IT1021507B - PROCEDURE FOR PREPARING BY SYNTHESIS 2.4 DIAMOND 5 BENZYLPYRIMIDINES THEIR INTERMEDIATE COMPOUNDS AND RELATED PRODUCT FOR ANIMAL USE - Google Patents

PROCEDURE FOR PREPARING BY SYNTHESIS 2.4 DIAMOND 5 BENZYLPYRIMIDINES THEIR INTERMEDIATE COMPOUNDS AND RELATED PRODUCT FOR ANIMAL USE

Info

Publication number
IT1021507B
IT1021507B IT50715/70A IT5071570A IT1021507B IT 1021507 B IT1021507 B IT 1021507B IT 50715/70 A IT50715/70 A IT 50715/70A IT 5071570 A IT5071570 A IT 5071570A IT 1021507 B IT1021507 B IT 1021507B
Authority
IT
Italy
Prior art keywords
benzylpyrimidines
diamond
synthesis
preparing
procedure
Prior art date
Application number
IT50715/70A
Other languages
Italian (it)
Original Assignee
Wellcome Found
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wellcome Found filed Critical Wellcome Found
Application granted granted Critical
Publication of IT1021507B publication Critical patent/IT1021507B/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
    • C07D239/48—Two nitrogen atoms
    • C07D239/49—Two nitrogen atoms with an aralkyl radical, or substituted aralkyl radical, attached in position 5, e.g. trimethoprim
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C255/00—Carboxylic acid nitriles
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C317/00—Sulfones; Sulfoxides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/14—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D295/145—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with the ring nitrogen atoms and the carbon atoms with three bonds to hetero atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
    • C07D317/44—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D317/46—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems condensed with one six-membered ring
    • C07D317/48—Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring
    • C07D317/50—Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to atoms of the carbocyclic ring
    • C07D317/60—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
IT50715/70A 1969-05-16 1970-05-15 PROCEDURE FOR PREPARING BY SYNTHESIS 2.4 DIAMOND 5 BENZYLPYRIMIDINES THEIR INTERMEDIATE COMPOUNDS AND RELATED PRODUCT FOR ANIMAL USE IT1021507B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB2517169 1969-05-16

Publications (1)

Publication Number Publication Date
IT1021507B true IT1021507B (en) 1978-02-20

Family

ID=10223379

Family Applications (1)

Application Number Title Priority Date Filing Date
IT50715/70A IT1021507B (en) 1969-05-16 1970-05-15 PROCEDURE FOR PREPARING BY SYNTHESIS 2.4 DIAMOND 5 BENZYLPYRIMIDINES THEIR INTERMEDIATE COMPOUNDS AND RELATED PRODUCT FOR ANIMAL USE

Country Status (14)

Country Link
JP (1) JPS505184B1 (en)
AT (1) AT308082B (en)
BR (1) BR6915082D0 (en)
CA (1) CA994812A (en)
CH (1) CH544071A (en)
DE (1) DE2023977C2 (en)
ES (3) ES379700A1 (en)
FI (1) FI56375C (en)
FR (1) FR2070070A1 (en)
IL (1) IL34433A (en)
IT (1) IT1021507B (en)
NL (2) NL173395C (en)
PL (1) PL92440B1 (en)
SE (2) SE400777B (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1469521A (en) * 1973-01-05 1977-04-06 Wellcome Found Antimicrobial preparations
US4687861A (en) * 1984-11-28 1987-08-18 Ciba-Geigy Corporation Microbicidal compositions
KR100822530B1 (en) * 2004-03-05 2008-04-16 에프. 호프만-라 로슈 아게 Diaminopyrimidines as p2x3 and p2x2/3 antagonists

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3049544A (en) * 1962-08-14 Method for the preparation of
DE1103931B (en) 1957-02-21 1961-04-06 Wellcome Found Process for the preparation of 2,4-diamino-5-benzylpyrimidine derivatives
DE1303727B (en) 1959-09-03 1976-02-05 Ausscheidung aus: 14 45 176 The Wellcome Foundation Ltd., London Alpha-arylidene-substituted propioni-iriles
NL122146C (en) * 1960-09-02
DE1620729A1 (en) 1965-07-08 1970-08-20 Wellcome Found Process for the preparation of substituted benzylpyrimidines
GB1261455A (en) 1969-03-06 1972-01-26 Burroughs Wellcome Co Improvements in or relating to substituted acrylonitriles

Also Published As

Publication number Publication date
SE400777B (en) 1978-04-10
FR2070070B1 (en) 1974-10-11
FI56375C (en) 1980-01-10
NL8004796A (en) 1980-11-28
PL92440B1 (en) 1977-04-30
NL173395C (en) 1984-01-16
JPS505184B1 (en) 1975-02-28
AT308082B (en) 1973-06-25
CA994812A (en) 1976-08-10
BR6915082D0 (en) 1973-03-08
ES406725A1 (en) 1975-10-01
DE2023977A1 (en) 1971-02-18
IL34433A0 (en) 1970-07-19
IL34433A (en) 1971-10-20
NL173395B (en) 1983-08-16
ES406726A1 (en) 1975-10-01
FR2070070A1 (en) 1971-09-10
ES379700A1 (en) 1973-01-16
SE398878B (en) 1978-01-23
DE2023977C2 (en) 1984-03-15
FI56375B (en) 1979-09-28
NL7007108A (en) 1970-11-18
CH544071A (en) 1973-11-15

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