FR2397404A1 - Nouveaux 3-indolyl-tertiobutylaminopropanols et medicament les contenant - Google Patents

Nouveaux 3-indolyl-tertiobutylaminopropanols et medicament les contenant

Info

Publication number
FR2397404A1
FR2397404A1 FR7820851A FR7820851A FR2397404A1 FR 2397404 A1 FR2397404 A1 FR 2397404A1 FR 7820851 A FR7820851 A FR 7820851A FR 7820851 A FR7820851 A FR 7820851A FR 2397404 A1 FR2397404 A1 FR 2397404A1
Authority
FR
France
Prior art keywords
indolyl
tertiobutylaminopropanols
new
compounds
products containing
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7820851A
Other languages
English (en)
French (fr)
Other versions
FR2397404B1 (it
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bristol Myers Co
Original Assignee
Bristol Myers Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bristol Myers Co filed Critical Bristol Myers Co
Publication of FR2397404A1 publication Critical patent/FR2397404A1/fr
Application granted granted Critical
Publication of FR2397404B1 publication Critical patent/FR2397404B1/fr
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/14—Radicals substituted by nitrogen atoms, not forming part of a nitro radical
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/06—Antiarrhythmics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hospice & Palliative Care (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Indole Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
FR7820851A 1977-07-13 1978-07-12 Nouveaux 3-indolyl-tertiobutylaminopropanols et medicament les contenant Granted FR2397404A1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US81513877A 1977-07-13 1977-07-13

Publications (2)

Publication Number Publication Date
FR2397404A1 true FR2397404A1 (fr) 1979-02-09
FR2397404B1 FR2397404B1 (it) 1982-06-11

Family

ID=25216976

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7820851A Granted FR2397404A1 (fr) 1977-07-13 1978-07-12 Nouveaux 3-indolyl-tertiobutylaminopropanols et medicament les contenant

Country Status (30)

Country Link
JP (1) JPS5419972A (it)
AR (1) AR225274A1 (it)
AT (1) AT364821B (it)
AU (1) AU525064B2 (it)
BE (1) BE868943A (it)
CA (1) CA1116598A (it)
CH (1) CH642066A5 (it)
CY (1) CY1274A (it)
DE (1) DE2830884A1 (it)
DK (1) DK156568C (it)
ES (1) ES471674A1 (it)
FI (1) FI69835C (it)
FR (1) FR2397404A1 (it)
GB (1) GB2001633B (it)
GR (1) GR74488B (it)
HK (1) HK1385A (it)
HU (1) HU178992B (it)
IE (1) IE47122B1 (it)
IL (1) IL55115A (it)
IT (1) IT1105091B (it)
KE (1) KE3485A (it)
LU (1) LU79966A1 (it)
MY (1) MY8500946A (it)
NL (1) NL189946C (it)
NO (1) NO149311C (it)
NZ (1) NZ187763A (it)
SE (1) SE429339B (it)
SG (1) SG82584G (it)
YU (1) YU40528B (it)
ZA (1) ZA783744B (it)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2505337A1 (fr) * 1981-05-07 1982-11-12 Bristol Myers Co Nouveaux thienyl- et benzothienyl-tert-butylaminophenoxypropanols utiles comme medicaments b-bloquants selectifs

