FR2263752A1 - 1,8-Naphthyridine derivs - tranquillizers and anti-convulsants - Google Patents
1,8-Naphthyridine derivs - tranquillizers and anti-convulsantsInfo
- Publication number
- FR2263752A1 FR2263752A1 FR7408730A FR7408730A FR2263752A1 FR 2263752 A1 FR2263752 A1 FR 2263752A1 FR 7408730 A FR7408730 A FR 7408730A FR 7408730 A FR7408730 A FR 7408730A FR 2263752 A1 FR2263752 A1 FR 2263752A1
- Authority
- FR
- France
- Prior art keywords
- naphthyridine
- tranquillizers
- convulsants
- alkyl
- derivs
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- FLBAYUMRQUHISI-UHFFFAOYSA-N 1,8-naphthyridine Chemical compound N1=CC=CC2=CC=CN=C21 FLBAYUMRQUHISI-UHFFFAOYSA-N 0.000 title abstract 2
- 230000001773 anti-convulsant effect Effects 0.000 title 1
- 229940125681 anticonvulsant agent Drugs 0.000 title 1
- 239000001961 anticonvulsive agent Substances 0.000 title 1
- 125000000217 alkyl group Chemical group 0.000 abstract 3
- GLUUGHFHXGJENI-UHFFFAOYSA-N Piperazine Chemical compound C1CNCCN1 GLUUGHFHXGJENI-UHFFFAOYSA-N 0.000 abstract 2
- 125000003342 alkenyl group Chemical group 0.000 abstract 2
- 125000003545 alkoxy group Chemical group 0.000 abstract 2
- 125000002768 hydroxyalkyl group Chemical group 0.000 abstract 2
- ZFRUGZMCGCYBRC-UHFFFAOYSA-N 1h-1,8-naphthyridin-2-one Chemical compound C1=CC=NC2=NC(O)=CC=C21 ZFRUGZMCGCYBRC-UHFFFAOYSA-N 0.000 abstract 1
- BVKZGUZCCUSVTD-UHFFFAOYSA-L Carbonate Chemical compound [O-]C([O-])=O BVKZGUZCCUSVTD-UHFFFAOYSA-L 0.000 abstract 1
- 125000000304 alkynyl group Chemical group 0.000 abstract 1
- AKGSNUOZGBDODP-UHFFFAOYSA-N piperazine-1-carbonyl chloride Chemical compound ClC(=O)N1CCNCC1 AKGSNUOZGBDODP-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D519/00—Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/26—Psychostimulants, e.g. nicotine, cocaine
Landscapes
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Neurosurgery (AREA)
- Life Sciences & Earth Sciences (AREA)
- Neurology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Biomedical Technology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Pain & Pain Management (AREA)
- Psychiatry (AREA)
- Anesthesiology (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Priority Applications (42)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR7408730A FR2263752A1 (en) | 1974-03-14 | 1974-03-14 | 1,8-Naphthyridine derivs - tranquillizers and anti-convulsants |
| OA55189A OA04700A (fr) | 1973-05-15 | 1974-04-29 | Nouveaux dérivés de la naphtyridine et leur procédé de préparation. |
| PH15794A PH11400A (en) | 1973-05-15 | 1974-04-30 | Naphthyridine derivatives and pharmaceutical composition thereof |
| NL7406194A NL7406194A (online.php) | 1973-05-15 | 1974-05-08 | |
| HURO780A HU169609B (online.php) | 1973-05-15 | 1974-05-13 | |
| IL44815A IL44815A (en) | 1973-05-15 | 1974-05-13 | 3-(piperazin-1-yl) carbonyloxy (naphthyridin-2-yl) isoindolinones pyrrolo (3,4-b) pyrazines and pyrrolo (3,4-b) pyridines processes for the preparation thereof and pharmaceutical compositions containing the same |
| IE1012/74A IE39263B1 (en) | 1973-05-15 | 1974-05-13 | Naphthyridine derivatives |
