FR2348219A1 - Procede de preparation d'isomeres syn de composes d'acides 3,7-cephem-4-carboxyliques 3,7-disubstitues et nouveaux produits ainsi obtenus, a activite antibacterienne - Google Patents

Procede de preparation d'isomeres syn de composes d'acides 3,7-cephem-4-carboxyliques 3,7-disubstitues et nouveaux produits ainsi obtenus, a activite antibacterienne

Info

Publication number
FR2348219A1
FR2348219A1 FR7707173A FR7707173A FR2348219A1 FR 2348219 A1 FR2348219 A1 FR 2348219A1 FR 7707173 A FR7707173 A FR 7707173A FR 7707173 A FR7707173 A FR 7707173A FR 2348219 A1 FR2348219 A1 FR 2348219A1
Authority
FR
France
Prior art keywords
cephem
carboxylic
acid compounds
antibacterial activity
new products
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7707173A
Other languages
English (en)
French (fr)
Other versions
FR2348219B1 (US20080094685A1-20080424-C00004.png
Inventor
Takao Takaya
Takashi Masugi
Hisashi Takasugi
Hiromu Kochi
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Fujisawa Pharmaceutical Co Ltd
Original Assignee
Fujisawa Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB14916/76A external-priority patent/GB1576625A/en
Application filed by Fujisawa Pharmaceutical Co Ltd filed Critical Fujisawa Pharmaceutical Co Ltd
Publication of FR2348219A1 publication Critical patent/FR2348219A1/fr
Priority to FR7802762A priority Critical patent/FR2367756B1/fr
Application granted granted Critical
Publication of FR2348219B1 publication Critical patent/FR2348219B1/fr
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D277/38—Nitrogen atoms
    • C07D277/44—Acylated amino or imino radicals
    • C07D277/48—Acylated amino or imino radicals by radicals derived from carbonic acid, or sulfur or nitrogen analogues thereof, e.g. carbonylguanidines
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/587—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with aliphatic hydrocarbon radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms, said aliphatic radicals being substituted in the alpha-position to the ring by a hetero atom, e.g. with m >= 0, Z being a singly or a doubly bound hetero atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
    • C07D333/06—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring carbon atoms
    • C07D333/14—Radicals substituted by singly bound hetero atoms other than halogen
    • C07D333/16—Radicals substituted by singly bound hetero atoms other than halogen by oxygen atoms
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Cephalosporin Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
FR7707173A 1976-04-12 1977-03-10 Procede de preparation d'isomeres syn de composes d'acides 3,7-cephem-4-carboxyliques 3,7-disubstitues et nouveaux produits ainsi obtenus, a activite antibacterienne Granted FR2348219A1 (fr)

Priority Applications (1)

Application Number Priority Date Filing Date Title
FR7802762A FR2367756B1 (fr) 1976-04-12 1978-02-01 Derives 2-alcoxyamino-2-(amino-1,3-thiazolyl) acetiques et leur utilisation

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB14916/76A GB1576625A (en) 1976-04-12 1976-04-12 Syn isomer 3,7 disubstituted 3 cephem 4 carboxylic acid compounds and processes for the preparation thereof
GB2349076 1976-06-07
JP51125826A JPS5941995B2 (ja) 1976-04-12 1976-10-19 ３，７−ジ置換−３−セフエム−４−カルボン酸化合物およびその塩類およびそれらの製造方法

Publications (2)

Publication Number Publication Date
FR2348219A1 true FR2348219A1 (fr) 1977-11-10
FR2348219B1 FR2348219B1 (US20080094685A1-20080424-C00004.png) 1982-12-03

Family

ID=27257189

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7707173A Granted FR2348219A1 (fr) 1976-04-12 1977-03-10 Procede de preparation d'isomeres syn de composes d'acides 3,7-cephem-4-carboxyliques 3,7-disubstitues et nouveaux produits ainsi obtenus, a activite antibacterienne

Country Status (13)

