FR2137899A1 - - Google Patents

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Publication number
FR2137899A1
FR2137899A1 FR7217283A FR7217283A FR2137899A1 FR 2137899 A1 FR2137899 A1 FR 2137899A1 FR 7217283 A FR7217283 A FR 7217283A FR 7217283 A FR7217283 A FR 7217283A FR 2137899 A1 FR2137899 A1 FR 2137899A1
Authority
FR
France
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7217283A
Other languages
French (fr)
Other versions
FR2137899B1 (pt
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Glaxo Laboratories Ltd
Original Assignee
Glaxo Laboratories Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=26251025&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=FR2137899(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Glaxo Laboratories Ltd filed Critical Glaxo Laboratories Ltd
Publication of FR2137899A1 publication Critical patent/FR2137899A1/fr
Application granted granted Critical
Publication of FR2137899B1 publication Critical patent/FR2137899B1/fr
Expired legal-status Critical Current

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/34—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D307/38—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D307/40—Radicals substituted by oxygen atoms
    • C07D307/42—Singly bound oxygen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C271/00—Derivatives of carbamic acids, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups
    • C07C271/06—Esters of carbamic acids
    • C07C271/08—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms
    • C07C271/10—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms
    • C07C271/14—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms to carbon atoms of hydrocarbon radicals substituted by halogen atoms or by nitro or nitroso groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D213/54—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/55—Acids; Esters
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/34—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D307/38—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D307/54—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/78—Benzo [b] furans; Hydrogenated benzo [b] furans
    • C07D307/79—Benzo [b] furans; Hydrogenated benzo [b] furans with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/78—Benzo [b] furans; Hydrogenated benzo [b] furans
    • C07D307/79—Benzo [b] furans; Hydrogenated benzo [b] furans with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
    • C07D307/81—Radicals substituted by nitrogen atoms not forming part of a nitro radical
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
    • C07D333/06—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring carbon atoms
    • C07D333/14—Radicals substituted by singly bound hetero atoms other than halogen
    • C07D333/16—Radicals substituted by singly bound hetero atoms other than halogen by oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
    • C07D333/06—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring carbon atoms
    • C07D333/24—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/50—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D333/52—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes
    • C07D333/54—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
    • C07D333/60—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D499/00—Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Communicable Diseases (AREA)
  • Animal Behavior & Ethology (AREA)
  • Oncology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Cephalosporin Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Compounds Containing Sulfur Atoms (AREA)
  • Furan Compounds (AREA)
  • Pyridine Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
FR7217283A 1971-05-14 1972-05-15 Expired FR2137899B1 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB1508271A GB1399086A (en) 1971-05-14 1971-05-14 Cephalosporin compounds
GB4588471 1971-10-01

Publications (2)

Publication Number Publication Date
FR2137899A1 true FR2137899A1 (pt) 1972-12-29
FR2137899B1 FR2137899B1 (pt) 1976-08-20

Family

ID=26251025

Family Applications (2)

Application Number Title Priority Date Filing Date
FR7217284A Expired FR2137900B1 (pt) 1971-05-14 1972-05-15
FR7217283A Expired FR2137899B1 (pt) 1971-05-14 1972-05-15

Family Applications Before (1)

Application Number Title Priority Date Filing Date
FR7217284A Expired FR2137900B1 (pt) 1971-05-14 1972-05-15

Country Status (22)

Country Link
JP (3) JPS531280B1 (pt)
AT (1) AT336786B (pt)
BE (1) BE783449A (pt)
CA (1) CA1027554A (pt)
CH (1) CH591497A5 (pt)
CS (2) CS245754B2 (pt)
CY (1) CY971A (pt)
DE (2) DE2223375C2 (pt)
DK (1) DK155187C (pt)
ES (2) ES402651A1 (pt)
FR (2) FR2137900B1 (pt)
GB (1) GB1399086A (pt)
HK (1) HK66078A (pt)
IE (1) IE38172B1 (pt)
IL (1) IL39429A (pt)
KE (1) KE2895A (pt)
MY (1) MY7800466A (pt)
NL (1) NL166688C (pt)
NO (1) NO154797C (pt)
PH (1) PH11205A (pt)
SE (1) SE457795B (pt)
YU (2) YU41807B (pt)