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2463765A1 (fr) * 1979-08-17 1981-02-27 Clin Midy Nouveaux derives de l'indole actifs sur le systeme cardiovasculaire
DE3119796A1 (de) * 1981-05-19 1982-12-23 Hoechst Ag, 6000 Frankfurt Substituierte tryptaminderivate von thienyloxpropanolaminen, verfahren zu ihrer herstellung, pharmazeutische praeparate auf basis dieser verbindungen sowie ihre verwendung
FR2523964B1 (fr) * 1982-03-23 1985-09-27 Sanofi Sa Nouveaux derives de la tryptamine actifs notamment sur le systeme cardiovasculaire et procede pour leur preparation
NZ208337A (en) * 1983-06-10 1988-10-28 Bristol Myers Co 2-(2-hydroxy-3-((2-(ar-hydroxy-1h-aminopropoxy-yl)ethyl benzonitriles and pharmaceutical compositions
FR2601008B1 (fr) * 1986-07-03 1990-03-30 Sanofi Sa Procede de synthese stereospecifique de derives de l'indole
JP2004513164A (ja) 2000-11-10 2004-04-30 イーライ・リリー・アンド・カンパニー ３−置換オキシインドールβ３アゴニスト
EP1444224B1 (en) 2001-08-14 2006-05-03 Eli Lilly And Company 3-substituted oxindole beta-3 agonists
ATE340794T1 (de) * 2001-08-14 2006-10-15 Lilly Co Eli Indol derivate als beta-3-adrenerge agonisten zur behandlung von typ 2 diabetes
DE60225174T2 (de) 2001-11-20 2009-02-12 Eli Lilly And Co., Indianapolis Beta-3 adrenergische agonisten
US7205407B2 (en) 2001-11-20 2007-04-17 Eli Lilly And Company 3-Substituted oxindole β3 agonists
EP1467733A1 (en) 2002-01-11 2004-10-20 Eli Lilly And Company 2-oxo-benzimidazolyl substituted ethanolamine derivatives and their use as beta3 agonists
CA2960254A1 (en) 2008-08-01 2010-02-04 Arca Biopharma, Inc. Methods and compositions involving (s)-bucindolol

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3371098A (en) * 1966-11-29 1968-02-27 Philips Corp 5- and 6-methoxy-3-(phenoxyethyl-aminoethyl)-indoles
FR1532210A (fr) * 1963-06-21 1968-07-12 Ici Ltd Composés hétérocycliques et leur procédé de préparation

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH495983A (de) * 1968-02-09 1970-09-15 Sandoz Ag Verfahren zur Herstellung von linksdrehendem 4-(2-Hydroxy-3-isopropylaminopropoxy)indol
US3946009A (en) * 1972-05-05 1976-03-23 Merck Sharp & Dohme (I.A.) Corporation 2-(3-Substituted amino-2-hydroxypropoxy)-3-substituted pyrazines

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR1532210A (fr) * 1963-06-21 1968-07-12 Ici Ltd Composés hétérocycliques et leur procédé de préparation
US3371098A (en) * 1966-11-29 1968-02-27 Philips Corp 5- and 6-methoxy-3-(phenoxyethyl-aminoethyl)-indoles

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2505337A1 (fr) * 1981-05-07 1982-11-12 Bristol Myers Co Nouveaux thienyl- et benzothienyl-tert-butylaminophenoxypropanols utiles comme medicaments b-bloquants selectifs

Also Published As

Publication number Publication date
IT1105091B (it) 1985-10-28
HK1385A (en) 1985-01-11
ATA508978A (de) 1981-04-15
NO149311C (no) 1984-03-28
FI69835B (fi) 1985-12-31
SE7807700L (sv) 1979-01-14
IT7850228A0 (it) 1978-07-10
GB2001633A (en) 1979-02-07
NL189946B (nl) 1993-04-16
JPS5419972A (en) 1979-02-15
DE2830884A1 (de) 1979-02-01
FI782205A (fi) 1979-01-14
CA1116598A (en) 1982-01-19
JPS6340784B2 (it) 1988-08-12
ZA783744B (en) 1979-07-25
CY1274A (en) 1985-03-08
IE781400L (en) 1979-01-13
IL55115A0 (en) 1978-09-29
FI69835C (fi) 1986-05-26
HU178992B (en) 1982-07-28
GR74488B (it) 1984-06-28
DK156568C (da) 1990-02-05
ES471674A1 (es) 1979-10-01
NZ187763A (en) 1984-07-31
SG82584G (en) 1985-09-13
DE2830884C2 (it) 1990-01-11
AU3770478A (en) 1980-01-10
FR2397404B1 (it) 1982-06-11
GB2001633B (en) 1982-03-24
AT364821B (de) 1981-11-25
AR225274A1 (es) 1982-03-15
CH642066A5 (de) 1984-03-30
DK313878A (da) 1979-01-14
NL7807564A (nl) 1979-01-16
NL189946C (nl) 1993-09-16
IL55115A (en) 1981-09-13
YU161178A (en) 1983-02-28
DK156568B (da) 1989-09-11
BE868943A (fr) 1979-01-12
SE429339B (sv) 1983-08-29
LU79966A1 (fr) 1979-04-09
MY8500946A (en) 1985-12-31
IE47122B1 (en) 1983-12-28
YU40528B (en) 1986-02-28
NO782407L (no) 1979-01-16
NO149311B (no) 1983-12-19
AU525064B2 (en) 1982-10-21
KE3485A (en) 1985-01-25