| JP49052378A JPS5758345B2 (online.php) | 1973-05-15 | 1974-05-13 | |
| GB2108174A GB1417935A (en) | 1973-05-15 | 1974-05-13 | Naphthyridine derivatives |
| AU68880/74A AU478373B2 (en) | 1973-05-15 | 1974-05-13 | Naphthyridine derivatives |
| SU7402026597A SU583757A3 (ru) | 1973-05-15 | 1974-05-14 | Способ получени производных нафтиридина или их солей |
| SE7406452A SE410857B (sv) | 1973-05-15 | 1974-05-14 | Forfarande for framstellning av nya derivat av naftyridin |
| MX561874U MX4617E (es) | 1973-05-15 | 1974-05-14 | Procedimiento para la preparacion de derivados de la naftiridina |
| ES426337A ES426337A1 (es) | 1974-03-14 | 1974-05-14 | Procedimiento para preparar derivados de naftiridina. |
| DD178499A DD111078A5 (online.php) | 1973-05-15 | 1974-05-14 | |
| CH53477A CH592663A5 (online.php) | 1973-05-15 | 1974-05-14 | |
| LU70071A LU70071A1 (online.php) | 1973-05-15 | 1974-05-14 | |
| DK263374AA DK136819B (da) | 1973-05-15 | 1974-05-14 | Analogifremgangsmåde til fremstilling af derivater af naphthyridin eller syreadditionssalte deraf. |
| NO741744A NO140012C (no) | 1973-05-15 | 1974-05-14 | Analogifremgangsmaate for fremstilling av nye terapeutisk aktive derivater av naftyridin |
| CH659574A CH592662A5 (online.php) | 1973-05-15 | 1974-05-14 | |
| CA199,810A CA1012971A (fr) | 1973-05-15 | 1974-05-14 | Derives de la naphtyridine, leur preparation et les compositions qui les contiennent |
| ES426336A ES426336A1 (es) | 1973-05-15 | 1974-05-14 | Procedimiento para preparar derivados de naftiridina. |
| ES426335A ES426335A1 (es) | 1973-05-15 | 1974-05-14 | Procedimiento para preparar derivados de naftiridina. |
| PL18664174A PL94204B1 (online.php) | 1973-05-15 | 1974-05-15 | |
| YU01336/74A YU133674A (en) | 1973-05-15 | 1974-05-15 | Process for obtaining new naphthiridine derivatives |
| CS743472A CS191881B2 (en) | 1973-05-15 | 1974-05-15 | Method of producing novel derivatives of naphtyridine |
| AT400874A AT336030B (de) | 1973-05-15 | 1974-05-15 | Verfahren zur herstellung von neuen naphthyridinderivaten und von deren saureadditionssalzen |
| AR253755A AR209421A1 (es) | 1973-05-15 | 1974-05-15 | Procedimiento para preparar de rivados de la (naftiridina-1,8 il-2)-2 (piperazinil-1 carboniloxi)-3 isoindolinona-1 y sus homologos mono y diazotados (naftiridina-1,8 il-2)-6 (piperazinil-1-carboniloxi)-7-oxo 5 pirrolpiridinas y (naftiridina1,8 il-2),6 (piperazinil-1 carboniloxi)-7 oxo-5 pirrolpirazinas |
| PL1974171103A PL90061B1 (en) | 1973-05-15 | 1974-05-15 | Naphthydridine[au6888074a] |
| FI1498/74A FI55659C (fi) | 1973-05-15 | 1974-05-15 | Foerfarande foer framstaellning av terapeutiskt aktiva 3-(4-substituerad-piperazin-1-ylkarbonyloxi)-2-(1,8-naftyridin-2-yl)isoindolin-1-oner |
| PL1974186640A PL94079B1 (en) | 1974-03-14 | 1974-05-15 | Manufacture of novel naphthyridine derivative [jp57150693a] [jp1194027c] |
| DE2423650A DE2423650A1 (de) | 1973-05-15 | 1974-05-15 | Neue naphtyridinderivate, deren herstellung und diese enthaltende zusammensetzungen |