Cited By (54)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2204403A2 (pt) * 1972-10-25 1974-05-24 Glaxo Lab Ltd
FR2282275A1 (fr) * 1974-08-23 1976-03-19 Glaxo Lab Ltd Perfectionnements relatifs aux antibiotiques
FR2348218A1 (fr) * 1976-04-14 1977-11-10 Takeda Chemical Industries Ltd Nouveaux derives cephalosporines ayant un nouveau groupe 7-acyle et leur procede de fabrication
FR2348219A1 (fr) * 1976-04-12 1977-11-10 Fujisawa Pharmaceutical Co Procede de preparation d'isomeres syn de composes d'acides 3,7-cephem-4-carboxyliques 3,7-disubstitues et nouveaux produits ainsi obtenus, a activite antibacterienne
FR2361895A1 (fr) * 1976-08-20 1978-03-17 Roussel Uclaf Nouvelles oximes derivees de l'acide 3-carbamoyloxymethyl 7-amino thiazolyl acetamido cephalosporanique, leur procede de preparation et leur application comme medicaments
FR2381053A1 (fr) * 1977-02-18 1978-09-15 Roussel Uclaf Nouvelles oximes derivees de l'acide 3-thiadiazolyl thiomethyl 7-aminothiazolyl acetamido cephalosporanique, leur procede de preparation et leur application comme medicaments
FR2381052A1 (fr) * 1977-02-18 1978-09-15 Takeda Chemical Industries Ltd Derives de cephalosporine, leur procede de preparation et leur utilisation
FR2384779A1 (fr) * 1977-03-25 1978-10-20 Roussel Uclaf Nouvelles oximes derivees de l'acide 3-chloro ou 3-methoxy 7-amino thiazolyl acetamido cephalosporanique, leur procede de preparation et leur application comme medicaments
FR2385722A1 (fr) * 1977-04-02 1978-10-27 Hoechst Ag Nouveaux derives de cephalosporine, leur procede de preparation et leur application en therapeutique
FR2387234A1 (fr) * 1977-04-15 1978-11-10 Hoechst Ag Derives de cephalosporine, leur procede de preparation et leurs applications en therapeutique
EP0000005A1 (de) * 1977-06-03 1978-12-20 F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft Neue Cephalosporinderivate, Verfahren zu ihrer Herstellung und pharmazeutische Präparate
FR2411839A1 (fr) * 1977-11-14 1979-07-13 Fujisawa Pharmaceutical Co Derives de l'acide cephalosporanique, procedes pour leur preparation et composition pharmaceutique les contenant
FR2438051A2 (fr) * 1978-10-05 1980-04-30 Roussel Uclaf Nouvelles oximes derivees de l'acide 3-azidomethyl 7-amino thiazolyl acetamido cephalosporanique, leur procede de preparation et leur application comme medicaments
EP0025199A2 (en) * 1979-09-03 1981-03-18 Fujisawa Pharmaceutical Co., Ltd. Cephem compounds, processes for their preparation and pharmaceutical compositions containing them
EP0027599A2 (en) * 1979-10-12 1981-04-29 Fujisawa Pharmaceutical Co., Ltd. Cephem compounds, processes for their preparation and pharmaceutical compositions containing them
EP0034536A2 (fr) * 1980-02-18 1981-08-26 Roussel-Uclaf Nouvelles oximes dérivées de l'acide 3-alkyloxy ou 3-alkylthiométhyl 7-amino thiazolylacétamido céphalosporanique, leur préparation, leur application comme médicaments et les compositions les renfermant
EP0037797A2 (de) * 1980-03-11 1981-10-14 Ciba-Geigy Ag Cephalosporinverbindungen, Verfahren zu ihrer Herstellung, sie enthaltende pharmazeutische Zusammensetzungen und ihre Verwendung
EP0042154A1 (en) * 1980-06-18 1981-12-23 Fujisawa Pharmaceutical Co., Ltd. New cephem compounds and processes for preparation thereof
EP0045937A2 (en) * 1980-08-11 1982-02-17 Fujisawa Pharmaceutical Co., Ltd. New cephem compounds and processes for preparation thereof
EP0046964A2 (en) * 1980-08-29 1982-03-10 Fujisawa Pharmaceutical Co., Ltd. New cephem compounds and processes for preparation thereof
EP0047491A2 (en) * 1980-09-08 1982-03-17 Fujisawa Pharmaceutical Co., Ltd. New cephem compounds and processes for preparation thereof
EP0049855A2 (de) * 1980-10-10 1982-04-21 F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft Neue Cephalosporinderivate, Verfahren zu ihrer Herstellung und Zwischenprodukte dafür sowie entsprechende pharmazeutische Präparate
FR2494279A1 (fr) * 1980-11-20 1982-05-21 Rhone Poulenc Ind Nouvelles oxacephalosporines, leur preparation et les medicaments qui les contiennent
EP0053074A1 (fr) * 1980-11-20 1982-06-02 Rhone-Poulenc Sante Nouveaux dérivés de la céphalosporine et leur préparation
EP0053538A2 (fr) * 1980-11-20 1982-06-09 Rhone-Poulenc Sante Nouvelles vinyl-3 céphalosporines et leur préparation
EP0053537A1 (fr) * 1980-11-20 1982-06-09 Rhone-Poulenc Sante Nouveaux dérivés de vinyl-3 céphalosporines et leur préparation
EP0053961A1 (fr) * 1980-11-20 1982-06-16 Rhone-Poulenc Sante Nouvelles thiovinyl-3 céphalosporines, leur préparation et les compositions pharmaceutiques qui les contiennent
EP0057422A2 (en) * 1981-02-02 1982-08-11 Fujisawa Pharmaceutical Co., Ltd. New cephem compounds, processes for preparation thereof and pharmaceutical composition containing them
FR2499995A1 (fr) * 1981-02-13 1982-08-20 Roussel Uclaf Nouvelles oximes derivees de l'acide 3-alkyloxy ou 3-alkylthiomethyl 7-amino thiazolylacetamido cephalosporanique, leur preparation, leur application comme medicaments, les compositions les renfermant et les nouveaux intermediaires obtenus.
FR2503712A1 (fr) * 1981-04-09 1982-10-15 Yamanouchi Pharma Co Ltd Composes de la cephalosporine et procede pour leur preparation
FR2505338A1 (fr) * 1981-05-11 1982-11-12 Rhone Poulenc Sante Nouvelles oxacephalosporines et leur preparation
FR2505339A1 (fr) * 1981-05-11 1982-11-12 Rhone Poulenc Sante Nouvelles oxacephalosporines et leur preparation
FR2509310A1 (fr) * 1980-09-25 1983-01-14 Toyama Chemical Co Ltd Nouvelles cephalosporines, leur procede de preparation et leur application en therapeutique
EP0070803A2 (de) * 1981-07-16 1983-01-26 Ciba-Geigy Ag Antibiotisch wirksame Aminotriazolyl-Cephalosporinderivate und ihre Herstellung
EP0074268A2 (en) * 1981-09-08 1983-03-16 Eli Lilly And Company Improvements in or relating to thieno and furopyridinium-substituted cephalosporin derivatives
FR2514005A1 (fr) * 1981-10-02 1983-04-08 Lilly Co Eli Cephalosporines a substitution pyrazinium
EP0076452A2 (de) * 1981-09-30 1983-04-13 Ciba-Geigy Ag Cephalosporinverbindungen, Verfahren zu ihrer Herstellung und sie enthaltende pharmazeutische Präparate
EP0076528A2 (fr) * 1980-02-18 1983-04-13 Roussel-Uclaf Nouvelles oximes dérivées de l'acide 3-alkyloxy ou 3-alkylthiométhyl 7-amino thiazolylacétamido céphalosporanique et leur préparation
EP0091130A2 (en) * 1982-04-06 1983-10-12 Daiichi Seiyaku Co., Ltd. Cephalosporin derivatives, process for preparing and pharmaceutical compositions containing said compounds
FR2530635A1 (fr) * 1982-07-23 1984-01-27 Servipharm Ltd Composes d'amino-imidazolyle, procede pour leur preparation, preparations pharmaceutiques contenant ces composes, et application de ces dernieres
EP0101265A2 (en) * 1982-08-07 1984-02-22 Tanabe Seiyaku Co., Ltd. Novel cephalosporin compounds and preparation thereof
EP0103264A2 (en) * 1982-09-10 1984-03-21 Fujisawa Pharmaceutical Co., Ltd. New cephem compounds and processes for preparation thereof
FR2533216A1 (fr) * 1982-09-22 1984-03-23 Toyama Chemical Co Ltd Nouvelles cephalosporines, et leurs sels
EP0097961A3 (en) * 1982-06-28 1984-10-03 Bristol-Myers Company Cephalosporin derivatives, a process for the manufacture thereof and pharmaceutical compositions containing said derivatives
EP0122157A2 (en) * 1983-04-12 1984-10-17 Eli Lilly And Company Improvements in or relating to indolylglycyl cephalosporin derivatives
EP0122155A2 (en) * 1983-04-12 1984-10-17 Eli Lilly And Company Improvements in or relating to naphthylglycyl cephalosporin derivatives
EP0122156A2 (en) * 1983-04-12 1984-10-17 Eli Lilly And Company Improvements in or relating to benzothienylglycyl cephalosporin derivatives
EP0122154A2 (en) * 1983-04-12 1984-10-17 Eli Lilly And Company Improvements in or relating to benzothienylglycyl cephalosporin derivatives
EP0135142A2 (de) * 1983-08-25 1985-03-27 Hoechst Aktiengesellschaft Cephalosporinderivate und Verfahren zu ihrer Herstellung
US4521413A (en) * 1981-09-14 1985-06-04 Fujisawa Pharmaceutical Co., Ltd. Cephem compounds
EP0147181A2 (en) * 1983-12-21 1985-07-03 Tanabe Seiyaku Co., Ltd. Thiazolylacetic acid derivatives and their preparation
FR2564095A1 (fr) * 1984-05-10 1985-11-15 Glaxo Group Ltd Antibiotiques de cephalosporine, leur preparation et compositions pharmaceutiques les contenant
EP0175610A2 (en) * 1984-09-07 1986-03-26 Meiji Seika Kaisha Ltd. New cephalosporin compounds and the production thereof
EP0186586A2 (en) * 1984-12-20 1986-07-02 Meiji Seika Kaisha Ltd. Cephem compounds and the production thereof

