FR05C0033I2 - R-enantiomere de n-propargyl-1-amino-indane pour le traitement des maladies diverses et son mesylate, esylate et sulfate - Google Patents
R-enantiomere de n-propargyl-1-amino-indane pour le traitement des maladies diverses et son mesylate, esylate et sulfateInfo
- Publication number
- FR05C0033I2 FR05C0033I2 FR05C0033C FR05C0033C FR05C0033I2 FR 05C0033 I2 FR05C0033 I2 FR 05C0033I2 FR 05C0033 C FR05C0033 C FR 05C0033C FR 05C0033 C FR05C0033 C FR 05C0033C FR 05C0033 I2 FR05C0033 I2 FR 05C0033I2
- Authority
- FR
- France
- Prior art keywords
- esylate
- indane
- propargyl
- mesylate
- enantiomer
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
- AFVFQIVMOAPDHO-UHFFFAOYSA-N Methanesulfonic acid Chemical compound CS(O)(=O)=O AFVFQIVMOAPDHO-UHFFFAOYSA-N 0.000 title 1
- QAOWNCQODCNURD-UHFFFAOYSA-L Sulfate Chemical compound [O-]S([O-])(=O)=O QAOWNCQODCNURD-UHFFFAOYSA-L 0.000 title 1
- 201000010099 disease Diseases 0.000 title 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 title 1
- CCIVGXIOQKPBKL-UHFFFAOYSA-M ethanesulfonate Chemical compound CCS([O-])(=O)=O CCIVGXIOQKPBKL-UHFFFAOYSA-M 0.000 title 1
- RUOKEQAAGRXIBM-UHFFFAOYSA-N n-prop-2-ynyl-2,3-dihydro-1h-inden-1-amine Chemical compound C1=CC=C2C(NCC#C)CCC2=C1 RUOKEQAAGRXIBM-UHFFFAOYSA-N 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C211/00—Compounds containing amino groups bound to a carbon skeleton
- C07C211/01—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to acyclic carbon atoms
- C07C211/26—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to acyclic carbon atoms of an unsaturated carbon skeleton containing at least one six-membered aromatic ring
- C07C211/30—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to acyclic carbon atoms of an unsaturated carbon skeleton containing at least one six-membered aromatic ring the six-membered aromatic ring being part of a condensed ring system formed by two rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/26—Psychostimulants, e.g. nicotine, cocaine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A61P25/32—Alcohol-abuse
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A61P25/36—Opioid-abuse
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2602/00—Systems containing two condensed rings
- C07C2602/02—Systems containing two condensed rings the rings having only two atoms in common
- C07C2602/04—One of the condensed rings being a six-membered aromatic ring
- C07C2602/08—One of the condensed rings being a six-membered aromatic ring the other ring being five-membered, e.g. indane
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Organic Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Psychiatry (AREA)
- Addiction (AREA)
- Epidemiology (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Pain & Pain Management (AREA)
- Immunology (AREA)
- Hospice & Palliative Care (AREA)
- Vascular Medicine (AREA)
- Emergency Medicine (AREA)
- Urology & Nephrology (AREA)
- Psychology (AREA)
