FR2298797A1 - Procede et disp - Google Patents

Procede et disp

Info

Publication number
FR2298797A1
FR2298797A1 FR7601679A FR7601679A FR2298797A1 FR 2298797 A1 FR2298797 A1 FR 2298797A1 FR 7601679 A FR7601679 A FR 7601679A FR 7601679 A FR7601679 A FR 7601679A FR 2298797 A1 FR2298797 A1 FR 2298797A1
Authority
FR
France
Prior art keywords
disp
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7601679A
Other languages
English (en)
French (fr)
Other versions
FR2298797B1 (enExample
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Forschungszentrum Juelich GmbH
Original Assignee
Kernforschungsanlage Juelich GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kernforschungsanlage Juelich GmbH filed Critical Kernforschungsanlage Juelich GmbH
Publication of FR2298797A1 publication Critical patent/FR2298797A1/fr
Application granted granted Critical
Publication of FR2298797B1 publication Critical patent/FR2298797B1/fr
Granted legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/483—Physical analysis of biological material
    • G01N33/487—Physical analysis of biological material of liquid biological material
    • G01N33/48707—Physical analysis of biological material of liquid biological material by electrical means
    • G01N33/48728—Investigating individual cells, e.g. by patch clamp, voltage clamp
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/05—Detecting, measuring or recording for diagnosis by means of electric currents or magnetic fields; Measuring using microwaves or radio waves
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M35/00—Means for application of stress for stimulating the growth of microorganisms or the generation of fermentation or metabolic products; Means for electroporation or cell fusion
    • C12M35/02—Electrical or electromagnetic means, e.g. for electroporation or for cell fusion
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10—Investigating individual particles
    • G01N15/1031—Investigating individual particles by measuring electrical or magnetic effects
    • G01N15/12—Investigating individual particles by measuring electrical or magnetic effects by observing changes in resistance or impedance across apertures when traversed by individual particles, e.g. by using the Coulter principle
    • G01N15/134—Devices using two or more apertures
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01R—MEASURING ELECTRIC VARIABLES; MEASURING MAGNETIC VARIABLES
    • G01R27/00—Arrangements for measuring resistance, reactance, impedance, or electric characteristics derived therefrom
    • G01R27/02—Measuring real or complex resistance, reactance, impedance, or other two-pole characteristics derived therefrom, e.g. time constant
    • G01R27/26—Measuring inductance or capacitance; Measuring quality factor, e.g. by using the resonance method; Measuring loss factor; Measuring dielectric constants ; Measuring impedance or related variables
    • G01R27/2617—Measuring dielectric properties, e.g. constants
    • G01R27/2635—Sample holders, electrodes or excitation arrangements, e.g. sensors or measuring cells
    • G01R27/2658—Cavities, resonators, free space arrangements, reflexion or interference arrangements
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/01—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials specially adapted for biological cells, e.g. blood cells
    • G01N2015/012—Red blood cells
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10—Investigating individual particles
    • G01N2015/1006—Investigating individual particles for cytology

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Physics & Mathematics (AREA)
  • Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Pathology (AREA)
  • General Physics & Mathematics (AREA)
  • Molecular Biology (AREA)
  • Organic Chemistry (AREA)
  • Analytical Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Immunology (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Electromagnetism (AREA)
  • Microbiology (AREA)
  • Sustainable Development (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Surgery (AREA)
  • General Engineering & Computer Science (AREA)
  • Medical Informatics (AREA)
  • Cell Biology (AREA)
  • Urology & Nephrology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Radiology & Medical Imaging (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Dispersion Chemistry (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Investigating Or Analyzing Materials By The Use Of Electric Means (AREA)
FR7601679A 1975-01-23 1976-01-22 Procede et disp Granted FR2298797A1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE2502621A DE2502621C3 (de) 1975-01-23 1975-01-23 Messung elastischer und dielektrischer Eigenschaften der Membran lebender Zellen

Publications (2)

Publication Number Publication Date
FR2298797A1 true FR2298797A1 (fr) 1976-08-20
FR2298797B1 FR2298797B1 (enExample) 1980-01-11

Family

ID=5937086

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7601679A Granted FR2298797A1 (fr) 1975-01-23 1976-01-22 Procede et disp

Country Status (5)

Country Link
US (1) US4055799A (enExample)
JP (1) JPS6013140B2 (enExample)
CH (1) CH594888A5 (enExample)
DE (1) DE2502621C3 (enExample)
FR (1) FR2298797A1 (enExample)