Families Citing this family (70)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4033950A (en) * 1971-05-14 1977-07-05 Glaxo Laboratories Limited 3-Hydroxymethyl-7β-(2-alkoxy-or benzyloxyimino-2-arylacetamido)ceph-3-em-4-carboxylic acids and salts thereof
US4138555A (en) 1971-05-14 1979-02-06 Glaxo Laboratories, Limited (6R,7R)-7-[2-aryl-2-(etherified oximino)acetamido]-3-carbamoyloxymethylceph-3-em-4-carboxylic acid 1-oxides
GB1399086A (en) * 1971-05-14 1975-06-25 Glaxo Lab Ltd Cephalosporin compounds
US4064346A (en) * 1971-05-14 1977-12-20 Glaxo Laboratories Limited 3-Acetoxymethyl-7β-(2-carboxy-methoxyimino-2-arylacetamido)ceph-3-em-4-carboxylic acids and salts thereof
US4079178A (en) * 1971-05-14 1978-03-14 Glaxo Laboratories Limited Cephalosporins having (α-etherified oximino) acylamido groups at the 7-position
AR207341A1 (es) * 1973-03-15 1976-09-30 Fujisawa Pharmaceutical Co Un procedimiento para la preparacion de derivados de acido 2-alquil-2 o 3-cefem-4-carboxilico
US4144392A (en) 1973-12-21 1979-03-13 Glaxo Laboratories Limited Cephalosporins having at position-7 a carboxy substituted α-etherified hydroxyimino-arylacetamido group and at position-3 the residue of a sulphur nucleophile
US4144393A (en) 1973-12-21 1979-03-13 Glaxo Laboratories Limited 3-Acetoxymethyl cephalosporins having at position-7 a carboxy substituted α-etherified hydroxyiminoarylacetamido group
DK674674A (pt) * 1973-12-21 1975-09-08 Glaxo Lab Ltd
DK154939C (da) * 1974-12-19 1989-06-12 Takeda Chemical Industries Ltd Analogifremgangsmaade til fremstilling af thiazolylacetamido-cephemforbindelser eller farmaceutisk acceptable salte eller estere deraf
GB1522140A (en) * 1974-12-20 1978-08-23 Glaxo Lab Ltd Syn-7-(2-hydroxyiminoacetamido)-3-pyridiniummethyl cephalosporins methods for their preparation and compositions containing them
US4200746A (en) 1974-12-20 1980-04-29 Glaxo Laboratories, Ltd. Cephalosporins
OA05233A (fr) * 1975-02-04 1981-02-28 Fujisawa Pharmaceutical Co Procédé de préparation d'acides (7-acétamido Disubstitue)-3- substitue-3- cephem-4-carboxyliques et nouveaux produits industriels.
GB1555471A (en) * 1975-06-19 1979-11-14 Glaxo Lab Ltd 7 carbamoylalkoxyimino acetamido 3 em 4 carboxylic acidsand derivatives thereof
DE2760123C2 (de) 1976-01-23 1986-04-30 Roussel-Uclaf, Paris 7-Aminothiazolyl-syn-oxyiminoacetamidocephalosporansäuren, ihre Herstellung und sie enthaltende pharmazeutische Zusammensetzungen
SE440655B (sv) * 1976-01-23 1985-08-12 Roussel Uclaf Sett att framstella nya oximderivat av 7-amino-tiazolyl-acetamido-cefalosporansyra
IE44888B1 (en) * 1976-03-09 1982-05-05 Fujisawa Pharmaceutical Co 3,7-disubstituted-3-cephem-4-carboxylic acid compounds and processes for the preparation theroef
GB1575803A (en) 1976-03-09 1980-10-01 Fujisawa Pharmaceutical Co 3,7 disubstituted 3 cephem 4 carboxylic acid compounds andprocesses for the preparation thereof
US4165430A (en) 1976-03-19 1979-08-21 Glaxo Laboratories Limited Cephalosporins having a 7-carboxy substituted α-etherified oximinoarylacetamido) group
FR2345153A1 (fr) * 1976-03-25 1977-10-21 Roussel Uclaf Nouvelles alcoyloximes derivees de l'acide 7-amino thiazolyl acetamido cephalosporanique, leur procede de preparation et leur application comme medicaments
US4166115A (en) * 1976-04-12 1979-08-28 Fujisawa Pharmaceutical Co., Ltd. Syn 7-oxoimino substituted derivatives of cephalosporanic acid
US4278670A (en) * 1976-07-12 1981-07-14 Smithkline Corporation 7-Alpha-oxyiminoacylcephalosporins
US4066762A (en) * 1976-07-12 1978-01-03 Smithkline Corporation Derivatives of 7-(2-substituted-2-hydroxyiminoacetamido)-3-(1-substituted tetrazol-5-ylthiomethyl-3-cephem-4-carboxylic acid
GB1592149A (en) * 1976-10-08 1981-07-01 Fujisawa Pharmaceutical Co 3 7-disubstituted-3-cephem-4-carboxylic acid compounds and processes for preparation thereof
PH17188A (en) 1977-03-14 1984-06-14 Fujisawa Pharmaceutical Co New cephem and cepham compounds and their pharmaceutical compositions and method of use
SE439312B (sv) * 1977-03-25 1985-06-10 Roussel Uclaf Sett att framstella nya oximderivat av 3-acetoximetyl-7-aminotiazolylacetamido cefalosporansyra
SE445350B (sv) * 1978-04-14 1986-06-16 Roussel Uclaf Oximderivat av 3-azidometyl-7-amino-tiazolyl-acetamido-cefalosporansyra och dess anvendning som antibiotika
AR228726A1 (es) 1978-05-26 1983-04-15 Glaxo Group Ltd Procedimiento para la preparacion del antibiotico(6r,7r)-7-((z)-2-(2-aminotiazol-4-il)-2-(2-carboxiprop-2-oxiimino)acetamido)-3-(1-piridiniometil)cef-3-em-4-carboxilato