Country Link
AR (2) AR227864A1 (US20080094685A1-20080424-C00004.png)
AT (1) AT358728B (US20080094685A1-20080424-C00004.png)
CA (1) CA1337522C (US20080094685A1-20080424-C00004.png)
CH (2) CH638532A5 (US20080094685A1-20080424-C00004.png)
DE (1) DE2707565A1 (US20080094685A1-20080424-C00004.png)
DK (1) DK162391C (US20080094685A1-20080424-C00004.png)
ES (7) ES457191A1 (US20080094685A1-20080424-C00004.png)
FR (1) FR2348219A1 (US20080094685A1-20080424-C00004.png)
HU (1) HU177441B (US20080094685A1-20080424-C00004.png)
IE (1) IE45597B1 (US20080094685A1-20080424-C00004.png)
MX (1) MX4985E (US20080094685A1-20080424-C00004.png)
NL (1) NL191259C (US20080094685A1-20080424-C00004.png)
SE (2) SE443981B (US20080094685A1-20080424-C00004.png)

Cited By (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2348218A1 (fr) * 1976-04-14 1977-11-10 Takeda Chemical Industries Ltd Nouveaux derives cephalosporines ayant un nouveau groupe 7-acyle et leur procede de fabrication
FR2399418A1 (fr) * 1977-03-14 1979-03-02 Fujisawa Pharmaceutical Co Procede de preparation d'acides iminoacetiques et nouveaux produits ainsi obtenus, utilises pour la synthese d'acides cepham- ou cephem-carboxyliques
FR2421907A1 (fr) * 1978-04-07 1979-11-02 Roussel Uclaf Nouvelles cephalosporines derivees de l'acide 7-/2-(2-amino 4-thiazolyl)2-(carboxymethoxyimino/acetamido 3-substitue cephalosporanique, leur procede de preparation et leur application comme medicaments
EP0007633A2 (en) * 1978-07-31 1980-02-06 Fujisawa Pharmaceutical Co., Ltd. Cephem compounds, processes for their preparation and pharmaceutical compositions containing them
FR2432521A1 (fr) * 1978-03-31 1980-02-29 Roussel Uclaf Nouvelles oximes o-substituees derivees de l'acide 7-amino thiazolyl acetamido cephalosporanique, leur procede de preparation et leur application comme medicaments
FR2438051A2 (fr) * 1978-10-05 1980-04-30 Roussel Uclaf Nouvelles oximes derivees de l'acide 3-azidomethyl 7-amino thiazolyl acetamido cephalosporanique, leur procede de preparation et leur application comme medicaments
FR2453161A1 (fr) * 1978-08-31 1980-10-31 Fujisawa Pharmaceutical Co Procede de preparation de derives d'acide thiazolylacetique et nouveaux produits ainsi obtenus
EP0023453A1 (fr) * 1979-07-26 1981-02-04 Roussel-Uclaf Nouveau procédé de préparation de produits dérivés de l'acide 7-/(2-aryl)2-hydroxyimino acétamido/céphalosporanique
FR2475046A1 (fr) * 1979-12-07 1981-08-07 Erba Farmitalia Nouveaux derives (2-imino-4-thiazolyl)-substitues d'oximinocephalosporines, utiles notamment comme agents antibacteriens, et leur procede de preparation
FR2506307A1 (fr) * 1981-05-22 1982-11-26 Roussel Uclaf Nouveaux derives substitues de l'acide 2-(2-amino 4-thiazolyl) 2-hydroxyimino acetique et leur procede de preparation
EP0091277A2 (en) * 1982-04-01 1983-10-12 Eli Lilly And Company Dimethylacetamide solvate of syn-(2-amino thiazol-4-yl)(methoxyimino)acetic acid
FR2532936A1 (fr) * 1982-09-13 1984-03-16 Roussel Uclaf Nouveaux derives de l'acide 2-amino-thiazolyl-4-yl acetique comportant une fonction oxime substituee et leur procede de preparation
FR2551749A1 (fr) * 1983-09-09 1985-03-15 Glaxo Group Ltd Procede de separation d'un melange d'oximes isomeres syn et anti
FR2551757A1 (fr) * 1983-09-12 1985-03-15 Biochemie Gmbh Nouveau procede de preparation d'antibiotiques du type cephalosporine
FR2553770A2 (fr) * 1978-03-31 1985-04-26 Roussel Uclaf Nouveaux produits derives de l'acide 2(2-amino thiazol-4-yl) 2-alcoxy-imino acetique substitues sur l'oxime et leur procede de preparation
FR2564840A1 (fr) * 1984-05-25 1985-11-29 Toyama Chemical Co Ltd Procede de production d'une cephalosporine, un intermediaire de synthese de cette cephalosporine et un procede de production de cet intermediaire
EP0241901A2 (en) * 1986-04-14 1987-10-21 Banyu Pharmaceutical Co., Ltd. Cephalosporin derivatives, processes for their preparation and antibacterial agents