- Ophthalmology & Optometry (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Fats And Perfumes (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US13951793A | 1993-10-18 | 1993-10-18 | |
PCT/US1994/011567 WO1995011016A1 (en) | 1993-10-18 | 1994-10-12 | R-enantiomer of n-propargyl-1-aminoindan, salts, compositions and uses thereof |
Publications (2)
Publication Number | Publication Date |
---|---|
FR05C0033I1 FR05C0033I1 (ja) | 2005-09-30 |
FR05C0033I2 true FR05C0033I2 (fr) | 2006-12-29 |
Family
ID=22487049
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
FR05C0033C Active FR05C0033I2 (fr) | 1993-10-18 | 2005-08-09 | R-enantiomere de n-propargyl-1-amino-indane pour le traitement des maladies diverses et son mesylate, esylate et sulfate |
Country Status (17)
Country | Link |
---|---|
EP (1) | EP0812190B1 (ja) |
JP (3) | JPH09505806A (ja) |
AT (1) | ATE284208T1 (ja) |
AU (1) | AU1253495A (ja) |
CA (1) | CA2174449C (ja) |
DE (2) | DE122005000044I2 (ja) |
DK (1) | DK0812190T3 (ja) |
ES (1) | ES2235170T3 (ja) |
FR (1) | FR05C0033I2 (ja) |
HU (1) | HU226138B1 (ja) |
IL (1) | IL111240A (ja) |
LU (1) | LU91191I2 (ja) |
MX (1) | MXPA94008019A (ja) |
NL (1) | NL300205I2 (ja) |
PT (1) | PT812190E (ja) |
WO (1) | WO1995011016A1 (ja) |
ZA (1) | ZA948013B (ja) |
Families Citing this family (57)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5744500A (en) * | 1990-01-03 | 1998-04-28 | Teva Pharmaceutical Industries, Ltd. | Use of R-enantiomer of N-propargyl-1-aminoindan, salts, and compositions thereof |
US5844003A (en) * | 1991-04-04 | 1998-12-01 | Innovations Foundation | Use of deprenyl compounds to maintain, prevent loss, or recover nerve cell function |
HU225986B1 (en) * | 1994-01-10 | 2008-02-28 | Teva Pharma | Use of 1-aminoindan derivatives for preparing pharmaceutical compns. and 1-aminoindan derivatives |
US5877218A (en) | 1994-01-10 | 1999-03-02 | Teva Pharmaceutical Industries, Ltd. | Compositions containing and methods of using 1-aminoindan and derivatives thereof and process for preparing optically active 1-aminoindan derivatives |
JPH10513455A (ja) * | 1995-02-10 | 1998-12-22 | ザ ユニバーシティ オブ トロント イノベーションズ ファウンデーション | 緑内障治療用のデプレニル化合物 |
NZ302723A (en) * | 1995-03-02 | 1998-04-27 | Scherer Ltd R P | Composition comprising monoamine oxidase b inhibitor and a carrier formulated for pre-gastric absorption of the monoamine oxidase b inhibitor |
IL115357A (en) * | 1995-09-20 | 2000-01-31 | Teva Pharma | Stable compositions containing N-propargyl-1-aminoindan and polyhydric alcohols |
IL118836A (en) * | 1996-07-11 | 2001-01-11 | Teva Pharma | Pharmaceutical compositions comprising s-(-)-n-propargyl-1-aminoindan |
IL119417A (en) * | 1996-10-13 | 2003-02-12 | Moshe Kushnir | Pharmaceutical composition for transdermal administration of levodopa for parkinson's disease |
PT966435E (pt) | 1996-12-18 | 2005-06-30 | Yissum Res Dev Co | Derivados aminoindano |
GB9715082D0 (en) * | 1997-07-17 | 1997-09-24 | Scherer Ltd R P | Treatment of attention deficit hyperactivity disorder and narcolepsy |