DE2822860A1 (de) * 1978-05-26 1979-11-29 Hoechst Ag Cephemderivate und verfahren zu ihrer herstellung
DE2822861A1 (de) * 1978-05-26 1979-11-29 Hoechst Ag Cephemderivate und verfahren zu ihrer herstellung
US4268509A (en) * 1978-07-10 1981-05-19 Fujisawa Pharmaceutical Co., Ltd. New cephem compounds and processes for preparation thereof
US4284631A (en) * 1978-07-31 1981-08-18 Fujisawa Pharmaceutical Co., Ltd. 7-Substituted cephem compounds and pharmaceutical antibacterial compositions containing them
LU81884A1 (fr) * 1978-11-15 1980-06-05 Glaxo Group Ltd Cephalosporines a activite antibiotique et procede de preparation
DE2914327A1 (de) * 1979-04-09 1980-10-30 Hoechst Ag Cephemderivate und verfahren zu ihrer herstellung
US4341777A (en) * 1979-09-10 1982-07-27 Glaxo Group Limited Cephalosporin antibiotic
ZA813787B (en) * 1980-06-18 1982-07-28 Fujisawa Pharmaceutical Co New cephem compounds and processes for preparation thereof
IL63207A (en) * 1980-07-24 1985-09-29 Lonza Ag Process for the preparation of 2-(2-aminothiazole-4-yl)-2-(syn)-methoxyiminoacetic acid esters
JPS5859992A (ja) * 1981-09-14 1983-04-09 Fujisawa Pharmaceut Co Ltd 新規セフエム化合物およびその製造法、並びに細菌感染症予防・治療剤
US4394503A (en) 1981-12-07 1983-07-19 Bristol-Myers Company Cephalosporin derivatives
US4474954A (en) * 1981-12-07 1984-10-02 Bristol-Myers Company Intermediates for cephalosporin derivatives
US4406899A (en) 1982-03-04 1983-09-27 Bristol-Myers Company Cephalosporins
US4457929A (en) * 1982-03-29 1984-07-03 Bristol-Myers Company 3-Quaternary ammonium methyl)-substituted cephalosporin derivatives
US4500526A (en) * 1982-06-28 1985-02-19 Bristol-Myers Company Cephalosporin derivatives
JPS5973043A (ja) * 1982-10-19 1984-04-25 House Food Ind Co Ltd 易溶性ゲル化剤の製造法
US4486586A (en) * 1983-02-10 1984-12-04 Bristol-Myers Company Cephalosporin derivatives
US4525473A (en) * 1983-03-30 1985-06-25 Bristol-Myers Company Cephalosporins
JPS60190783A (ja) * 1983-12-21 1985-09-28 Sumitomo Seiyaku Kk セフエム系化合物
DE150507T1 (de) * 1983-12-29 1987-02-26 Mochida Pharmaceutical Co., Ltd., Tokio/Tokyo Cephalosporinverbindungen, verfahren zu ihrer herstellung und pharmazeutishe praeparate.
JPS60142987A (ja) * 1983-12-29 1985-07-29 Mochida Pharmaceut Co Ltd セフアロスポリン誘導体
FI851934L (fi) * 1984-05-30 1985-12-01 Ici Plc Kefalosporinderivat.
US4868173A (en) * 1984-11-20 1989-09-19 Ici Pharma Cephalosporin derivatives
DE3587997D1 (de) * 1984-12-27 1995-04-06 Banyu Pharma Co Ltd Isoindolinderivate.
US4840945A (en) * 1985-04-01 1989-06-20 Mochida Pharmaceutical Co., Ltd. Cephalosporin derivatives
US4874856A (en) * 1985-06-24 1989-10-17 Bristol-Myers Company 3-(substituted)propenyl-7-(aminothiazolylacetamido) ceph-3-em-4-carboxylic acids and esters thereof
US4708955A (en) * 1985-06-24 1987-11-24 Bristol-Myers Company 3-(substituted)propenyl-7-aminothiazol-ylcephalosporanic acids and esters thereof
US4814328A (en) * 1986-03-19 1989-03-21 Banyu Pharmaceutical Co., Ltd. Cephalosporin derivatives, and antibacterial agents
DE3623921A1 (de) * 1986-07-16 1988-01-21 Basf Ag Oximether und diese enthaltende fungizide
ZA877987B (en) * 1986-11-12 1988-08-31 Ici Pharma Antibiotic compounds
US4880798A (en) * 1986-11-25 1989-11-14 Mochida Pharmaceutical Co., Ltd. Cephalosporin derivatives
JPS63132893A (ja) * 1986-11-25 1988-06-04 Mochida Pharmaceut Co Ltd 新規セフアロスポリン誘導体、その製法およびそれらを有効成分とする抗菌剤
EP0272827A3 (en) * 1986-12-23 1990-02-07 ZENECA Pharma S.A. 3-heterocyclicthiomethyl cephalosphorins
US5262410A (en) * 1986-12-23 1993-11-16 Ici Pharma 3-heterocyclic thiomethyl cephalosporins
US5189157A (en) * 1987-06-16 1993-02-23 Hoffmann La Roche Inc. Antibacterial cephalosporin compounds
ATE130299T1 (de) * 1987-07-23 1995-12-15 Zeneca Pharma Sa Cephalosporinverbindungen, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische präparate.
DE3854804T2 (de) * 1987-07-23 1996-06-13 Zeneca Pharma Sa Cephalosporinverbindungen, Verfahren zu ihrer Herstellung und diese enthaltende pharmazeutische Präparate
KR900006811B1 (ko) * 1988-05-11 1990-09-21 주식회사 럭 키 신규 세팔로스포린 유도체 및 그의 제조방법
US5202315A (en) * 1989-05-11 1993-04-13 Lucky, Ltd. Cephalosporin compounds
GB8927871D0 (en) * 1989-12-08 1990-02-14 Beecham Group Plc Novel compounds
IN189046B (pt) 1998-03-30 2002-12-14 Ranbaxy Lab Ltd
AU2820700A (en) * 1999-03-09 2000-09-28 Ranbaxy Laboratories Limited Process for the preparation of cefuroxime

