FR2034561A1 - 1-(substd-phenoxy)-3-isopropylamino-2-propa - nols as beta-adrenergie blocking agents - Google Patents

1-(substd-phenoxy)-3-isopropylamino-2-propa - nols as beta-adrenergie blocking agents

Info

Publication number
FR2034561A1
FR2034561A1 FR7006241A FR7006241A FR2034561A1 FR 2034561 A1 FR2034561 A1 FR 2034561A1 FR 7006241 A FR7006241 A FR 7006241A FR 7006241 A FR7006241 A FR 7006241A FR 2034561 A1 FR2034561 A1 FR 2034561A1
Authority
FR
France
Prior art keywords
substd
isopropylamino
phenoxy
beta
blocking agents
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7006241A
Other languages
English (en)
French (fr)
Other versions
FR2034561B1 (fi
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Imperial Chemical Industries Ltd
Original Assignee
Imperial Chemical Industries Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB47048/69A external-priority patent/GB1285038A/en
Application filed by Imperial Chemical Industries Ltd filed Critical Imperial Chemical Industries Ltd
Publication of FR2034561A1 publication Critical patent/FR2034561A1/fr
Application granted granted Critical
Publication of FR2034561B1 publication Critical patent/FR2034561B1/fr
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D303/00—Compounds containing three-membered rings having one oxygen atom as the only ring hetero atom
    • C07D303/02—Compounds containing oxirane rings
    • C07D303/12—Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms
    • C07D303/18—Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms by etherified hydroxyl radicals
    • C07D303/20—Ethers with hydroxy compounds containing no oxirane rings
    • C07D303/22—Ethers with hydroxy compounds containing no oxirane rings with monohydroxy compounds
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C243/00—Compounds containing chains of nitrogen atoms singly-bound to each other, e.g. hydrazines, triazanes
    • C07C243/24—Hydrazines having nitrogen atoms of hydrazine groups acylated by carboxylic acids
    • C07C243/26—Hydrazines having nitrogen atoms of hydrazine groups acylated by carboxylic acids with acylating carboxyl groups bound to hydrogen atoms or to acyclic carbon atoms
    • C07C243/30—Hydrazines having nitrogen atoms of hydrazine groups acylated by carboxylic acids with acylating carboxyl groups bound to hydrogen atoms or to acyclic carbon atoms to carbon atoms of an unsaturated carbon skeleton
    • C07C243/32—Hydrazines having nitrogen atoms of hydrazine groups acylated by carboxylic acids with acylating carboxyl groups bound to hydrogen atoms or to acyclic carbon atoms to carbon atoms of an unsaturated carbon skeleton the carbon skeleton containing rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/51—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by pyrolysis, rearrangement or decomposition
    • C07C45/54—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by pyrolysis, rearrangement or decomposition of compounds containing doubly bound oxygen atoms, e.g. esters
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/61—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
    • C07C45/62—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by hydrogenation of carbon-to-carbon double or triple bonds
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/61—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
    • C07C45/67—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton
    • C07C45/68—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms
    • C07C45/72—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms by reaction of compounds containing >C = O groups with the same or other compounds containing >C = O groups
    • C07C45/74—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms by reaction of compounds containing >C = O groups with the same or other compounds containing >C = O groups combined with dehydration
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C59/40—Unsaturated compounds
    • C07C59/42—Unsaturated compounds containing hydroxy or O-metal groups
    • C07C59/52—Unsaturated compounds containing hydroxy or O-metal groups a hydroxy or O-metal group being bound to a carbon atom of a six-membered aromatic ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C59/40—Unsaturated compounds
    • C07C59/42—Unsaturated compounds containing hydroxy or O-metal groups
    • C07C59/56—Unsaturated compounds containing hydroxy or O-metal groups containing halogen
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
    • C07D263/02—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
    • C07D263/04—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
    • C07D263/06—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with hydrocarbon radicals, substituted by oxygen atoms, attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D303/00—Compounds containing three-membered rings having one oxygen atom as the only ring hetero atom
    • C07D303/02—Compounds containing oxirane rings
    • C07D303/12—Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms
    • C07D303/18—Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms by etherified hydroxyl radicals
    • C07D303/20—Ethers with hydroxy compounds containing no oxirane rings
    • C07D303/24—Ethers with hydroxy compounds containing no oxirane rings with polyhydroxy compounds

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
FR7006241A 1969-02-21 1970-02-20 1-(substd-phenoxy)-3-isopropylamino-2-propa - nols as beta-adrenergie blocking agents Granted FR2034561A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB47048/69A GB1285038A (en) 1969-02-21 1969-02-21 Alkanolamine derivatives
GB944569 1969-02-21

Publications (2)

Publication Number Publication Date
FR2034561A1 true FR2034561A1 (en) 1970-12-11
FR2034561B1 FR2034561B1 (fi) 1974-05-24

Family

ID=26242944

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7006241A Granted FR2034561A1 (en) 1969-02-21 1970-02-20 1-(substd-phenoxy)-3-isopropylamino-2-propa - nols as beta-adrenergie blocking agents

Country Status (20)

