CA994812A - Intermediates in the preparation of benzylpyrimidines - Google Patents
Intermediates in the preparation of benzylpyrimidinesInfo
- Publication number
- CA994812A CA994812A CA083,401A CA83401A CA994812A CA 994812 A CA994812 A CA 994812A CA 83401 A CA83401 A CA 83401A CA 994812 A CA994812 A CA 994812A
- Authority
- CA
- Canada
- Prior art keywords
- benzylpyrimidines
- intermediates
- preparation
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
- C07D239/48—Two nitrogen atoms
- C07D239/49—Two nitrogen atoms with an aralkyl radical, or substituted aralkyl radical, attached in position 5, e.g. trimethoprim
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C255/00—Carboxylic acid nitriles
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C317/00—Sulfones; Sulfoxides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/14—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D295/145—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with the ring nitrogen atoms and the carbon atoms with three bonds to hetero atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
- C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
- C07D317/44—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D317/46—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems condensed with one six-membered ring
- C07D317/48—Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring
- C07D317/50—Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to atoms of the carbocyclic ring
- C07D317/60—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB2517169 | 1969-05-16 |
Publications (1)
Publication Number | Publication Date |
---|---|
CA994812A true CA994812A (en) | 1976-08-10 |
Family
ID=10223379
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CA083,401A Expired CA994812A (en) | 1969-05-16 | 1970-05-19 | Intermediates in the preparation of benzylpyrimidines |
Country Status (14)
Country | Link |
---|---|
JP (1) | JPS505184B1 (en) |
AT (1) | AT308082B (en) |
BR (1) | BR6915082D0 (en) |
CA (1) | CA994812A (en) |
CH (1) | CH544071A (en) |
DE (1) | DE2023977C2 (en) |
ES (3) | ES379700A1 (en) |
FI (1) | FI56375C (en) |
FR (1) | FR2070070A1 (en) |
IL (1) | IL34433A (en) |
IT (1) | IT1021507B (en) |
NL (2) | NL173395C (en) |
PL (1) | PL92440B1 (en) |
SE (2) | SE400777B (en) |
Families Citing this family (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB1469521A (en) * | 1973-01-05 | 1977-04-06 | Wellcome Found | Antimicrobial preparations |
US4687861A (en) * | 1984-11-28 | 1987-08-18 | Ciba-Geigy Corporation | Microbicidal compositions |
JP4717876B2 (en) * | 2004-03-05 | 2011-07-06 | エフ.ホフマン−ラ ロシュ アーゲー | Diaminopyrimidines as P2X3 and P2X2 / 3 antagonists |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3049544A (en) * | 1962-08-14 | Method for the preparation of | ||
DE1103931B (en) | 1957-02-21 | 1961-04-06 | Wellcome Found | Process for the preparation of 2,4-diamino-5-benzylpyrimidine derivatives |
DE1303727B (en) | 1959-09-03 | 1976-02-05 | Ausscheidung aus: 14 45 176 The Wellcome Foundation Ltd., London | Alpha-arylidene-substituted propioni-iriles |
NL122146C (en) * | 1960-09-02 | |||
DE1620729A1 (en) | 1965-07-08 | 1970-08-20 | Wellcome Found | Process for the preparation of substituted benzylpyrimidines |
GB1261455A (en) | 1969-03-06 | 1972-01-26 | Burroughs Wellcome Co | Improvements in or relating to substituted acrylonitriles |
-
1969
- 1969-12-12 BR BR215082/69A patent/BR6915082D0/en unknown
-
1970
- 1970-03-05 PL PL1970177150A patent/PL92440B1/en unknown
- 1970-03-06 AT AT100472A patent/AT308082B/en active
- 1970-05-01 IL IL34433A patent/IL34433A/en unknown
- 1970-05-13 FI FI1338/70A patent/FI56375C/en active
- 1970-05-14 ES ES379700A patent/ES379700A1/en not_active Expired
- 1970-05-15 NL NLAANVRAGE7007108,A patent/NL173395C/en not_active IP Right Cessation
- 1970-05-15 DE DE2023977A patent/DE2023977C2/en not_active Expired
- 1970-05-15 IT IT50715/70A patent/IT1021507B/en active
- 1970-05-15 SE SE7006713A patent/SE400777B/en unknown
- 1970-05-15 FR FR7017799A patent/FR2070070A1/en active Granted
- 1970-05-15 CH CH732370A patent/CH544071A/en not_active IP Right Cessation
- 1970-05-15 JP JP45041540A patent/JPS505184B1/ja active Pending
- 1970-05-19 CA CA083,401A patent/CA994812A/en not_active Expired
-
1972
- 1972-09-15 ES ES406725A patent/ES406725A1/en not_active Expired
- 1972-09-15 ES ES406726A patent/ES406726A1/en not_active Expired
-
1973
- 1973-06-07 SE SE7308030A patent/SE398878B/en unknown
-
1980
- 1980-08-25 NL NL8004796A patent/NL8004796A/en not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
IT1021507B (en) | 1978-02-20 |
JPS505184B1 (en) | 1975-02-28 |
CH544071A (en) | 1973-11-15 |
ES406726A1 (en) | 1975-10-01 |
ES379700A1 (en) | 1973-01-16 |
AT308082B (en) | 1973-06-25 |
FR2070070A1 (en) | 1971-09-10 |
SE398878B (en) | 1978-01-23 |
IL34433A (en) | 1971-10-20 |
FI56375C (en) | 1980-01-10 |
FI56375B (en) | 1979-09-28 |
DE2023977C2 (en) | 1984-03-15 |
SE400777B (en) | 1978-04-10 |
NL173395B (en) | 1983-08-16 |
PL92440B1 (en) | 1977-04-30 |
NL8004796A (en) | 1980-11-28 |
NL173395C (en) | 1984-01-16 |
IL34433A0 (en) | 1970-07-19 |
BR6915082D0 (en) | 1973-03-08 |
ES406725A1 (en) | 1975-10-01 |
NL7007108A (en) | 1970-11-18 |
FR2070070B1 (en) | 1974-10-11 |
DE2023977A1 (en) | 1971-02-18 |
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