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2420763A1 (fr) * 1978-03-23 1979-10-19 Asahi Chemical Ind Methode et dispositif pour mesurer les caracteristiques de membranes de vesicules
FR2434399A1 (fr) * 1978-06-28 1980-03-21 Kernforschungsanlage Juelich Procede et installation pour determiner le claquage dielectrique et la dimension de particules enrobees par une membrane
FR2569477A1 (fr) * 1984-08-24 1986-02-28 Descartes Universite Rene Appareil et procede pour la determination de la deformabilite des globules rouges du sang
WO1994002846A1 (en) * 1992-07-24 1994-02-03 British Technology Group Ltd. Method of and apparatus for determining a property of a sample

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US4343782A (en) * 1978-04-20 1982-08-10 Shapiro Howard M Cytological assay procedure
US4472506A (en) * 1981-01-13 1984-09-18 Liburdy Robert P Method for determining cell membrane dielectric breakdown
US4368423A (en) * 1981-01-13 1983-01-11 Liburdy Robert P Apparatus for determining cell membrane dielectric breakdown
JPS5822946A (ja) * 1981-08-03 1983-02-10 Olympus Optical Co Ltd 境界面検出装置
US5310674A (en) * 1982-05-10 1994-05-10 Bar-Ilan University Apertured cell carrier
IL68507A (en) * 1982-05-10 1986-01-31 Univ Bar Ilan System and methods for cell selection
US5272081A (en) * 1982-05-10 1993-12-21 Bar-Ilan University System and methods for cell selection
US4528270A (en) * 1982-11-02 1985-07-09 Kabushiki Kaisya Advance Kaihatsu Kenkyujo Electrochemical method for detection and classification of microbial cell
AU594641B2 (en) * 1983-11-08 1990-03-15 Bar-Ilan University Apparatus & methods for cell selection
SE461499B (sv) * 1986-11-21 1990-02-26 Nobelpharma Ab Beninvaextkammare
US5389069A (en) * 1988-01-21 1995-02-14 Massachusetts Institute Of Technology Method and apparatus for in vivo electroporation of remote cells and tissue
DE68922390T2 (de) * 1988-10-21 1995-10-05 Molecular Devices Corp Verfahren und apparat zur messung der effekte von zellwirksamen mitteln auf lebende zellen.
US5278048A (en) * 1988-10-21 1994-01-11 Molecular Devices Corporation Methods for detecting the effect of cell affecting agents on living cells
GB2232769B (en) * 1989-06-13 1994-06-22 Timothy Charles Fisher Counting and volume measurement of particles and biological cells,and determination of their deformability
AU747114B2 (en) * 1994-09-30 2002-05-09 Electronic Diagnostics Pty Ltd Method and apparatus for diagnosis, detection of cell abnormalities and morphology of living systems
AUPM851694A0 (en) * 1994-09-30 1994-10-27 Barsamian, Sergei T New methods for diagnosis, detection of cell abnormalities and morphology of living systems
US5983131A (en) * 1995-08-11 1999-11-09 Massachusetts Institute Of Technology Apparatus and method for electroporation of tissue
US6010613A (en) * 1995-12-08 2000-01-04 Cyto Pulse Sciences, Inc. Method of treating materials with pulsed electrical fields
US6387707B1 (en) * 1996-04-25 2002-05-14 Bioarray Solutions Array Cytometry
CA2255599C (en) 1996-04-25 2006-09-05 Bioarray Solutions, Llc Light-controlled electrokinetic assembly of particles near surfaces
US5911223A (en) * 1996-08-09 1999-06-15 Massachusetts Institute Of Technology Introduction of modifying agents into skin by electroporation
US6085115A (en) * 1997-05-22 2000-07-04 Massachusetts Institite Of Technology Biopotential measurement including electroporation of tissue surface
CN1109101C (zh) * 1997-06-10 2003-05-21 塞托·帕尔斯科技公司 处理带有可变方向的电场的物质的方法和装置
EP0968275B1 (en) * 1997-06-10 2004-02-04 Cyto Pulse Sciences, Inc. Method and apparatus for treating materials with electrical fields having varying orientations
US6163719A (en) * 1997-09-09 2000-12-19 Sherman; Adam Jacob Biological membrane voltage estimator
US7244349B2 (en) * 1997-12-17 2007-07-17 Molecular Devices Corporation Multiaperture sample positioning and analysis system
JP3486171B2 (ja) 1997-12-17 2004-01-13 エコル・ポリテクニック・フェデラル・ドゥ・ロザンヌ（エ・ペー・エフ・エル） ミクロ構造キャリア上における細胞単体および再構成膜系のポジショニングおよび電気生理学的特性決定
US20020144905A1 (en) 1997-12-17 2002-10-10 Christian Schmidt Sample positioning and analysis system
GB9812783D0 (en) 1998-06-12 1998-08-12 Cenes Ltd High throuoghput screen
JP4294142B2 (ja) 1999-02-02 2009-07-08 株式会社日立製作所 ディスクサブシステム
US6488829B1 (en) * 1999-08-05 2002-12-03 Essen Instruments Inc High-throughput electrophysiological measurement apparatus
DE19946458C2 (de) * 1999-09-28 2002-10-24 Fraunhofer Ges Forschung Vorrichtung und Verfahren zur Charakterisierung von Sphäroiden
US6682649B1 (en) * 1999-10-01 2004-01-27 Sophion Bioscience A/S Substrate and a method for determining and/or monitoring electrophysiological properties of ion channels
GB9930719D0 (en) * 1999-12-24 2000-02-16 Central Research Lab Ltd Apparatus for and method of making electrical measurements on an object in a m edium
GB9930718D0 (en) * 1999-12-24 2000-02-16 Central Research Lab Ltd Apparatus for and method of making electrical measurements on objects
US9709559B2 (en) 2000-06-21 2017-07-18 Bioarray Solutions, Ltd. Multianalyte molecular analysis using application-specific random particle arrays
CA2635452A1 (en) 2000-06-21 2001-12-27 Bioarray Solutions, Ltd. Looped probe design to control hybridization stringency
EP1178315A1 (de) * 2000-07-31 2002-02-06 Albrecht Dr.med. Priv.Doz. Lepple-Wienhues Verfahren und Vorrichtung zur Untersuchung von Zellen mit Hilfe der Patch Clamp-Methode
