FR2255299B1 - - Google Patents

Info

Publication number
FR2255299B1
FR2255299B1 FR7346001A FR7346001A FR2255299B1 FR 2255299 B1 FR2255299 B1 FR 2255299B1 FR 7346001 A FR7346001 A FR 7346001A FR 7346001 A FR7346001 A FR 7346001A FR 2255299 B1 FR2255299 B1 FR 2255299B1
Authority
FR
France
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
FR7346001A
Other languages
French (fr)
Other versions
FR2255299A1 (enrdf_load_stackoverflow
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
F Hoffmann La Roche AG
Original Assignee
F Hoffmann La Roche AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by F Hoffmann La Roche AG filed Critical F Hoffmann La Roche AG
Publication of FR2255299A1 publication Critical patent/FR2255299A1/fr
Application granted granted Critical
Publication of FR2255299B1 publication Critical patent/FR2255299B1/fr
Expired legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D311/00Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/04Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
    • CCHEMISTRY; METALLURGY
    • C11ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
    • C11BPRODUCING, e.g. BY PRESSING RAW MATERIALS OR BY EXTRACTION FROM WASTE MATERIALS, REFINING OR PRESERVING FATS, FATTY SUBSTANCES, e.g. LANOLIN, FATTY OILS OR WAXES; ESSENTIAL OILS; PERFUMES
    • C11B5/00Preserving by using additives, e.g. anti-oxidants
    • C11B5/0021Preserving by using additives, e.g. anti-oxidants containing oxygen
    • C11B5/0035Phenols; Their halogenated and aminated derivates, their salts, their esters with carboxylic acids
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C17/00Preparation of halogenated hydrocarbons
    • C07C17/093Preparation of halogenated hydrocarbons by replacement by halogens
    • C07C17/16Preparation of halogenated hydrocarbons by replacement by halogens of hydroxyl groups
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C255/00Carboxylic acid nitriles
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C29/00Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring
    • C07C29/132Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring by reduction of an oxygen containing functional group
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C29/00Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring
    • C07C29/132Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring by reduction of an oxygen containing functional group
    • C07C29/136Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring by reduction of an oxygen containing functional group of >C=O containing groups, e.g. —COOH
    • C07C29/14Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring by reduction of an oxygen containing functional group of >C=O containing groups, e.g. —COOH of a —CHO group
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C29/00Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring
    • C07C29/74Separation; Purification; Use of additives, e.g. for stabilisation
    • C07C29/76Separation; Purification; Use of additives, e.g. for stabilisation by physical treatment
    • C07C29/80Separation; Purification; Use of additives, e.g. for stabilisation by physical treatment by distillation
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C59/00Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C59/40Unsaturated compounds
    • C07C59/42Unsaturated compounds containing hydroxy or O-metal groups
    • C07C59/52Unsaturated compounds containing hydroxy or O-metal groups a hydroxy or O-metal group being bound to a carbon atom of a six-membered aromatic ring
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D311/00Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/04Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
    • C07D311/58Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4
    • C07D311/70Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4 with two hydrocarbon radicals attached in position 2 and elements other than carbon and hydrogen in position 6
    • C07D311/723,4-Dihydro derivatives having in position 2 at least one methyl radical and in position 6 one oxygen atom, e.g. tocopherols
    • CCHEMISTRY; METALLURGY
    • C09DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
    • C09KMATERIALS FOR MISCELLANEOUS APPLICATIONS, NOT PROVIDED FOR ELSEWHERE
    • C09K15/00Anti-oxidant compositions; Compositions inhibiting chemical change
    • C09K15/04Anti-oxidant compositions; Compositions inhibiting chemical change containing organic compounds
    • C09K15/06Anti-oxidant compositions; Compositions inhibiting chemical change containing organic compounds containing oxygen
    • CCHEMISTRY; METALLURGY
    • C09DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
    • C09KMATERIALS FOR MISCELLANEOUS APPLICATIONS, NOT PROVIDED FOR ELSEWHERE
    • C09K15/00Anti-oxidant compositions; Compositions inhibiting chemical change
    • C09K15/04Anti-oxidant compositions; Compositions inhibiting chemical change containing organic compounds
    • C09K15/06Anti-oxidant compositions; Compositions inhibiting chemical change containing organic compounds containing oxygen
    • C09K15/08Anti-oxidant compositions; Compositions inhibiting chemical change containing organic compounds containing oxygen containing a phenol or quinone moiety
    • CCHEMISTRY; METALLURGY
    • C10PETROLEUM, GAS OR COKE INDUSTRIES; TECHNICAL GASES CONTAINING CARBON MONOXIDE; FUELS; LUBRICANTS; PEAT
    • C10MLUBRICATING COMPOSITIONS; USE OF CHEMICAL SUBSTANCES EITHER ALONE OR AS LUBRICATING INGREDIENTS IN A LUBRICATING COMPOSITION
    • C10M1/00Liquid compositions essentially based on mineral lubricating oils or fatty oils; Their use as lubricants
    • C10M1/08Liquid compositions essentially based on mineral lubricating oils or fatty oils; Their use as lubricants with additives
    • CCHEMISTRY; METALLURGY
    • C10PETROLEUM, GAS OR COKE INDUSTRIES; TECHNICAL GASES CONTAINING CARBON MONOXIDE; FUELS; LUBRICANTS; PEAT
    • C10MLUBRICATING COMPOSITIONS; USE OF CHEMICAL SUBSTANCES EITHER ALONE OR AS LUBRICATING INGREDIENTS IN A LUBRICATING COMPOSITION
    • C10M2207/00Organic non-macromolecular hydrocarbon compounds containing hydrogen, carbon and oxygen as ingredients in lubricant compositions
    • C10M2207/28Esters

