FR2073416A1 - - Google Patents

Info

Publication number
FR2073416A1
FR2073416A1 FR7042531A FR7042531A FR2073416A1 FR 2073416 A1 FR2073416 A1 FR 2073416A1 FR 7042531 A FR7042531 A FR 7042531A FR 7042531 A FR7042531 A FR 7042531A FR 2073416 A1 FR2073416 A1 FR 2073416A1
Authority
FR
France
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7042531A
Other versions
FR2073416B1 (fr
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Boehringer Ingelheim Pharma GmbH and Co KG
Original Assignee
Dr Karl Thomae GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE19691959403 external-priority patent/DE1959403A1/de
Priority claimed from DE19702050814 external-priority patent/DE2050814A1/de
Priority claimed from DE19702050816 external-priority patent/DE2050816A1/de
Priority claimed from DE19702050815 external-priority patent/DE2050815A1/de
Application filed by Dr Karl Thomae GmbH filed Critical Dr Karl Thomae GmbH
Publication of FR2073416A1 publication Critical patent/FR2073416A1/fr
Application granted granted Critical
Publication of FR2073416B1 publication Critical patent/FR2073416B1/fr
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04—Ortho-condensed systems
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
FR7042531A 1969-11-26 1970-11-26 Expired FR2073416B1 (fr)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
DE19691959403 DE1959403A1 (de) 1969-11-26 1969-11-26 Neue 2-(5-Nitro-2-furyl)-thieno[3,2-d]pyrimidine und Verfahren zu ihrer Herstellung
DE19702050814 DE2050814A1 (de) 1970-10-16 1970-10-16 Neue Verfahren zur Herstellung von 2-(5-Nitro-2-furyl)-thieno eckige Klammer auf 3,2-d eckige Klammer zu pyrimidinen
DE19702050816 DE2050816A1 (de) 1970-10-16 1970-10-16 Neue 2-(Nitro-2-furyl>thieno eckige Klammer auf 3,2-d eckige Klammer zu pyrimidine
DE19702050815 DE2050815A1 (de) 1970-10-16 1970-10-16 Neue 2-(5-Nitro-2-furyl)-thieno eckige Klammer auf 3,2-d eckige Klammer zu pyrimidine

Publications (2)

Publication Number Publication Date
FR2073416A1 true FR2073416A1 (fr) 1971-10-01
FR2073416B1 FR2073416B1 (fr) 1975-04-18

Family

ID=27430978

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7042531A Expired FR2073416B1 (fr) 1969-11-26 1970-11-26

Country Status (13)

Country Link
US (1) US3661908A (fr)
BE (1) BE759493A (fr)
BG (2) BG17800A3 (fr)
CA (1) CA926865A (fr)
CH (3) CH567029A5 (fr)
DK (1) DK128781B (fr)
FR (1) FR2073416B1 (fr)
GB (1) GB1321316A (fr)
IE (1) IE34765B1 (fr)
IL (1) IL35729A (fr)
NL (1) NL7017210A (fr)
NO (1) NO129954B (fr)
SE (1) SE377938B (fr)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3932642A (en) * 1971-04-10 1976-01-13 Boehringer Ingelheim Gmbh Biocidal compositions containing a 2- (5'-nitro-2'-furyl)-thieno(2,3-d) pyrimidine and methods of use
US6187777B1 (en) 1998-02-06 2001-02-13 Amgen Inc. Compounds and methods which modulate feeding behavior and related diseases
US6608053B2 (en) * 2000-04-27 2003-08-19 Yamanouchi Pharmaceutical Co., Ltd. Fused heteroaryl derivatives
US20040138238A1 (en) * 2002-08-08 2004-07-15 Dhanoa Dale S. Substituted aminopyrimidine compounds as neurokinin antagonists
GB0423653D0 (en) * 2004-10-25 2004-11-24 Piramed Ltd Pharmaceutical compounds
CN101511840A (zh) 2006-04-26 2009-08-19 吉宁特有限公司 磷酸肌醇3-激酶抑制剂化合物及其使用方法
CN101472930B (zh) 2006-04-26 2011-12-14 霍夫曼-拉罗奇有限公司 用作PI3K抑制剂的噻吩并[3,2-d]嘧啶的衍生物
MX2008013584A (es) * 2006-04-26 2009-03-23 Genentech Inc Compuestos farmaceuticos.
TW200829594A (en) * 2006-12-07 2008-07-16 Piramed Ltd Phosphoinositide 3-kinase inhibitor compounds and methods of use
PE20081679A1 (es) * 2006-12-07 2008-12-18 Hoffmann La Roche Compuestos del inhibidor de fosfoinositida 3-cinasa y metodos de uso
JP5539190B2 (ja) * 2007-06-12 2014-07-02 エフ．ホフマン−ラ ロシュ アーゲー チアゾロピリミジン類及びホスファチジルイノシトール−３キナーゼのインヒビターとしてのそれらの使用
US7893059B2 (en) * 2007-09-24 2011-02-22 Genentech, Inc. Thiazolopyrimidine PI3K inhibitor compounds and methods of use
ES2439705T3 (es) * 2007-10-25 2014-01-24 Genentech, Inc. Proceso para la preparación de compuestos de tienopirimidina
GB0721095D0 (en) * 2007-10-26 2007-12-05 Piramed Ltd Pharmaceutical compounds
CA2753285A1 (fr) 2009-03-12 2010-09-16 Genentech, Inc. Combinaisons de composes inhibiteurs de phosphoinositide 3-kinase et d'agents chimiotherapeutiques pour le traitement de tumeurs malignes hematopoietiques
US8173650B2 (en) * 2009-05-27 2012-05-08 Genentech, Inc. Bicyclic pyrimidine PI3K inhibitor compounds selective for P110 delta, and methods of use
CA2772371A1 (fr) * 2009-05-27 2010-12-02 F. Hoffmann-La Roche Ag Composes bicycliques indole-pyrimidine inhibiteurs de pi3k selectifs pour p110 delta et leurs procedes d'utilisation
BR112012008483A2 (pt) * 2009-10-12 2019-09-24 Hoffmann La Roche combunações de um inibidor de pi3k e um inibidor de mex
CN103038643A (zh) 2010-04-16 2013-04-10 基因泰克公司 作为pi3k/akt激酶途径抑制剂效能的预测性生物标记的foxo3a
US20140004209A1 (en) 2010-12-22 2014-01-02 Genentech, Inc. Autophagy inducer and inhibitor combination therapy for the treatment of neoplasms
BR112015020054A2 (pt) 2013-02-25 2017-08-29 Genentech Inc Método de detectar resistência aos efeitos terapêuticos de um inibidor de akt em uma célula cancerosa

Also Published As

Publication number Publication date
FR2073416B1 (fr) 1975-04-18
CA926865A (en) 1973-05-22
IE34765L (en) 1971-05-26
IL35729A (en) 1974-01-14
BE759493A (fr) 1971-05-25
BG17799A3 (fr) 1973-12-25
NL7017210A (fr) 1971-05-28
CH559210A5 (fr) 1975-02-28
SE377938B (fr) 1975-08-04
CH567029A5 (fr) 1975-09-30
GB1321316A (en) 1973-06-27
CH568324A5 (fr) 1975-10-31
NO129954B (fr) 1974-06-17
US3661908A (en) 1972-05-09
BG17800A3 (fr) 1973-12-25
DK128781B (da) 1974-07-01
IL35729A0 (en) 1971-01-28
IE34765B1 (en) 1975-08-06

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Legal Events

Date Code Title Description
ST Notification of lapse