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1073530A (en) * 1962-12-14 1967-06-28 Astra Apotekarnes Kem Fab Process for the preparation of cephalosporins
FR1556823A (pt) * 1967-03-23 1969-02-07
FR1556822A (pt) * 1967-03-23 1969-02-07

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1241657A (en) * 1967-08-21 1971-08-04 Glaxo Lab Ltd Improvements in or relating to cephalosporin compounds
GB1279402A (en) * 1968-06-14 1972-06-28 Glaxo Lab Ltd Improvements in or relating to cephalosporin derivatives
US3641021A (en) * 1969-04-18 1972-02-08 Lilly Co Eli 3 7-(ring-substituted) cephalosporin compounds
ZA72568B (en) * 1971-01-29 1972-10-25 Glaxo Lab Ltd Improvements in or relating to antibiotics
GB1399086A (en) * 1971-05-14 1975-06-25 Glaxo Lab Ltd Cephalosporin compounds

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1073530A (en) * 1962-12-14 1967-06-28 Astra Apotekarnes Kem Fab Process for the preparation of cephalosporins
FR1556823A (pt) * 1967-03-23 1969-02-07
FR1556822A (pt) * 1967-03-23 1969-02-07

Cited By (93)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2204403A2 (pt) * 1972-10-25 1974-05-24 Glaxo Lab Ltd
FR2282275A1 (fr) * 1974-08-23 1976-03-19 Glaxo Lab Ltd Perfectionnements relatifs aux antibiotiques
FR2348219A1 (fr) * 1976-04-12 1977-11-10 Fujisawa Pharmaceutical Co Procede de preparation d'isomeres syn de composes d'acides 3,7-cephem-4-carboxyliques 3,7-disubstitues et nouveaux produits ainsi obtenus, a activite antibacterienne
FR2348218A1 (fr) * 1976-04-14 1977-11-10 Takeda Chemical Industries Ltd Nouveaux derives cephalosporines ayant un nouveau groupe 7-acyle et leur procede de fabrication
FR2361895A1 (fr) * 1976-08-20 1978-03-17 Roussel Uclaf Nouvelles oximes derivees de l'acide 3-carbamoyloxymethyl 7-amino thiazolyl acetamido cephalosporanique, leur procede de preparation et leur application comme medicaments
FR2381052A1 (fr) * 1977-02-18 1978-09-15 Takeda Chemical Industries Ltd Derives de cephalosporine, leur procede de preparation et leur utilisation
FR2381053A1 (fr) * 1977-02-18 1978-09-15 Roussel Uclaf Nouvelles oximes derivees de l'acide 3-thiadiazolyl thiomethyl 7-aminothiazolyl acetamido cephalosporanique, leur procede de preparation et leur application comme medicaments
FR2384779A1 (fr) * 1977-03-25 1978-10-20 Roussel Uclaf Nouvelles oximes derivees de l'acide 3-chloro ou 3-methoxy 7-amino thiazolyl acetamido cephalosporanique, leur procede de preparation et leur application comme medicaments
FR2385722A1 (fr) * 1977-04-02 1978-10-27 Hoechst Ag Nouveaux derives de cephalosporine, leur procede de preparation et leur application en therapeutique
FR2485018A1 (fr) * 1977-04-02 1981-12-24 Hoechst Ag Nouveaux derives de cephalosporine et leur application en therapeutique
FR2485017A1 (fr) * 1977-04-02 1981-12-24 Hoechst Ag Nouveaux derives de cephalosporine et leur application en therapeutique
FR2387234A1 (fr) * 1977-04-15 1978-11-10 Hoechst Ag Derives de cephalosporine, leur procede de preparation et leurs applications en therapeutique
EP0000005A1 (de) * 1977-06-03 1978-12-20 F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft Neue Cephalosporinderivate, Verfahren zu ihrer Herstellung und pharmazeutische Präparate
FR2411839A1 (fr) * 1977-11-14 1979-07-13 Fujisawa Pharmaceutical Co Derives de l'acide cephalosporanique, procedes pour leur preparation et composition pharmaceutique les contenant
FR2438051A2 (fr) * 1978-10-05 1980-04-30 Roussel Uclaf Nouvelles oximes derivees de l'acide 3-azidomethyl 7-amino thiazolyl acetamido cephalosporanique, leur procede de preparation et leur application comme medicaments
EP0025199A2 (en) * 1979-09-03 1981-03-18 Fujisawa Pharmaceutical Co., Ltd. Cephem compounds, processes for their preparation and pharmaceutical compositions containing them
EP0025199A3 (en) * 1979-09-03 1981-05-13 Fujisawa Pharmaceutical Co. Ltd. Cephem compounds, processes for their preparation, pharmaceutical compositions containing them; intermediates and their preparation
EP0027599A3 (en) * 1979-10-12 1981-07-15 Fujisawa Pharmaceutical Co. Ltd. Cephem compounds, processes for their preparation, pharmaceutical compositions containing them, intermediates and their preparation
EP0027599A2 (en) * 1979-10-12 1981-04-29 Fujisawa Pharmaceutical Co., Ltd. Cephem compounds, processes for their preparation and pharmaceutical compositions containing them
EP0034536A2 (fr) * 1980-02-18 1981-08-26 Roussel-Uclaf Nouvelles oximes dérivées de l'acide 3-alkyloxy ou 3-alkylthiométhyl 7-amino thiazolylacétamido céphalosporanique, leur préparation, leur application comme médicaments et les compositions les renfermant
EP0034536A3 (en) * 1980-02-18 1981-11-04 Roussel-Uclaf Oxime derivatives of 3-alkyloxy- or 3-alkylthiomethyl 7-amino-thiazolylacetamido cephalosporanic acid, their preparation, their use as medicaments, compositions containing them and intermediates obtained
EP0076528A2 (fr) * 1980-02-18 1983-04-13 Roussel-Uclaf Nouvelles oximes dérivées de l'acide 3-alkyloxy ou 3-alkylthiométhyl 7-amino thiazolylacétamido céphalosporanique et leur préparation
EP0076528A3 (en) * 1980-02-18 1983-08-24 Roussel-Uclaf Oxime derivatives of 3-alkyloxy or 3-alkylthiomethyl 7-amino-thiazolylacetamido-cephalosporanic acid and their preparation
