FR2400903A1 - Vehicules pharmaceutiques liquides, transparents, miscibles a l'eau et compositions se gelifiant a la temperature du corps pour l'apport de produits pharmaceutiques a des membranes muqueuses - Google Patents

Vehicules pharmaceutiques liquides, transparents, miscibles a l'eau et compositions se gelifiant a la temperature du corps pour l'apport de produits pharmaceutiques a des membranes muqueuses

Info

Publication number
FR2400903A1
FR2400903A1 FR7725923A FR7725923A FR2400903A1 FR 2400903 A1 FR2400903 A1 FR 2400903A1 FR 7725923 A FR7725923 A FR 7725923A FR 7725923 A FR7725923 A FR 7725923A FR 2400903 A1 FR2400903 A1 FR 2400903A1
Authority
FR
France
Prior art keywords
liquid
delivery
miscible
water
body temperature
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7725923A
Other languages
English (en)
French (fr)
Other versions
FR2400903B1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
KREZANOSKI JOSEPH
Original Assignee
KREZANOSKI JOSEPH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by KREZANOSKI JOSEPH filed Critical KREZANOSKI JOSEPH
Publication of FR2400903A1 publication Critical patent/FR2400903A1/fr
Application granted granted Critical
Publication of FR2400903B1 publication Critical patent/FR2400903B1/fr
Granted legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/02—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0048—Eye, e.g. artificial tears
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Ophthalmology & Optometry (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Inorganic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
FR7725923A 1976-02-26 1977-08-25 Vehicules pharmaceutiques liquides, transparents, miscibles a l'eau et compositions se gelifiant a la temperature du corps pour l'apport de produits pharmaceutiques a des membranes muqueuses Granted FR2400903A1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US05/661,612 US4100271A (en) 1976-02-26 1976-02-26 Clear, water-miscible, liquid pharmaceutical vehicles and compositions which gel at body temperature for drug delivery to mucous membranes

Publications (2)

Publication Number Publication Date
FR2400903A1 true FR2400903A1 (fr) 1979-03-23
FR2400903B1 FR2400903B1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) 1983-10-28

Family

ID=24654353

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7725923A Granted FR2400903A1 (fr) 1976-02-26 1977-08-25 Vehicules pharmaceutiques liquides, transparents, miscibles a l'eau et compositions se gelifiant a la temperature du corps pour l'apport de produits pharmaceutiques a des membranes muqueuses

Country Status (9)

Country Link
US (1) US4100271A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
JP (1) JPS52125619A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
AU (1) AU515420B2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
CA (1) CA1090252A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
CH (1) CH629385A5 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
DE (1) DE2708152B2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
FR (1) FR2400903A1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
GB (1) GB1571832A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
NL (1) NL7709273A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1986000813A1 (en) * 1984-07-27 1986-02-13 Schering Aktiengesellschaft Pharmaceutical compositions containing gels
EP0202837A1 (en) * 1985-05-17 1986-11-26 Smithkline Beckman Corporation Polyene antibiotic emulsion formulation
ES2063662A1 (es) * 1992-10-13 1995-01-01 Inverni Della Beffa Spa Preparaciones oftalmicas de liberacion extendida.