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3192167A (en) * 1962-09-20 1965-06-29 Ogawa Abiko Low pressure liquid vaporizer which is electrically heated
BE878514A (fr) * 1978-09-04 1980-02-29 Fujisawa Pharmaceutical Co Procede de preparation de composes d'acide 3-cephem-4-carboxylique a disubstitution en positions 3 et 7, nouveaux produits ainsi obtenus et leur utilisation pour leur activite antibacterienne
FR2381053A1 (fr) * 1977-02-18 1978-09-15 Roussel Uclaf Nouvelles oximes derivees de l'acide 3-thiadiazolyl thiomethyl 7-aminothiazolyl acetamido cephalosporanique, leur procede de preparation et leur application comme medicaments
PH17188A (en) 1977-03-14 1984-06-14 Fujisawa Pharmaceutical Co New cephem and cepham compounds and their pharmaceutical compositions and method of use
SE439312B (sv) * 1977-03-25 1985-06-10 Roussel Uclaf Sett att framstella nya oximderivat av 3-acetoximetyl-7-aminotiazolylacetamido cefalosporansyra
DE2714880A1 (de) * 1977-04-02 1978-10-26 Hoechst Ag Cephemderivate und verfahren zu ihrer herstellung
JPS5498795A (en) * 1978-01-13 1979-08-03 Takeda Chem Ind Ltd Cephalosporin derivative and its preparation
MC1259A1 (fr) * 1978-05-30 1980-01-14 Hoffmann La Roche Derives acyles
US4341775A (en) * 1978-09-11 1982-07-27 Fujisawa Pharmaceutical Co., Ltd. Cephem compounds
DE2965943D1 (en) * 1978-10-17 1983-08-25 Fujisawa Pharmaceutical Co Cepham compounds, pharmaceutical compositions containing them and processes for the preparation thereof and of known cephem compounds
DE2945248A1 (de) * 1978-11-13 1980-05-22 Fujisawa Pharmaceutical Co Cephem-verbindungen, verfahren zu ihrer herstellung und sie enthaltende antibakterielle pharmazeutische mittel
FR2448543A1 (fr) * 1979-02-09 1980-09-05 Roussel Uclaf Nouvelles oximes o-substituees par un radical comportant un ammonium quaternaire et derivees de l'acide 7-amino thiazolyl acetamido cephalosporanique, leur procede de preparation et leur application comme medicaments
FR2461713A1 (fr) * 1979-07-19 1981-02-06 Roussel Uclaf Nouvelles alcoyloximes substituees derivees de l'acide 7-(2-amino 4-thiazolyl) acetamido cephalosporanique, leur procede de preparation et leur application comme medicaments

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2137899A1 (US20080094685A1-20080424-C00004.png) * 1971-05-14 1972-12-29 Glaxo Lab Ltd
FR2345153A1 (fr) * 1976-03-25 1977-10-21 Roussel Uclaf Nouvelles alcoyloximes derivees de l'acide 7-amino thiazolyl acetamido cephalosporanique, leur procede de preparation et leur application comme medicaments
FR2346014A1 (fr) * 1976-01-23 1977-10-28 Roussel Uclaf Nouvelles oximes derivees de l'acide 7-amino thiazolyl acetamido cephalosporanique, leur procede de preparation et leur application comme medicaments
FR2348218A1 (fr) * 1976-04-14 1977-11-10 Takeda Chemical Industries Ltd Nouveaux derives cephalosporines ayant un nouveau groupe 7-acyle et leur procede de fabrication