EP0104671A3 (en) * 1980-02-18 1985-05-29 Roussel-Uclaf Oxime derivatives of 3-alkyloxy or 3-alkylthiomethyl-7-amino-thiazolylacetamido-cephalosporanic acid, their preparation, their use as medicines and compositions containing them
FR2532313A2 (fr) * 1980-02-18 1984-03-02 Roussel Uclaf Nouvelles oximes derivees de l'acide 3-alkyloxy ou 3-alkylthio-methyl 7-aminothiazolyl acetamido cephalosporanique, leur procede de preparation et leur application comme medicaments
EP0104671A2 (fr) * 1980-02-18 1984-04-04 Roussel-Uclaf Nouvelles oximes dérivées de l'acide 3-alkyloxy ou 3-alkylthiométhyl-7 amino thiazolylacétamido céphalosporaniques, leur préparation, leur application comme médicaments et les compositions les renfermant
EP0037797A2 (de) * 1980-03-11 1981-10-14 Ciba-Geigy Ag Cephalosporinverbindungen, Verfahren zu ihrer Herstellung, sie enthaltende pharmazeutische Zusammensetzungen und ihre Verwendung
EP0037797A3 (de) * 1980-03-11 1981-12-16 Ciba-Geigy Ag Cephalosporinverbindungen, Verfahren zu ihrer Herstellung, sie enthaltende pharmazeutische Zusammensetzungen und ihre Verwendung
EP0042154A1 (en) * 1980-06-18 1981-12-23 Fujisawa Pharmaceutical Co., Ltd. New cephem compounds and processes for preparation thereof
EP0045937A2 (en) * 1980-08-11 1982-02-17 Fujisawa Pharmaceutical Co., Ltd. New cephem compounds and processes for preparation thereof
EP0045937A3 (en) * 1980-08-11 1982-10-13 Fujisawa Pharmaceutical Co. Ltd. New cephem compounds and processes for preparation thereof
EP0046964A2 (en) * 1980-08-29 1982-03-10 Fujisawa Pharmaceutical Co., Ltd. New cephem compounds and processes for preparation thereof
EP0046964A3 (en) * 1980-08-29 1983-02-16 Fujisawa Pharmaceutical Co., Ltd. New cephem compounds and processes for preparation thereof
EP0184227A1 (en) * 1980-09-08 1986-06-11 Fujisawa Pharmaceutical Co., Ltd. 2-Oxymino 2-aminothiazolyl acetic acid derivatives and processes for preparation thereof
EP0047491A2 (en) * 1980-09-08 1982-03-17 Fujisawa Pharmaceutical Co., Ltd. New cephem compounds and processes for preparation thereof
EP0047491A3 (en) * 1980-09-08 1983-03-16 Fujisawa Pharmaceutical Co., Ltd. New cephem compounds and processes for preparation thereof
FR2509310A1 (fr) * 1980-09-25 1983-01-14 Toyama Chemical Co Ltd Nouvelles cephalosporines, leur procede de preparation et leur application en therapeutique
FR2511377A1 (fr) * 1980-09-25 1983-02-18 Toyama Chemical Co Ltd Nouvelles cephalosporines, et leurs sels
EP0049855B1 (de) * 1980-10-10 1986-01-29 F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft Neue Cephalosporinderivate, Verfahren zu ihrer Herstellung und Zwischenprodukte dafür sowie entsprechende pharmazeutische Präparate
EP0049855A2 (de) * 1980-10-10 1982-04-21 F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft Neue Cephalosporinderivate, Verfahren zu ihrer Herstellung und Zwischenprodukte dafür sowie entsprechende pharmazeutische Präparate
EP0053538A2 (fr) * 1980-11-20 1982-06-09 Rhone-Poulenc Sante Nouvelles vinyl-3 céphalosporines et leur préparation
EP0053073A1 (fr) * 1980-11-20 1982-06-02 Rhone-Poulenc Sante Nouvelles oxacéphalosporines et leur préparation
EP0053071A1 (fr) * 1980-11-20 1982-06-02 Rhone-Poulenc Sante Nouvelles oxacéphalosporines, leur préparation et les médicaments qui les contiennent
EP0053074A1 (fr) * 1980-11-20 1982-06-02 Rhone-Poulenc Sante Nouveaux dérivés de la céphalosporine et leur préparation
EP0053072A1 (fr) * 1980-11-20 1982-06-02 Rhone-Poulenc Sante Nouvelles oxacéphalosporines et leur préparation
EP0053542A1 (fr) * 1980-11-20 1982-06-09 Rhone-Poulenc Sante Nouveaux dérivés de la céphalosporine, leur préparation et les médicaments qui les contiennent
EP0053540A1 (fr) * 1980-11-20 1982-06-09 Rhone-Poulenc Sante Nouveaux dérivés de la céphalosporine et leur préparation
EP0053537A1 (fr) * 1980-11-20 1982-06-09 Rhone-Poulenc Sante Nouveaux dérivés de vinyl-3 céphalosporines et leur préparation
EP0053538A3 (en) * 1980-11-20 1982-09-22 Rhone-Poulenc Sante Vinyl-3 cephalosporin derivatives and their preparation
FR2494279A1 (fr) * 1980-11-20 1982-05-21 Rhone Poulenc Ind Nouvelles oxacephalosporines, leur preparation et les medicaments qui les contiennent
EP0053961A1 (fr) * 1980-11-20 1982-06-16 Rhone-Poulenc Sante Nouvelles thiovinyl-3 céphalosporines, leur préparation et les compositions pharmaceutiques qui les contiennent
EP0057422B1 (en) * 1981-02-02 1988-10-12 Fujisawa Pharmaceutical Co., Ltd. New cephem compounds, processes for preparation thereof and pharmaceutical composition containing them
EP0057422A2 (en) * 1981-02-02 1982-08-11 Fujisawa Pharmaceutical Co., Ltd. New cephem compounds, processes for preparation thereof and pharmaceutical composition containing them
FR2499995A1 (fr) * 1981-02-13 1982-08-20 Roussel Uclaf Nouvelles oximes derivees de l'acide 3-alkyloxy ou 3-alkylthiomethyl 7-amino thiazolylacetamido cephalosporanique, leur preparation, leur application comme medicaments, les compositions les renfermant et les nouveaux intermediaires obtenus.
FR2503712A1 (fr) * 1981-04-09 1982-10-15 Yamanouchi Pharma Co Ltd Composes de la cephalosporine et procede pour leur preparation
