CA926865A - 2-(5-nitro-2-furyl)-thieno (3,2-d) pyrimidines and process for their production - Google Patents

2-(5-nitro-2-furyl)-thieno (3,2-d) pyrimidines and process for their production

Info

Publication number
CA926865A
CA926865A CA099166A CA99166A CA926865A CA 926865 A CA926865 A CA 926865A CA 099166 A CA099166 A CA 099166A CA 99166 A CA99166 A CA 99166A CA 926865 A CA926865 A CA 926865A
Authority
CA
Canada
Prior art keywords
thieno
pyrimidines
furyl
nitro
production
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
CA099166A
Other languages
English (en)
Inventor
Woitun Eberhard
Reuter Wolfgang
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Boehringer Ingelheim Pharma GmbH and Co KG
Original Assignee
Dr Karl Thomae GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE19691959403 external-priority patent/DE1959403A1/de
Priority claimed from DE19702050814 external-priority patent/DE2050814A1/de
Priority claimed from DE19702050815 external-priority patent/DE2050815A1/de
Priority claimed from DE19702050816 external-priority patent/DE2050816A1/de
Application filed by Dr Karl Thomae GmbH filed Critical Dr Karl Thomae GmbH
Application granted granted Critical
Publication of CA926865A publication Critical patent/CA926865A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04—Ortho-condensed systems
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
CA099166A 1969-11-26 1970-11-26 2-(5-nitro-2-furyl)-thieno (3,2-d) pyrimidines and process for their production Expired CA926865A (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
DE19691959403 DE1959403A1 (de) 1969-11-26 1969-11-26 Neue 2-(5-Nitro-2-furyl)-thieno[3,2-d]pyrimidine und Verfahren zu ihrer Herstellung
DE19702050814 DE2050814A1 (de) 1970-10-16 1970-10-16 Neue Verfahren zur Herstellung von 2-(5-Nitro-2-furyl)-thieno eckige Klammer auf 3,2-d eckige Klammer zu pyrimidinen
DE19702050815 DE2050815A1 (de) 1970-10-16 1970-10-16 Neue 2-(5-Nitro-2-furyl)-thieno eckige Klammer auf 3,2-d eckige Klammer zu pyrimidine
DE19702050816 DE2050816A1 (de) 1970-10-16 1970-10-16 Neue 2-(Nitro-2-furyl>thieno eckige Klammer auf 3,2-d eckige Klammer zu pyrimidine

Publications (1)

Publication Number Publication Date
CA926865A true CA926865A (en) 1973-05-22

Family

ID=27430978

Family Applications (1)

Application Number Title Priority Date Filing Date
CA099166A Expired CA926865A (en) 1969-11-26 1970-11-26 2-(5-nitro-2-furyl)-thieno (3,2-d) pyrimidines and process for their production

Country Status (13)