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ176206A (en) * 1973-12-25 1978-03-06 Takeda Chemical Industries Ltd Cephalosporins
DK154939C (da) * 1974-12-19 1989-06-12 Takeda Chemical Industries Ltd Analogifremgangsmaade til fremstilling af thiazolylacetamido-cephemforbindelser eller farmaceutisk acceptable salte eller estere deraf
SE432254B (sv) * 1975-02-04 1984-03-26 Fujisawa Pharmaceutical Co Analogiforfarande for framstellning av 3-substituerade 7-(alfa,alfa-disubstituerade acetamido)-3-cefem-4-karboxylsyror
DE2760123C2 (de) * 1976-01-23 1986-04-30 Roussel-Uclaf, Paris 7-Aminothiazolyl-syn-oxyiminoacetamidocephalosporansäuren, ihre Herstellung und sie enthaltende pharmazeutische Zusammensetzungen
SE440655B (sv) * 1976-01-23 1985-08-12 Roussel Uclaf Sett att framstella nya oximderivat av 7-amino-tiazolyl-acetamido-cefalosporansyra

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2137899A1 (US20080094685A1-20080424-C00004.png) * 1971-05-14 1972-12-29 Glaxo Lab Ltd
FR2346014A1 (fr) * 1976-01-23 1977-10-28 Roussel Uclaf Nouvelles oximes derivees de l'acide 7-amino thiazolyl acetamido cephalosporanique, leur procede de preparation et leur application comme medicaments
FR2345153A1 (fr) * 1976-03-25 1977-10-21 Roussel Uclaf Nouvelles alcoyloximes derivees de l'acide 7-amino thiazolyl acetamido cephalosporanique, leur procede de preparation et leur application comme medicaments
FR2348218A1 (fr) * 1976-04-14 1977-11-10 Takeda Chemical Industries Ltd Nouveaux derives cephalosporines ayant un nouveau groupe 7-acyle et leur procede de fabrication