FR2505339A1 (fr) * 1981-05-11 1982-11-12 Rhone Poulenc Sante Nouvelles oxacephalosporines et leur preparation
FR2505338A1 (fr) * 1981-05-11 1982-11-12 Rhone Poulenc Sante Nouvelles oxacephalosporines et leur preparation
EP0070803A2 (de) * 1981-07-16 1983-01-26 Ciba-Geigy Ag Antibiotisch wirksame Aminotriazolyl-Cephalosporinderivate und ihre Herstellung
EP0070803A3 (de) * 1981-07-16 1984-05-02 Ciba-Geigy Ag Antibiotisch wirksame Aminotriazolyl-Cephalosporinderivate und ihre Herstellung
EP0074268A2 (en) * 1981-09-08 1983-03-16 Eli Lilly And Company Improvements in or relating to thieno and furopyridinium-substituted cephalosporin derivatives
EP0074268A3 (en) * 1981-09-08 1984-05-23 Eli Lilly And Company Improvements in or relating to thieno and furopyridinium-substituted cephalosporin derivatives
US4521413A (en) * 1981-09-14 1985-06-04 Fujisawa Pharmaceutical Co., Ltd. Cephem compounds
EP0076452A3 (de) * 1981-09-30 1984-09-05 Ciba-Geigy Ag Cephalosporinverbindungen, Verfahren zu ihrer Herstellung und sie enthaltende pharmazeutische Präparate
EP0076452A2 (de) * 1981-09-30 1983-04-13 Ciba-Geigy Ag Cephalosporinverbindungen, Verfahren zu ihrer Herstellung und sie enthaltende pharmazeutische Präparate
FR2514005A1 (fr) * 1981-10-02 1983-04-08 Lilly Co Eli Cephalosporines a substitution pyrazinium
EP0091130A2 (en) * 1982-04-06 1983-10-12 Daiichi Seiyaku Co., Ltd. Cephalosporin derivatives, process for preparing and pharmaceutical compositions containing said compounds
EP0091130A3 (en) * 1982-04-06 1984-07-25 Daiichi Seiyaku Co. Ltd. Cephalosporin derivatives, process for preparing and pharmaceutical compositions containing said compounds
EP0097961A3 (en) * 1982-06-28 1984-10-03 Bristol-Myers Company Cephalosporin derivatives, a process for the manufacture thereof and pharmaceutical compositions containing said derivatives
FR2530635A1 (fr) * 1982-07-23 1984-01-27 Servipharm Ltd Composes d'amino-imidazolyle, procede pour leur preparation, preparations pharmaceutiques contenant ces composes, et application de ces dernieres
US4598075A (en) * 1982-08-07 1986-07-01 Tanabe Seiyaku Co., Ltd. Cephalosporin compounds
EP0101265A3 (en) * 1982-08-07 1985-04-10 Tanabe Seiyaku Co., Ltd. Novel cephalosporin compounds and preparation thereof
EP0101265A2 (en) * 1982-08-07 1984-02-22 Tanabe Seiyaku Co., Ltd. Novel cephalosporin compounds and preparation thereof
FR2534922A1 (fr) * 1982-09-10 1984-04-27 Fujisawa Pharmaceutical Co Procede de preparation de composes de cephem et nouveaux produits ainsi que les compositions pharmaceutiques les renfermant
EP0103264A2 (en) * 1982-09-10 1984-03-21 Fujisawa Pharmaceutical Co., Ltd. New cephem compounds and processes for preparation thereof
EP0103264A3 (en) * 1982-09-10 1985-05-08 Fujisawa Pharmaceutical Co., Ltd. New cephem compounds and processes for preparation thereof
FR2533216A1 (fr) * 1982-09-22 1984-03-23 Toyama Chemical Co Ltd Nouvelles cephalosporines, et leurs sels
EP0122156A2 (en) * 1983-04-12 1984-10-17 Eli Lilly And Company Improvements in or relating to benzothienylglycyl cephalosporin derivatives
EP0122155A3 (en) * 1983-04-12 1985-07-31 Eli Lilly And Company Improvements in or relating to naphthylglycyl cephalosporin derivatives
EP0122157A3 (en) * 1983-04-12 1985-08-14 Eli Lilly And Company Improvements in or relating to indolylglycyl cephalosporin derivatives
EP0122154A3 (en) * 1983-04-12 1985-10-23 Eli Lilly And Company Improvements in or relating to benzothienylglycyl cephalosporin derivatives
EP0122156A3 (en) * 1983-04-12 1985-12-04 Eli Lilly And Company Improvements in or relating to benzothienylglycyl cephalosporin derivatives
EP0122157A2 (en) * 1983-04-12 1984-10-17 Eli Lilly And Company Improvements in or relating to indolylglycyl cephalosporin derivatives
EP0122154A2 (en) * 1983-04-12 1984-10-17 Eli Lilly And Company Improvements in or relating to benzothienylglycyl cephalosporin derivatives
EP0122155A2 (en) * 1983-04-12 1984-10-17 Eli Lilly And Company Improvements in or relating to naphthylglycyl cephalosporin derivatives
EP0135142A3 (en) * 1983-08-25 1986-01-08 Hoechst Aktiengesellschaft Cephalosporin derivatives and process for their preparation
EP0135142A2 (de) * 1983-08-25 1985-03-27 Hoechst Aktiengesellschaft Cephalosporinderivate und Verfahren zu ihrer Herstellung
EP0147181A3 (en) * 1983-12-21 1986-09-17 Tanabe Seiyaku Co., Ltd. Thiazolylacetic acid derivatives and their preparation
EP0147181A2 (en) * 1983-12-21 1985-07-03 Tanabe Seiyaku Co., Ltd. Thiazolylacetic acid derivatives and their preparation
FR2564095A1 (fr) * 1984-05-10 1985-11-15 Glaxo Group Ltd Antibiotiques de cephalosporine, leur preparation et compositions pharmaceutiques les contenant
EP0175610A3 (en) * 1984-09-07 1987-06-03 Meiji Seika Kaisha Ltd. New cephalosporin compounds and the production thereof
EP0175610A2 (en) * 1984-09-07 1986-03-26 Meiji Seika Kaisha Ltd. New cephalosporin compounds and the production thereof
EP0186586A2 (en) * 1984-12-20 1986-07-02 Meiji Seika Kaisha Ltd. Cephem compounds and the production thereof
EP0186586A3 (en) * 1984-12-20 1987-09-09 Meiji Seika Kaisha Ltd. New cephem compounds and the production thereof

