NL990031I2 - Farmaceutisch preparen die N-gesubstitueerde 3-hydroxypyrid-2-on of 4-onderrivaten bevatten. - Google Patents

Farmaceutisch preparen die N-gesubstitueerde 3-hydroxypyrid-2-on of 4-onderrivaten bevatten.

Info

Publication number
NL990031I2
NL990031I2 NL990031C NL990031C NL990031I2 NL 990031 I2 NL990031 I2 NL 990031I2 NL 990031 C NL990031 C NL 990031C NL 990031 C NL990031 C NL 990031C NL 990031 I2 NL990031 I2 NL 990031I2
Authority
NL
Netherlands
Prior art keywords
hydroxypyrid
derivatives
substituted
sub
pharmaceutical preparations
Prior art date
Application number
NL990031C
Other languages
English (en)
Other versions
NL990031I1 (nl
Original Assignee
Btg Int Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Btg Int Ltd filed Critical Btg Int Ltd
Publication of NL990031I1 publication Critical patent/NL990031I1/nl
Publication of NL990031I2 publication Critical patent/NL990031I2/nl

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/62—Oxygen or sulfur atoms
    • C07D213/69—Two or more oxygen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P39/00—General protective or antinoxious agents
    • A61P39/02—Antidotes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/06—Antianaemics

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Toxicology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyridine Compounds (AREA)
  • Pyrane Compounds (AREA)
NL990031C 1982-03-24 1999-10-06 Farmaceutisch preparen die N-gesubstitueerde 3-hydroxypyrid-2-on of 4-onderrivaten bevatten. NL990031I2 (nl)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB8208608 1982-03-24

Publications (2)

Publication Number Publication Date
NL990031I1 NL990031I1 (nl) 1999-12-01
NL990031I2 true NL990031I2 (nl) 2000-04-03

Family

ID=10529232

Family Applications (1)

Application Number Title Priority Date Filing Date
NL990031C NL990031I2 (nl) 1982-03-24 1999-10-06 Farmaceutisch preparen die N-gesubstitueerde 3-hydroxypyrid-2-on of 4-onderrivaten bevatten.

Country Status (8)

Country Link
US (1) US4840958A (nl)
EP (1) EP0093498B1 (nl)
JP (3) JPS58174319A (nl)
CY (1) CY1502A (nl)
DE (2) DE3367849D1 (nl)
GR (1) GR78491B (nl)
HK (1) HK6190A (nl)
NL (1) NL990031I2 (nl)

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8308055D0 (en) * 1983-03-24 1983-05-05 Hider R C Pharmaceutical compositions
EP0305646B1 (en) * 1983-03-24 1996-11-13 Btg International Limited 3-Hydroxypyrid-4-ones and pharmaceutical compositions
GB8308054D0 (en) * 1983-03-24 1983-05-05 Hider R C Pharmaceutical compositions
USRE34313E (en) * 1983-09-23 1993-07-13 National Research Development Corporation Pharmaceutical compositions
GB8325494D0 (en) * 1983-09-23 1983-10-26 Hider R C Pharmaceutical compositions
US4912118A (en) * 1983-09-23 1990-03-27 National Research Development Corporation Pharmaceutical compositions
WO1989009211A1 (en) * 1988-03-31 1989-10-05 The Royal Free Hospital School Of Medicine Process for producing pyrid-4-ones
GB8910521D0 (en) * 1989-05-08 1989-06-21 Nat Res Dev The stabilization of organic compounds
US5298525A (en) * 1992-11-23 1994-03-29 University Technologies International, Inc. Diabetes prevention and treatment
US6046219A (en) * 1995-01-20 2000-04-04 Cornell Research Foundation, Inc. Method for the treatment of conditions mediated by collagen formation together with cell proliferation by application of inhibitors of protein hydroxylation
US5849587A (en) * 1995-06-09 1998-12-15 Cornell Research Foundation, Inc. Method of inhibiting viral replication in eukaryotic cells and of inducing apoptosis of virally-infected cells
WO1996041627A2 (en) 1995-06-10 1996-12-27 Vitra Pharmaceuticals Ltd Iron compounds, compositions, methods of making the same and uses thereof
US6004986A (en) * 1997-05-08 1999-12-21 The University Of Virginia Patent Foundation Method for treating cerebral vasospasm and cerebral ischemia using iron chelators and pharmaceutical compositions therefor
US6767741B1 (en) * 1999-08-27 2004-07-27 Invitrogen Corporation Metal binding compounds and their use in cell culture medium compositions
IL135884A (en) * 2000-04-30 2005-08-31 Yissum Res Dev Co Method for measuring non-transferrin bound iron
ES2236300T3 (es) * 2000-09-19 2005-07-16 Vitra Pharmaceuticals Ltd. Composiciones de hierro.
US6426418B1 (en) 2001-11-02 2002-07-30 Apotex, Inc. Processes for the manufacturing of 3-hydroxy-N,1,6-trialkyl-4-oxo-1,4-dihydropyridine-2-carboxamide
GB0211500D0 (en) 2002-05-18 2002-06-26 Vitra Pharmaceuticals Ltd Method of forming iron hydroxypyrone compounds
EP1578999B1 (en) 2002-10-30 2013-01-16 Yissum Research Development Company of the Hebrew University of Jerusalem Ltd. Method for measuring non-transferrin bound iron
CA2505476C (en) * 2002-11-07 2015-05-26 Technion Research And Development Foundation Ltd. Neuroprotective iron chelators and pharmaceutical compositions comprising them
CA2488034C (en) * 2004-11-19 2009-10-06 Apotex Inc. Process for the manufacture of 3-hydroxy-n-alkyl-1-cycloalkyl-6-alkyl-4-oxo-1,4-dihydropyridine-2-carboxamide and its related analogues
CA2789474A1 (en) * 2010-03-04 2011-09-09 Merck Sharp & Dohme Corp. Inhibitors of catechol o-methyl transferase and their use in the treatment of psychotic disorders
GB201007209D0 (en) 2010-04-29 2010-06-16 King S College London Compound
WO2012137202A1 (en) 2011-04-05 2012-10-11 Yissum Research Development Company Of The Hebrew University Of Jerusalem Ltd. Composition comprising an iron indicator attached to a microparticle and uses of same for quantifying non-transferrin bound iron (ntbi) and cellular labile iron (lci)
US10821103B2 (en) 2016-11-07 2020-11-03 Arbutus Biopharma Corporation Substituted pyridinone-containing trycyclic compounds, and methods using same
TWI801517B (zh) 2018-03-12 2023-05-11 加拿大商愛彼特生物製藥公司 經取代的2-吡啶酮三環化合物、其類似物及其使用方法
TW202010499A (zh) 2018-04-12 2020-03-16 加拿大商愛彼特生物製藥公司 經取代的吡啶酮之三環化合物的製備方法

Also Published As

Publication number Publication date
US4840958A (en) 1989-06-20
EP0093498A2 (en) 1983-11-09
JPH0460987B2 (nl) 1992-09-29
JPH0757749B2 (ja) 1995-06-21
DE19975062I1 (de) 2003-09-04
HK6190A (en) 1990-02-02
NL990031I1 (nl) 1999-12-01
DE3367849D1 (en) 1987-01-15
JPS58174319A (ja) 1983-10-13
EP0093498B1 (en) 1986-11-26
JPH0680636A (ja) 1994-03-22
GR78491B (nl) 1984-09-27
EP0093498A3 (en) 1984-07-11
CY1502A (en) 1990-08-03
JPS58174318A (ja) 1983-10-13
JPH0515693B2 (nl) 1993-03-02

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