JPS5419972A - 33indolylltertiary butylaminopropanols - Google Patents

33indolylltertiary butylaminopropanols

Info

Publication number
JPS5419972A
JPS5419972A JP8461378A JP8461378A JPS5419972A JP S5419972 A JPS5419972 A JP S5419972A JP 8461378 A JP8461378 A JP 8461378A JP 8461378 A JP8461378 A JP 8461378A JP S5419972 A JPS5419972 A JP S5419972A
Authority
JP
Japan
Prior art keywords
butylaminopropanols
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP8461378A
Other languages
English (en)
Japanese (ja)
Other versions
JPS6340784B2 (it
Inventor
Ii Kureigubaamu Uiriamu
Tei Koomaa Uiriamu
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bristol Myers Co
Original Assignee
Bristol Myers Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bristol Myers Co filed Critical Bristol Myers Co
Publication of JPS5419972A publication Critical patent/JPS5419972A/ja
Publication of JPS6340784B2 publication Critical patent/JPS6340784B2/ja
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/14—Radicals substituted by nitrogen atoms, not forming part of a nitro radical
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/06—Antiarrhythmics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hospice & Palliative Care (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Indole Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
JP8461378A 1977-07-13 1978-07-13 33indolylltertiary butylaminopropanols Granted JPS5419972A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US81513877A 1977-07-13 1977-07-13

Publications (2)

Publication Number Publication Date
JPS5419972A true JPS5419972A (en) 1979-02-15
JPS6340784B2 JPS6340784B2 (it) 1988-08-12

Family

ID=25216976

Family Applications (1)

Application Number Title Priority Date Filing Date
JP8461378A Granted JPS5419972A (en) 1977-07-13 1978-07-13 33indolylltertiary butylaminopropanols

Country Status (30)

Country Link
JP (1) JPS5419972A (it)
AR (1) AR225274A1 (it)
AT (1) AT364821B (it)
AU (1) AU525064B2 (it)
BE (1) BE868943A (it)
CA (1) CA1116598A (it)
CH (1) CH642066A5 (it)
CY (1) CY1274A (it)
DE (1) DE2830884A1 (it)
DK (1) DK156568C (it)
ES (1) ES471674A1 (it)
FI (1) FI69835C (it)
FR (1) FR2397404A1 (it)
GB (1) GB2001633B (it)
GR (1) GR74488B (it)
HK (1) HK1385A (it)
HU (1) HU178992B (it)
IE (1) IE47122B1 (it)
IL (1) IL55115A (it)
IT (1) IT1105091B (it)
KE (1) KE3485A (it)
LU (1) LU79966A1 (it)
MY (1) MY8500946A (it)
NL (1) NL189946C (it)
NO (1) NO149311C (it)
NZ (1) NZ187763A (it)
SE (1) SE429339B (it)
SG (1) SG82584G (it)
YU (1) YU40528B (it)
ZA (1) ZA783744B (it)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2463765A1 (fr) * 1979-08-17 1981-02-27 Clin Midy Nouveaux derives de l'indole actifs sur le systeme cardiovasculaire
US4321398A (en) * 1981-05-07 1982-03-23 Mead Johnson & Company Thienyl and benzothienyl-tertiary butylaminophenoxypropanols
DE3119796A1 (de) * 1981-05-19 1982-12-23 Hoechst Ag, 6000 Frankfurt Substituierte tryptaminderivate von thienyloxpropanolaminen, verfahren zu ihrer herstellung, pharmazeutische praeparate auf basis dieser verbindungen sowie ihre verwendung
FR2523964B1 (fr) * 1982-03-23 1985-09-27 Sanofi Sa Nouveaux derives de la tryptamine actifs notamment sur le systeme cardiovasculaire et procede pour leur preparation
NZ208337A (en) * 1983-06-10 1988-10-28 Bristol Myers Co 2-(2-hydroxy-3-((2-(ar-hydroxy-1h-aminopropoxy-yl)ethyl benzonitriles and pharmaceutical compositions
FR2601008B1 (fr) * 1986-07-03 1990-03-30 Sanofi Sa Procede de synthese stereospecifique de derives de l'indole
JP2004513164A (ja) 2000-11-10 2004-04-30 イーライ・リリー・アンド・カンパニー ３−置換オキシインドールβ３アゴニスト
EP1444224B1 (en) 2001-08-14 2006-05-03 Eli Lilly And Company 3-substituted oxindole beta-3 agonists
ATE340794T1 (de) * 2001-08-14 2006-10-15 Lilly Co Eli Indol derivate als beta-3-adrenerge agonisten zur behandlung von typ 2 diabetes
DE60225174T2 (de) 2001-11-20 2009-02-12 Eli Lilly And Co., Indianapolis Beta-3 adrenergische agonisten
US7205407B2 (en) 2001-11-20 2007-04-17 Eli Lilly And Company 3-Substituted oxindole β3 agonists
EP1467733A1 (en) 2002-01-11 2004-10-20 Eli Lilly And Company 2-oxo-benzimidazolyl substituted ethanolamine derivatives and their use as beta3 agonists
CA2960254A1 (en) 2008-08-01 2010-02-04 Arca Biopharma, Inc. Methods and compositions involving (s)-bucindolol