| AR257458A AR210851A1 (es) | 1973-05-15 | 1975-01-29 | Procedimento para preparar nuevos derivados de la (naftiridina-1,8 il-2) 1(piperazinil)-1carboniloxi-3)-2 oxo-5 pirrolina |
| SU752112823A SU589916A3 (ru) | 1973-05-15 | 1975-03-18 | Способ получени производных нафтиридина или их солей |
| SU752114917A SU629877A3 (ru) | 1974-03-14 | 1975-03-19 | Способ получени производных нафтиридина или их солей |
| US05/623,358 US4038391A (en) | 1973-05-15 | 1975-10-17 | 6-(1,8-Naphthyridin-2-yl)-5-piperazino carbonyloxy-7-oxo-6,7-dihydro-5H-pyrrolo-[3,4-b]pyrazines and related pyridines |
| US05/623,359 US4016274A (en) | 1973-05-15 | 1975-10-17 | Naphthyridine derivatives |
| AT86676A AT336031B (de) | 1973-05-15 | 1976-02-09 | Verfahren zur herstellung von neuen naphthyridinderivaten und von deren saureadditionssalzen |
| CS766364A CS191887B2 (en) | 1973-05-15 | 1976-10-01 | Method of producing novel derivatives of naphtyridine |
| YU02877/81A YU287781A (en) | 1973-05-15 | 1981-12-08 | Process for obtaining new naphthiridine derivatives |
| YU287681A YU287681A (en) | 1974-03-14 | 1981-12-08 | Process for obtaining new naphthiridine derivatives |
| JP57024659A JPS5827279B2 (ja) | 1974-03-14 | 1982-02-19 | 新規なナフチリジン誘導体の製法 |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR7408730A FR2263752A1 (en) | 1974-03-14 | 1974-03-14 | 1,8-Naphthyridine derivs - tranquillizers and anti-convulsants |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| FR2263752A1 true FR2263752A1 (en) | 1975-10-10 |
| FR2263752B1 FR2263752B1 (online.php) | 1978-07-28 |
Family
ID=9136327
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| FR7408730A Granted FR2263752A1 (en) | 1973-05-15 | 1974-03-14 | 1,8-Naphthyridine derivs - tranquillizers and anti-convulsants |
Country Status (3)
| Country | Link |
|---|---|
| JP (1) | JPS5827279B2 (online.php) |
| FR (1) | FR2263752A1 (online.php) |
| PL (1) | PL94079B1 (online.php) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2000050424A1 (en) * | 1999-02-22 | 2000-08-31 | Biochem Pharma Inc. | [1,8] naphthyridine derivatives having antiviral activity |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS6081987U (ja) * | 1983-11-09 | 1985-06-06 | 新キャタピラ−三菱株式会社 | 建設機械用クランプ装置 |
| JPS60173587U (ja) * | 1984-04-25 | 1985-11-16 | 飯田 星祥 | ▲つか▼み機 |
| JPS618685U (ja) * | 1984-06-23 | 1986-01-18 | 正己 川名 | 重機に装着される特殊開閉装置 |
-
1974
- 1974-03-14 FR FR7408730A patent/FR2263752A1/fr active Granted
- 1974-05-15 PL PL1974186640A patent/PL94079B1/pl unknown
-
1982
- 1982-02-19 JP JP57024659A patent/JPS5827279B2/ja not_active Expired
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2000050424A1 (en) * | 1999-02-22 | 2000-08-31 | Biochem Pharma Inc. | [1,8] naphthyridine derivatives having antiviral activity |
| US6340690B1 (en) | 1999-02-22 | 2002-01-22 | Bio-Chem Pharma Inc. | Antiviral methods using [1,8]naphthyridine derivatives |
Also Published As
| Publication number | Publication date |
|---|---|
| JPS5827279B2 (ja) | 1983-06-08 |
| PL94079B1 (en) | 1977-07-30 |
| FR2263752B1 (online.php) | 1978-07-28 |
| JPS57150693A (en) | 1982-09-17 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| ST | Notification of lapse |