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US4511554A (en) * 1980-06-02 1985-04-16 Bristol-Myers Company Non-staining antiperspirant stick composition
US4287176A (en) * 1980-10-09 1981-09-01 American Cyanamid Co. Anthelmintic levamisole and tetramisole gel compositions
US4368186A (en) * 1981-05-07 1983-01-11 Syntex (U.S.A.) Inc. Methods and compositions for intravaginal contraception
US4609546A (en) * 1982-06-24 1986-09-02 Japan Chemical Research Co., Ltd. Long-acting composition
DE3474632D1 (en) * 1983-03-01 1988-11-24 Crc Ricerca Chim Pharmaceutical compositions containing the cytidine monophosphate of 5-acetamido-3,5-dideoxy-d-glycero-d-galactononulosaminic acid
US4511563A (en) * 1983-07-15 1985-04-16 Basf Wyandotte Corporation Clear analgesic gels with reduced tackiness
DE3532562A1 (de) * 1985-09-12 1987-03-12 Dolorgiet Gmbh & Co Kg Transdermal resorbierbare, wasserhaltige zubereitungen von arylpropionsaeurederivaten und verfahren zur herstellung derselben
US4931274A (en) * 1986-02-27 1990-06-05 Physiological Research Associates Composition for the effective treatment of scalp diseases that delivers magnesium adsorbed in alumina silicate clays to affected sites
US5080894A (en) * 1986-05-15 1992-01-14 Emory University Method and composition for reducing tissue damage
US5078995A (en) * 1986-05-15 1992-01-07 Emory University Fibrionolytic composition
US5250294A (en) * 1986-05-15 1993-10-05 Emory University Improved perfusion medium for transplantation of organs
US5030448A (en) * 1986-05-15 1991-07-09 Emory University Method of delivering drugs to damaged or diseased tissue
US5028599A (en) * 1986-05-15 1991-07-02 Emory University Method of treating mycardial damage
US5648071A (en) * 1986-05-15 1997-07-15 Emory University Method of treating tumors
US5071649A (en) * 1986-05-15 1991-12-10 Emory University Method of preventing blockage in catheters
US5240701A (en) * 1986-05-15 1993-08-31 Emory University Method of performing angioplasty procedures
US5089260A (en) * 1986-05-15 1992-02-18 Emory University Method of treating ischemic tissue
US4937070A (en) * 1986-05-15 1990-06-26 Emory University Methods and compositions for treatment of pathological hydrophobic interactions in biological fluids
US5017370A (en) * 1986-05-15 1991-05-21 Emory University Improved method of performing angioplasty procedures
US5047236A (en) * 1986-05-15 1991-09-10 Emory University Method of treating stroke
US5039520A (en) * 1986-05-15 1991-08-13 Emory University Plasma extender
US5041288A (en) * 1986-05-15 1991-08-20 Emory University Method of treating tissue damaged by reperfusion injury
US5032394A (en) * 1986-05-15 1991-07-16 Emory University Method of treating burns
US5182106A (en) * 1986-05-15 1993-01-26 Emory University Method for treating hypothermia
US4997644A (en) * 1986-05-15 1991-03-05 Emory University Method of treating adult respiratory distress syndrome
US5811088A (en) * 1987-02-20 1998-09-22 Emory University Antiinfective compounds and methods of use
US5674911A (en) * 1987-02-20 1997-10-07 Cytrx Corporation Antiinfective polyoxypropylene/polyoxyethylene copolymers and methods of use
GB2203039B (en) * 1987-03-02 1990-10-24 American Cyanamid Co Stable ophthalmic preparations containing acetazolamide
US5457093A (en) * 1987-09-18 1995-10-10 Ethicon, Inc. Gel formulations containing growth factors
NZ226171A (en) * 1987-09-18 1990-06-26 Ethicon Inc Gel formulation containing polypeptide growth factor
US5981485A (en) * 1997-07-14 1999-11-09 Genentech, Inc. Human growth hormone aqueous formulation
US5681576A (en) * 1988-11-16 1997-10-28 Mdv Technologies, Inc. Method and composition for post surgical adhesion reduction