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR1532210A (fr) * 1963-06-21 1968-07-12 Ici Ltd Composés hétérocycliques et leur procédé de préparation
CH495983A (de) * 1968-02-09 1970-09-15 Sandoz Ag Verfahren zur Herstellung von linksdrehendem 4-(2-Hydroxy-3-isopropylaminopropoxy)indol
US3371098A (en) * 1966-11-29 1968-02-27 Philips Corp 5- and 6-methoxy-3-(phenoxyethyl-aminoethyl)-indoles
US3946009A (en) * 1972-05-05 1976-03-23 Merck Sharp & Dohme (I.A.) Corporation 2-(3-Substituted amino-2-hydroxypropoxy)-3-substituted pyrazines

Also Published As

Publication number Publication date
IT1105091B (it) 1985-10-28
HK1385A (en) 1985-01-11
ATA508978A (de) 1981-04-15
NO149311C (no) 1984-03-28
FI69835B (fi) 1985-12-31
SE7807700L (sv) 1979-01-14
FR2397404A1 (fr) 1979-02-09
IT7850228A0 (it) 1978-07-10
GB2001633A (en) 1979-02-07
NL189946B (nl) 1993-04-16
DE2830884A1 (de) 1979-02-01
FI782205A (fi) 1979-01-14
CA1116598A (en) 1982-01-19
JPS6340784B2 (it) 1988-08-12
ZA783744B (en) 1979-07-25
CY1274A (en) 1985-03-08
IE781400L (en) 1979-01-13
IL55115A0 (en) 1978-09-29
FI69835C (fi) 1986-05-26
HU178992B (en) 1982-07-28
GR74488B (it) 1984-06-28
DK156568C (da) 1990-02-05
ES471674A1 (es) 1979-10-01
NZ187763A (en) 1984-07-31
SG82584G (en) 1985-09-13
DE2830884C2 (it) 1990-01-11
AU3770478A (en) 1980-01-10
FR2397404B1 (it) 1982-06-11
GB2001633B (en) 1982-03-24
AT364821B (de) 1981-11-25
AR225274A1 (es) 1982-03-15
CH642066A5 (de) 1984-03-30
DK313878A (da) 1979-01-14
NL7807564A (nl) 1979-01-16
NL189946C (nl) 1993-09-16
IL55115A (en) 1981-09-13
YU161178A (en) 1983-02-28
DK156568B (da) 1989-09-11
BE868943A (fr) 1979-01-12
SE429339B (sv) 1983-08-29
LU79966A1 (fr) 1979-04-09
MY8500946A (en) 1985-12-31
IE47122B1 (en) 1983-12-28
YU40528B (en) 1986-02-28
NO782407L (no) 1979-01-16
NO149311B (no) 1983-12-19
AU525064B2 (en) 1982-10-21
KE3485A (en) 1985-01-25

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