US7067046B2 (en) * 2000-08-04 2006-06-27 Essen Instruments, Inc. System for rapid chemical activation in high-throughput electrophysiological measurements
US7270730B2 (en) * 2000-08-04 2007-09-18 Essen Instruments, Inc. High-throughput electrophysiological measurement system
US20060029955A1 (en) * 2001-03-24 2006-02-09 Antonio Guia High-density ion transport measurement biochip devices and methods
US20050196746A1 (en) * 2001-03-24 2005-09-08 Jia Xu High-density ion transport measurement biochip devices and methods
US20040146849A1 (en) * 2002-01-24 2004-07-29 Mingxian Huang Biochips including ion transport detecting structures and methods of use
WO2002077259A2 (en) * 2001-03-24 2002-10-03 Aviva Biosciences Corporation Biochips including ion transport detecting structures and methods of use
US20050058990A1 (en) * 2001-03-24 2005-03-17 Antonio Guia Biochip devices for ion transport measurement, methods of manufacture, and methods of use
US20050009004A1 (en) * 2002-05-04 2005-01-13 Jia Xu Apparatus including ion transport detecting structures and methods of use
US7262063B2 (en) 2001-06-21 2007-08-28 Bio Array Solutions, Ltd. Directed assembly of functional heterostructures
WO2003011553A1 (en) * 2001-07-31 2003-02-13 Massachusetts Institute Of Technology On-chip membrane maker
JP4377689B2 (ja) 2001-10-15 2009-12-02 バイオアレイ ソリューションズ リミテッド 同時尋問及び酵素仲介検出による多型遺伝子座の複合分析
CA2485099C (en) * 2002-05-04 2017-09-26 Aviva Biosciences Corporation Apparatus including ion transport detecting structures and methods of use
EP1569510B1 (en) 2002-09-27 2011-11-02 The General Hospital Corporation Microfluidic device for cell separation and uses thereof
WO2004047007A1 (en) 2002-11-15 2004-06-03 Bioarray Solutions, Ltd. Analysis, secure access to, and transmission of array images
AU2003902363A0 (en) * 2003-05-15 2003-05-29 Life Therapeutics Limited Cell separation
US7927796B2 (en) 2003-09-18 2011-04-19 Bioarray Solutions, Ltd. Number coding for identification of subtypes of coded types of solid phase carriers
CA2539824C (en) 2003-09-22 2015-02-03 Xinwen Wang Surface immobilized polyelectrolyte with multiple functional groups capable of covalently bonding to biomolecules
DE602004019804D1 (de) * 2003-10-07 2009-04-16 Univ Newcastle Res Ass Trennung von spermazellen durch elektrophorese
US7563569B2 (en) 2003-10-28 2009-07-21 Michael Seul Optimization of gene expression analysis using immobilized capture probes
JP2007509629A (ja) 2003-10-29 2007-04-19 バイオアレイ ソリューションズ リミテッド 二本鎖ｄｎａの切断による複合核酸分析
US7169609B2 (en) * 2004-03-31 2007-01-30 Vertex Pharmaceutcals, Inc. Multiwell plate assembly for use in high throughput assays
DE102004017474A1 (de) * 2004-04-08 2005-10-27 Evotec Technologies Gmbh Messeinrichtung zur Impedanzspektroskopie und zugehöriges Messverfahren
DE112005001781B4 (de) * 2004-07-23 2017-12-14 Electronic Biosciences, Inc. Verfahren und Vorrichtung zum Messen eines zeitveränderlichen, durch einen Ionenkanal fließenden Stroms mit einer kapazitiven Messelektrode
US7848889B2 (en) 2004-08-02 2010-12-07 Bioarray Solutions, Ltd. Automated analysis of multiplexed probe-target interaction patterns: pattern matching and allele identification
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US20070196820A1 (en) 2005-04-05 2007-08-23 Ravi Kapur Devices and methods for enrichment and alteration of cells and other particles
US8486629B2 (en) 2005-06-01 2013-07-16 Bioarray Solutions, Ltd. Creation of functionalized microparticle libraries by oligonucleotide ligation or elongation
US8921102B2 (en) 2005-07-29 2014-12-30 Gpb Scientific, Llc Devices and methods for enrichment and alteration of circulating tumor cells and other particles
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US20140045252A1 (en) * 2011-04-28 2014-02-13 Hitachi, Ltd. Cell cultivation container and cell culturing apparatus
CA2852672C (en) * 2011-10-17 2021-07-20 Massachusetts Institute Of Technology A microfluidic system and method for delivering a payload into a cell by causing perturbations in a cell membrane of the cell
JP6502940B2 (ja) 2013-08-16 2019-04-17 マサチューセッツ インスティテュート オブ テクノロジー 細胞への物質の選択的送達
CN104232478A (zh) * 2014-09-24 2014-12-24 昆山超强光电设备有限公司 一种细菌数量采集器
AU2015338893A1 (en) 2014-10-31 2017-05-04 Massachusetts Institute Of Technology Delivery of biomolecules to immune cells
CN113897285A (zh) 2014-11-14 2022-01-07 麻省理工学院 化合物和组合物向细胞中的破坏和场实现的递送
AU2016206870B2 (en) 2015-01-12 2022-02-17 Massachusetts Institute Of Technology Gene editing through microfluidic delivery
CN107922911A (zh) 2015-07-09 2018-04-17 麻省理工学院 将物质递送至无核细胞
EP3344575B1 (en) 2015-09-04 2020-04-15 SQZ Biotechnologies Company Intracellular delivery of biomolecules to cells comprising a cell wall
SG11201809437TA (en) 2016-05-03 2018-11-29 Sqz Biotechnologies Co Intracellular delivery of biomolecules to induce tolerance
US11692168B2 (en) 2019-02-28 2023-07-04 Sqz Biotechnologies Company Delivery of biomolecules to PBMCs to modify an immune response
AU2020271040B2 (en) 2019-04-08 2025-07-03 Sqz Biotechnologies Company Cartridge for use in a system for delivery of a payload into a cell
CN112525792A (zh) * 2020-11-05 2021-03-19 中国电子科技集团公司第十八研究所 一种基于压力控制的锂电池隔膜温度测试装置及测试方法
CN118032535B (zh) * 2024-01-12 2024-10-22 天科新能源有限责任公司 一种聚合物固态电池的隔膜力学性能模拟测试系统

