ES2001102A6 - Un procedimiento para la preparacion de un derivado de indeno. - Google Patents

Un procedimiento para la preparacion de un derivado de indeno.

Info

Publication number
ES2001102A6
ES2001102A6 ES8601191A ES8601191A ES2001102A6 ES 2001102 A6 ES2001102 A6 ES 2001102A6 ES 8601191 A ES8601191 A ES 8601191A ES 8601191 A ES8601191 A ES 8601191A ES 2001102 A6 ES2001102 A6 ES 2001102A6
Authority
ES
Spain
Prior art keywords
group
lower alkyl
substituted
combination
individually
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES8601191A
Other languages
English (en)
Inventor
Shozo Nakaoku
Kazuhiko Sakuma
Yasuhiro Oshika
Kazuo Ohira
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Taiyo Pharmaceutical Industry Co Ltd
Original Assignee
Taiyo Pharmaceutical Industry Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Taiyo Pharmaceutical Industry Co Ltd filed Critical Taiyo Pharmaceutical Industry Co Ltd
Publication of ES2001102A6 publication Critical patent/ES2001102A6/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
    • C07D317/44—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D317/46—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems condensed with one six-membered ring
    • C07D317/48—Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/08—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
    • C07D295/096—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms separated by carbocyclic rings or by carbon chains interrupted by carbocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
    • C07D317/44—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D317/70—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems condensed with ring systems containing two or more relevant rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D407/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00
    • C07D407/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings
    • C07D407/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

UN PROCEDIMIENTO PARA LA PREPARACION DE UN DERIVADO DE INDENO. EL COMPUESTO (I) EN QUE R1, R2, R3, R4 Y R5 REPRESENTAN VARIOS RADICALES ORGANICOS, SE PREPARA POR REACCION DEL COMPUESTO (II) CON EL COMPUESTO (III) SIENDO X UN ATOMO DE HALOGENO, AGITANDO LA MEZCLA DE REACCION A TEMPERATURA AMBIENTE O ENFRIANDO CON HIELO, EN UN DISOLVENTE. ESTOS COMPUESTOS SON UTILES COMO AGENTES TERAPEUTICOS PARA ANGINA DE PECHO Y SIMILARES.
ES8601191A 1986-02-03 1986-08-19 Un procedimiento para la preparacion de un derivado de indeno. Expired ES2001102A6 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP61021732A JPS62178552A (ja) 1986-02-03 1986-02-03 インデン類化合物

Publications (1)

Publication Number Publication Date
ES2001102A6 true ES2001102A6 (es) 1988-04-16

Family

ID=12063248

Family Applications (1)

Application Number Title Priority Date Filing Date
ES8601191A Expired ES2001102A6 (es) 1986-02-03 1986-08-19 Un procedimiento para la preparacion de un derivado de indeno.

Country Status (8)

Country Link
US (2) US4762927A (es)
EP (1) EP0235345B1 (es)
JP (1) JPS62178552A (es)
KR (1) KR940003298B1 (es)
CA (1) CA1269977A (es)
DE (1) DE3686974T2 (es)
ES (1) ES2001102A6 (es)
PT (1) PT83223B (es)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS63239220A (ja) * 1987-03-27 1988-10-05 Taiyo Yakuhin Kogyo Kk 脳循環代謝改善剤
KR100595963B1 (ko) * 2004-04-13 2006-07-05 한국화학연구원 인덴 유도체 및 이의 제조방법
KR100911143B1 (ko) 2004-10-18 2009-08-06 삼성전자주식회사 인쇄 순서 제어 방법 및 장치, 그를 이용한 인쇄장치
JP4834986B2 (ja) * 2004-12-10 2011-12-14 株式会社Ｉｈｉ 熱電ユニット

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4082773A (en) * 1972-07-03 1978-04-04 E. R. Squibb & Sons, Inc. Tricyclic tetrahydro naphthaleneols and related compounds
US4096173A (en) * 1977-03-28 1978-06-20 Eli Lilly And Company Chlorinated 1-aminoindane N-methyl transferase inhibitors
US4393226A (en) * 1981-05-06 1983-07-12 The Ohio State University Research Foundation Compounds and methods for changing calcium metabolism within the cells of a mammal
US4542153A (en) * 1981-05-06 1985-09-17 The Ohio State University Research Foundation Methods for changing calcium metabolism within the cells of a mammal
US4723022A (en) * 1986-03-10 1988-02-02 Oread Laboratories, Inc. Substituted 2,3-naphthalenedicarboxaldehydes

Also Published As

Publication number Publication date
JPS62178552A (ja) 1987-08-05
EP0235345B1 (en) 1992-10-14
KR870007908A (ko) 1987-09-22
DE3686974D1 (de) 1992-11-19
DE3686974T2 (de) 1993-03-04
US4876345A (en) 1989-10-24
EP0235345A1 (en) 1987-09-09
CA1269977A (en) 1990-06-05
US4762927A (en) 1988-08-09
KR940003298B1 (ko) 1994-04-20
PT83223A (en) 1986-09-01
PT83223B (pt) 1988-07-01

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