EP1052983A2 (en) * | 1998-01-27 | 2000-11-22 | Thomas N. Thomas | Use of an mao-a or mao-b inhibitor for the treatment of vascular disorders |
US6737547B1 (en) | 1998-12-31 | 2004-05-18 | Teva Pharmaceutical Industries, Ltd. | Compositions containing and methods of using N-acyl-1H-aminoindenes |
JP2003512426A (ja) | 1999-10-27 | 2003-04-02 | テバ ファーマシューティカル インダストリーズ リミティド | 双極性気分障害における躁病の治療のための1−アミノインダンの使用。 |
SI1567152T1 (sl) * | 2002-11-15 | 2013-10-30 | Teva Pharmaceutical Industries Ltd. | Uporaba rasagilina z riluzolom za zdravljenje amiotrofične lateralne skleroze |
AR044007A1 (es) * | 2003-04-11 | 2005-08-24 | Newron Pharmaceuticals Inc | Metodos para el tratamiento de la enfermedad de parkinson |
EP1588704A1 (en) * | 2004-04-22 | 2005-10-26 | Newron Pharmaceuticals S.p.A. | Alpha-aminoamide derivatives useful in the treatment of restless legs syndrome and addictive disorders |
NZ560660A (en) * | 2005-02-23 | 2010-11-26 | Teva Pharma | Rasagiline ( R(+)-N-propargyl-1-aminodan ) formulations of improved content uniformity |
AU2006316585B2 (en) | 2005-11-17 | 2012-09-20 | Teva Pharmaceutical Industries, Ltd. | Methods for isolating propargylated aminoindans |
US7572834B1 (en) | 2005-12-06 | 2009-08-11 | Teva Pharmaceutical Industries, Ltd. | Rasagiline formulations and processes for their preparation |
CA2634166C (en) | 2005-12-09 | 2016-03-29 | Marta Weinstock-Rosin | Use of low-dose ladostigil for neuroprotection |
AU2007217349B9 (en) * | 2006-02-21 | 2013-06-27 | Teva Pharmaceutical Industries, Ltd. | Use of rasagiline for the treatment of Multiple System Atrophy |
TW200744576A (en) | 2006-02-24 | 2007-12-16 | Teva Pharma | Propargylated aminoindans, processes for preparation, and uses thereof |
EP2007369A4 (en) * | 2006-04-03 | 2009-07-01 | Teva Pharma | USE OF RASAGILINE FOR THE TREATMENT OF LEG SYNDROME WITHOUT REST |
EP1892233A1 (de) * | 2006-08-18 | 2008-02-27 | Ratiopharm GmbH | Neue Salze des Wirkstoffs Rasagilin |
NZ577623A (en) | 2006-12-14 | 2011-05-27 | Teva Pharma | Tannate salt of rasagiline |
SI2101569T1 (sl) | 2006-12-14 | 2012-02-29 | Teva Pharma | Kristalinična trdna razagilinska baza |
WO2009032273A1 (en) * | 2007-09-05 | 2009-03-12 | Teva Pharmaceutical Industries, Ltd. | Method of treating glaucoma using rasagiline |
ATE513801T1 (de) * | 2007-12-24 | 2011-07-15 | Cipla Ltd | Verfahren zur synthese von propargylatierten aminoindanderivativen |
US20110117200A1 (en) * | 2008-03-31 | 2011-05-19 | Actavis Group Ptc Ehf | Rasagiline mesylate particles and process for the preparation thereof |
WO2009141737A2 (en) * | 2008-05-23 | 2009-11-26 | Medichem, S.A. | A new method for obtaining an aminoindan mesylate derivative |
EP2285769B1 (en) * | 2008-06-02 | 2014-08-13 | Generics [UK] Limited | A process for the preparation of enantiomerically pure amines |
AU2009254929B2 (en) * | 2008-06-02 | 2014-03-13 | Generics [Uk] Limited | An improved process for the preparation of amines |