Country Link
JP (2) JPS535287B1 (fi)
AT (3) AT305249B (fi)
BE (1) BE746107A (fi)
CA (1) CA945172A (fi)
CH (3) CH547257A (fi)
CS (3) CS153069B2 (fi)
DE (1) DE2007751C2 (fi)
DK (1) DK135278B (fi)
ES (1) ES376788A1 (fi)
FI (1) FI53120C (fi)
FR (1) FR2034561A1 (fi)
IE (1) IE34003B1 (fi)
IL (1) IL33931A (fi)
KE (1) KE2582A (fi)
NL (1) NL162363C (fi)
NO (1) NO128653B (fi)
PL (3) PL93998B1 (fi)
SE (1) SE391517B (fi)
SU (3) SU493062A3 (fi)
YU (4) YU34275B (fi)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2137587A1 (fi) * 1971-05-07 1972-12-29 Ici Ltd
FR2191898A1 (fi) * 1972-07-06 1974-02-08 Ici Ltd
FR2353520A1 (fr) * 1976-05-25 1977-12-30 Hoechst Ag 1-aryloxy-2-hydroxy-3-aminopropanes, leur procede de preparation et leurs applications therapeutiques

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1311521A (en) * 1970-02-13 1973-03-28 Ici Ltd Alkanolamine derivatives
DE2048838A1 (de) * 1970-10-05 1972-04-06 C H Boehnnger Sohn, 6507 Ingel heim Neue 1 Phenoxy 2 hydroxy 3 hydroxyal kylaminopropane und Verfahren zu ihrer Her stellung
FR2132570B1 (fi) * 1971-04-09 1974-08-02 Lipha
DE2818999A1 (de) * 1978-04-29 1979-11-15 Basf Ag Aminoderivate von 3-alkyl-5-(2- hydroxystyryl)-isoxazolen
DE2943405A1 (de) 1979-10-26 1981-05-07 Basf Ag, 6700 Ludwigshafen Neue aminoderivate des 5-(2-hydroxystyryl)-isoxazols
US4593119A (en) * 1980-11-28 1986-06-03 American Hospital Supply Corporation Method for treatment or prophylaxis of cardiac disorders
US4387103A (en) * 1980-11-28 1983-06-07 American Hospital Supply Corporation Method for treatment or prophylaxis of cardiac disorders
JPS57105206U (fi) * 1980-12-16 1982-06-29
DE3407695A1 (de) * 1984-03-02 1985-09-12 Röhm Pharma GmbH, 6108 Weiterstadt Pteridinverbindungen mit pharmazeutischer wirksamkeit
DE3500761A1 (de) * 1985-01-11 1986-09-04 SOUR "PODRAVKA" OOUR "BELUPO 2", Proizvodnja kozmetičkih preparata i lijekova, Koprivnica Verfahren zur gewinnung von atenolol und seiner derivate
US4971959A (en) * 1987-04-14 1990-11-20 Warner-Lambert Company Trisubstituted phenyl analogs having activity for congestive heart failure
WO1994013631A1 (en) * 1992-12-10 1994-06-23 Teikoku Chemical Industries Co., Ltd. Propionic acid derivative
CA2287920A1 (en) * 1997-04-30 1998-11-05 Eli Lilly And Company Intermediates and a process for preparing benzo¬b|thiophenes
JP5225574B2 (ja) * 2006-11-09 2013-07-03 エムキュア ファーマシューティカルズ リミテッド β遮断薬化合物の改善された調製方法
US8552036B2 (en) 2009-01-12 2013-10-08 Hetero Research Foundation Polymorph of atazanavir sulfate

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1593762A1 (de) * 1967-02-06 1972-06-08 Boehringer Sohn Ingelheim Verfahren zur Herstellung von neuen substituierten 1-Phenoxy-2-hydroxy-3-alkylaminopropanen

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
NEANT *

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2137587A1 (fi) * 1971-05-07 1972-12-29 Ici Ltd
FR2191898A1 (fi) * 1972-07-06 1974-02-08 Ici Ltd
FR2353520A1 (fr) * 1976-05-25 1977-12-30 Hoechst Ag 1-aryloxy-2-hydroxy-3-aminopropanes, leur procede de preparation et leurs applications therapeutiques

Also Published As

Publication number Publication date
DK135278B (da) 1977-03-28
IE34003L (en) 1970-08-21
IL33931A0 (en) 1970-04-20
DK135278C (fi) 1977-09-12
DE2007751A1 (fi) 1970-09-10
FR2034561B1 (fi) 1974-05-24
SU537626A3 (ru) 1976-11-30
CS153064B2 (en) 1974-02-22
YU41070A (en) 1978-10-31
YU34278B (en) 1979-04-30
JPS5037182B1 (fi) 1975-12-01
AT303005B (de) 1972-11-10
DE2007751C2 (de) 1983-12-15
PL87019B1 (en) 1976-06-30
PL77781B1 (en) 1975-04-30
CS153069B2 (fi) 1974-02-22
YU193475A (en) 1978-10-31
CS153062B2 (fi) 1974-02-22
SU482943A3 (ru) 1975-08-30
AT305249B (de) 1973-02-12
NL7002414A (fi) 1970-08-25
CA945172A (en) 1974-04-09
NL162363B (nl) 1979-12-17
FI53120B (fi) 1977-10-31
IE34003B1 (en) 1975-01-08
FI53120C (fi) 1978-02-10
YU34279B (en) 1979-04-30
YU193675A (en) 1978-10-31
CH547257A (de) 1974-03-29
YU34275B (en) 1979-04-30
NL162363C (nl) 1980-05-16
SU493062A3 (ru) 1975-11-25
YU193375A (en) 1978-10-31
NO128653B (fi) 1973-12-27
IL33931A (en) 1974-01-14
YU34281B (en) 1979-04-30
AT305244B (de) 1973-02-12
BE746107A (fr) 1970-08-17
KE2582A (en) 1975-12-05
JPS535287B1 (fi) 1978-02-25
ES376788A1 (es) 1972-09-16
SE391517B (sv) 1977-02-21
PL93998B1 (en) 1977-07-30
CH561175A5 (fi) 1975-04-30
CH553747A (de) 1974-09-13

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