US5135751A (en) * 1988-11-16 1992-08-04 Mediventures Incorporated Composition for reducing postsurgical adhesions
US6436425B1 (en) 1988-11-16 2002-08-20 Mdv Technologies, Inc. Method and non-gelling composition for inhibiting post-surgical adhesions
CA2011423A1 (en) * 1989-03-07 1990-09-07 Peter M. Taylor Pharmaceutical compositions useful as drug delivery vehicles and/or as wound dressings
US5593683A (en) * 1990-05-01 1997-01-14 Mdv Technologies, Inc. Method of making thermoreversible polyoxyalkylene gels
CA2040460C (en) * 1990-05-01 1997-06-10 Tacey X. Viegas Drug delivery with thermoreversible gels
GB2248842A (en) * 1990-10-16 1992-04-22 American Cyanamid Co Film-forming polymer compositions
US5847023A (en) * 1990-10-26 1998-12-08 Mdv Technologies, Inc. Thermal irreversible gel corneal contact lens formed in situ
USRE38558E1 (en) 1991-03-19 2004-07-20 Cytrx Corporation Polyoxypropylene/polyoxyethylene copolymers with improved biological activity
US6933286B2 (en) 1991-03-19 2005-08-23 R. Martin Emanuele Therapeutic delivery compositions and methods of use thereof
US5696298A (en) * 1991-03-19 1997-12-09 Cytrx Corporation Polyoxypropylene/polyoxyethylene copolymers with improved biological activity
WO1992016484A1 (en) * 1991-03-19 1992-10-01 Cytrx Corporation Polyoxypropylene/polyoxyethylene copolymers with improved biological activity
US20020123476A1 (en) * 1991-03-19 2002-09-05 Emanuele R. Martin Therapeutic delivery compositions and methods of use thereof
US7202225B1 (en) 1993-10-15 2007-04-10 Emanuele R Martin Therapeutic delivery compositions and methods of use thereof
US5595732A (en) * 1991-03-25 1997-01-21 Hoffmann-La Roche Inc. Polyethylene-protein conjugates
US5622649A (en) * 1991-06-27 1997-04-22 Emory University Multiple emulsions and methods of preparation
US5318780A (en) * 1991-10-30 1994-06-07 Mediventures Inc. Medical uses of in situ formed gels
US5470568A (en) * 1992-02-13 1995-11-28 Arch Development Corporation Methods and compositions of a polymer (poloxamer) for cell repair
US5605687A (en) * 1992-05-15 1997-02-25 Arch Development Corporation Methods and compositions of a polymer (poloxamer) for repair of electrical injury
JP2683783B2 (ja) * 1992-07-10 1997-12-03 雪印乳業株式会社 シェーグレン症候群治療剤
US5382657A (en) * 1992-08-26 1995-01-17 Hoffmann-La Roche Inc. Peg-interferon conjugates
US5292525A (en) * 1992-10-14 1994-03-08 Merck & Co., Inc. Method and composition for removing an alginate from a cutaneous substrate
ES2141775T3 (es) * 1993-04-16 2000-04-01 Wakamoto Pharma Co Ltd Composicion medicinal a base de agua termicamente gelificante reversible.
AU1119895A (en) * 1993-11-30 1995-06-19 Zenichi Ogita External preparation
US5658560A (en) * 1994-01-18 1997-08-19 Serikov; Vladimir B. Method of treating endotoxemia by administering tyloxapol
AU692852B2 (en) 1994-03-04 1998-06-18 University Of Washington Block and graft copolymers and methods relating thereto
EP0782850A4 (en) * 1994-10-13 1998-03-04 Wakamoto Pharma Co Ltd LYOPHILIZED PREPARATION FOR PRODUCING A REVERSIBLE THERMOGELING MEDICINAL WATER-BASED
WO1997021441A1 (en) * 1995-12-11 1997-06-19 Mdv Technologies, Inc. Ophthalmic composition comprising polyoxyethylene-polyoxypropylene polymers
US5861174A (en) * 1996-07-12 1999-01-19 University Technology Corporation Temperature sensitive gel for sustained delivery of protein drugs
DK1107791T3 (da) 1998-09-04 2007-09-03 Scios Inc Hydrogelpræparater til controlled release-administration af vækstfaktorer
US6312667B1 (en) * 1998-11-12 2001-11-06 3M Innovative Properties Company Methods of etching hard tissue in the oral environment
US6669927B2 (en) 1998-11-12 2003-12-30 3M Innovative Properties Company Dental compositions
US6312666B1 (en) * 1998-11-12 2001-11-06 3M Innovative Properties Company Methods of whitening teeth