Similar Documents

Publication Publication Date Title
FR2397404A1 (fr) Nouveaux 3-indolyl-tertiobutylaminopropanols et medicament les contenant
NL190757C (nl) 4-(3-Chloorfenyl)-1-piperazinylpropyl gesubstitueerde-1,2,4-triazool-3-on verbindingen met antidepressieve werking en farmaceutische preparaten daarvan.
FR2639636B1 (fr) Nouveaux composes heterocycliques a activite anticonvulsivante, procede de preparation et compositions therapeutiques les contenant
IT7928417A0 (it) Composizioni farmaceutiche con esaltazione dell'attivita'terapeutica di cortisonici.
ATE77077T1 (de) Metoprololsuccinat und dieses enthaltende pharmazeutische zusammensetzung.
IT7928464A0 (it) Composizione farmaceutica avente attivita' antitumorale.
NL990031I2 (nl) Farmaceutisch preparen die N-gesubstitueerde 3-hydroxypyrid-2-on of 4-onderrivaten bevatten.
IT1190824B (it) Composizione farmaceutica contenente 24,25-diidrossicolecalciferolo come ingrediente attivo
DE3583765D1 (de) Hydantoinderivate und diese enthaltende pharmazeutische zusammensetzungen.
FR2591481B1 (fr) Compositions pharmaceutiques douees d'activites vasodilatatrice et anti-anoxique comprenant une coenzyme ubiquinone et un vasodilatateur.
FR2379549A1 (fr) 4''-deoxy-4''-(amino substitue)-oleandomycines et medicament les contenant
FR2398067A1 (fr) Nouvelles 4-pyrones substituees en positions 2, 3 et 6 et medicament les contenant
OA09137A (fr) Nouveaux dérivés de la benzoxazolinone, leurs procédés de préparation et les compositions pharmaceutiques qui les contiennent.
DE3576505D1 (de) 3,4-dihydrobenzopyranverbindungen und diese enthaltende pharmazeutische zusammenstellungen.
FR2599039B1 (fr) Nouvelle substance immuno-suppressive, sa preparation par culture de streptomyces sp. (cbs 162.86) et les compositions pharmaceutiques qui la contiennent
OA07641A (fr) Composés de la benzoylurée, et compositions pesticides et pharmaceutiques les contenant.
IT8026233A0 (it) Derivato della n-acetil-cisteina ad attivita' terapeutica, procedimento per la sua preparazione e relative composizioni farmaceutiche.
IT8423896A0 (it) Diacilderivati della glicerilfosforilcolina ad attivita' terapeutica, procedimento per laloro preparazione e relative composizioni farmaceutiche.
ES2059633T3 (es) 2-terc.-butil-4-cloro-5-(4-terc.-butilbenciltio)-3(2h)-piridazinona para la lucha contra los moluscos.
FR2399840A1 (fr) Application de la 2-cyano-aziridine et de ses derives a l'immunostimulation
FR2369245A1 (fr) Composes tricycliques a activite biologique et compositions pharmaceutiques les renfermant
FR2394539A1 (fr) Nouveaux derives substitues en position 15 d'o-pentanorprostaglandine et leur utilisation comme medicament
OA07444A (fr) Sandale pour femmes, facile et rapide à assembler.
FR2397410A1 (fr) Nouveaux analogues de prostacycline et medicament les contenant
IT8026232A0 (it) Composizioni farmaceutiche. derivato dell'alfa-mercapto propionilglicina ad attivita'terapeutica, procedimento per lasua preparazione e relative