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Materials Engineering (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Emergency Medicine (AREA)
  • Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Pyrane Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Edible Oils And Fats (AREA)
  • Anti-Oxidant Or Stabilizer Compositions (AREA)
  • Fats And Perfumes (AREA)
  • Food Preservation Except Freezing, Refrigeration, And Drying (AREA)
FR7346001A 1972-12-22 1973-12-21 Expired FR2255299B1 (enrdf_load_stackoverflow)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US31756672A 1972-12-22 1972-12-22

Publications (2)

Publication Number Publication Date
FR2255299A1 FR2255299A1 (enrdf_load_stackoverflow) 1975-07-18
FR2255299B1 true FR2255299B1 (enrdf_load_stackoverflow) 1977-06-10

Family

ID=23234257

Family Applications (2)

Application Number Title Priority Date Filing Date
FR7346000A Granted FR2284604A1 (fr) 1972-12-22 1973-12-21 Procede de preparation d'a-tocopherol
FR7346001A Expired FR2255299B1 (enrdf_load_stackoverflow) 1972-12-22 1973-12-21

Family Applications Before (1)

Application Number Title Priority Date Filing Date
FR7346000A Granted FR2284604A1 (fr) 1972-12-22 1973-12-21 Procede de preparation d'a-tocopherol

Country Status (21)

Country Link
JP (3) JPS4988876A (enrdf_load_stackoverflow)
KR (1) KR780000008B1 (enrdf_load_stackoverflow)
AR (1) AR200751A1 (enrdf_load_stackoverflow)
AT (1) AT333755B (enrdf_load_stackoverflow)
BE (2) BE808942A (enrdf_load_stackoverflow)
CA (1) CA1022562A (enrdf_load_stackoverflow)
CH (3) CH605892A5 (enrdf_load_stackoverflow)
DD (1) DD109624A5 (enrdf_load_stackoverflow)
DE (2) DE2364165A1 (enrdf_load_stackoverflow)
ES (1) ES421683A1 (enrdf_load_stackoverflow)
FR (2) FR2284604A1 (enrdf_load_stackoverflow)
GB (4) GB1456830A (enrdf_load_stackoverflow)
HU (1) HU168043B (enrdf_load_stackoverflow)
IE (1) IE38671B1 (enrdf_load_stackoverflow)
IL (1) IL43888A (enrdf_load_stackoverflow)
LU (1) LU69067A1 (enrdf_load_stackoverflow)
NL (2) NL178968C (enrdf_load_stackoverflow)
PH (1) PH11133A (enrdf_load_stackoverflow)
SE (1) SE406912B (enrdf_load_stackoverflow)
SU (1) SU518135A3 (enrdf_load_stackoverflow)
ZA (1) ZA739471B (enrdf_load_stackoverflow)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH618695A5 (en) * 1975-01-27 1980-08-15 Hoffmann La Roche Process for the preparation of chromane derivatives
NL7805217A (nl) * 1977-05-16 1978-11-20 Hoffmann La Roche Werkwijze voor de bereiding van tussenverbindingen voor de bereiding van vitamine e.
US4150050A (en) * 1978-01-30 1979-04-17 Hoffmann-La Roche Inc. 3,6-Dioxo-1,4-cyclohexadien-1-yl-butandate esters
EP0003484B1 (de) * 1978-01-30 1981-10-14 F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft Verfahren zur Herstellung von Chromanderivaten
DE2909601A1 (de) * 1979-03-12 1980-09-25 Basf Ag Verfahren zur herstellung von chromanderivaten
DE3010505A1 (de) * 1980-03-19 1981-10-01 Basf Ag, 6700 Ludwigshafen Chromanderivate, verfahren zu ihrer herstellung, ihre verwendung als stabilisatoren von organischen materialien sowie diese stabilisatoren enthaltende organische materialien
DE3010504A1 (de) * 1980-03-19 1981-10-01 Basf Ag, 6700 Ludwigshafen Verfahren zur herstellung von 2-hydroxyalkylchromanen
DE3103707A1 (de) * 1981-02-04 1982-08-19 Basf Ag, 6700 Ludwigshafen Chromanderivate
DE3103740A1 (de) * 1981-02-04 1982-08-19 Basf Ag, 6700 Ludwigshafen Chromanderivate
JPS57136582A (en) * 1981-02-19 1982-08-23 Eisai Co Ltd Preparation of optically active alpha-tocopherol
JPS57145871A (en) * 1981-03-05 1982-09-09 Eisai Co Ltd Chromanolcarboxylic derivative
DE3139238A1 (de) * 1981-10-02 1983-04-21 Basf Ag, 6700 Ludwigshafen Optisch aktive bausteine fuer die synthese der seitenkette von (r,r,r)-(alpha)-tocopherol sowie verfahren zu deren herstellung
DE3367391D1 (en) * 1982-12-23 1986-12-11 Ici America Inc Chroman compounds
ZA844519B (en) * 1983-06-24 1985-02-27 Hoffmann La Roche Dihydrobenzopyran derivatives
DE3760058D1 (en) * 1986-01-23 1989-04-13 Hoffmann La Roche 3,4-dihydro-2,5,7,8-tetramethyl-2h-1-benzopyran derivatives and processes for their preparation
US4987231A (en) * 1989-08-04 1991-01-22 Pfizer Inc. Optical resolution method for 3R-(3-carboxybenzyl)-6-(5-fluoro-2-benzothiazolyl)methoxy-4R-chromanol
CA2082004A1 (en) * 1991-11-20 1993-05-21 David Laffan Substituted pentaalkylchromans
DE19859251A1 (de) * 1998-12-22 2000-06-29 Basf Ag Verfahren zur Herstellung von substituierten Chromanderivaten
WO2002012221A1 (fr) * 2000-08-03 2002-02-14 Kuraray Co., Ltd. Procede de resolution optique de l'acide (±)-6-hydroxy-2,5,7,8,-tetramethyle de coumarone-2-carboxylique
JP4904816B2 (ja) * 2004-01-30 2012-03-28 三菱瓦斯化学株式会社 クロマン化合物の製造方法
KR101233223B1 (ko) * 2004-12-21 2013-02-14 제이엔씨 석유 화학 주식회사 크로만환을 가지는 액정 화합물, 액정 조성물 및 이 액정조성물을 함유하는 액정 표시소자
EP2522647B1 (en) * 2011-05-10 2014-04-30 DSM IP Assets B.V. Process of separating chiral isomers of chroman compounds and their derivatives and precursors
NL2010010C2 (en) 2012-12-19 2014-06-23 Sulfateq B V Compounds for protection of cells.
IL295785A (en) * 2020-02-21 2022-10-01 Sumitomo Pharma Co Ltd An optically degradable trolox intermediate and a method for its production

