FR2345448A1 - Nouveaux peptides et leur procede de preparation - Google Patents

Nouveaux peptides et leur procede de preparation

Info

Publication number
FR2345448A1
FR2345448A1 FR7708576A FR7708576A FR2345448A1 FR 2345448 A1 FR2345448 A1 FR 2345448A1 FR 7708576 A FR7708576 A FR 7708576A FR 7708576 A FR7708576 A FR 7708576A FR 2345448 A1 FR2345448 A1 FR 2345448A1
Authority
FR
France
Prior art keywords
preparation process
new peptides
peptides
new
preparation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7708576A
Other languages
English (en)
Other versions
FR2345448B1 (fr
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Takeda Pharmaceutical Co Ltd
Original Assignee
Takeda Chemical Industries Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Takeda Chemical Industries Ltd filed Critical Takeda Chemical Industries Ltd
Publication of FR2345448A1 publication Critical patent/FR2345448A1/fr
Application granted granted Critical
Publication of FR2345448B1 publication Critical patent/FR2345448B1/fr
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/26—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D307/30—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D307/32—Oxygen atoms
    • C07D307/33—Oxygen atoms in position 2, the oxygen atom being in its keto or unsubstituted enol form
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/26—Psychostimulants, e.g. nicotine, cocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D279/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom and one sulfur atom as the only ring hetero atoms
    • C07D279/10—1,4-Thiazines; Hydrogenated 1,4-thiazines
    • C07D279/12—1,4-Thiazines; Hydrogenated 1,4-thiazines not condensed with other rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/08—Tripeptides
    • C07K5/0821—Tripeptides with the first amino acid being heterocyclic, e.g. His, Pro, Trp

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Molecular Biology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Diabetes (AREA)
  • Endocrinology (AREA)
  • Psychiatry (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
FR7708576A 1976-03-23 1977-03-22 Nouveaux peptides et leur procede de preparation Granted FR2345448A1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP51032170A JPS5944308B2 (ja) 1976-03-23 1976-03-23 ペプタイド

Publications (2)

Publication Number Publication Date
FR2345448A1 true FR2345448A1 (fr) 1977-10-21
FR2345448B1 FR2345448B1 (fr) 1980-06-27

Family

ID=12351453

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7708576A Granted FR2345448A1 (fr) 1976-03-23 1977-03-22 Nouveaux peptides et leur procede de preparation

Country Status (19)

Country Link
US (1) US4100152A (fr)
JP (1) JPS5944308B2 (fr)
AT (1) AT360674B (fr)
AU (1) AU508387B2 (fr)
BE (1) BE852740A (fr)
CA (1) CA1060435A (fr)
CH (1) CH634548A5 (fr)
DE (1) DE2712086C2 (fr)
DK (1) DK149111C (fr)
FR (1) FR2345448A1 (fr)
GB (1) GB1579264A (fr)
GR (1) GR62565B (fr)
HK (1) HK27584A (fr)
HU (1) HU177515B (fr)
MY (1) MY8500264A (fr)
NL (1) NL188412C (fr)
SE (1) SE430601B (fr)
SG (1) SG76083G (fr)
ZA (1) ZA771495B (fr)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2512673A1 (fr) * 1981-09-16 1983-03-18 Takeda Chemical Industries Ltd Sels physiologiquement acceptables de l'acide g-butyrolactone-g-carbonyl-histidyl-prolinamide, ayant des proprietes anti-epileptiques