AU2009260733B2 (en) * | 2008-06-19 | 2015-01-29 | Teva Pharmaceutical Industries, Ltd. | Process for purifying rasagiline base |
US20100010098A1 (en) | 2008-07-11 | 2010-01-14 | Walter Elffrink | Polymorphs of rasagiline hydrochloride |
US20100041920A1 (en) * | 2008-07-18 | 2010-02-18 | Stephen Benedict David Winter | New salt forms of an aminoindan derivative |
DE102008064061A1 (de) | 2008-12-19 | 2010-06-24 | Ratiopharm Gmbh | Feste Zusammensetzung mit dem Wirkstoff Rasagilin |
US20100189790A1 (en) | 2009-01-23 | 2010-07-29 | Teva Pharmaceutical Industries, Ltd. | Delayed release rasagiline formulation |
PL2451771T3 (pl) * | 2009-07-09 | 2014-12-31 | Ratiopharm Gmbh | Sole rasagiliny i ich preparaty farmaceutyczne |
CN102048717B (zh) † | 2009-10-29 | 2014-02-19 | 重庆医药工业研究院有限责任公司 | 一种稳定的雷沙吉兰组合物 |
EP2325159A1 (en) | 2009-11-24 | 2011-05-25 | LEK Pharmaceuticals d.d. | Novel salts of rasagiline |
WO2011087791A1 (en) | 2009-12-22 | 2011-07-21 | Teva Pharmaceutical Industries Ltd. | 3-keto-n-propargyl-1-aminoindan |
WO2011080589A2 (en) | 2009-12-30 | 2011-07-07 | Actavis Group Ptc Ehf | Solid state forms of rasagiline salts |
SG183150A1 (en) * | 2010-02-03 | 2012-09-27 | Pharma Two B Ltd | Extended release formulations of rasagiline and uses thereof |
WO2011121607A2 (en) | 2010-03-29 | 2011-10-06 | Cadila Healthcare Limited | Rasagiline and its pharmaceutically acceptable salts |
EP2389927A1 (en) | 2010-05-30 | 2011-11-30 | Abdi Ibrahim Ilac Sanayi ve Ticaret Anonim Sirketi | Pharmaceutical formulations of rasagiline |
CN102464589A (zh) * | 2010-11-17 | 2012-05-23 | 凯瑞斯德生化(苏州)有限公司 | 雷沙吉兰、其甲磺酸盐及其中间体的制备方法 |
WO2012096635A1 (en) | 2011-01-13 | 2012-07-19 | Fargem Farmasöti̇k Araştirma Geli̇şti̇rme Merkezi̇ Sanayi̇ Ve Ti̇caret A.Ş. | A new method for the synthesis of rasagiline |
EP2681186B1 (en) | 2011-03-03 | 2016-05-11 | Synthon BV | Process of resolution of 1-aminoindan |
EP2705021A2 (en) | 2011-05-04 | 2014-03-12 | Cadila Healthcare Limited | Rasagiline and its pharmaceutically acceptable salts |
BR112014008555A2 (pt) * | 2011-10-10 | 2017-04-18 | Teva Pharma | r(+)-n-formil-propargil-aminoindano |
DE102012000786A1 (de) | 2012-01-18 | 2013-07-18 | Stada Arzneimittel Ag | Verfahren zur Herstellung einer festen pharmazeutischen Zusammensetzung, enthaltend den Wirkstoff Rasagilin |
EP2827848B1 (en) | 2012-03-21 | 2016-04-27 | Synthon BV | Stabilized pharmaceutical compositions comprising rasagiline salts |
WO2013175493A1 (en) | 2012-04-09 | 2013-11-28 | Cadila Healthcare Limited | Stable oral pharmaceutical compositions |
EP2796130A3 (en) | 2013-02-06 | 2015-02-25 | Galenicum Health S.L. | Immediate release tablets of rasagiline hemitartrate |
ES2502140T1 (es) | 2013-02-06 | 2014-10-02 | Galenicum Health S.L. | Comprimidos de liberación inmediata de rasagilina hemitartrato |
WO2014192022A1 (en) * | 2013-05-20 | 2014-12-04 | Cadila Healthcare Limited | Pharmaceutical compositions of rasagiline |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB1187017A (en) * | 1966-07-16 | 1970-04-08 | Aspro Nicholas Ltd | Substituted 1-Amino Indanes and Tetrahydronaphthalens |
