FR2332012B1 - - Google Patents

Info

Publication number
FR2332012B1
FR2332012B1 FR7634882A FR7634882A FR2332012B1 FR 2332012 B1 FR2332012 B1 FR 2332012B1 FR 7634882 A FR7634882 A FR 7634882A FR 7634882 A FR7634882 A FR 7634882A FR 2332012 B1 FR2332012 B1 FR 2332012B1
Authority
FR
France
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
FR7634882A
Other versions
FR2332012A1 (fr
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merck and Co Inc
Original Assignee
Merck and Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck and Co Inc filed Critical Merck and Co Inc
Publication of FR2332012A1 publication Critical patent/FR2332012A1/fr
Application granted granted Critical
Publication of FR2332012B1 publication Critical patent/FR2332012B1/fr
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D477/00—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring
    • C07D477/10—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2
    • C07D477/12—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2 with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, attached in position 6
    • C07D477/16—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2 with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, attached in position 6 with hetero atoms or carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 3
    • C07D477/20—Sulfur atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D205/00—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom
    • C07D205/02—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings
    • C07D205/06—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D205/08—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic System
    • C07F7/02—Silicon compounds
    • C07F7/08—Compounds having one or more C—Si linkages
    • C07F7/10—Compounds having one or more C—Si linkages containing nitrogen having a Si-N linkage
FR7634882A 1975-11-21 1976-11-19 Derives n-methylene substitues de thienamycine utiles comme antibiotiques Granted FR2332012A1 (fr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US63429675A 1975-11-21 1975-11-21
US67626176A 1976-04-12 1976-04-12
US73365476A 1976-10-18 1976-10-18

Publications (2)

Publication Number Publication Date
FR2332012A1 FR2332012A1 (fr) 1977-06-17
FR2332012B1 true FR2332012B1 (fr) 1978-11-17

Family

ID=27417545

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7634882A Granted FR2332012A1 (fr) 1975-11-21 1976-11-19 Derives n-methylene substitues de thienamycine utiles comme antibiotiques

Country Status (27)

Country Link
AT (1) AT358168B (fr)
AU (1) AU512383B2 (fr)
BG (1) BG34037A3 (fr)
CA (1) CA1083577A (fr)
CH (2) CH632510A5 (fr)
DD (1) DD127742A5 (fr)
DE (1) DE2652679A1 (fr)
DK (1) DK157401C (fr)
EG (1) EG12261A (fr)
ES (1) ES453501A1 (fr)
FI (1) FI62306C (fr)
FR (1) FR2332012A1 (fr)
GB (1) GB1570990A (fr)
GR (1) GR62072B (fr)
HK (1) HK29683A (fr)
HU (1) HU180865B (fr)
IE (1) IE44433B1 (fr)
IL (1) IL50911A (fr)
KE (1) KE3286A (fr)
NL (1) NL189297C (fr)
NO (1) NO153298C (fr)
NZ (1) NZ182630A (fr)
PH (1) PH16714A (fr)
PL (1) PL110937B1 (fr)
PT (1) PT65865B (fr)
SE (1) SE427841B (fr)
SG (1) SG10983G (fr)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1593524A (en) * 1976-11-19 1981-07-15 Merck & Co Inc 1-carba-2-penem-3-carboxylic acids
SE436569B (sv) * 1977-05-05 1985-01-07 Merck & Co Inc Analogiforfarande for framstellning av tienamycinderivat
US4232030A (en) * 1977-09-15 1980-11-04 Merck & Co., Inc. Substituted N-methylene derivatives of thienamycin sulfoxide and sulfone
DK153486C (da) * 1978-07-03 1988-11-28 Merck & Co Inc Analogifremgangsmaade til fremstilling af krystallinsk n-formimidoyl-thienamycin-monohydrat
EP0044170A1 (fr) * 1980-07-11 1982-01-20 Beecham Group Plc Antibiotiques bêta-lactame, leur préparation et leur utilisation
JPH06501002A (ja) * 1990-08-30 1994-01-27 オレゴン州 シグマ受容体に対して高い結合性を有する置換アミジン類およびその使用

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1004670A (en) * 1963-04-23 1965-09-15 Beecham Res Lab Penicillins
GB1348984A (en) * 1970-06-16 1974-03-27 Merck & Co Inc Antibiotics and processes for their production
US3950357A (en) * 1974-11-25 1976-04-13 Merck & Co., Inc. Antibiotics

Also Published As

Publication number Publication date
NL7612939A (nl) 1977-05-24
ES453501A1 (es) 1978-03-01
ATA863476A (de) 1980-01-15
NL189297B (nl) 1992-10-01
HK29683A (en) 1983-08-26
IE44433L (en) 1977-05-21
DE2652679A1 (de) 1977-06-02
NL189297C (nl) 1993-03-01
SE7612963L (sv) 1977-05-22
CH632510A5 (en) 1982-10-15
DE2652679C2 (fr) 1990-03-01
AU1964776A (en) 1978-05-25
SG10983G (en) 1983-12-16
GR62072B (en) 1979-02-20
AT358168B (de) 1980-08-25
HU180865B (en) 1983-04-29
PT65865B (en) 1978-10-12
PL193809A1 (pl) 1978-01-16
KE3286A (en) 1983-06-17
GB1570990A (en) 1980-07-09
FI763308A (fr) 1977-05-22
NZ182630A (en) 1979-07-11
NO763958L (fr) 1977-05-24
CH633800A5 (en) 1982-12-31
CA1083577A (fr) 1980-08-12
IL50911A0 (en) 1977-01-31
FI62306B (fi) 1982-08-31
PT65865A (en) 1976-12-01
PL110937B1 (en) 1980-08-30
EG12261A (en) 1978-12-31
PH16714A (en) 1984-01-25
DD127742A5 (de) 1977-10-12
AU512383B2 (en) 1980-10-09
SE427841B (sv) 1983-05-09
DK157401B (da) 1990-01-02
NO153298B (no) 1985-11-11
IE44433B1 (en) 1981-12-02
DK523576A (da) 1977-05-22
FR2332012A1 (fr) 1977-06-17
DK157401C (da) 1990-05-21
NO153298C (no) 1986-02-19
FI62306C (fi) 1982-12-10
BG34037A3 (en) 1983-06-15
IL50911A (en) 1981-01-30

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Legal Events

Date Code Title Description
CC Supplementary protection certificate (spc) laid open to the public (law of 25 june 1990)

Free format text: 92C0048, 920318

CB Supplementary protection certificate (spc) granted (law of 25 june 1990)

Free format text: 92C0048, 761119

CL Concession to grant licences