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US3560754A (en) * 1965-11-17 1971-02-02 Ibm Photoelectric particle separator using time delay
GB1262749A (en) * 1969-02-24 1972-02-02 Nat Res Dev Methods and apparatus for determining the condition of food
US3772593A (en) * 1971-11-03 1973-11-13 P Sidhu Resistance measurement system

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2420763A1 (fr) * 1978-03-23 1979-10-19 Asahi Chemical Ind Methode et dispositif pour mesurer les caracteristiques de membranes de vesicules
FR2434399A1 (fr) * 1978-06-28 1980-03-21 Kernforschungsanlage Juelich Procede et installation pour determiner le claquage dielectrique et la dimension de particules enrobees par une membrane
FR2569477A1 (fr) * 1984-08-24 1986-02-28 Descartes Universite Rene Appareil et procede pour la determination de la deformabilite des globules rouges du sang
WO1994002846A1 (en) * 1992-07-24 1994-02-03 British Technology Group Ltd. Method of and apparatus for determining a property of a sample
US5691633A (en) * 1992-07-24 1997-11-25 British Technology Group Limited Method of and apparatus for determining a property of a sample

Also Published As

Publication number Publication date
JPS5197495A (enExample) 1976-08-27
DE2502621B2 (de) 1978-01-12
FR2298797B1 (enExample) 1980-01-11
JPS6013140B2 (ja) 1985-04-05
CH594888A5 (enExample) 1978-01-31
DE2502621C3 (de) 1978-09-14
US4055799A (en) 1977-10-25
DE2502621A1 (de) 1976-08-05

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Legal Events

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TP Transmission of property
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