Families Citing this family (32)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HU180926B (en) * 1979-06-28 1983-05-30 Richter Gedeon Vegyeszet Process for preparing trh analogues,tripeptide amides infectives on the central nerve sysrhem
US4591648A (en) * 1981-04-01 1986-05-27 National Research Development Corp. Histidine protection
US4426378A (en) 1981-04-09 1984-01-17 The United States Of America As Represented By The Secretary Of The Army Thyrotropin releasing hormone in therapy of shock and as a central nervous system stimulant
US4659696A (en) * 1982-04-30 1987-04-21 Takeda Chemical Industries, Ltd. Pharmaceutical composition and its nasal or vaginal use
GB2146026A (en) * 1983-09-07 1985-04-11 Tanabe Seiyaku Co Peptides and process for preparing the same
JPS60190795A (ja) * 1984-03-09 1985-09-28 Takeda Chem Ind Ltd ペプタイド
US4608365A (en) * 1984-03-30 1986-08-26 University Of Southern California Treatment of neurologic functions
IL75641A (en) * 1984-07-10 1990-11-05 Tanabe Seiyaku Co 1-methyl-4,5-dihydro-orotyl-histidyl-prolinamide,its preparation and pharmaceutical compositions comprising it
GB2171101A (en) * 1985-02-20 1986-08-20 Tanabe Seiyaku Co Peptide and processes for preparation of the same
FR2585709B1 (fr) * 1985-08-05 1987-10-02 Adir Nouveaux derives peptidiques a structure lactonique ou cycloamidique, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
JP2526589B2 (ja) * 1986-08-08 1996-08-21 武田薬品工業株式会社 ペプチド含有マイクロカプセルおよびその製造法
US5686420A (en) * 1987-06-05 1997-11-11 Georgetown University Thyrotropin-releasing hormone analogs and method of use
JPS63316724A (ja) * 1987-06-19 1988-12-26 Nippon Shinyaku Co Ltd 抗けいれん剤
US5151497A (en) * 1989-02-21 1992-09-29 Japan Tobacco Inc. Histidyl peptide derivatives
CA2050425A1 (fr) 1990-09-03 1992-03-04 Yoshiaki Uda Composition pharmaceutique et son utilisation avec du mucus
NZ240214A (en) 1990-10-16 1993-02-25 Takeda Chemical Industries Ltd Polymer compositions comprising a polylactic acid and a copolymer of glycolic acid and a hydroxycarboxylic acid; use as carrier for prolonged release pharmaceutical compositions of water soluble drugs
US5416071A (en) * 1991-03-12 1995-05-16 Takeda Chemical Industries, Ltd. Water-soluble composition for sustained-release containing epo and hyaluronic acid
EP0582459B1 (fr) 1992-08-07 1998-01-07 Takeda Chemical Industries, Ltd. Production de microcapsules de médicaments solubles dans l'eau
US6117455A (en) * 1994-09-30 2000-09-12 Takeda Chemical Industries, Ltd. Sustained-release microcapsule of amorphous water-soluble pharmaceutical active agent
US5837281A (en) 1995-03-17 1998-11-17 Takeda Chemical Industries, Ltd. Stabilized interface for iontophoresis
EP0862429A4 (fr) * 1995-10-24 2003-05-28 Gruenenthal Gmbh Methode d'ajustement du rythme circadien d'un mammifere
CA2192782C (fr) 1995-12-15 2008-10-14 Nobuyuki Takechi Production de microsphere
EP0813887A3 (fr) * 1996-06-20 1999-11-03 Hisamitsu Pharmaceutical Co. Inc. Appareil d'ionophorèse
DE69735543T2 (de) * 1996-08-28 2007-03-08 Shionogi & Co., Ltd. Neuartige peptidderivate mit thiazolyl-alanin-resten
US6410539B1 (en) * 1997-10-22 2002-06-25 Astrazenca Uk Limited Imidazole derivatives and their use as farnesyl protein transferase inhibitors
PT1025088E (pt) 1997-10-22 2002-01-30 Astrazeneca Ab Derivados de imidazole e sua utilizacao como inibidores de farnesil proteino transferase
JP2003528088A (ja) * 2000-03-23 2003-09-24 メルク エンド カムパニー インコーポレーテッド メラノコルチン受容体作働薬としての置換ピペリジン類
CN1283314C (zh) * 2000-08-31 2006-11-08 盐野义制药株式会社 抗帕金森氏病药
WO2002043709A1 (fr) 2000-12-01 2002-06-06 Takeda Chemical Industries, Ltd. Procede de production d'une preparation contenant une substance bioactive
GB0326632D0 (en) 2003-11-14 2003-12-17 Jagotec Ag Dry powder formulations
WO2012028745A1 (fr) 2010-09-03 2012-03-08 Pharmaterials Limited Composition pharmaceutique adaptée pour une utilisation dans un inhalateur de poudre sèche
US20150157619A1 (en) 2012-07-10 2015-06-11 Takeda Pharmaceutical Company Limited Pharmaceutical preparation for injection

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3753969A (en) * 1969-12-22 1973-08-21 K Folkers Method for synthesizing pyroglutamylhistidyl-prolinamide
US3821188A (en) * 1972-06-14 1974-06-28 American Home Prod Proline and pyroglutamic acid containing tripeptides
US3959248A (en) * 1974-04-03 1976-05-25 Merck & Co., Inc. Analogs of thyrotropin-releasing hormone
DE2449167C2 (de) * 1974-10-16 1984-05-24 Grünenthal GmbH, 5190 Stolberg N-Acyl-L-histidyl-L-prolinamide, Verfahren zu deren Herstellung und diese Verbindungen enthaltende pharmazeutische Zubereitungen

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2512673A1 (fr) * 1981-09-16 1983-03-18 Takeda Chemical Industries Ltd Sels physiologiquement acceptables de l'acide g-butyrolactone-g-carbonyl-histidyl-prolinamide, ayant des proprietes anti-epileptiques

Also Published As

Publication number Publication date
NL188412B (nl) 1992-01-16
FR2345448B1 (fr) 1980-06-27
CH634548A5 (de) 1983-02-15
MY8500264A (en) 1985-12-31
DK119577A (da) 1977-09-24
ZA771495B (en) 1978-02-22
DE2712086C2 (de) 1986-04-03
SE430601B (sv) 1983-11-28
NL188412C (nl) 1992-06-16
JPS5944308B2 (ja) 1984-10-29
DE2712086A1 (de) 1977-09-29
AU508387B2 (en) 1980-03-20
CA1060435A (fr) 1979-08-14
AU2354977A (en) 1978-09-28
HK27584A (en) 1984-03-30
GR62565B (en) 1979-05-10
SE7703283L (sv) 1977-09-24
ATA202377A (de) 1980-06-15
DK149111B (da) 1986-01-27
AT360674B (de) 1981-01-26
SG76083G (en) 1984-08-03
GB1579264A (en) 1980-11-19
DK149111C (da) 1986-06-09
HU177515B (en) 1981-10-28
NL7703115A (nl) 1977-09-27
US4100152A (en) 1978-07-11
BE852740A (fr) 1977-07-18
JPS52116465A (en) 1977-09-29

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Legal Events

Date Code Title Description
ST Notification of lapse