Cited By (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2348218A1 (fr) * 1976-04-14 1977-11-10 Takeda Chemical Industries Ltd Nouveaux derives cephalosporines ayant un nouveau groupe 7-acyle et leur procede de fabrication
FR2399418A1 (fr) * 1977-03-14 1979-03-02 Fujisawa Pharmaceutical Co Procede de preparation d'acides iminoacetiques et nouveaux produits ainsi obtenus, utilises pour la synthese d'acides cepham- ou cephem-carboxyliques
FR2432521A1 (fr) * 1978-03-31 1980-02-29 Roussel Uclaf Nouvelles oximes o-substituees derivees de l'acide 7-amino thiazolyl acetamido cephalosporanique, leur procede de preparation et leur application comme medicaments
FR2553770A2 (fr) * 1978-03-31 1985-04-26 Roussel Uclaf Nouveaux produits derives de l'acide 2(2-amino thiazol-4-yl) 2-alcoxy-imino acetique substitues sur l'oxime et leur procede de preparation
FR2421907A1 (fr) * 1978-04-07 1979-11-02 Roussel Uclaf Nouvelles cephalosporines derivees de l'acide 7-/2-(2-amino 4-thiazolyl)2-(carboxymethoxyimino/acetamido 3-substitue cephalosporanique, leur procede de preparation et leur application comme medicaments
EP0049539A1 (en) * 1978-07-31 1982-04-14 Fujisawa Pharmaceutical Co., Ltd. Thiazole derivatives for preparing cephem compounds and processes for their preparation
EP0007633A2 (en) * 1978-07-31 1980-02-06 Fujisawa Pharmaceutical Co., Ltd. Cephem compounds, processes for their preparation and pharmaceutical compositions containing them
EP0007633A3 (en) * 1978-07-31 1980-06-25 Fujisawa Pharmaceutical Co. Ltd. Cephem compounds, processes for their preparation, pharmaceutical compositions containing them, their starting derivatives and their preparation
FR2453161A1 (fr) * 1978-08-31 1980-10-31 Fujisawa Pharmaceutical Co Procede de preparation de derives d'acide thiazolylacetique et nouveaux produits ainsi obtenus
FR2438051A2 (fr) * 1978-10-05 1980-04-30 Roussel Uclaf Nouvelles oximes derivees de l'acide 3-azidomethyl 7-amino thiazolyl acetamido cephalosporanique, leur procede de preparation et leur application comme medicaments
EP0023453A1 (fr) * 1979-07-26 1981-02-04 Roussel-Uclaf Nouveau procédé de préparation de produits dérivés de l'acide 7-/(2-aryl)2-hydroxyimino acétamido/céphalosporanique
FR2475046A1 (fr) * 1979-12-07 1981-08-07 Erba Farmitalia Nouveaux derives (2-imino-4-thiazolyl)-substitues d'oximinocephalosporines, utiles notamment comme agents antibacteriens, et leur procede de preparation
FR2506307A1 (fr) * 1981-05-22 1982-11-26 Roussel Uclaf Nouveaux derives substitues de l'acide 2-(2-amino 4-thiazolyl) 2-hydroxyimino acetique et leur procede de preparation
EP0091277A2 (en) * 1982-04-01 1983-10-12 Eli Lilly And Company Dimethylacetamide solvate of syn-(2-amino thiazol-4-yl)(methoxyimino)acetic acid
EP0091277A3 (en) * 1982-04-01 1984-12-27 Eli Lilly And Company Dimethylacetamide solvate of syn-(2-amino thiazol-4-yl)(methoxyimino)acetic acid
FR2532936A1 (fr) * 1982-09-13 1984-03-16 Roussel Uclaf Nouveaux derives de l'acide 2-amino-thiazolyl-4-yl acetique comportant une fonction oxime substituee et leur procede de preparation
FR2551749A1 (fr) * 1983-09-09 1985-03-15 Glaxo Group Ltd Procede de separation d'un melange d'oximes isomeres syn et anti
FR2551757A1 (fr) * 1983-09-12 1985-03-15 Biochemie Gmbh Nouveau procede de preparation d'antibiotiques du type cephalosporine
FR2564840A1 (fr) * 1984-05-25 1985-11-29 Toyama Chemical Co Ltd Procede de production d'une cephalosporine, un intermediaire de synthese de cette cephalosporine et un procede de production de cet intermediaire
US4656287A (en) * 1984-05-25 1987-04-07 Toyoma Chemical Co., Ltd. Aminothiazole intermediate for a cephalosporin
EP0241901A2 (en) * 1986-04-14 1987-10-21 Banyu Pharmaceutical Co., Ltd. Cephalosporin derivatives, processes for their preparation and antibacterial agents
EP0241901B1 (en) * 1986-04-14 1994-08-24 Banyu Pharmaceutical Co., Ltd. Cephalosporin derivatives, processes for their preparation and antibacterial agents

Also Published As

Publication number Publication date
ES485062A1 (es) 1980-06-16
CH643557A5 (en) 1984-06-15
DE2707565C2 (US20080094685A1-20080424-C00004.png) 1988-06-30
AR223143A1 (es) 1981-07-31
ES485061A1 (es) 1980-06-16
AT358728B (de) 1980-09-25
IE45597L (en) 1977-10-12
NL191259B (nl) 1994-11-16
ES457191A1 (es) 1978-08-16
ES485064A1 (es) 1980-10-01
ES485063A1 (es) 1980-06-16
FR2348219B1 (US20080094685A1-20080424-C00004.png) 1982-12-03
DK75077A (da) 1977-10-13
SE457351B (sv) 1988-12-19
NL191259C (nl) 1995-04-18
SE8304465D0 (sv) 1983-08-17
CA1337522C (en) 1995-11-07
SE443981B (sv) 1986-03-17
HU177441B (en) 1981-10-28
DE2707565A1 (de) 1978-02-23
NL7703969A (nl) 1977-10-14
ES477741A1 (es) 1980-04-01
MX4985E (es) 1983-01-31
ATA138477A (de) 1980-02-15
AR227864A1 (es) 1982-12-30
CH638532A5 (de) 1983-09-30
DK162391B (da) 1991-10-21
ES468719A1 (es) 1979-10-16
DK162391C (da) 1992-03-09
IE45597B1 (en) 1982-10-06
SE7701964L (sv) 1977-10-13

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