-
1979
- 1979-02-09 AU AU44115/79A patent/AU527144B2/en not_active Ceased
- 1979-02-09 NL NL7901025A patent/NL7901025A/xx not_active Application Discontinuation
- 1979-02-10 DE DE19792905154 patent/DE2905154A1/de active Granted
- 1979-02-12 FR FR7903485A patent/FR2417106A1/fr active Granted
- 1979-02-12 CA CA000321254A patent/CA1136400A/fr not_active Expired
- 1979-02-12 BE BE0/193397A patent/BE874091A/fr not_active IP Right Cessation
- 1979-02-12 IT IT67300/79A patent/IT1119273B/it active
- 1979-02-13 CH CH1367/79A patent/CH658728A5/de not_active IP Right Cessation
- 1979-02-13 JP JP1439579A patent/JPS54145211A/ja active Granted
- 1979-05-07 SE SE7901166A patent/SE7901166L/ not_active Application Discontinuation
-
1987
- 1987-09-09 JP JP62224192A patent/JPS63183909A/ja active Granted
Also Published As
Publication number | Publication date |
---|---|
IT1119273B (it) | 1986-03-10 |
FR2417106B1 (fr) | 1984-08-10 |
JPS6342229B2 (fr) | 1988-08-22 |
SE7901166L (sv) | 1979-08-14 |
DE2905154C2 (fr) | 1989-09-14 |
CA1136400A (fr) | 1982-11-30 |
AU4411579A (en) | 1979-10-25 |
JPS63183909A (ja) | 1988-07-29 |
CH658728A5 (en) | 1986-11-28 |
IT7967300A0 (it) | 1979-02-12 |
JPH0459587B2 (fr) | 1992-09-22 |
BE874091A (fr) | 1979-08-13 |
AU527144B2 (en) | 1983-02-17 |
JPS54145211A (en) | 1979-11-13 |
NL7901025A (nl) | 1979-08-15 |
DE2905154A1 (de) | 1979-08-30 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
EP0054249B2 (fr) | Particules immunologiques et procédé pour leur préparation | |
US4415700A (en) | Hydrophilic latex particles and use thereof | |
US4480042A (en) | Covalently bonded high refractive index particle reagents and their use in light scattering immunoassays | |
US3764477A (en) | Resin bound protein like active agents prepared by reacting a proteinwith a water insoluble polymer of acrylic or methacrylic acid anhydride | |
FR2417106A1 (fr) | Reactifs en particules utiles dans des determinations immunologiques | |
NO971072D0 (no) | Polymerperler, samt fremgangsmåte for fremstilling av disse | |
DE69228019D1 (de) | Verfahren zum Recycling von wasserabsorbierendem feinkörnigem Gut in eine Polymerisationsvorrichtung | |
JPH04339808A (ja) | カルボキシ含有ポリマーから製造された生物活性試薬、分析要素及び使用方法 | |
IE912082A1 (en) | Use of 1-(1-pyrrolidinylcarbonyl) pyridinium salts to attach¹compounds to carboxylated particles and a kit containing¹same | |
EP0038960A2 (fr) | Agent de diagnostic pour tests immunologiques et procédé pour sa préparation | |
IE980447A1 (en) | Succinimide containing polymers and latices prepared from same | |
EP0142810A2 (fr) | Composés polymérisables contenant intégralement des anticorps et leurs utilisations dans le dosage immunologique à base de séparation induite par polymérisation | |
JPH11287802A (ja) | 表面保護剤 | |
CA1301647C (fr) | Latex servant a l'immobilisation d'une substance physiologiquement active, et reactif utilisant ce latex | |
Sarobe et al. | Functionalized monodisperse particles with chloromethyl groups for the covalent coupling of proteins | |
JP2736143B2 (ja) | カルボキシル基含有重合体を含む免疫化学試験用剤 | |
JP2642697B2 (ja) | 固相指示薬の赤血球およびその調製法 | |
GB1265818A (fr) | ||
Suen et al. | Reactive latex studies, 2. Kinetics and retention of enzymatic activity in the covalent protein bonding to a polymer latex | |
JPS5764229A (en) | Self-sensitizig type photosensitive material | |
SE8401437D0 (sv) | Ytmodifierade plastytor och dess tillempningar for immunoassays (ia) | |
JPS5759167A (en) | Production of latex reagent | |
GB2014162A (en) | A particulate reagent, (e.g.) for use in immunoassays | |
JPS5796260A (en) | Immunoactive particle | |
JPH0954092A (ja) | 免疫学的活性物質単量体、重合体および免疫学的活性物質測定試薬 |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
TP | Transmission of property | ||
ST | Notification of lapse |