Country Link
US (1) US3661908A (fr)
BE (1) BE759493A (fr)
BG (2) BG17799A3 (fr)
CA (1) CA926865A (fr)
CH (3) CH559210A5 (fr)
DK (1) DK128781B (fr)
FR (1) FR2073416B1 (fr)
GB (1) GB1321316A (fr)
IE (1) IE34765B1 (fr)
IL (1) IL35729A (fr)
NL (1) NL7017210A (fr)
NO (1) NO129954B (fr)
SE (1) SE377938B (fr)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3932642A (en) * 1971-04-10 1976-01-13 Boehringer Ingelheim Gmbh Biocidal compositions containing a 2- (5'-nitro-2'-furyl)-thieno(2,3-d) pyrimidine and methods of use
US6187777B1 (en) 1998-02-06 2001-02-13 Amgen Inc. Compounds and methods which modulate feeding behavior and related diseases
US6608053B2 (en) * 2000-04-27 2003-08-19 Yamanouchi Pharmaceutical Co., Ltd. Fused heteroaryl derivatives
US20040138238A1 (en) * 2002-08-08 2004-07-15 Dhanoa Dale S. Substituted aminopyrimidine compounds as neurokinin antagonists
GB0423653D0 (en) * 2004-10-25 2004-11-24 Piramed Ltd Pharmaceutical compounds
TWI498332B (zh) * 2006-04-26 2015-09-01 Hoffmann La Roche 作為pi3k抑制劑之嘧啶衍生物及相關製備方法、醫藥組合物、用途、套組及產物
AR060632A1 (es) * 2006-04-26 2008-07-02 Genentech Inc Compuestos inhibidores de fosfoinositida 3- quinasa y metodos de uso
NZ572812A (en) 2006-04-26 2010-09-30 Hoffmann La Roche THIENO [3, 2-D] PYRIMIDINE Indazole DERIVATIVE USEFUL AS PI3K INHIBITOR
NZ578162A (en) * 2006-12-07 2011-12-22 Genentech Inc Phosphoinositide 3-kinase inhibitor compounds and methods of use
KR101507182B1 (ko) * 2006-12-07 2015-03-30 제넨테크, 인크. 포스포이노시타이드 3-키나제 억제제 화합물 및 그의 사용 방법
EP2158207B1 (fr) * 2007-06-12 2011-05-25 F. Hoffmann-La Roche AG Thiazolopyrimidines et leur utilisation comme inhibiteurs de la phosphatidylinositol-3 kinase (pi3k)
ES2399774T3 (es) * 2007-09-24 2013-04-03 Genentech, Inc. Compuestos de tiazolopirimidina inhibidores de PI3K y métodos de uso
EP2214675B1 (fr) 2007-10-25 2013-11-20 Genentech, Inc. Procédé de préparation de composés de thiénopyrimidine
GB0721095D0 (en) * 2007-10-26 2007-12-05 Piramed Ltd Pharmaceutical compounds
EP2405916B1 (fr) 2009-03-12 2018-02-07 Genentech, Inc. Combinaison de composés inhibiteurs de la phosphoinositide 3-kinase et d'agents chimiothérapeutiques pour le traitement de tumeurs malignes hématopoïétiques
CA2761445A1 (fr) 2009-05-27 2010-12-02 Genentech, Inc. Composes pyrimidines bicycliques inhibiteurs de pi3k selectifs pour p110 delta, et procedes d'utilisation
WO2010136491A1 (fr) * 2009-05-27 2010-12-02 F. Hoffmann-La Roche Ag Composés bicycliques indole-pyrimidine inhibiteurs de pi3k sélectifs pour p110 delta et leurs procédés d'utilisation
US20110086837A1 (en) * 2009-10-12 2011-04-14 Genentech, Inc. Combinations of a pi3k inhibitor and a mek inhibitor
MX2012011887A (es) 2010-04-16 2012-11-30 Genentech Inc Foxo 3a como biomarcador predictivo para la eficacia del inhibidor de la via de quinasa pi3k/akt.
WO2012088254A1 (fr) 2010-12-22 2012-06-28 Genentech, Inc. Polythérapie par inducteur et inhibiteur d'autophagie pour le traitement de néoplasmes
WO2014130923A2 (fr) 2013-02-25 2014-08-28 Genentech, Inc. Procédés et compositions pour détecter et traiter un mutant d'akt résistant aux médicaments

Also Published As

Publication number Publication date
FR2073416B1 (fr) 1975-04-18
NL7017210A (fr) 1971-05-28
US3661908A (en) 1972-05-09
IE34765L (en) 1971-05-26
BG17800A3 (bg) 1973-12-25
CH559210A5 (fr) 1975-02-28
GB1321316A (en) 1973-06-27
BG17799A3 (bg) 1973-12-25
DK128781B (da) 1974-07-01
SE377938B (fr) 1975-08-04
BE759493A (fr) 1971-05-25
NO129954B (fr) 1974-06-17
IL35729A0 (en) 1971-01-28
FR2073416A1 (fr) 1971-10-01
CH568324A5 (fr) 1975-10-31
IE34765B1 (en) 1975-08-06
CH567029A5 (fr) 1975-09-30
IL35729A (en) 1974-01-14

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