FR2070070A1 - Beta-amino-alpha-aryloxymethylacrylonitrile - and 2,4-diamino-5-benzylpyrimidine derivs. useful as antibacterial agents - Google Patents

Beta-amino-alpha-aryloxymethylacrylonitrile - and 2,4-diamino-5-benzylpyrimidine derivs. useful as antibacterial agents

Info

Publication number
FR2070070A1
FR2070070A1 FR7017799A FR7017799A FR2070070A1 FR 2070070 A1 FR2070070 A1 FR 2070070A1 FR 7017799 A FR7017799 A FR 7017799A FR 7017799 A FR7017799 A FR 7017799A FR 2070070 A1 FR2070070 A1 FR 2070070A1
Authority
FR
France
Prior art keywords
alpha
beta
diamino
amino
aryloxymethylacrylonitrile
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7017799A
Other languages
English (en)
French (fr)
Other versions
FR2070070B1 (de
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Wellcome Foundation Ltd
Original Assignee
Wellcome Foundation Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wellcome Foundation Ltd filed Critical Wellcome Foundation Ltd
Publication of FR2070070A1 publication Critical patent/FR2070070A1/fr
Application granted granted Critical
Publication of FR2070070B1 publication Critical patent/FR2070070B1/fr
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
    • C07D239/48—Two nitrogen atoms
    • C07D239/49—Two nitrogen atoms with an aralkyl radical, or substituted aralkyl radical, attached in position 5, e.g. trimethoprim
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C255/00—Carboxylic acid nitriles
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C317/00—Sulfones; Sulfoxides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/14—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D295/145—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with the ring nitrogen atoms and the carbon atoms with three bonds to hetero atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
    • C07D317/44—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D317/46—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems condensed with one six-membered ring
    • C07D317/48—Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring
    • C07D317/50—Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to atoms of the carbocyclic ring
    • C07D317/60—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
FR7017799A 1969-05-16 1970-05-15 Beta-amino-alpha-aryloxymethylacrylonitrile - and 2,4-diamino-5-benzylpyrimidine derivs. useful as antibacterial agents Granted FR2070070A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB2517169 1969-05-16

Publications (2)

Publication Number Publication Date
FR2070070A1 true FR2070070A1 (en) 1971-09-10
FR2070070B1 FR2070070B1 (de) 1974-10-11

Family

ID=10223379

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7017799A Granted FR2070070A1 (en) 1969-05-16 1970-05-15 Beta-amino-alpha-aryloxymethylacrylonitrile - and 2,4-diamino-5-benzylpyrimidine derivs. useful as antibacterial agents

Country Status (14)

Country Link
JP (1) JPS505184B1 (de)
AT (1) AT308082B (de)
BR (1) BR6915082D0 (de)
CA (1) CA994812A (de)
CH (1) CH544071A (de)
DE (1) DE2023977C2 (de)
ES (3) ES379700A1 (de)
FI (1) FI56375C (de)
FR (1) FR2070070A1 (de)
IL (1) IL34433A (de)
IT (1) IT1021507B (de)
NL (2) NL173395C (de)
PL (1) PL92440B1 (de)
SE (2) SE400777B (de)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1469521A (en) * 1973-01-05 1977-04-06 Wellcome Found Antimicrobial preparations
US4687861A (en) * 1984-11-28 1987-08-18 Ciba-Geigy Corporation Microbicidal compositions
BRPI0508461B8 (pt) * 2004-03-05 2021-05-25 Hoffmann La Roche diaminopirimidinas, seus usos, e composição farmacêutica

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR1266428A (fr) * 1960-09-02 1961-07-07 Wellcome Found Procédé de préparation de diamino-pyrimidines

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3049544A (en) * 1962-08-14 Method for the preparation of
DE1103931B (de) 1957-02-21 1961-04-06 Wellcome Found Verfahren zur Herstellung von 2, 4-Diamino-5-benzylpyrimidinderivaten
DE1303727B (de) 1959-09-03 1976-02-05 Ausscheidung aus: 14 45 176 The Wellcome Foundation Ltd., London Alpha-Arylidensubstituierte Propioni-Irile
DE1620729A1 (de) 1965-07-08 1970-08-20 Wellcome Found Verfahren zur Herstellung von substituierten Benzylpyrimidinen
GB1261455A (en) 1969-03-06 1972-01-26 Burroughs Wellcome Co Improvements in or relating to substituted acrylonitriles

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR1266428A (fr) * 1960-09-02 1961-07-07 Wellcome Found Procédé de préparation de diamino-pyrimidines

Also Published As

Publication number Publication date
SE400777B (sv) 1978-04-10
DE2023977A1 (de) 1971-02-18
BR6915082D0 (pt) 1973-03-08
AT308082B (de) 1973-06-25
CA994812A (en) 1976-08-10
CH544071A (de) 1973-11-15
SE398878B (sv) 1978-01-23
IT1021507B (it) 1978-02-20
IL34433A (en) 1971-10-20
NL173395B (nl) 1983-08-16
FI56375C (fi) 1980-01-10
DE2023977C2 (de) 1984-03-15
IL34433A0 (en) 1970-07-19
FR2070070B1 (de) 1974-10-11
NL8004796A (nl) 1980-11-28
ES406726A1 (es) 1975-10-01
ES406725A1 (es) 1975-10-01
ES379700A1 (es) 1973-01-16
PL92440B1 (en) 1977-04-30
NL173395C (nl) 1984-01-16
NL7007108A (de) 1970-11-18
FI56375B (fi) 1979-09-28
JPS505184B1 (de) 1975-02-28

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Legal Events

Date Code Title Description
ST Notification of lapse