CA2383570C (en) 1999-09-11 2008-08-12 The Procter & Gamble Company Pourable liquid vehicles
US7776803B2 (en) * 2001-06-05 2010-08-17 Steven B Leeb Working materials with smart cutting fluids
US7060663B1 (en) 2001-06-05 2006-06-13 Steven B Leeb Smart cutting fluids
US7138133B2 (en) * 2001-10-10 2006-11-21 The Procter & Gamble Company Orally administered liquid compositions
US6620405B2 (en) 2001-11-01 2003-09-16 3M Innovative Properties Company Delivery of hydrogel compositions as a fine mist
AU2008297931A1 (en) 2007-09-11 2009-03-19 Mondobiotech Laboratories Ag Use of RGDSPASSKP and optionally angiotensin II as therapeutic agents in the treatment of Eg S. pneumoniae infections
US20100197600A1 (en) 2007-09-11 2010-08-05 Dorian Bevec Use of the peptide his-ser-leu-gly-lys-trp-leu-gly-his-pro-asp-lys-phe alone or in combination with the peptide pro-gly-thr-cys-glu-ile-cys-ala-tyr-ala-ala-cys-thr-gly-cys-oh as a therapeutic agent
AU2008306272A1 (en) 2007-09-11 2009-04-09 Mondobiotech Laboratories Ag U e of urocortin and corticotropin-releasing fact r as therapeutic agents
WO2009033766A2 (en) 2007-09-11 2009-03-19 Mondobiotech Laboratories Ag Use of a peptide as a therapeutic agent
CA2698980A1 (en) 2007-09-11 2009-03-19 Mondobiotech Laboratories Ag Use of a peptide as a therapeutic agent
WO2009033758A2 (en) 2007-09-11 2009-03-19 Mondobiotech Laboratories Ag Use of the peptide phpfhffvyk as therapeutic agent
WO2009033748A2 (en) 2007-09-11 2009-03-19 Mondobiotech Laboratories Ag Use of osteostatin, alone or in combination with thymopentin, as a therapeutic agent
KR20100057054A (ko) 2007-09-11 2010-05-28 몬도바이오테크 래보래토리즈 아게 치료제로서의 터프친의 용도
WO2009040020A1 (en) 2007-09-11 2009-04-02 Mondobiotech Laboratories Ag Amylin as a therapeutic agent
AU2008297551A1 (en) 2007-09-11 2009-03-19 Mondobiotech Laboratories Ag Use of a defensin peptide as a therapeutic agent
WO2011113507A2 (en) 2010-03-15 2011-09-22 Ulrich Dietz Use of nitrocarboxylic acids for the treatment, diagnosis and prophylaxis of aggressive healing patterns
EP3453722A1 (en) 2017-09-06 2019-03-13 Julius-Maximilians-Universität Würzburg Pharmaceuticals and devices for the covalent immobilization to the extracellular matrix by transglutaminase
US20210171598A1 (en) 2017-12-01 2021-06-10 University Of Copenhagen Peptide hormone with one or more o-glycans
EP3569614A1 (en) 2018-05-18 2019-11-20 Julius-Maximilians-Universität Würzburg Compounds and methods for the immobilization of myostatin-inhibitors on the extracellular matrix by transglutaminase

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US3767788A (en) * 1970-06-08 1973-10-23 Burton Parsons Chemicals Inc Ophthalmic solution
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Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1986000813A1 (en) * 1984-07-27 1986-02-13 Schering Aktiengesellschaft Pharmaceutical compositions containing gels
EP0202837A1 (en) * 1985-05-17 1986-11-26 Smithkline Beckman Corporation Polyene antibiotic emulsion formulation
ES2063662A1 (es) * 1992-10-13 1995-01-01 Inverni Della Beffa Spa Preparaciones oftalmicas de liberacion extendida.

Also Published As

Publication number Publication date
CA1090252A (en) 1980-11-25
CH629385A5 (de) 1982-04-30
DE2708152A1 (de) 1977-09-08
US4100271A (en) 1978-07-11
AU515420B2 (en) 1981-04-02
DE2708152B2 (de) 1981-02-19
JPS52125619A (en) 1977-10-21
JPS5748049B2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) 1982-10-14
GB1571832A (en) 1980-07-23
FR2400903B1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) 1983-10-28
AU2794977A (en) 1979-02-22
NL7709273A (nl) 1979-02-27

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