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YU126772A (en) 1982-02-28
DK155187C (da) 1989-07-17
FR2137900B1 (pt) 1976-04-16
YU41807B (en) 1988-02-29
NO154797C (no) 1986-12-29
CY971A (en) 1978-12-22
IL39429A0 (en) 1972-07-26
PH11205A (en) 1977-10-28
YU321379A (en) 1982-02-28
DK155187B (da) 1989-02-27
MY7800466A (en) 1978-12-31
KE2895A (en) 1978-11-10
JPS5328141A (en) 1978-03-16
SE457795B (sv) 1989-01-30
ES402651A1 (es) 1975-11-01
IL39429A (en) 1978-04-30
ATA420872A (de) 1976-09-15
ES430104A1 (es) 1976-10-01
NL7206403A (pt) 1972-11-16
CS245754B2 (en) 1986-10-16
JPS54135792A (en) 1979-10-22
NO154797B (no) 1986-09-15
CA1027554A (en) 1978-03-07
DE2223375A1 (de) 1972-11-23
DE2223375C2 (de) 1985-05-15
NL166688C (nl) 1985-01-16
CS245753B2 (en) 1986-10-16
JPS531280B1 (pt) 1978-01-17
HK66078A (en) 1978-11-24
IE38172L (en) 1972-11-14
DE2265234A1 (de) 1976-12-30
AT336786B (de) 1977-05-25
IE38172B1 (en) 1978-01-18
FR2137900A1 (pt) 1972-12-29
NL166688B (nl) 1981-04-15
FR2137899B1 (pt) 1976-08-20
JPS6324993B2 (pt) 1988-05-23
CH591497A5 (pt) 1977-09-30
GB1399086A (en) 1975-06-25
BE783449A (fr) 1972-11-13
DE2265234C2 (de) 1983-02-10

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