Also Published As

Publication number Publication date
JPS6026795B2 (ja) 1985-06-25
JPS59144780A (ja) 1984-08-18
IL43888A0 (en) 1974-03-14
DD109624A5 (enrdf_load_stackoverflow) 1974-11-12
DE2364141A1 (de) 1974-06-27
CH622257A5 (en) 1981-03-31
GB1456827A (en) 1976-11-24
JPS5946233B2 (ja) 1984-11-10
PH11133A (en) 1977-10-27
NL7317587A (enrdf_load_stackoverflow) 1974-06-25
BE808942A (fr) 1974-06-21
FR2284604A1 (fr) 1976-04-09
ZA739471B (en) 1974-08-28
GB1456829A (en) 1976-11-24
GB1456828A (en) 1976-11-24
JPS4988877A (enrdf_load_stackoverflow) 1974-08-24
ATA1076973A (de) 1976-04-15
AR200751A1 (es) 1974-12-13
FR2255299A1 (enrdf_load_stackoverflow) 1975-07-18
KR780000008B1 (en) 1978-03-04
NL178968C (nl) 1986-06-16
BE808943A (fr) 1974-06-21
IE38671B1 (en) 1978-05-10
CH603617A5 (enrdf_load_stackoverflow) 1978-08-31
DE2364165A1 (de) 1974-06-27
IL43888A (en) 1977-02-28
HU168043B (enrdf_load_stackoverflow) 1976-02-28
SU518135A3 (ru) 1976-06-15
IE38671L (en) 1974-06-22
JPS4988876A (enrdf_load_stackoverflow) 1974-08-24
SE406912B (sv) 1979-03-05
LU69067A1 (enrdf_load_stackoverflow) 1975-08-20
NL7317590A (enrdf_load_stackoverflow) 1974-06-25
CH605892A5 (enrdf_load_stackoverflow) 1978-10-13
AT333755B (de) 1976-12-10
GB1456830A (en) 1976-11-24
ES421683A1 (es) 1976-04-01
FR2284604B1 (enrdf_load_stackoverflow) 1979-05-11
CA1022562A (en) 1977-12-13
AU6400973A (en) 1975-07-03

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Legal Events

Date Code Title Description
ST Notification of lapse