ATE76747T1 (de) * | 1986-06-10 | 1992-06-15 | Chiesi Farma Spa | Levodopa-methyl-ester enthaltende pharmazeutische zusammensetzungen, ihre herstellung und therapeutische verwendungen. |
IL92952A (en) * | 1990-01-03 | 1994-06-24 | Teva Pharma | R-enantiomers of n-propargyl-1-aminoindan compounds, their preparation and pharmaceutical compositions containing them |
IL112819A (en) * | 1991-10-16 | 2001-11-25 | Teva Pharma | Fluorinated 1-aminoindan compounds and a process for their preparation |
-
1994
- 1994-10-11 IL IL11124094A patent/IL111240A/en not_active IP Right Cessation
- 1994-10-12 WO PCT/US1994/011567 patent/WO1995011016A1/en active IP Right Grant
- 1994-10-12 AT AT95903505T patent/ATE284208T1/de active
- 1994-10-12 DK DK95903505T patent/DK0812190T3/da active
- 1994-10-12 CA CA002174449A patent/CA2174449C/en not_active Expired - Lifetime
- 1994-10-12 JP JP7512014A patent/JPH09505806A/ja not_active Withdrawn
- 1994-10-12 DE DE200512000044 patent/DE122005000044I2/de active Active
- 1994-10-12 ES ES95903505T patent/ES2235170T3/es not_active Expired - Lifetime
- 1994-10-12 PT PT95903505T patent/PT812190E/pt unknown
- 1994-10-12 HU HU9601012A patent/HU226138B1/hu active Protection Beyond IP Right Term
- 1994-10-12 DE DE69434178T patent/DE69434178T2/de not_active Expired - Lifetime
- 1994-10-12 EP EP95903505A patent/EP0812190B1/en not_active Expired - Lifetime
- 1994-10-12 AU AU12534/95A patent/AU1253495A/en not_active Abandoned
- 1994-10-13 ZA ZA948013A patent/ZA948013B/xx unknown
- 1994-10-17 MX MXPA94008019A patent/MXPA94008019A/es active IP Right Grant
-
2002
- 2002-10-17 JP JP2002303097A patent/JP2003160481A/ja not_active Withdrawn
-
2005
- 2005-08-09 FR FR05C0033C patent/FR05C0033I2/fr active Active
- 2005-08-10 LU LU91191C patent/LU91191I2/fr unknown
- 2005-08-15 NL NL300205C patent/NL300205I2/nl unknown
-
2009
- 2009-09-24 JP JP2009219662A patent/JP2010018626A/ja active Pending
Also Published As
Publication number | Publication date |
---|---|
NL300205I1 (nl) | 2005-10-03 |
LU91191I2 (fr) | 2005-10-10 |
ES2235170T3 (es) | 2005-07-01 |
CA2174449C (en) | 2007-01-16 |
EP0812190B1 (en) | 2004-12-08 |
DE122005000044I2 (de) | 2007-09-13 |
NL300205I2 (nl) | 2006-03-01 |
EP0812190A1 (en) | 1997-12-17 |
DE69434178D1 (de) | 2005-01-13 |
HU9601012D0 (en) | 1996-06-28 |
ATE284208T1 (de) | 2004-12-15 |
DK0812190T3 (da) | 2005-04-11 |
IL111240A0 (en) | 1994-12-29 |
ZA948013B (en) | 1995-05-31 |
JP2003160481A (ja) | 2003-06-03 |
HUT77934A (hu) | 1998-11-30 |
IL111240A (en) | 2001-10-31 |
MXPA94008019A (es) | 2004-08-10 |
AU1253495A (en) | 1995-05-08 |
DE69434178T2 (de) | 2005-12-01 |
PT812190E (pt) | 2005-04-29 |
JP2010018626A (ja) | 2010-01-28 |
JPH09505806A (ja) | 1997-06-10 |
DE122005000044I1 (de) | 2005-12-22 |
HU226138B1 (en) | 2008-05-28 |
EP0812190A4 (en) | 1998-03-04 |
CA2174449A1 (en) | 1995-04-27 |
FR05C0033I1 (ja) | 2005-09-30 |
WO1995011016A1 (en) | 1995-04-27 |
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